Laregab NT 400/10mg Tablet 10'S
Key Information
Generic Name
Generic Name Gabapentin 400 mg+Nortriptyline 10 mg
Manufacturer
La Renon Healthcare Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
LAREGAB NT 400/10MG TABLET is a combination of Gabapentin and Nortriptyline which belongs to the group of medicines called Anticonvulsant and Antidepressants respectively. LAREGAB NT 400/10MG TABLET is used to manage neuropathic pain in adults. Neuropathic pain is caused due to damage to the sensory nerves usually due to chronic progressive nerve disease, infection, or injury. The pain could be occasional or continuous, which is thought of as a prickling, stabbing, tingling, or burning sensation. Avoid consumption of alcohol while taking LAREGAB NT 400/10MG TABLET as it may lead to more dizziness. If you have self-harming thoughts, contact your physician or go to the hospital straight away. LAREGAB NT 400/10MG TABLET is not recommended to use if you had a recent heart attack or heartbeat disorder, heart block, or coronary artery disease. Consult your doctor before taking. LAREGAB NT 400/10MG TABLET should not be used among women who are pregnant or breastfeeding mothers. LAREGAB NT 400/10MG TABLET is not recommended for use in children and adolescents (below 18 years of age). It should be used with caution in elderly patients (above 65 years of age). The most common
Uses
OF LAREGAB NT 400/10MG TABLET Used to manage neuropathic pain
How It Works
LAREGAB NT 400/10MG TABLET is a combination of Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels, which in turn helps in relieving nerve pain. Nortriptyline works by increasing the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of signals of pain in the brain. Together Gabapentin and Nortriptyline relieve neuropathic pain (pain from damaged nerves).
Directions for Use
Take LAREGAB NT 400/10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects
LAREGAB NT 400/10MG TABLET are viral infection, feeling drowsy, dizziness, lack of coordination, feeling tired, constipation, nausea, headache, tremor, and fever. Consult your doctor for advice if your symptoms get worsen over time. USES OF LAREGAB NT 400/10MG TABLET Used to manage neuropathic pain HOW LAREGAB NT 400/10MG TABLET WORKSLAREGAB NT 400/10MG TABLET is a combination of Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels, which in turn helps in relieving nerve pain. Nortriptyline works by increasing the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of signals of pain in the brain. Together Gabapentin and Nortriptyline relieve neuropathic pain (pain from damaged nerves). DIRECTIONS FOR USETake LAREGAB NT 400/10MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. SIDE EFFECTS OF LAREGAB NT 400/10MG TABLETCOMMON Dry mouth Excessive sweating Constipation Nausea Headache Tremor Blocked nose Accommodation disorder of the eyes Irregular or heavy heartbeat Weight gain Aggression Strange body movements Flushing Weakness fatigue Dizziness Confusion Problem in the heart called prolonged QT interval Changes in taste Blurred vision Decreases in libido and erectile dysfunction Agitation Tingling in arms and legs Problems urinating Feeling thirsty Low sodium concentration in the blood Viral infection High blood pressure, dilation of blood vessels Difficulty breathing, sore throat, cough, bronchitis, dry nose Vomiting (being sick), problems with teeth, inflamed gums, diarrhea, stomach pain, indigestion, or throat, flatulence Facial swelling, bruises, rash, itch, acne Pain in the joints, muscles, and back, and twitching Swelling in the legs and arms, difficulty in walking, feeling unwell, weakness, pain, flu-like symptoms Decrease in the number of white blood cells, increase in weight Accidental injury, abrasion, fracture UNCOMMON Swelling that may involve the limbs, face, and trunk Abnormal blood test results (problems with the liver) Mental impairment Increase in blood glucose levels Difficulty swallowing Changes in sleep patterns (including nightmares) Increased production or outflow of breast milk without breastfeeding RARE Respiratory depression (trouble breathing, shallow breaths) Confusional states (delirium) Hallucinations Hair loss Enlargement of male breast tissue Stop taking LAREGAB NT 400/10MG TABLET and contact your physician immediately if you experience any of the following side effects: Muscle pain and/or weakness or tenderness Signs such as persistent stomach pain, feeling sick, and being sick (acute pancreatitis) (inflamed pancreas) Swelling of the lips, tongue, and face, skin rash and redness, and/or hair loss, hives, fever, swollen glands that do not go away Yellowing of the skin or of the whites of the eyes, unusual bruising or bleeding, severe fatigue or weakness, and unexpected muscle pain Breathing problems
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredLAREGAB NT 400/10MG TABLET is not recommended to use in pregnant women unless considered clearly necessary. Consult your doctor before taking the medicine. BREASTFEEDINGContraindicatedLAREGAB NT 400/10MG TABLET is contraindicated for breastfeeding women. Consult your doctor before taking LAREGAB NT 400/10MG TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines or do anything that needs alertness or clear vision after taking LAREGAB NT 400/10MG TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking LAREGAB NT 400/10MG TABLET as it may lead to more dizziness. Consult your doctor before taking LAREGAB NT 400/10MG TABLET. KIDNEYUse with CautionLAREGAB NT 400/10MG TABLET should be taken with caution in patients with kidney problems including haemodialysis. Consult your doctor before taking. LIVERContraindicatedLAREGAB NT 400/10MG TABLET is not recommended for patients with severe liver diseases. Consult your doctor before taking. ALLERGYContraindicatedDo not take LAREGAB NT 400/10MG TABLET if you are allergic to Gabapentin, Nortriptyline or any other tricyclic antidepressants (Ex. amitriptyline) or to any other ingredients of this medicine. HEART DISEASEConsult your doctorLAREGAB NT 400/10MG TABLET is not recommended for patients who had recent myocardial infarction, any degree of heart block or other cardiac arrhythmias. It should be used with patients with mild to moderate heart disease. Consult your doctor before taking. USE IN PEDIATRICSContraindicatedLAREGAB NT 400/10MG TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking. USE IN GERIATRICSUse with CautionLAREGAB NT 400/10MG TABLET should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking LAREGAB NT 400/10MG TABLET. OTHERSLAREGAB NT 400/10MG TABLET is not recommended if you: Suffer from mania (abnormally raised mood) Before taking LAREGAB NT 400/10MG TABLET, inform your doctor if you have: Nervous system disorders Respiratory disorders Suicidal thoughts or aggressive behaviour Schizophrenia, bipolar disorder Thyroid conditions A history of epilepsy High pressure in the eyes (glaucoma) An enlarged prostate Diabetes Difficulty in passing urine Paralytic ileus (blocked intestine) and pylorus stenosis (narrowing of the gastric outlet) Excessive fever (hyperpyrexia) Undergo electroconvulsive therapy
Drug Interactions
SA. Drug-Drug interactions: Before taking LAREGAB NT 400/10MG TABLET, inform your doctor if you are taking any of the following medicine: Medicines used as monoamine oxidase inhibitors (Ex. phenelzine, moclobemide, iproniazid, isocarboxazid, nialamide or tranylcypromine (used to manage depression) or selegiline (used to manage Parkinson's disease) Medicines used to manage opioid dependence (Ex. buprenorphine) Medicines used in cough or cold medicine, and in some anesthetics (Ex. adrenaline, isoprenaline, ephedrine, noradrenaline, phenylephrine, and phenylpropanolamine) Medicine used to manage high blood pressure (Ex. diltiazem and verapamil) (Ex. guanethidine, bethanidine, debrisoquine, clonidine reserpine, and methyldopa) Medicines used to manage Parkinson’s disease and gastrointestinal disorders (Ex. atropine, hyoscyamine) Medicine used to manage schizophrenia (Ex. thioridazine) Medicine used as a painkiller (Ex. tramadol) Medicines to manage fungal infections (Ex. fluconazole, terbinafine, ketoconazole, and itraconazole) Medicine used as sedatives (Ex. barbiturates) Medicine used as antidepressants (Ex. fluoxetine, paroxetine, fluvoxamine), and bupropion) Medicines used to manage certain heart conditions (Ex. beta-blockers and antiarrhythmics) Medicine used to manage stomach ulcers (Ex. cimetidine) Medicine used to manage ADHD (Ex. methylphenidate) Oral contraceptives Medicine used to manage infections (Ex. rifampicin) Medicine used to manage epilepsy (Ex. phenytoin and carbamazepine) An herbal remedy used for depression (Ex. St. John’s Wort) Medicine used for thyroid problems Medicines used to manage heart rhythm (Ex. amiodarone, cisapride, dofetilide, pimozide, procainamide, quinidine, sotalol) Overdosage: If you or anyone else accidentally takes too much of LAREGAB NT 400/10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include blurred vision, fast or irregular heartbeats, difficulties passing water, dry mouth and tongue, intestinal blockage, fits, fever, agitation, confusion, hallucinations, uncontrolled movements, low blood pressure, weak pulse, pallor, difficulty breathing, blue discoloration of the skin, decreased heart rate. SYNOPSIS Drug : Gabapentin, Nortriptyline Pharmacological Category : Anticonvulsants, Antidepressants Therapeutic Indication : Neuropathic pain Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep LAREGAB NT 400/10MG TABLET out of reach to children Store at a temperature, not more than 30°C
Frequently Asked Questions
Common questions and answers about Laregab NT 400/10mg Tablet 10'S.
What is LAREGAB NT 400/10MG TABLET used for?
LAREGAB NT 400/10MG TABLET is used to manage neuropathic pain. Neuropathic pain is caused due to damage to the sensory nerves usually due to chronic progressive nerve disease, infection, or injury. Consult your doctor before taking it.
Is LAREGAB NT 400/10MG TABLET safe to use in pregnancy?
LAREGAB NT 400/10MG TABLET is generally not recommended to use in pregnant women unless considered clearly necessary. Consult your doctor before taking LAREGAB NT 400/10MG TABLET.
Can LAREGAB NT 400/10MG TABLET be used in patients with heart problems?
LAREGAB NT 400/10MG TABLET should not be used in patients with heart problems like a recent heart attack or heartbeat disorder, heart block, or coronary artery disease. Consult your doctor before taking LAREGAB NT 400/10MG TABLET.
Can I drink alcohol along with LAREGAB NT 400/10MG TABLET?
Avoid consumption of alcohol while taking LAREGAB NT 400/10MG TABLET as it may lead to more dizziness. Consult your doctor before taking LAREGAB NT 400/10MG TABLET.
Is LAREGAB NT 400/10MG TABLET can be used in children?
LAREGAB NT 400/10MG TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
26 Jul 2024