JOLAVI Tablet 10's
Key Information
Generic Name
Generic Name Midodrine 2.5 mg
Manufacturer
Jolly Healthcare
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
JOLAVI TABLET contains Midodrine which belongs to the group of medicines called Alpha -1 Selective Adrenergic Receptor Agonist. It is used to manage low blood pressure (hypotension) in adults. Symptoms of low blood pressure include blurred or fading vision, dizziness or light-headedness, fainting, feeling sick, difficult in concentrating. Midodrine acts on the blood vessels via the sympathetic nervous system (part of nervous system that cause increase in heart rate, blood pressure, breathing rate, and dilatation of pupil) to correct imbalances of blood distribution, such as preventing too much blood pooling in the legs when standing up which may cause low blood pressure. Your doctor may regularly monitor the blood pressure when you are lying down and when you are standing up as there may be a risk of your blood pressure rising when you lie down (Ex. at night). JOLAVI TABLET is not recommended for use in patients having severe heart disease.JOLAVI TABLET should be used with caution in patient having severe kidney disease, liver problems. Consult your doctor for advice before takingJOLAVI TABLET, if you are pregnant or breast-feeding.JOLAVI TABLET is not recommended for use in children and adolescents below the age of 18 years. The most common
Uses
OF JOLAVI TABLET Used to manage certain severe forms of low blood pressure in adults by increasing the blood pressure
How It Works
JOLAVI TABLET acts on the blood vessels via the sympathetic nervous system (part of nervous system that cause increase in heart rate, blood pressure, breathing rate, and dilatation of pupil) to correct the imbalances of blood distribution, such as preventing too much blood pooling in the legs when standing up which may cause low blood pressure.
Directions for Use
TakeJOLAVI TABLET as advised by your physician. Swallow this medicine, do not crush, or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
takingJOLAVI TABLET are increased blood pressure when lying down, headache, nausea (feeling sick), vomiting, heartburn. Consult your doctor if the symptom worsens. USES OF JOLAVI TABLET Used to manage certain severe forms of low blood pressure in adults by increasing the blood pressure HOW JOLAVI TABLET WORKSJOLAVI TABLET acts on the blood vessels via the sympathetic nervous system (part of nervous system that cause increase in heart rate, blood pressure, breathing rate, and dilatation of pupil) to correct the imbalances of blood distribution, such as preventing too much blood pooling in the legs when standing up which may cause low blood pressure. DIRECTIONS FOR USETakeJOLAVI TABLET as advised by your physician. Swallow this medicine, do not crush, or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF JOLAVI TABLETCOMMON Pain when urinating Tingling and itching Increased blood pressure when lying down Headache Nausea (feeling sick), vomiting Heartburn Inflammation of the lining inside the mouth Flushing Rash Chills Difficulty in urinating UNCOMMON Sleep disturbances including difficulty sleeping Restlessness Agitation (state of anxiety), irritability Slowed heart rate Urge to urinate RARE Rapid, irregular or fast heartbeat Chest pain Signs of increased liver enzymes such stomach pain, dark urine, fatigue (feeling tired), itching, jaundice (yellowing of your skin or eyes) Dizziness or light headedness Stroke Visual disturbances
Warnings & Precautions
. Talk to your doctor if the symptom worsens. HeadacheApply hot or cold-water bag on your head. Try taking rest in a quiet and dark room. Massage with mild pressure on scalp or head. Nausea And VomitingTake this medicine with, or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks, and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Consult your doctor if your symptom does not improve. WARNING & PRECAUTIONSPREGNANCYContraindicatedJOLAVI TABLET is not recommended for use in pregnant. Consult your doctor before takingJOLAVI TABLET. BREASTFEEDINGContraindicatedJOLAVI TABLET is not recommended for use during breast-feeding. Discuss with your doctor before takingJOLAVI TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you feel dizzy or lightheaded after takingJOLAVI TABLET. Consult your doctor before takingJOLAVI TABLET. KIDNEYContraindicatedJOLAVI TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before takingJOLAVI TABLET. LIVERUse with CautionJOLAVI TABLET should be used with caution in patients having liver impairment. Consult your doctor before takingJOLAVI TABLET. ALLERGYContraindicatedJOLAVI TABLET is not recommended for use if you are allergic to Midodrine. HEART DISEASEContraindicatedJOLAVI TABLET is not recommended for use in patients with severe heart disease including slow pulse, heart attack, heart failure, heart rhythm disorders, widening of the aorta (aortic aneurysm) or other cardiovascular diseases and also in patients with high blood pressure, or a form of low blood pressure known as vasovagal hypotension. Consult your doctor before takingJOLAVI TABLET. USE IN PEDIATRICSContraindicatedJOLAVI TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before takingJOLAVI TABLET. USE IN GERIATRICSUse with CautionJOLAVI TABLET is used with caution in patients above 60 years of age. Usually the management is initiated with the lowest dose and gradually increased depending upon the clinical condition of the patient. Consult your doctor before takingJOLAVI TABLET. OTHERSJOLAVI TABLET is not recommended for use if you have: Difficulty in urinating Have elevated pressure in the eye (glaucoma) or poor vision because of diabetes Hyperthyroidism (overactive thyroid gland) Hormonal disorders caused by a tumour in the adrenal medulla (pheochromocytoma) Enlarged prostate Before takingJOLAVI TABLET, inform your doctor if you have: Serious disorder of the nervous system (autonomic nervous system disorders) Problems with blood circulation Disease of the prostate
Drug Interactions
SA. Drug-Drug interactions: Reserpine and guanethidine (medicines used to reduce high blood pressure) Antihistamines like cetirizine, chlorpheniramine (used to manage allergies) Hormones for the thyroid like thyroxine Tricyclic antidepressants like clomipramine, amoxapine, amitriptyline and MAO-inhibitors such as selegiline, isocarboxazid, phenelzine, (both used to manage depression) Vasoconstrictors like epinephrine, dopamine, phenyl epinephrine (medicines that narrow blood vessels) Sympathomimetic agents such as ephedrine, isoproterenol, metaproterenol, (medicines that have a stimulating effect on certain parts of the nervous system) Prazosin and phentolamine (medicines used to manage heart disease Digitalis preparations such as digitoxin, digoxin (medicines used to manage heart disease) Fludrocortisone acetate (medicine used to reduce inflammation) Perphenazine (medicine used to manage mental or mood disorders) Amiodarone (medicine used to manage irregular heartbeat) Metoclopramide (medicine used to prevent vomiting) Overdosage: If you or anyone else accidentally take too much ofJOLAVI TABLET, consult your doctor immediately or visit the nearby hospital. The most common symptoms of overdose are high blood pressure (hypertension), slow heart rate (bradycardia), difficulty urinating and feeling of coldness. SYNOPSIS Drug : Midodrine Pharmacological Category : Alpha -1 Selective Adrenergic Receptor Agonist Therapeutic Indication : Low blood pressure Dosage Forms : Tablet MORE INFORMATIONSTORAGE KeepJOLAVI TABLET out of reach of children Store at room temperature
Frequently Asked Questions
Common questions and answers about JOLAVI Tablet 10's.
CanJOLAVI TABLET cause heart palpitations?
Yes,JOLAVI TABLET may cause irregular and fast heartbeat as it is one of the side effects of this medicine. This may result in the risk of falling down. Other symptoms include blurred vision, weakness, or tiredness, feeling sick. Consult your doctor immediately if you experience any abnormal heartbeat or signs of abnormal heartbeat (such as chest pain, dizziness, fainting).
How doesJOLAVI TABLET works?
JOLAVI TABLET acts on the blood vessels via the sympathetic nervous system (part of nervous system that cause increase in heart rate, blood pressure, breathing rate, and dilatation of pupil) to correct the imbalances of blood distribution, such as preventing too much blood pooling in the legs when standing up which may cause low blood pressure.
Is it safe to useJOLAVI TABLET in older patients?
Yes, but it should be used with caution in elderly with regular monitoring of blood pressure levels and your doctor may monitor your vital organs as it may cause damage to liver, kidney, and heart.
What happens if I stop takingJOLAVI TABLET?
Do not stop takingJOLAVI TABLET without talking to your doctor first. Stopping this medicine suddenly can cause your blood pressure to fall and may increase the risk of blurred vision, dizziness, fainting or death.
Who should not takeJOLAVI TABLET?
You should not useJOLAVI TABLET if you have severe heart disease, overactive thyroid, an adrenal gland tumour, kidney disease, heart disease, liver disease, painful urination, or if your blood pressure is high even while lying down. Consult your doctor immediately if you experience any unusual effects.
Article Information
Written By
ity (HPRA). [Revised in August 2021] [Accessed 20th May 2022] http://www.hpra.ie/img/uploaded/swedocuments/56f4c194-cebb-4cee-b24e-b8ce367e433c.pdf 5. MIAS Pharma Limited. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed 20th May 2022] https://www.medicines.org.uk/emc/files/pil.12496.pdf 6. Shire US Inc. U.S. Food & Drug Administration. [Revised in January 2017] [Accessed 20th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019815s010lbl.pdf USEFUL DIAGNOSTIC TESTS Kidney function test AUTHOR DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
11 Jul 2024