JAKAUTO Gel 20g
Key Information
Generic Name
Generic Name Tofacitinib 2 %
Manufacturer
Eris Oaknet Healthcare Pvt Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT JAKAUTO GELJAKAUTO GEL is used to manage mild to moderate atopic dermatitis (AD), such as dry, itchy, swollen, and red skin. It contains Tofacitinib, which belongs to the group of medicines called Janus Kinase Inhibitors. It suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, JAKAUTO GEL blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis. Apply JAKAUTO GEL to the affected area as directed by your doctor to get the most benefit. Prior to the initiation of this medicine, your doctor may order blood tests to understand and monitor your existing condition. JAKAUTO GEL is not recommended for use in pregnant women and breastfeeding women or if you are suffering from active tuberculosis (TB) or severe liver disease. It should be used with caution in patients with a history of chronic lung disease or interstitial lung disease due to the increased risk of infections. The safety and efficacy of JAKAUTO GEL in children are not established. Therefore, consult your child’s doctor for advice before using this medicine. The most common
Uses
OF JAKAUTO GEL It is used to manage signs of mild to moderate atopic dermatitis such as (skin rashes, redness, peeling, dryness, flakiness, bumps or fissures)
How It Works
JAKAUTO GEL suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs) in the body. This action blocks the production of pro-inflammatory substances (including cytokines) within the body that contributes to the development of inflammation and other symptoms of atopic dermatitis.
Directions for Use
Apply JAKAUTO GEL as advised by your doctor. It is for external use only. Apply JAKAUTO GEL as a thin layer to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of JAKAUTO GEL for you depending upon your age, body weight, and disease condition.
Side Effects
using JAKAUTO GEL are application site eczema, application site itching, and fever. Consult your doctor if any of the side effects worsen. USES OF JAKAUTO GEL It is used to manage signs of mild to moderate atopic dermatitis such as (skin rashes, redness, peeling, dryness, flakiness, bumps or fissures) HOW JAKAUTO GEL WORKSJAKAUTO GEL suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs) in the body. This action blocks the production of pro-inflammatory substances (including cytokines) within the body that contributes to the development of inflammation and other symptoms of atopic dermatitis. DIRECTIONS FOR USEApply JAKAUTO GEL as advised by your doctor. It is for external use only. Apply JAKAUTO GEL as a thin layer to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of JAKAUTO GEL for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF JAKAUTO GELCOMMON Application site eczema Application site itching Fever Stop taking JAKAUTO GEL and contact your physician immediately if you experience any of the following side effects: Serious infection, an opportunistic infection, or sepsis Serious allergic reactions such as urticaria and angioedema Signs of myocardial infarction or stroke
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedJAKAUTO GEL is not recommended for use by pregnant women. Women of childbearing potential should be advised to use effective contraception during therapy with JAKAUTO GEL and for at least 4 weeks after the last dose. Therefore, consult your doctor before using it. BREASTFEEDINGContraindicatedJAKAUTO GEL is not recommended for use by breastfeeding women. Therefore, consult your doctor before using it. DRIVING AND USING MACHINESUse with CautionJAKAUTO GEL has no influence on the ability to drive or operate machinery. LIVERContraindicatedJAKAUTO GEL is not recommended for use if you have severe liver disease. Therefore, consult your doctor before using it. ALLERGYContraindicatedDo not use JAKAUTO GEL if you are allergic to tofacitinib or any of the other ingredients in this medicine. LUNGSConsult your doctorJAKAUTO GEL is not recommended for use if you have active tuberculosis (TB). It should be used with caution in patients with a history of chronic lung disease or developed interstitial lung disease due to the increased risk of infections. Therefore, consult your doctor before using it. USE IN PEDIATRICSConsult your doctorThe safety and efficacy of JAKAUTO GEL in children are not established. Therefore, consult your child’s doctor for advice. OTHERSJAKAUTO GEL is not recommended for use if you: Have serious infections, such as sepsis, or opportunistic infections Have a low white blood cell count Have low levels of haemoglobin Before using JAKAUTO GEL, inform your doctor if you: Have a chronic or recurrent infection Have been exposed to tuberculosis History of a serious or an opportunistic infection Have resided or travelled in areas of endemic tuberculosis or endemic mycoses Have underlying conditions that may predispose to infections Have herpes zoster (due to virus reactivation) Have an increased risk of thrombosis (blood clots)
Drug Interactions
SA. Drug-Drug interactions: Antifungals (Ex. ketoconazole, fluconazole) Anti-tubercular agent (Ex. rifampicin) Immunosuppressants (Ex. tacrolimus, ciclosporin) Live vaccines Overdosage: If you applied too much of JAKAUTO GEL, rinse with plenty of water. If irritation persists, consult your doctor for advice. SYNOPSIS Drug : Tofacitinib Pharmacological Category : Janus Kinase Inhibitors Therapeutic Indication : Atopic dermatitis Dosage Forms : Gel MORE INFORMATIONSTORAGE Keep JAKAUTO GEL out of reach of children Store at room temperature not exceeding 30ºC. Do not freeze
Frequently Asked Questions
Common questions and answers about JAKAUTO Gel 20g.
What is JAKAUTO GEL used for?
JAKAUTO GEL is used to manage mild to moderate atopic dermatitis (AD) such as dry, itchy, swollen, and red skin. Consult your doctor before using it.
How does JAKAUTO GEL work?
JAKAUTO GEL suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, JAKAUTO GEL blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis.
How should I apply JAKAUTO GEL?
Apply JAKAUTO GEL as advised by your doctor. It is for external use only. Apply JAKAUTO GEL to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of JAKAUTO GEL for you depending upon your age, body weight, and disease condition.
Is JAKAUTO GEL safe during pregnancy?
JAKAUTO GEL is not recommended for use by pregnant women. Women of childbearing potential should be advised to use effective contraception during treatment with JAKAUTO GEL and for at least 4 weeks after the last dose. Consult your doctor before using it.
Can JAKAUTO GEL be used with children?
The safety and efficacy of JAKAUTO GEL in children are not established. Consult your child’s doctor for advice.
Can I use JAKAUTO GEL daily?
Apply a thin layer of JAKAUTO GEL twice daily to affected areas for 4 consecutive weeks or as directed by the physician. It is for topical use only. Tofacitinib ointment 2% w/w is not for ophthalmic, oral, or intravaginal use.
What are the side effects of using JAKAUTO GEL?
The most common side effects of using JAKAUTO GEL are application site eczema, application site itching, and fever. Consult your doctor if any of the side effects worsen.
Who should not use JAKAUTO GEL?
JAKAUTO GEL is not recommended for use if you have active tuberculosis (TB), severe liver disease, are allergic to Tofacitinib, have serious infections such as sepsis or opportunistic infections, have a low white blood cell count, or have low levels of haemoglobin. Consult your doctor before using it.
What precautions must be taken while using JAKAUTO GEL?
Before using JAKAUTO GEL, inform your doctor if you have a history of chronic lung disease, interstitial lung disease, chronic or recurrent infection, have been exposed to tuberculosis, have a history of a serious or an opportunistic infection, or if you have resided or travelled in areas of endemic tuberculosis or endemic mycoses, have underlying conditions that may predispose to infections, a decrease in white blood cell count, herpes zoster (due to virus reactivation), or have an increased risk of thrombosis (blood clots).
Can I use other medicines along with JAKAUTO GEL?
Before using JAKAUTO GEL, inform your doctor if you are taking prescription, non-prescription, or herbal medicines.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
22 Jun 2024