ISOLAZINE Tablet 15's

Angina (210)Rx required

Key Information

Generic Name

Generic Name Hydralazine 37.5 mg+Isosorbide Dinitrate 20 mg

Manufacturer

Lupin Ltd

Variant

15 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

ISOLAZINE TABLET is a combination of Hydralazine and Isosorbide dinitrate which belongs to the group of medicines called Vasodilators. It is used to manage heart failure along with standard therapy in patients to improve survival, delay hospitalization for heart failure and to improve patient-reported functional status. Heart failure is defined as a progressive clinical disorder where your heart is unable to pump sufficient blood to meet the body’s metabolic needs, characterized by shortness of breath and extreme tiredness. During course of the management your doctor might regularly monitor your blood pressure to avoid any untoward

Uses

OF ISOLAZINE TABLET Manage heart failure

How It Works

ISOLAZINE TABLET helps in the management of heart failure, where hydralazine relaxes the smooth muscles of arteries and isosorbide dinitrate acts by releasing nitric oxide and subsequently activating guanylyl cyclase and ultimately relaxes smooth muscles of both arteries and veins.

Directions for Use

Take ISOLAZINE TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects

ISOLAZINE TABLET in children have not been established. Before taking ISOLAZINE TABLET, inform your doctor if you have any kidney, heart, lung or liver problems, too much sweating, fluid loss, vomiting or diarrhea or if you consume alcohol. ISOLAZINE TABLET is not studied in pregnant and breastfeeding women, so consult your doctor before taking it. The most common side effects of taking ISOLAZINE TABLET are headache and dizziness. Consult your doctor if any of the side effects worsen. USES OF ISOLAZINE TABLET Manage heart failure HOW ISOLAZINE TABLET WORKSISOLAZINE TABLET helps in the management of heart failure, where hydralazine relaxes the smooth muscles of arteries and isosorbide dinitrate acts by releasing nitric oxide and subsequently activating guanylyl cyclase and ultimately relaxes smooth muscles of both arteries and veins. DIRECTIONS FOR USETake ISOLAZINE TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF ISOLAZINE TABLETCOMMON headache dizziness RAREStop taking ISOLAZINE TABLET and consult your doctor immediately if you experience any of the following side effects: allergic reaction (signs include rash, hives, itching, red, swollen, blistered or peeling skin, wheezing, tightness in the chest or throat, difficulty breathing, swallowing or talking, unusual hoarseness or swelling of the mouth, face, lips, tongue or throat) lupus-like rash on the cheeks or other body parts, easy sunburn, muscle or joint pain, chest pain or breathlessness or swelling in the arms or legs low blood pressure (very bad dizziness or passing out) fever insufficient oxygen supply to heart muscle and angina (chest pain or pressure or a fast heartbeat) peripheral neuritis (numbness, prickling and tingling sensation)

Warnings & Precautions

& PRECAUTIONSPREGNANCYISOLAZINE TABLET is not studied in pregnant women. Consult your doctor before taking it. BREASTFEEDINGISOLAZINE TABLET is not studied in breastfeeding women. Consult your doctor before taking this medicine as it is not known if it passes into breast milk. DRIVING AND USING MACHINESDo not drive or use any machines until you see how ISOLAZINE TABLET affects you. ALCOHOLAvoid consumption of alcohol during management with ISOLAZINE TABLET as it may increase the risk of vasodilating effects of this medicine. KIDNEYISOLAZINE TABLET is not studied in patients with kidney impairment. Consult your doctor before taking it. LIVERISOLAZINE TABLET is not studied in patients with liver impairment. Consult your doctor before taking it. ALLERGYDo not take ISOLAZINE TABLET if you are allergic to Hydralazine or Isosorbide dinitrate. HEART DISEASEISOLAZINE TABLET should be used with caution in patients with hypertrophic cardiomyopathy. Consult your doctor before taking it. OTHERSBefore taking ISOLAZINE TABLET, inform your doctor if you: have too much sweating, fluid loss, vomiting or diarrhea Use in pediatrics: Safety and effectiveness of ISOLAZINE TABLET in children and adolescents (aged less than 18 years) have not been established. Consult your child’s doctor for advice. Use in geriatrics: ISOLAZINE TABLET should be used with caution in elderly patients. Consult your doctor before taking it.

Drug Interactions

SA. Drug - Drug interactions: Before taking ISOLAZINE TABLET, inform your doctor if you are taking any of the following medicines: medicines used to manage erectile dysfunction (Ex. avanafil, sildenafil, tadalafil, vardenafil) riociguat (used to manage high blood pressure in the vessels that carry blood to the lungs) Overdosage: If you or anyone else accidentally took too much of ISOLAZINE TABLET, contact your doctor immediately. Symptoms of overdose include headache, confusion, fast heartbeat, generalized skin flushing, reduced cardiac output, low blood pressure, irregular heartbeat and shock. SYNOPSIS Drug : Hydralazine, Isosorbide dinitrate Pharmacological Category : Vasodilators Therapeutic Indication : As adjunct to standard management in heart failure Dosage Forms : Tablet MORE INFORMATION Keep ISOLAZINE TABLET out of reach of children Store at room temperature

Frequently Asked Questions

Common questions and answers about ISOLAZINE Tablet 15's.

Q

What do I need to inform my doctor before taking ISOLAZINE TABLET?

A

Before taking ISOLAZINE TABLET, inform your doctor about all the medicines that you are taking (prescription or OTC, herbal products, vitamins) and your health problems. This is necessary to make sure that it is safe for you to take this medicine with all your other medicines and health problems. Do not start, stop or change the dose of any medicine without consulting your doctor.

Q

How does ISOLAZINE TABLET work?

A

ISOLAZINE TABLET helps in the management of heart failure, where hydralazine relaxes the smooth muscles of arteries and isosorbide dinitrate acts by releasing nitric oxide and subsequently activating guanylyl cyclase and ultimately relaxes smooth muscles of both arteries and veins.

Q

Can ISOLAZINE TABLET make me feel dizzy?

A

ISOLAZINE TABLET may cause a drop in your blood pressure that may make you feel dizzy. If this happens, resting or lying down for some time can help. Rise slowly after sitting or lying down. Be careful while going up and down stairs. Consult your doctor if you experience persistent dizziness.

Q

Does ISOLAZINE TABLET cause headache?

A

Yes, headache is a side effect of ISOLAZINE TABLET. Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache.

Q

Can ISOLAZINE TABLET be used in children?

A

The safety and effectiveness of ISOLAZINE TABLET in children and adolescents (aged less than 18 years) have not been established. Your child’s doctor will select a suitable alternative therapy for your child to manage the condition.

Article Information

DW

Written By

DETAILS Written By Dr. R. Dinesh John Rajkumar

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

19 Jan 2023

Tags

#angina (210)#generic name hydralazine 37.5 mg+isosorbide dinitrate 20 mg