Instgra 50mg Tablet 30'S
Key Information
Generic Name
Generic Name Dolutegravir 50 mg
Manufacturer
Emcure Pharmaceuticals Ltd
Variant
30 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INSTGRA 50MG TABLET contains Dolutegravir which belongs to the group of medicines called Integrase inhibitors. INSTGRA 50MG TABLET is used to manage HIV (Human Immunodeficiency Virus) infection in adults, and children (aged 6 years/above) who should weigh at-least 14 kg/above. INSTGRA 50MG TABLET is not recommended for use in patients allergic to Dolutegravir. Before taking INSTGRA 50MG TABLET, inform your doctor if you are suffering from advanced HIV infection and/or have weak immune system (prone to serious infections), kidney problems (such as mild to severe renal impairment), and liver problems (such as mild to moderate hepatic impairment). INSTGRA 50MG TABLET should be used with caution during pregnancy only if it is clearly necessary since the medicine may increase the risk of birth defect (such as neural tube defect/malformed spinal cord) in unborn baby. It is generally not recommended for use in breastfeeding women as the medicine may pass through breastmilk. INSTGRA 50MG TABLET is not recommended for use in children (aged below 6 years) and in children who weigh less than 14 kg and who are resistant to other medicines similar to INSTGRA 50MG TABLET. It is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor. The most common
Uses
OF INSTGRA 50MG TABLET Manage HIV (human immunodeficiency virus) infection in affected individuals
How It Works
INSTGRA 50MG TABLET works by reducing the amount of virus in the body which results in increased count of CD4 cell (white blood cell that helps body to fight infection) in blood managing HIV and managing the occurrence other infections in affected individuals.
Directions for Use
Take INSTGRA 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects
taking INSTGRA 50MG TABLET are headache, stomach pain, nausea, vomiting, diarrhea, itching, and/or rash. Consult your doctor if any of the symptoms worsen. USES OF INSTGRA 50MG TABLET Manage HIV (human immunodeficiency virus) infection in affected individuals HOW INSTGRA 50MG TABLET WORKSINSTGRA 50MG TABLET works by reducing the amount of virus in the body which results in increased count of CD4 cell (white blood cell that helps body to fight infection) in blood managing HIV and managing the occurrence other infections in affected individuals. DIRECTIONS FOR USETake INSTGRA 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF INSTGRA 50MG TABLETCOMMON headache stomach pain, nausea, vomiting, diarrhea, wind rash, itching, stomach pain/discomfort sleeplessness, dizziness abnormal dreams, depression, anxiety lack of energy (fatigue) UNCOMMON inflammation of the liver (hepatitis) suicide attempt, suicidal thoughts joint/muscle pain RARE signs of liver failure such as yellowing of skin and the whites of the eyes/unusually dark urine. Stop taking INSTGRA 50MG TABLET and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions such as skin rash, fever, lack of energy, swelling of face/mouth, difficulty in breathing, and/or muscle/joint aches signs of infection such as fever, chills, shortness of breath, and/or nasal congestion
Warnings & Precautions
& PRECAUTIONSPREGNANCYINSTGRA 50MG TABLET should be used with caution during pregnancy only if it is clearly necessary since the medicine may increase the risk of birth defect (such as neural tube defect/malformed spinal cord) in unborn baby. Women of childbearing potential should use contraceptive measures (such as condoms/pills) while in management with INSTGRA 50MG TABLET to manage pregnancy and should inform doctor immediately if accidental pregnancy occurs. Consult your doctor before taking the medicine. BREASTFEEDINGINSTGRA 50MG TABLET is generally not recommended for use in breastfeeding women as the medicine may pass through breastmilk. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESDo not drive or operate machines, if you feel dizzy or have other side effects that make you less alert after taking INSTGRA 50MG TABLET. ALCOHOLAvoid consumption of alcohol while taking INSTGRA 50MG TABLET since it may increase the risk of occurrence of osteonecrosis (segmental bone death due to impaired blood supply). KIDNEYINSTGRA 50MG TABLET should be taken with caution in patients with kidney problems such as mild, moderate/severe renal impairment. Consult your doctor before taking INSTGRA 50MG TABLET. LIVERINSTGRA 50MG TABLET should be used with caution in patients with liver problems such as mild to moderate hepatic impairment. Consult your doctor before taking INSTGRA 50MG TABLET. ALLERGYDo not take INSTGRA 50MG TABLET if you are allergic to Dolutegravir, and/or any other ingredients of this medicine. OTHERSBefore taking INSTGRA 50MG TABLET, inform your doctor if you: are suffering from advanced HIV infection and have weak immune system with prone to develop serious infections. Use in Pediatrics: INSTGRA 50MG TABLET is not recommended for use in children (aged below 6 years) and in children who weigh less than 14 kg and who are resistant to other medicines similar to INSTGRA 50MG TABLET. Consult your doctor before taking INSTGRA 50MG TABLET. Use in Geriatrics: INSTGRA 50MG TABLET should be used with caution in elderly patients (aged 65 years/ above). Consult your doctor before taking INSTGRA 50MG TABLET.
Drug Interactions
SA. Drug - Drug interactions: Before taking INSTGRA 50MG TABLET, inform your doctor if you are taking any of the following medicine: fampridine (used to manage multiple sclerosis) metformin (used to manage diabetes) antacids (used to manage indigestion and heartburn) calcium supplements, iron supplements, and multivitamins etravirine, efavirenz, fosamprenavir/ritonavir, nevirapine or tipranavir/ritonavir (used to manage HIV infection) rifampicin (used to manage tuberculosis and other bacterial infections) phenytoin, phenobarbital (used to manage epilepsy) oxcarbazepine, carbamazepine (manage epilepsy/bipolar disorder) St. John’s wort (herbal medicine used to manage depression) Overdosage: If you or anyone else accidentally take too much of INSTGRA 50MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms. SYNOPSIS Drug : Dolutegravir Pharmacological Category : Integrase inhibitor Therapeutic Indication : HIV infection Dosage Forms : Tablet MORE INFORMATION Keep INSTGRA 50MG TABLET out of reach of children Store INSTGRA 50MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
22 Dec 2022