Imatib 100mg Tablet 10'S
Key Information
Generic Name
Generic Name Imatinib 100 mg
Manufacturer
Cipla Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
IMATIB 100MG TABLET contains Imatinib which belongs to the group of medicines called Tyrosine Kinase Inhibitors. It is used in adults, children and adolescents to manage chronic myeloid leukaemia (CML) (a form of leukaemia in which certain abnormal white cells (named myeloid cells) start growing out of control) and philadelphia chromosome positive acute lymphoblastic leukaemia (Ph-positive ALL) (a form of leukaemia in which certain abnormal white cells (named lymphoblasts) start growing out of control). Also, it is used in adults only to manage myelodysplastic/myeloproliferative diseases (MDS/MPD) (a group of blood diseases in which some blood cells start growing out of control), hyper eosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL) (a blood diseases in which some blood cells (named eosinophils) start growing out of control), gastrointestinal stromal tumours (GIST) (cancer of the stomach and bowels) and dermatofibrosarcoma protuberans (DFSP) (cancer of the tissue beneath the skin in which some cells start growing out of control). Before taking IMATIB 100MG TABLET, inform your doctor if you have or ever had kidney, liver or heart problems, hepatitis B infection and thrombotic microangiopathy (symptoms include bruising, bleeding, fever, fatigue and confusion). IMATIB 100MG TABLET is generally not recommended for use in pregnant women unless advised by the doctor and it is not recommended for use in breastfeeding women. IMATIB 100MG TABLET should be used with caution in children, adolescents and elderly patients (aged 65 years and above). The most common
Uses
OF IMATIB 100MG TABLETManage adults, children and adolescents for: chronic myeloid leukaemia (CML) philadelphia chromosome positive acute lymphoblastic leukaemia (Ph-positive ALL) Manage adults for: myelodysplastic/myeloproliferative diseases (MDS/MPD) hyper-eosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL) gastrointestinal stromal tumors (GIST) dermatofibrosarcoma protuberans (DFSP)
How It Works
IMATIB 100MG TABLET is a protein-tyrosine kinase inhibitor. Tyrosine kinases are proteins which act as chemical messengers that are used by the cancer cells to signal each other for their growth, therefore this medicine works by blocking the enzyme which stops the cancer cells from growing.
Directions for Use
Take IMATIB 100MG TABLET as advised by your physician. Swallow the IMATIB 100MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking IMATIB 100MG TABLET are nausea, vomiting, diarrhea, headache, weight gain, loss of appetite, disturbed sense of taste, blurred vision and weakness. Consult your physician if any of the side effects worsen. USES OF IMATIB 100MG TABLETManage adults, children and adolescents for: chronic myeloid leukaemia (CML) philadelphia chromosome positive acute lymphoblastic leukaemia (Ph-positive ALL) Manage adults for: myelodysplastic/myeloproliferative diseases (MDS/MPD) hyper-eosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL) gastrointestinal stromal tumors (GIST) dermatofibrosarcoma protuberans (DFSP) HOW IMATIB 100MG TABLET WORKSIMATIB 100MG TABLET is a protein-tyrosine kinase inhibitor. Tyrosine kinases are proteins which act as chemical messengers that are used by the cancer cells to signal each other for their growth, therefore this medicine works by blocking the enzyme which stops the cancer cells from growing. DIRECTIONS FOR USETake IMATIB 100MG TABLET as advised by your physician. Swallow the IMATIB 100MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF IMATIB 100MG TABLETCOMMON headache or feeling tired nausea, vomiting, diarrhea or indigestion rash muscle cramps, joint, muscle or bone pain swelling such as round ankles or puffy eyes weight gain loss of appetite, weight loss or disturbed sense of taste feeling dizzy or weak insomnia conjunctivitis watery eyes, or blurred vision nose bleeds pain or swelling in the abdomen, flatulence, heartburn or constipation itching unusual hair loss or thinning numbness of the hands or feet mouth ulcers dry mouth, dry skin or dry eye decreased or increased skin sensitivity hot flushes, chills or night sweats RAREStop taking IMATIB 100MG TABLET and contact your doctor immediately if you experience any of the following side effects: rapid weight gain, severe fluid retention infection symptoms such as fever, severe chills, sore throat or mouth ulcers, low white blood cells unexpected bleeding or bruising sign of heart problems like chest pain or irregular heart rhythm sign of lung problems like cough, difficulty in breathing or painful breathing signs of low blood pressure like feeling light-headed, dizzy or fainting sign of liver problems like nausea, loss of appetite, dark-colored urine, yellow skin or eyes sign of skin problems like rash, red skin with blisters on the lips, eyes, skin or mouth, peeling skin, fever, raised red or purple skin patches, itching, burning sensation, a pustular eruption and sudden swelling and redness of the skin (cellulitis) sign of gastrointestinal disorders like severe abdominal pain, blood in vomit, stools or urine, black stools signs of kidney problems like severely decreased urine output and feeling thirsty signs of bowel problems like nausea with diarrhea and vomiting, abdominal pain or fever signs of nervous system problems like severe headache, weakness or paralysis of limbs or face, difficulty speaking, sudden loss of consciousness, bleeding or swelling in skull/brain signs of low levels of red blood cells like pale skin, feeling tired and breathlessness and having dark urine signs of raynaud’s syndrome like numb or cold toes and fingers signs of muscle problems like muscle spasms with a fever, red-brown urine, pain or weakness in your muscles eye pain or deterioration in vision, bleeding in the eyes pain in hips or difficulty walking difficulty in hearing signs of problems with ovaries or womb like pelvic pain with unexpected vaginal bleeding thrombotic microangiopathy (blood clots in small blood vessels)
Warnings & Precautions
& PRECAUTIONSPREGNANCYIMATIB 100MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Women who might become pregnant are advised to use effective contraceptive measures during management and for 15 days after ending the> management. Consult your doctor before taking IMATIB 100MG TABLET. BREASTFEEDINGIMATIB 100MG TABLET is not recommended for use during breastfeeding and for 15 days after ending the management as it may harm the baby. Consult your doctor before taking IMATIB 100MG TABLET. DRIVING AND USING MACHINESDo not drive or operate any machines if you experience dizziness, drowsiness or blurred vision after taking IMATIB 100MG TABLET. KIDNEYIMATIB 100MG TABLET should be used with caution in patients with kidney problem. Consult your doctor before taking IMATIB 100MG TABLET. LIVERIMATIB 100MG TABLET should be used with caution in patients with liver problems and hepatitis B infection. Consult your doctor before taking IMATIB 100MG TABLET. ALLERGYDo not take IMATIB 100MG TABLET if you are allergic to imatinib or any other ingredients of this medicine. HEART DISEASEIMATIB 100MG TABLET should be used with caution in patients with heart problem. Consult your doctor before taking IMATIB 100MG TABLET. OTHERSBefore taking IMATIB 100MG TABLET, inform your doctor if you have: thrombotic microangiopathy symptoms such as bruising, bleeding, fever, fatigue and confusion Use in pediatrics: IMATIB 100MG TABLET should be used with caution in children and adolescents. Consult your child’s doctor for advice. Use in geriatrics: IMATIB 100MG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking IMATIB 100MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking IMATIB 100MG TABLET, inform your doctor if you are taking any of the following medicines: medicines used to manage fever and pain (Ex. paracetamol) st. john’s wort (used to manage depression) medicines used to manage blood clots (Ex. clopidogrel) medicine used to manage thyroid (levothyroxine) Overdosage: If you or anyone else accidentally take too much of IMATIB 100MG TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Imatinib Pharmacological Category : Tyrosine kinase inhibitor Therapeutic Indication : Chronic myeloid leukaemia, Philadelphia chromosome positive acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases hyper eosinophilic syndrome or chronic eosinophilic leukaemia, Gastrointestinal stromal tumors, dermatofibrosarcoma protuberans Dosage Forms : Tablet, Capsule MORE INFORMATION Keep IMATIB 100MG TABLET out of reach of children Store IMATIB 100MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
23 Nov 2022