Gros 100mg Injection 1's
Key Information
Generic Name
Generic Name Paclitaxel 100 mg
Manufacturer
Emcure Pharmaceuticals Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT GROS 100MG INJECTIONGROS 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. GROS 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. GROS 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. GROS 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving GROS 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). GROS 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving GROS 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. GROS 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common
Uses
OF GROS 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals.
How It Works
GROS 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals.
Directions for Use
GROS 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
receiving GROS 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF GROS 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW GROS 100MG INJECTION WORKSGROS 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USEGROS 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF GROS 100MG INJECTIONCOMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction).
Warnings & Precautions
& PRECAUTIONSPREGNANCYGROS 100MG INJECTION is generally not recommended for use in pregnant women. Women with child-bearing potential should use effective contraception method while receiving GROS 100MG INJECTION which should be continued for next-6 months after completing the> management. Consult your doctor before receiving GROS 100MG INJECTION. BREASTFEEDINGGROS 100MG INJECTION is not recommended for use in breastfeeding women as it is not known whether the medicine pass through breast milk. Consult your doctor before receiving the medicine. DRIVING AND USING MACHINESDo not drive or use heavy machines if you feel dizzy/tired after receiving GROS 100MG INJECTION. ALCOHOLAvoid consumption of alcohol while receiving GROS 100MG INJECTION since it may cause harmful effects to the patient. KIDNEYGROS 100MG INJECTION should be used with caution in patient with chronic kidney disease. Consult your doctor before receiving GROS 100MG INJECTION. LIVERGROS 100MG INJECTION is not recommended for use in patients with severe hepatic impairment. It should be used with caution in patients with mild to moderate hepatic impairment. Consult your doctor before receiving the medicine. ALLERGYDo not receive GROS 100MG INJECTION if you are allergic to paclitaxel, polyoxyethylated castor oil and/or any other ingredients of this medicine. HEART DISEASEGROS 100MG INJECTION should be used with caution in patients with heart conduction problems, severe coronary artery disease, myocardial infarction and arrhythmias. Consult your doctor before receiving the medicine. OTHERSGROS 100MG INJECTION is not recommended for use if you: have too few white blood cells count have serious and uncontrolled infection. Before receiving GROS 100MG INJECTION, inform your doctor if you: have signs of bone marrow suppression such as fever, sever chills, sore throat and/or mouth ulcers had previous radiation to your chest have signs of mucositis such as sore/red mouth suffer from thrombocytopenia (low platelet count) suffer from acute infections (such as herpes zoster, chickenpox, herpes). Use in Pediatrics: GROS 100MG INJECTION is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before receiving the medicine. Use in Geriatrics: GROS 100MG INJECTION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving the medicine.
Drug Interactions
SA. Drug - Drug interactions: Before receiving GROS 100MG INJECTION, inform your doctor if you are taking any of the following medicine: erythromycin, rifampicin (medicines used to manage infections) ketoconazole (used for fungal infections) fluoxetine (used to stabilize mood) carbamazepine, phenytoin (used to manage seizures/epilepsy) gemfibrozil (used to lower blood lipid levels) cimetidine (used for heartburn/stomach ulcers) ritonavir, saquinavir, indinavir, nelfinavir, efavirenz, nevirapine (used to manage HIV and AIDS) clopidogrel (used to manage blood clots) verapamil, quinidine (used to manage irregular heart rhythms) diazepam (used to manage anxiety, muscle spasm, seizures) cyclosporine (used to manage rejection of transplanted organ) cisplatin (used for testicular cancer) cimetidine (used to manage gastroesophageal reflux disease) ranitidine (used for indigestion, gastroesophageal reflux disease and manage stomach ulcers) dexamethasone (used for inflammation, severe allergies) diphenhydramine (used to manage short term sleep problems). Overdosage: GROS 100MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms. SYNOPSIS Drug : Paclitaxel Pharmacological Category : Antineoplastic agents Therapeutic Indication : Ovarian cancer, Breast cancer, Kaposi sarcoma, Non-small cell lung cancer (NSCLC) Dosage Forms : Injection MORE INFORMATION Keep GROS 100MG INJECTION out of reach of children Do not store GROS 100MG INJECTION above 25°C
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
28 Oct 2022