Granicip Injection 3ml

Cancer Oncology (448)Rx required

Key Information

Generic Name

Generic Name Granisetron 3 mg

Manufacturer

Cipla Ltd

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT GRANICIP INJECTIONGRANICIP INJECTION contains a medicine Granisetron which belongs to a group of medicines called Anti-emetics. It is used to manage or manage nausea (feeling sick) and vomiting (being sick) caused by other medical managements such as chemotherapy or radiation management for cancer or by surgery. Before receiving GRANICIP INJECTION inform your doctor if you have heart disease, blockage in your stomach or intestines, or electrolyte abnormalities. GRANICIP INJECTION is not recommended for use in pregnant and breastfeeding women. Consult with your doctor before receiving it. GRANICIP INJECTION should not be given to children below 2 years of age. GRANICIP INJECTION can be used in elderly people (65 years and older).

Uses

OF GRANICIP INJECTIONPrevents or manages nausea and vomiting caused by, chemotherapy or radiotherapy for cancer surgery

How It Works

GRANICIP INJECTION acts by inhibiting a receptor called 5-HT3 receptor which is present both in the brain and gastrointestinal tract. This inhibition of 5-HT3 receptors in turn inhibits the stimulation of the vomiting centre, managing nausea and vomiting.

Directions for Use

GRANICIP INJECTION will be given as an injection into the veins (intravenous) by your doctor or nurse. Your doctor will give the right dose depending on your age, body weight and health condition.

Side Effects

receiving GRANICIP INJECTION are headache, constipation, problems sleeping (insomnia), and diarrhoea. Consult with your doctor if any of these worsen or doesn’t improve. USES OF GRANICIP INJECTIONPrevents or manages nausea and vomiting caused by, chemotherapy or radiotherapy for cancer surgery HOW GRANICIP INJECTION WORKSGRANICIP INJECTION acts by inhibiting a receptor called 5-HT3 receptor which is present both in the brain and gastrointestinal tract. This inhibition of 5-HT3 receptors in turn inhibits the stimulation of the vomiting centre, managing nausea and vomiting. DIRECTIONS FOR USEGRANICIP INJECTION will be given as an injection into the veins (intravenous) by your doctor or nurse. Your doctor will give the right dose depending on your age, body weight and health condition. SIDE EFFECTS OF GRANICIP INJECTIONCOMMON headache constipation problems sleeping (insomnia) changes in liver function tests (pain in the abdomen, nausea, vomiting, jaundice) diarrhoea RAREStop receiving GRANICIP INJECTION and inform your doctor immediately if you experience any of the following side effects: changes in the heartbeat, chest pain, irregular heartbeat and changes seen on ECG readings (electrical recordings of the heart) swelling of the hands, feet, ankles, face, lips and mouth or throat, which may cause difficulty in swallowing or breathing rash or itching fainting serotonin syndrome symptoms such as diarrhoea, nausea, vomiting, high temperature and blood pressure, excessive sweating and rapid heartbeat, agitation, confusion, hallucination, shivering, muscle shakes, jerks or stiffness, loss of coordination and restlessness

Warnings & Precautions

& PRECAUTIONSPREGNANCYGRANICIP INJECTION is not recommended for use in pregnant women. Consult your doctor before receiving it. BREASTFEEDINGGRANICIP INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving it. DRIVING AND USING MACHINESGRANICIP INJECTION is not likely to affect your ability to drive or use any tools or machines. ALLERGYDo not receive GRANICIP INJECTION if you are allergic (hypersensitive) to Granisetron or any other ingredients of this medicine. HEART DISEASEGRANICIP INJECTION should be used with caution in patients suffering from heart disease. Consult your doctor for advice before receiving this medicine. OTHERSBefore receiving GRANICIP INJECTION, inform your doctor if you have: blockage in the intestine (stomach-ache, wind, feeling or being sick, or difficulty passing stools) electrolyte abnormalities (potassium, sodium, or calcium) serotonin syndrome been or are being managed for cancer with a medicine that might cause damage to your heart Use in pediatrics: GRANICIP INJECTION is not recommended for use in children below 2 years of age. Consult with your child’s doctor before giving this to your child. Use in geriatrics: GRANICIP INJECTION can be used in elderly people (65 years and older). However, consult with your doctor before receiving.

Drug Interactions

SA. Drug - Drug interactions: Before receiving GRANICIP INJECTION, inform your doctor if you are taking any of the following medicines: other 5-HT3 receptor antagonist such as dolasetron or ondansetron (used to manage nausea and vomiting) diltiazem, amlodipine (medicines used to manage an irregular heartbeat) phenobarbital (used to manage epilepsy) ketoconazole (used to manage fungal infections) paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine, escitalopram (used to manage depression and/or anxiety) erythromycin (used to manage certain bacterial infections) Overdosage: GRANICIP INJECTION will be administered only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if there are any unusual symptoms such as headache. SYNOPSIS Drug : Granisetron Pharmacological Category : 5-HT3 Receptor Antagonist Therapeutic Indication : Nausea and vomiting caused by chemotherapy or radiotherapy Dosage Forms : Tablet, Syrup, Suspension, Injection MORE INFORMATION Keep GRANICIP INJECTION out of reach of children Store GRANICIP INJECTION at room temperature below 30°C

Article Information

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Written By

ity (HPRA). [Revised in June 2020]. [Accessed on 26th November 2022]. http://www.hpra.ie/img/uploaded/swedocuments/276485a0-e462-4d1d-b47b-1b3a00f59273.pdf 7. Medsafe. Granirex (Granisetron). [Revised in January 2022]. [Accessed on 26th November 2022]. https://www.medsafe.govt.nz/Profs/Datasheet/g/granirexinj.pdf 8. Atnahs Pharma UK Limited. Kytril (Granisetron). Pharmanovia. [Accessed on 26th November 2022]. https://pharmanovia.com/product/kytril/ 9. Drug Bank. Granisetron. [Accessed on 26th November 2022]. https://go.drugbank.com/drugs/DB00889 USEFUL DIAGNOSTIC TESTS Complete Blood Count AUTHOR DETAILS Written By Dr. Priyanka Goel

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

28 Nov 2022

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#cancer oncology (448)#generic name granisetron 3 mg