GRANDEM MD Tablet 10's
Key Information
Generic Name
Generic Name Granisetron 1 mg
Manufacturer
Aristo Pharmaceuticals Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
GRANDEM MD TABLET contains Granisetron which belongs to a group of medicines called Anti-emetics. It is used to manage nausea and vomiting caused by other medical managements such as chemotherapy or radiation management for cancer. Before taking GRANDEM MD TABLET inform your doctor if you have heart diseases, blockage in your stomach or intestines, electrolyte abnormalities, galactose intolerance, lactase deficiency or glucose-galactose malabsorption. GRANDEM MD TABLET is not recommended for use in pregnant and breast-feeding women. Consult with your doctor before taking. GRANDEM MD TABLET should not be used in children below 2 years of age. GRANDEM MD TABLET can be used in elderly people (65 years and above).
Uses
OF GRANDEM MD TABLET It is used to manage nausea and vomiting caused by other medical managements such as chemotherapy or radiation
How It Works
GRANDEM MD TABLET acts by inhibiting a receptor called 5-HT3 receptors present which present both in brain and gastrointestinal tract. This inhibition of 5-HT3 receptors in turn inhibits the stimulation of the vomiting centre, managing nausea and vomiting.
Directions for Use
Always take GRANDEM MD TABLET as directed by your physician. Swallow the medicine with a plenty of water and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your conditions.
Side Effects
these worsen or doesn’t improve. USES OF GRANDEM MD TABLET It is used to manage nausea and vomiting caused by other medical managements such as chemotherapy or radiation HOW GRANDEM MD TABLET WORKSGRANDEM MD TABLET acts by inhibiting a receptor called 5-HT3 receptors present which present both in brain and gastrointestinal tract. This inhibition of 5-HT3 receptors in turn inhibits the stimulation of the vomiting centre, managing nausea and vomiting. DIRECTIONS FOR USEAlways take GRANDEM MD TABLET as directed by your physician. Swallow the medicine with a plenty of water and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your conditions. SIDE EFFECTS OF GRANDEM MD TABLETCOMMON headache constipation problems sleeping changes in liver function tests (pain in abdomen, nausea, vomiting, jaundice) diarrhoea Stop taking GRANDEM MD TABLET and inform your doctor immediately if you experience any of the following side effects: changes in the heartbeat, chest pain, irregular heartbeat and changes seen on ECG readings (electrical recordings of the heart) swelling of the hands, feet, ankles, face, lips and mouth or throat, which may cause difficulty in swallowing or breathing rash or itching fainting serotonin syndrome symptoms such as diarrhoea, nausea, vomiting, high temperature and blood pressure, excessive sweating and rapid heartbeat, agitation, confusion, hallucination, shivering, muscles shakes, jerks or stiffness, loss of coordination and restlessness
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedGRANDEM MD TABLET is not recommended for use in pregnant women. Consult your doctor before taking it. BREASTFEEDINGContraindicatedGRANDEM MD TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINESUse with CautionGRANDEM MD TABLET should not affect your ability to drive or operate machinery. ALLERGYContraindicatedDo not take GRANDEM MD TABLET if you are allergic (hypersensitive) to Granisetron or any other ingredients of this medicine. HEART DISEASEUse with CautionGRANDEM MD TABLET should be used with caution in patients suffering from heart diseases. Consult your doctor for advice before taking GRANDEM MD TABLET. USE IN PEDIATRICSContraindicatedGRANDEM MD TABLET is not recommended for use in children below 2 years of age. Consult with your child’s doctor before giving this to your child. USE IN GERIATRICSUse with CautionGRANDEM MD TABLET can be used in elderly people (65 years and older). However, consult with your doctor before taking. OTHERSBefore taking GRANDEM MD TABLET, inform your doctor if you have: blockage in the intestine (stomach-ache, wind, feeling or being sick, or difficulty passing stools) electrolyte abnormalities (potassium, sodium, or calcium) serotonin syndrome been or are being managed for cancer with a medicine that might cause damage your heart lactose intolerance
Drug Interactions
SA. Drug-Drug interactions: Before taking GRANDEM MD TABLET, inform your doctor if you are taking any of the following medicines: other 5-HT3 receptor antagonist such as dolasetron or ondansetron (used to manage nausea and vomiting) diltiazem, amlodipine (medicines used to manage an irregular heartbeat) phenobarbital (used to manage epilepsy) ketoconazole (used to manage fungal infections) paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine, escitalopram (used to manage depression and/or anxiety) buprenorphine, tramadol (used to manage acute and chronic pain) Overdosage: If you or anyone else accidentally takes too much of GRANDEM MD TABLET, consult your doctor immediately. Symptoms of overdose includes mild headaches. SYNOPSIS Drug : Granisetron Pharmacological Category : 5-HT3 Receptor Antagonist Therapeutic Indication : Nausea and vomiting caused by chemotherapy or radiotherapy Dosage Forms : Tablet, Syrup, Suspension, Injection MORE INFORMATIONSTORAGE Keep GRANDEM MD TABLET out of reach from children Store GRANDEM MD TABLET at room temperature below 30°C
Frequently Asked Questions
Common questions and answers about GRANDEM MD Tablet 10's.
What is GRANDEM MD TABLET and why is it prescribed?
GRANDEM MD TABLET contains Granisetron which is used to manage nausea and vomiting caused by other medical managements such as chemotherapy or radiation management for cancer.
Does GRANDEM MD TABLET cause constipation?
Yes, GRANDEM MD TABLET may cause constipation in some individuals. Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Ask for your doctor’s advice if constipation doesn’t improve.
Can I stop taking GRANDEM MD TABLET when my symptoms are relieved?
No. Do not stop taking GRANDEM MD TABLET before the management is finished. If you stop taking GRANDEM MD TABLET, your symptoms may return. Ask for your doctor’s advice if you wish to stop taking this medicine.
Can I take GRANDEM MD TABLET during heart disease?
GRANDEM MD TABLET should be used with caution in patients suffering from heart disease. Consult your doctor for advice before taking GRANDEM MD TABLET.
What is the best time to take GRANDEM MD TABLET?
Always take GRANDEM MD TABLET as directed by your physician. GRANDEM MD TABLET can be taken with or without food. Your doctor will decide the correct dose and duration for you depending upon your conditions.
Article Information
Written By
ity (HPRA). [Revised in March 2021]. [Accessed on 26th November 2022] http://www.hpra.ie/img/uploaded/swedocuments/Licence_PA22657-003-003_23032021132538.pdf 7. Natco Pharma Ltd. Granisetron Tablets. Dailymed. [Revised in May 2022]. [Accessed on 26th November 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=df4b6775-4337-41e0-815a-b064d98c3fe1 8. Aspen Pharmacare. Granisetron. [Revised in January 2022] [Accessed on 26th November 2022] https://pi-pil-repository.sahpra.org.za/wp-content/uploads/2022/03/1.3.2_Aspen-Granisetron_27-January-2022_EPIL.pdf 9. Atnahs Pharma UK Limited. Kytril (Granisetron). Pharmanovia. [Accessed on 26th November 2022] https://pharmanovia.com/product/kytril/ 10. Drug Bank. Granisetron. [Accessed on 26th November 2022] https://go.drugbank.com/drugs/DB00889 USEFUL DIAGNOSTIC TESTS Complete Blood Count AUTHOR DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
22 Aug 2024