GLZ Plus Tablet 15'S
Key Information
Generic Name
Generic Name Gliclazide 80 mg+Metformin 500 mg
Manufacturer
Alembic Pharmaceuticals Ltd
Variant
15 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
GLZ PLUS TABLET is used in the management of diabetes mellitus when dietary measures, physical exercise, and weight loss alone are not sufficient to control blood glucose. It is a combination of Gliclazide and Metformin which belongs to the group of medicines called Antidiabetic agents. GLZ PLUS TABLET is not recommended for use if you have chronic obstructive pulmonary disease, kidney disease, or liver failure. The use of GLZ PLUS TABLET is not recommended for use in pregnant women. It is not known whether the medicine or its metabolites are excreted in breast milk. Hence consult your doctor before taking the medicine. GLZ PLUS TABLET is not recommended for use in children as safety and effectiveness have not been established. The most common
Uses
OF GLZ PLUS TABLET Used to manage type II diabetes mellitus
How It Works
GLZ PLUS TABLET effectively controls blood glucose levels, where Gliclazide works by increasing the amount of insulin by stimulating the pancreas and helps to control blood glucose levels. Metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body.
Directions for Use
Take GLZ PLUS TABLET, preferably just before meals, during meals, or as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition
Side Effects
the side effects worsen. USES OF GLZ PLUS TABLET Used to manage type II diabetes mellitus HOW GLZ PLUS TABLET WORKSGLZ PLUS TABLET effectively controls blood glucose levels, where Gliclazide works by increasing the amount of insulin by stimulating the pancreas and helps to control blood glucose levels. Metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body. DIRECTIONS FOR USE Take GLZ PLUS TABLET, preferably just before meals, during meals, or as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition SIDE EFFECTS OF GLZ PLUS TABLET Common side effects of GLZ PLUS TABLET: nausea diarrhea gastric pain constipation vomiting metallic taste in the mouth
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedThe use of GLZ PLUS TABLET is not recommended for use in pregnant women. BREASTFEEDINGConsult your doctorIt is not known whether GLZ PLUS TABLET or its metabolites are excreted in breast milk. Hence consult your doctor before taking the medicine. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machinery if you have increased sweating, a fast heartbeat, vision disorders or difficulty in concentration, dizziness, weakness, or blurred vision after taking GLZ PLUS TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking GLZ PLUS TABLET, as it may increase the risk of unwanted side effects. KIDNEYContraindicatedGLZ PLUS TABLET is not recommended for use if you have kidney disease. LIVERContraindicatedGLZ PLUS TABLET is not recommended for use if you have liver failure. ALLERGYContraindicatedDo not take GLZ PLUS TABLET if you are allergic to Gliclazide, Metformin, or any of the other ingredients of this medicine. LUNGSContraindicatedGLZ PLUS TABLET is not recommended for use if you have chronic obstructive pulmonary disease. HEART DISEASEContraindicatedGLZ PLUS TABLET is not recommended for use if you have coronary heart disease, cardiac failure, or peripheral vascular disease. USE IN PEDIATRICSContraindicatedGLZ PLUS TABLET is not recommended for use in children as safety and effectiveness have not been established. USE IN GERIATRICSUse with CautionGLZ PLUS TABLET should be used with caution only in elderly patients with normal kidney function. OTHERSGLZ PLUS TABLET is not recommended for use if you: have type 1 diabetes mellitus have severe ketosis and acidosis planned for surgery have severe trauma have severe infections
Drug Interactions
SA. Drug-Drug interactions: Before taking GLZ PLUS TABLET, inform your doctor if you are taking any of the following medicines, such as: Angiotensin enzyme inhibitors (Ex. captopril, enalapril) Antidiabetic agents (Ex. insulin, acarbose) Beta-blockers (Ex. metoprolol) Antifungal (Ex. Fluconazole) H2 blockers (Ex. cimetidine) Monoamine 2 oxidase inhibitors (Ex. selegiline) Sulphonamides (Ex. sulfasalazine) Nonsteroidal anti-inflammatory agents (Ex. ibuprofen) Estrogens or oral contraceptives (Ex. estradiol, levonorgestrel) Anticonvulsants (Ex. Phenytoin) Quinolones (Ex. ciprofloxacin) Overdosage: If you or anyone else accidentally took more of GLZ PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause low blood sugar (hypoglycemia), and symptoms include dizziness, lightheadedness, hunger, nervousness, shaky feelings, drowsiness, confusion, perspiration, and palpitations. SYNOPSIS Drug : Gliclazide, Metformin Pharmacological Category : Sulfonylureas, Biguanides Therapeutic Indication : Type II diabetes mellitus Dosage Forms : Tablet MORE INFORMATION
Frequently Asked Questions
Common questions and answers about GLZ Plus Tablet 15'S.
What is GLZ PLUS TABLET used for?
GLZ PLUS TABLET is used to manage type 2 diabetes mellitus in adults. This combination helps regulate blood sugar levels effectively in individuals whose blood sugar is not adequately controlled by diet, exercise, or a single diabetes medication. It helps reduce the risk of diabetes-related complications such as heart disease, nerve damage, or kidney issues.
How GLZ PLUS TABLET works?
GLZ PLUS TABLET contains a combination of two medicines namely, Gliclazide and metformin. Gliclazide stimulates the pancreas to release more insulin, a hormone that lowers blood sugar levels. It also improves the body’s response to insulin. Metformin decreases the amount of sugar produced by the liver and reduces sugar absorption in the intestines. It also enhances the body’s ability to use insulin more effectively, making it a comprehensive treatment for blood sugar control.
What is the best time to take GLZ PLUS TABLET?
It is usually recommended to take GLZ PLUS TABLET with meals to minimize the risk of gastrointestinal side effects such as nausea or upset stomach. Following your doctor’s instructions regarding the timing is essential, as they might tailor the dose to suit your lifestyle and blood sugar patterns.
How many doses of GLZ PLUS TABLET can be taken in a day?
The dosage depends on the individual’s medical condition, blood sugar levels, and response to treatment. Typically, it is taken once or twice daily with meals, but the exact dose should be determined by a doctor. Taking more than the prescribed dose can lead to hypoglycemia (low blood sugar), so it’s crucial to stick to the recommended schedule.
Can GLZ PLUS TABLET be used during pregnancy?
The combination of Gliclazide + Metformin is generally not recommended during pregnancy due to the potential risk of harming the unborn baby. Instead, insulin is preferred for controlling blood sugar levels in pregnant women with diabetes. If you are pregnant or planning to conceive, consult your doctor for a safe treatment plan.
Can GLZ PLUS TABLET control blood sugar levels?
Yes, this medicine is highly effective in controlling blood sugar levels in people with type 2 diabetes especially when diet, lifestyle changes and treatment with single agents does not yield optimum blood sugar control. However, its effectiveness also depends on maintaining a healthy lifestyle, including regular exercise and a balanced diet. Regular monitoring of blood sugar is essential to ensure the medication works optimally.
Who should not use GLZ PLUS TABLET?
GLZ PLUS TABLET is not suitable for individuals with severe kidney or liver disease, type 1 diabetes or diabetic ketoacidosis, known allergies to Gliclazide, metformin, or any other ingredients in the medicine, or a history of lactic acidosis. Therefore, always inform your doctor about any pre-existing conditions or medications you are taking to avoid adverse effects.
What are the common side effects of GLZ PLUS TABLET?
The most common side effects of GLZ PLUS TABLET include nausea, vomiting, diarrhea, stomach pain, dizziness, or low blood sugar (hypoglycemia. Consult your doctor if any of these side effects worsens.
Is GLZ PLUS TABLET safe?
Yes, GLZ PLUS TABLET is generally safe when taken as prescribed. However, regular monitoring of kidney and liver function is necessary, as prolonged use can affect these organs. Additionally, following the recommended dose and schedule minimizes the risk of side effects.
Can GLZ PLUS TABLET be taken on an empty stomach or before food?
No, it is best taken with food to reduce the risk of stomach upset and hypoglycemia. Food helps slow down the absorption of Gliclazide, preventing a sudden drop in blood sugar levels, which can cause dizziness or weakness.
Is GLZ PLUS TABLET safe for kidney patients?
GLZ PLUS TABLET is not suitable for individuals with severe kidney disease, as it can increase the risk of lactic acidosis, a potentially life-threatening condition. Mild to moderate kidney impairment requires dose adjustment and close monitoring. Always consult your doctor before starting or continuing this medication.
How long will it take for GLZ PLUS TABLET to control blood sugar levels?
GLZ PLUS TABLET begins to lower blood sugar within a few hours of taking a dose. However, achieving optimal blood sugar control may take a few weeks, depending on individual response and adherence to the prescribed regimen, diet, and exercise plan.
Can I stop taking GLZ PLUS TABLET once my blood sugar is controlled?
No, stopping the medication without your doctor’s advice can cause your blood sugar levels to rise again, leading to complications. Diabetes is a chronic condition requiring ongoing management. Your doctor may adjust the dose or switch medications based on your progress, but self-discontinuation is not recommended.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
20 Nov 2024