GLYPANTA D 5/10 Tablet 10's
Key Information
Generic Name
Generic Name Dapagliflozin 10 mg+Linagliptin 5 mg
Manufacturer
Lincoln Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
GLYPANTA D 5/10 TABLET is a combination of Dapagliflozin and Linagliptin, which belongs to the group of medicines called Antidiabetic agents. It is used for the management of patients with type 2 diabetes mellitus who are inadequately controlled on metformin monotherapy. Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused by inadequate production of a hormone called insulin (produced by the pancreas to metabolize glucose) in the body or by inadequate sensitivity of body cells to the actions of insulin. Before starting management with GLYPANTA D 5/10 TABLET, your doctor will assess your volume status and kidney function by conducting a blood test. GLYPANTA D 5/10 TABLET should be used with caution in patients with liver disease, heart failure, and low blood pressure. Consult your doctor before taking it. Inform your doctor before taking this medicine if you are pregnant, think you may be pregnant, or are planning to have a baby. GLYPANTA D 5/10 TABLET is not recommended for use by breastfeeding women as it is not known whether it may pass through breast milk. Consult your doctor for advice. The most common
Uses
OF GLYPANTA D 5/10 TABLETTo manage type II diabetes mellitus
How It Works
GLYPANTA D 5/10 TABLET effectively controls blood glucose levels, where dapagliflozin works by inhibiting sodium-glucose co-transporter 2 protein in the kidneys and managing the reabsorption of glucose from the blood into the kidneys. As a result, more glucose is excreted in urine, which helps lower blood glucose levels in the body. Linagliptin works by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme (a protein that helps to degrade incretin hormones) and thus increasing the concentrations of incretin hormones, stimulating the release of insulin in a glucose-dependent manner, decreasing the levels of glucagon, and reducing glucose production in the liver.
Directions for Use
Take GLYPANTA D 5/10 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.
Side Effects
taking GLYPANTA D 5/10 TABLET are hypoglycemia, vulvovaginitis, balanitis and related genital infections, urinary tract infections, dizziness, rash, and back pain. Consult your doctor if any of the side effects worsen. USES OF GLYPANTA D 5/10 TABLETTo manage type II diabetes mellitus HOW GLYPANTA D 5/10 TABLET WORKSGLYPANTA D 5/10 TABLET effectively controls blood glucose levels, where dapagliflozin works by inhibiting sodium-glucose co-transporter 2 protein in the kidneys and managing the reabsorption of glucose from the blood into the kidneys. As a result, more glucose is excreted in urine, which helps lower blood glucose levels in the body. Linagliptin works by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme (a protein that helps to degrade incretin hormones) and thus increasing the concentrations of incretin hormones, stimulating the release of insulin in a glucose-dependent manner, decreasing the levels of glucagon, and reducing glucose production in the liver. DIRECTIONS FOR USETake GLYPANTA D 5/10 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition. SIDE EFFECTS OF GLYPANTA D 5/10 TABLETCOMMON Hypoglycaemia vulvovaginitis, balanitis, and related genital infections urinary tract infection, dysuria, polyuria dizziness rash back pain UNCOMMON fungal infection volume depletion, thirst constipation, dry mouth nocturia vulvovaginal pruritus, pruritus genital weight loss RAREStop taking GLYPANTA D 5/10 TABLET and consult your doctor immediately if you experience any of the following side effects: signs and symptoms of diabetic ketoacidosis such as rapid weight loss, nausea, vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth, or a different odour to your urine or sweat signs and symptoms of necrotizing fasciitis of the perineum (Fournier’s Gangrene) include pain or tenderness, erythema, or swelling in the genital or perineal area, along with fever or malaise
Warnings & Precautions
& PRECAUTIONSPREGNANCYConsult your doctorInform your doctor before taking this medicine if you are pregnant, think you may be pregnant, or are planning to have a baby. BREASTFEEDINGContraindicatedGLYPANTA D 5/10 TABLET is not recommended for use by breastfeeding women as it is not known whether it may pass through breast milk. Consult your doctor for advice. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machinery if you feel dizzy after taking GLYPANTA D 5/10 TABLET. ALCOHOLConsult your doctorAvoid excessive consumption of alcohol while taking GLYPANTA D 5/10 TABLET, as it may increase the risk of lactic acidosis. KIDNEYConsult your doctorGLYPANTA D 5/10 TABLET is not recommended for use if you have severe kidney disease or are on dialysis. Inform your doctor before taking GLYPANTA D 5/10 TABLET if you have urinary tract infections or moderate kidney disease. LIVERUse with CautionGLYPANTA D 5/10 TABLET should be used with caution in patients with liver disease. Consult your doctor before taking it. ALLERGYContraindicatedGLYPANTA D 5/10 TABLET is not recommended for use if you are allergic to dapagliflozin, linagliptin, or any of the other ingredients of this medicine. HEART DISEASEUse with CautionGLYPANTA D 5/10 TABLET should be used with caution in patients with heart failure or low blood pressure. Consult your doctor before taking it. USE IN PEDIATRICSContraindicatedGLYPANTA D 5/10 TABLET is not recommended for use in children or adults under 18 years of age. Consult your doctor before taking it. USE IN GERIATRICSUse with CautionGLYPANTA D 5/10 TABLET should be used with caution with elderly patients. Consult your doctor before taking it. OTHERSBefore taking GLYPANTA D 5/10 TABLET, inform your doctor if you: have genital fungal infections have type 1 diabetes or have a condition called diabetic ketoacidosis have or have had a disease of the pancreas have headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, a fast heartbeat, sweating, and feeling jittery have a stuffy or runny nose and a sore throat have diabetic skin lesions
Drug Interactions
SA. Drug-drug interactions: Before taking GLYPANTA D 5/10 TABLET, inform your doctor if you are taking any of the following medicines, such as: insulin or a sulphonyl urea, Ex. glimepiride or glipizide (other medicines used to manage diabetes mellitus) diuretics (medicines that increase urine production) (Ex. furosemide, chlorothiazide) rifampin (a medicine used in the management of tuberculosis) digoxin (a medicine used in the management of heart failure) topiramate or other carbonic anhydrase inhibitors (Ex. zonisamide, acetazolamide, or dichlorphenamide) (medicines used in the management of fits and glaucoma) ranolazine (a medicine used to manage angina) vandetanib (a medicine used to manage thyroid cancer) dolutegravir (a medicine used to manage HIV infection) cimetidine (a medicine used to manage stomach problems) corticosteroid (generally used to manage inflammation) (Ex. beclomethasone dipropionate) Overdosage: If you or anyone else accidentally took more GLYPANTA D 5/10 TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Dapagliflozin and Linagliptin Pharmacological Category : Sodium-glucose co-transporter 2 inhibitors, DPP-4 inhibitors Therapeutic Indication : Type II Diabetes mellitus Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep GLYPANTA D 5/10 TABLET out of the sight and reach of children Store GLYPANTA D 5/10 TABLET below 30°C
Frequently Asked Questions
Common questions and answers about GLYPANTA D 5/10 Tablet 10's.
What are the side effects of GLYPANTA D 5/10 TABLET?
The most common side effects of taking GLYPANTA D 5/10 TABLET are hypoglycemia, vulvovaginitis, balanitis and related genital infections, urinary tract infection, dysuria, polyuria, dizziness, rash, and back pain. Consult your doctor if any of the side effects worsen.
How does GLYPANTA D 5/10 TABLET work?
GLYPANTA D 5/10 TABLET effectively controls blood glucose levels, where dapagliflozin works by inhibiting sodium-glucose co-transporter 2 protein in the kidneys and managing the reabsorption of glucose from the blood into the kidneys. As a result, more glucose is excreted in urine, which helps lower blood glucose levels in the body. Linagliptin works by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme (a protein that helps to degrade incretin hormones) and thus increasing the concentrations of incretin hormones, stimulating the release of insulin in a glucose-dependent manner, decreasing the levels of glucagon, and reducing glucose production in the liver.
Is GLYPANTA D 5/10 TABLET safe during pregnancy?
There is no information on the use of GLYPANTA D 5/10 TABLET during pregnancy. Inform your doctor if you are pregnant or planning to be pregnant before taking it.
What precautions must be taken while using GLYPANTA D 5/10 TABLET?
GLYPANTA D 5/10 TABLET should be used with caution in patients with liver disease, urinary tract infections or moderate kidney disease, heart failure or low blood pressure, genital fungal infections, type 1 diabetes, a condition called diabetic ketoacidosis, a disease of the pancreas, a headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, a fast heartbeat, sweating, and feeling jittery, a stuffy or runny nose and a sore throat, or have diabetic skin lesions. Consult your doctor before taking GLYPANTA D 5/10 TABLET.
What if I forget to take GLYPANTA D 5/10 TABLET?
If you miss a dose of GLYPANTA D 5/10 TABLET, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Is GLYPANTA D 5/10 TABLET safe for kidneys?
GLYPANTA D 5/10 TABLET is not recommended for use if you have severe kidney disease or are on dialysis. Inform your doctor before taking GLYPANTA D 5/10 TABLET if you have urinary tract infections or moderate kidney disease.
What is GLYPANTA D 5/10 TABLET used for?
GLYPANTA D 5/10 TABLET is used for the management of patients with type 2 diabetes mellitus who are inadequately controlled on metformin alone.
What should I avoid while taking GLYPANTA D 5/10 TABLET?
Avoid excessive consumption of alcohol while taking GLYPANTA D 5/10 TABLET, as it may increase the risk of lactic acidosis.
Who should avoid taking GLYPANTA D 5/10 TABLET?
GLYPANTA D 5/10 TABLET is not recommended for use if you have severe kidney disease or are on dialysis, allergic to dapagliflozin, or linagliptin.
Can GLYPANTA D 5/10 TABLET be used in kids?
GLYPANTA D 5/10 TABLET is not recommended for use in children or adults under 18 years of age. Consult your doctor before taking it.
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
11 Sep 2024