GLUXIT S 10/50 Tablet 10's
Key Information
Generic Name
Generic Name Dapagliflozin 10 mg+Sitagliptin 50 mg
Manufacturer
Eris Lifesciences Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
GLUXIT S 10/50 TABLET is used to manage type II diabetes mellitus which is inadequately controlled on metformin monotherapy. It is a combination of Dapagliflozin and Sitagliptin which belongs to the group of medicines called Antidiabetic agents. It effectively controls blood sugar levels where dapagliflozin inhibits SGLT2, increasing urinary glucose excretion and reducing blood levels of glucose and Sitagliptin inhibits DPP-4, increases glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin synthesis and decreased glucagon release. GLUXIT S 10/50 TABLET is not recommended for use in patients having severe kidney problems or those on dialysis. Before taking the medicine, inform your doctor if you have inflammation of the pancreas, gallstones, alcohol dependence, or very high levels of triglycerides in the blood or any heart, kidney or liver problems. It should be used in pregnant women only if con
Uses
OF GLUXIT S 10/50 TABLET Used to manage type II diabetes mellitus (which is inadequately controlled on metformin monotherapy)
How It Works
GLUXIT S 10/50 TABLET effectively controls blood sugar levels where Dapagliflozin inhibits SGLT2, increasing urinary glucose excretion and reducing blood levels of glucose and Sitagliptin inhibits DPP-4, increases glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin synthesis and decreased glucagon release.
Directions for Use
Take GLUXIT S 10/50 TABLET as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine It can be taken with or without food Your doctor will decide the correct dose and duration of GLUXIT S 10/50 TABLET therapy depending on your age, body weight and disease condition.
Side Effects
the side effects worsen or persist for a longer period of time. USES OF GLUXIT S 10/50 TABLET Used to manage type II diabetes mellitus (which is inadequately controlled on metformin monotherapy) HOW GLUXIT S 10/50 TABLET WORKSGLUXIT S 10/50 TABLET effectively controls blood sugar levels where Dapagliflozin inhibits SGLT2, increasing urinary glucose excretion and reducing blood levels of glucose and Sitagliptin inhibits DPP-4, increases glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin synthesis and decreased glucagon release. DIRECTIONS FOR USE Take GLUXIT S 10/50 TABLET as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine It can be taken with or without food Your doctor will decide the correct dose and duration of GLUXIT S 10/50 TABLET therapy depending on your age, body weight and disease condition. SIDE EFFECTS OF GLUXIT S 10/50 TABLETCommon Side Effects of GLUXIT S 10/50 TABLET: flatulence, constipation, stomach pain, diarrhea swelling of hands or legs headache, dizziness stuffy or runny nose, sore throat passing urine more often dry mouth Stop taking GLUXIT S 10/50 TABLET and contact your physician immediately if you experience any of the following side effects: inflamed pancreas (severe and persistent stomach pain that might reach through the back with or without nausea and vomiting) serious allergic reaction (rash, hives, blisters on the skin or peeling skin and swelling of the lips, tongue, face and throat that may cause difficulty in breathing or swallowing) diabetic ketoacidosis (increased levels of ketone bodies in urine or blood, nausea or vomiting, stomach ache, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to breathe, a sweet or metallic taste in the mouth or a different odor in urine or sweat, rapid weight loss) urinary tract infection (fever, chills, burning sensation when passing urine, pain in the back or side, blood in urine) low blood sugar levels (shaking, sweating, feeling very anxious, fast heartbeat, feeling hungry, headache, change in vision, and a change in mood or feeling confused)
Warnings & Precautions
& PRECAUTIONSPREGNANCYConsult your doctorIf you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. BREASTFEEDINGConsult your doctorIt is not known if this medicine passes into breast milk. You should not take this medicine if you are breast-feeding or plan to breast-feed. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you feel dizzy or sleepy after taking GLUXIT S 10/50 TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking GLUXIT S 10/50 TABLET as it may increase the chance of diabetic ketoacidosis. KIDNEYUse with CautionGLUXIT S 10/50 TABLET can be used with caution in patients who had or have any kidney problems. LIVERUse with CautionGLUXIT S 10/50 TABLET can be used with caution in patients with severe liver impairment. ALLERGYContraindicatedDo not take GLUXIT S 10/50 TABLET if you are allergic to Dapagliflozin, Sitagliptin or any other ingredients of this medicine. HEART DISEASEUse with CautionGLUXIT S 10/50 TABLET can be used with caution in patients who have heart failure. USE IN PEDIATRICSConsult your doctorSafety and effectiveness of GLUXIT S 10/50 TABLET in children and adolescents (under 18 years of age) have not been established. USE IN GERIATRICSConsult your doctorNo dose adjustment is required for elderly patients. OTHERSGLUXIT S 10/50 TABLET is not recommended for use if you have: type I diabetes mellitus diabetic ketoacidosis Before taking GLUXIT S 10/50 TABLET inform your doctor if you: have inflammation of the pancreas have gallstones have very high levels of triglycerides in the blood are fasting are dehydrated
Drug Interactions
SA. Drug-Drug interactions: Before taking GLUXIT S 10/50 TABLET, inform your doctor if you are taking any of the following medicines: Anti-fungal (Ex. ketoconazole, itraconazole) Anti-viral agents (Ex. Ritonavir) Antibiotics (Ex. Clarithromycin) Immunosuppressants (Ex. Ciclosporin) Cardiac glycosides (Ex. Digoxin) Diuretics (Ex. hydrochlorothiazide, furosemide) Anti-diabetics (Ex. metformin, insulin, glimepiride) Overdosage: If you or anyone else accidentally takes too much of GLUXIT S 10/50 TABLET, consult your doctor or visit a nearby hospital immediately. SYNOPSIS Drug : Dapagliflozin, Sitagliptin Pharmacological Category : Sodium-Glucose Cotransporter 2 (SGLT2) inhibitor, Dipeptidyl Peptidase 4 (DPP-4) inhibitor Therapeutic Indication : Type II diabetes mellitus Dosage Forms : Tablet
Frequently Asked Questions
Common questions and answers about GLUXIT S 10/50 Tablet 10's.
What is GLUXIT S 10/50 TABLET and why it is prescribed?
GLUXIT S 10/50 TABLET is a combination of Dapagliflozin and Sitagliptin which belongs to the group of medicines called Antidiabetic agents. It is used to manage type II diabetes mellitus which is inadequately controlled on metformin monotherapy.
Does GLUXIT S 10/50 TABLET cause weight loss?
Yes, GLUXIT S 10/50 TABLET may cause weight loss in some individuals. To avoid weight loss, follow a healthy diet and regular physical activity as advised by your physician.
Can GLUXIT S 10/50 TABLET be taken along with insulin?
Taking GLUXIT S 10/50 TABLET along with insulin might increase the chance of hypoglycemia.
How does GLUXIT S 10/50 TABLET work?
GLUXIT S 10/50 TABLET effectively controls blood sugar levels where dapagliflozin inhibits SGLT2, increasing urinary glucose excretion and reducing blood levels of glucose and Sitagliptin inhibits DPP-4, increases glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), resulting in increased insulin synthesis and decreased glucagon release.
Is GLUXIT S 10/50 TABLET safe to use in patients with kidney problems?
GLUXIT S 10/50 TABLET can be used with caution in patients who had or have any kidney problems. Your doctor may monitor your kidney function test before and during management with this medicine to manage the risk of any unusual effects.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
20 Nov 2024