Glioz 20mg Capsule 5'S

Cancer Oncology (448)Rx required

Key Information

Generic Name

Generic Name Temozolomide 20 mg

Manufacturer

Dr. Reddy's Laboratories Ltd

Variant

5 Capsule(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT GLIOZ 20MG CAPSULEGLIOZ 20MG CAPSULE contains Temozolomide, which belongs to the group of medicines called Antineoplastic agents. It is used for specific forms of brain tumours in adults with newly diagnosed glioblastoma multiforme, which is used first together with radiotherapy as a concomitant phase of therapy and then used alone as a monotherapy. It is also used in children (above 3 years) and adults to manage malignant gliomas, such as glioblastoma multiforme or anaplastic astrocytoma, if they return or get worse after standard management. Glioblastoma multiforme is an aggressive type of cancer that affects the brain or spinal cord and is generally characterized by symptoms such as headache, nausea, drowsiness, blurred vision, personality changes, and seizures. Along with this management, your doctor might advise you to take liver function tests to assess the hepatotoxicity and function of your liver. Before taking GLIOZ 20MG CAPSULE, inform your doctor if you have or ever had a hepatitis B infection (serious liver infection). GLIOZ 20MG CAPSULE is not recommended for use if you have certain kinds of blood cells that are severely reduced, such as white blood cells and platelet count. GLIOZ 20MG CAPSULE should be used with caution during pregnancy only if it is clearly necessary and not recommended for use in breastfeeding women. It is not recommended for use in children below 3 years of age and should be used with caution in children and adolescents (from 3 to 18 years of age). Consult your doctor before taking GLIOZ 20MG CAPSULE. The most common

Uses

OF GLIOZ 20MG CAPSULEIt is used for: Specific forms of brain tumours in newly diagnosed glioblastoma multiforme (in adults) Malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma (in adults and children)

How It Works

GLIOZ 20MG CAPSULE works by damaging the genetic material (DNA and RNA) of the cancer cells in

Directions for Use

Take GLIOZ 20MG CAPSULE as advised by your physician. Swallow GLIOZ 20MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects

taking GLIOZ 20MG CAPSULE are loss of appetite, difficulty while speaking, headache, vomiting, nausea, diarrhea, and constipation. Consult and inform your doctor if any of these symptoms get worse. USES OF GLIOZ 20MG CAPSULEIt is used for: Specific forms of brain tumours in newly diagnosed glioblastoma multiforme (in adults) Malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma (in adults and children) HOW GLIOZ 20MG CAPSULE WORKSGLIOZ 20MG CAPSULE works by damaging the genetic material (DNA and RNA) of the cancer cells inside the brain cells and works against the cell growth and multiplication. DIRECTIONS FOR USETake GLIOZ 20MG CAPSULE as advised by your physician. Swallow GLIOZ 20MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF GLIOZ 20MG CAPSULECOMMON Loss of appetite Difficulty while speaking Headache Vomiting, nausea Diarrhea Constipation Rash Hair loss Tiredness Infections Feeling sick, extreme tiredness, loss of appetite (signs of neutropenia) Fever, cough, runny nose (signs of lymphopenia) Prolonged cuts, bleeding from gums, blood in urine (signs of thrombocytopenia) Allergic reactions Memory impairment Depression, anxiety, confusion, sleeplessness Difficulty concentrating Dizziness Visual disturbances Deafness, ringing in the ears, earache Blood clot in the lung or legs High blood pressure Shortness of breath Bronchitis Cough and cold Inflammation of sinuses Stomach or abdominal pain Dry skin, itching Muscle damage, muscle aches and pain, muscle weakness Joint and back pain Frequent urination Fever Flu-like symptoms such as chills, cough, fever, and muscle aches Pain Fluid retention Weight gain or loss Radiation injury such as weakness, hair loss, and bloody vomit UNCOMMON New or reactivated cytomegalovirus infections such as chickenpox, herpes simplex Signs of reactivated hepatitis B virus infections such as abdominal pain, dark urine, fever, and joint pain Secondary cancers, including leukemia (blood cancer) Reduced blood cell counts, such as pancytopenia Red spots under the skin Signs of diabetes insipidus Piles Dry mouth Blisters on body or in mouth Skin peeling, skin eruption, painful reddening of the skin, severe rash with skin swelling Increased sensitivity to sunlight Urticaria (red, itchy skin) Increased sweating Change in skin colour Vaginal bleeding or irritation Absent or heavy menstrual periods Breast pain Sexual impotence Shivering Stop taking GLIOZ 20MG CAPSULE and contact your doctor if you experience any of the following side effects: Signs of a severe allergic (hypersensitive) reaction such as itchy red skin, wheezing, or other breathing difficulty Uncontrolled bleeding Seizures (fits) Fever and symptoms of infections such as cough, chills, sweat Chills Severe headache

Warnings & Precautions

& PRECAUTIONSPREGNANCYMonitoring requiredGLIOZ 20MG CAPSULE should be used in pregnant women only if it is clearly necessary. Women with childbearing potential should use effective contraceptive precautions, which should be continued for at least 6 months following the completion of> management. Consult your doctor before taking GLIOZ 20MG CAPSULE. BREASTFEEDINGContraindicatedGLIOZ 20MG CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking GLIOZ 20MG CAPSULE. DRIVING AND USING MACHINESContraindicatedGLIOZ 20MG CAPSULE may cause tiredness or sleepiness. If you experience any such effects, avoid driving and using machines. Consult your doctor before taking GLIOZ 20MG CAPSULE. KIDNEYUse with CautionGLIOZ 20MG CAPSULE should be used with caution in patients with kidney problems such as severe renal impairment. Consult your doctor for advice before taking GLIOZ 20MG CAPSULE. LIVERUse with CautionGLIOZ 20MG CAPSULE should be used with caution in patients with mild, moderate, and severe hepatic impairment. Consult your doctor for advice before taking GLIOZ 20MG CAPSULE. ALLERGYContraindicatedDo not take GLIOZ 20MG CAPSULE if you are allergic to Temozolomide or any of the other ingredients of this medicine. LUNGSUse with CautionGLIOZ 20MG CAPSULE should be used with caution in patients with lung disease such as pneumocystis jirovecii pneumonia (serious fungal infection of lungs). Consult your doctor before taking GLIOZ 20MG CAPSULE. USE IN PEDIATRICSContraindicatedGLIOZ 20MG CAPSULE is not recommended for use in children below 3 years of age. There is limited information in patients over 3 years of age who have taken GLIOZ 20MG CAPSULE. Consult your doctor before taking GLIOZ 20MG CAPSULE. USE IN GERIATRICSUse with CautionGLIOZ 20MG CAPSULE should be used with caution in elderly patients (aged 70 years or above). Consult your doctor before taking GLIOZ 20MG CAPSULE. OTHERSGLIOZ 20MG CAPSULE is not recommended for use if you: Have certain kinds of blood cells that are severely reduced, such as white blood cells and platelet count Before taking GLIOZ 20MG CAPSULE, inform your doctor if you: Have signs of anemia (low red blood cell count) Have signs of low platelet count Have a risk of other changes in blood cells, such as leukemia (blood cancer)

Drug Interactions

SA. Drug-Drug Interactions: Before taking GLIOZ 20MG CAPSULE, inform your doctor if you are taking any of the following medicines: Dacarbazine (used for cancer of the lymph system and malignant melanoma) Overdosage: If you or anyone else accidentally takes too much of GLIOZ 20MG CAPSULE, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Temozolomide Pharmacological Category : Antineoplastic agents Therapeutic Indication : Glioblastoma multiforme, Anaplastic astrocytoma Dosage Forms : Capsule, Tablet, Injection MORE INFORMATIONSTORAGE Keep the medicine out of reach of children Store GLIOZ 20MG CAPSULE at room temperature

Frequently Asked Questions

Common questions and answers about Glioz 20mg Capsule 5'S.

Q

What GLIOZ 20MG CAPSULE is used for?

A

GLIOZ 20MG CAPSULE is used for specific forms of brain tumours in adults with newly diagnosed glioblastoma multiforme, which is used first together with radiotherapy as a concomitant phase of therapy and then used alone as a monotherapy. It is also used in children (above 3 years) and adults to manage malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, if they return or get worse after standard management.

Q

How should GLIOZ 20MG CAPSULE be taken?

A

Take GLIOZ 20MG CAPSULE as advised by your physician. Swallow GLIOZ 20MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q

What are the side effects of GLIOZ 20MG CAPSULE?

A

The most common symptoms of taking GLIOZ 20MG CAPSULE are loss of appetite, difficulty while speaking, headache, vomiting, nausea, diarrhea, and constipation. Consult and inform your doctor if any of these symptoms get worse.

Q

What happens if you forget to take GLIOZ 20MG CAPSULE?

A

If you forget to take GLIOZ 20MG CAPSULE at the usual time, take your dose as soon as possible and then continue with your medication at the usual times. Avoid taking a double dose to make up for forgotten individual doses. Consult and inform your doctor before taking GLIOZ 20MG CAPSULE if you have queries on the missed dose.

Q

Is GLIOZ 20MG CAPSULE safe to use in children?

A

GLIOZ 20MG CAPSULE is not recommended for use in children below 3 years of age. There is limited information in patients over 3 years of age who have taken GLIOZ 20MG CAPSULE. Consult your doctor before taking GLIOZ 20MG CAPSULE.

Q

How does GLIOZ 20MG CAPSULE work?

A

GLIOZ 20MG CAPSULE works by damaging the genetic material (DNA and RNA) of the cancer cells inside the brain cells and works against cell growth and multiplication.

Q

Is GLIOZ 20MG CAPSULE safe during pregnancy?

A

GLIOZ 20MG CAPSULE should be used in pregnant women only if it is clearly necessary. Women with childbearing potential should use effective contraceptive precautions, which should be continued for at least 6 months following the completion of> management. Consult your doctor before taking GLIOZ 20MG CAPSULE.

Q

Who should not take GLIOZ 20MG CAPSULE?

A

GLIOZ 20MG CAPSULE is not recommended for use if you have certain kinds of blood cells that are severely reduced, such as white blood cells and platelet count, or if you are allergic to temozolomide or any of the other ingredients of this medicine.

Q

What precautions must be taken while using GLIOZ 20MG CAPSULE?

A

GLIOZ 20MG CAPSULE should be used with caution in patients with kidney problems such as severe renal impairment, mild, moderate, and severe hepatic impairment, lung disease such as pneumocystis jirovecii pneumonia (serious fungal infection of lungs), signs of anemia (low red blood cell count), signs of low platelet count, or have a risk of other changes in blood cells such as leukemia (blood cancer). Consult your doctor for advice before taking GLIOZ 20MG CAPSULE.

Q

When should I stop taking GLIOZ 20MG CAPSULE?

A

Stop taking GLIOZ 20MG CAPSULE and contact your doctor if you experience any of the following side effects, such as signs of a severe allergic reaction such as itchy red skin, wheezing or other breathing difficulty, uncontrolled bleeding, seizures (fits), fever, and symptoms of infections such as cough, chills, sweat, chills, and severe headache.

Article Information

DW

Written By

DETAILS Written By Dr. N. Sai Swaroop

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

17 Jul 2024

Tags

#cancer oncology (448)#generic name temozolomide 20 mg