GLIDUM MF 2 Tablet 10's
Key Information
Generic Name
Generic Name Glimepiride 2 mg+Metformin 500 mg
Manufacturer
Knoll Healthcare Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
GLIDUM MF 2 TABLET is used to manage type 2 diabetes mellitus when diet, exercise and the single agent does not result in adequate glycemic control. It is a combination of Glimepiride and Metformin which belongs to a group of medicines called Antidiabetic agents. Glimepiride lowers blood sugar by causing the pancreas to produce more insulin and helps the body to use insulin efficiently. Metformin reduces the total amount of sugar released into the blood by the liver. Along management with GLIDUM MF 2 TABLET follow regular exercise and diet plan as advised by your doctor to achieve better results. Before taking GLIDUM MF 2 TABLET inform your doctor if you have type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney disease, acute heart problems. Inform your doctor if you are pregnant or breastfeeding. It is not suitable for use in children and adolescents under 18 years of age. Avoid consumption of alcohol during management with GLIDUM MF 2 TABLET as it may increase or decrease the blood sugar lowering action of GLIDUM MF 2 TABLET and increases the risk of lactic acidosis. The most common
Uses
OF GLIDUM MF 2 TABLET Used to manage type 2 diabetes mellitus (when diet, exercise and the single agent does not result in adequate glycemic control)
How It Works
GLIDUM MF 2 TABLET controls blood glucose levels, where Glimepiride works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestine, and increasing the body's sensitivity to insulin.
Directions for Use
Take GLIDUM MF 2 TABLET as advised by your physician Swallow GLIDUM MF 2 TABLET with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition Do not stop taking GLIDUM MF 2 TABLET without informing your doctor.
Side Effects
taking GLIDUM MF 2 TABLET are taste disturbance, diarrhea or stomach ache. Contact your doctor if any of the symptoms worsen. USES OF GLIDUM MF 2 TABLET Used to manage type 2 diabetes mellitus (when diet, exercise and the single agent does not result in adequate glycemic control) HOW GLIDUM MF 2 TABLET WORKSGLIDUM MF 2 TABLET controls blood glucose levels, where Glimepiride works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestine, and increasing the body's sensitivity to insulin. DIRECTIONS FOR USE Take GLIDUM MF 2 TABLET as advised by your physician Swallow GLIDUM MF 2 TABLET with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition Do not stop taking GLIDUM MF 2 TABLET without informing your doctor. SIDE EFFECTS OF GLIDUM MF 2 TABLETCommon side effects of GLIDUM MF 2 TABLET: taste disturbance diarrhea stomach pain loss of appetite Stop taking GLIDUM MF 2 TABLET and contact your doctor immediately if you experience any of the following side effects: lactic acidosis inflammation of the liver which may result in jaundice (yellowing of skin or eyes) severe allergic reactions (such as skin rash, hives, and increased sensitivity to sun, inflammation of blood vessels which may develop into serious reactions with difficulty in breathing, fall in blood pressure and sometimes progressing to shock) severe low blood sugar levels
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedGLIDUM MF 2 TABLET should not be taken during pregnancy. Consult your doctor before taking GLIDUM MF 2 TABLET if you are planning to become pregnant. BREASTFEEDINGContraindicatedGLIDUM MF 2 TABLET should not be taken during breastfeeding as it may pass through breast milk. DRIVING AND USING MACHINESUse with CautionDo not drive or handle any machines if you experience low or high blood sugar levels (symptoms include dizziness, tiredness, shaking or trembling) or if you develop visual problems due to altered blood sugar levels. ALCOHOLConsult your doctorAvoid consumption of alcohol during management with GLIDUM MF 2 TABLET as it may increase or decrease the blood sugar lowering action of GLIDUM MF 2 TABLET and increases the risk of lactic acidosis. KIDNEYConsult your doctorGLIDUM MF 2 TABLET is not recommended for use in patients with severe kidney disease and it should be used with caution in patients with kidney disease and your dose will be adjusted if needed depending upon kidney function. LIVERConsult your doctorGLIDUM MF 2 TABLET is not recommended if you have severe liver disease and it should be used with caution in patients with liver disease and your dose will be adjusted if needed depending upon liver function. ALLERGYContraindicatedDo not take GLIDUM MF 2 TABLET if you are allergic (hypersensitive) to Glimepiride or Metformin or other sulfonylureas (such as glipizide, glibenclamide) or sulfonamides (such as sulfamethoxazole). HEART DISEASEContraindicatedGLIDUM MF 2 TABLET is not recommended for use in patients with acute heart problems or recently had a heart attack or have severe circulatory problems or breathing difficulties (signs of heart failure). USE IN PEDIATRICSContraindicatedGLIDUM MF 2 TABLET is not recommended for use in children and adolescents (under 18 years of age). USE IN GERIATRICSConsult your doctorGLIDUM MF 2 TABLET is not recommended for use in elderly patients (aged 75 years or above) and it should be used with caution in elderly patients (aged 65 years or above), especially in patients with impaired kidney function. Your doctor may assess your kidney function more frequently during management with GLIDUM MF 2 TABLET. OTHERSGLIDUM MF 2 TABLET is not recommended for use, if you have: type 1 diabetes mellitus diabetic ketoacidosis uncontrolled diabetes or ketoacidosis dehydration severe infection Before taking GLIDUM MF 2 TABLET inform your doctor if you: are recovering from injury, operation, infections with fever, or from other forms of stress have glucose-6-phosphate dehydrogenase (G6PD) deficiency have various factors which could increase the risk of low blood sugar levels (such as undernourishment, irregular mealtime, missed or delayed meal or period of fasting, change in diet, hormone-induced disorders)
Drug Interactions
SA. Drug-Drug interactions: Before taking GLIDUM MF 2 TABLET inform to your doctor, if you are taking any of these medicines: Sulphonylureas (Ex. glibenclamide, insulin) Anabolics Anticoagulants (Ex. Warfarin) Anticonvulsants (Ex. Fenfluramine, Phenytoin) NSAIDs (Ex. Phenylbutazone, azopropazone, oxyphenbutazone) Class 1a anti-arrhythmic agent (Ex. Disopyramide) Fibrates (Ex. fenofibrate, nicotinic acid, colesevelam) Angiotensin-converting enzyme (Ex. captopril, lisinopril) Diuretics (Ex. furosemide, chlorthalidone, hydrochlorothiazide or diazoxide) Monoamine oxidase inhibitors (Ex. isocarboxazid, selegiline and chlorpromazine) Antigout agents (Ex. Allopurinol, probenecid, sulfinpyrazone) Alkylating agents (Ex. Cyclophosphamide, ifosfamide, trofosfamide) Tetracyclines (Ex. minocycline, doxycycline, chloramphenicol, fluconazole, miconazole Quinolones (Ex. moxifloxacin, ciprofloxacin, clarithromycin, rifampicin Tritoqualine, glucocorticoids (Ex. beclomethasone, hydrocortisone) Hemorrheologic agents (Ex. Pentoxifylline) Sulfonamides (Ex. sulfamethoxazole) Androstane class (Ex. testosterone) Natural or synthetic (Ex. oestrogens, progestogens) Sympatholytics (Ex. clonidine, methyldopa) Hormones (Ex. Levothyroxine) Adrenaline and sympathomimetics (Ex. phenylephrine, norepinephrine) Laxatives (Ex. bisacodyl) Antidiabetics (Ex. Glucagon) Barbiturates (Ex. pentobarbital, amobarbital) Carbonic anhydrase inhibitors (Ex. Acetazolamide) Overdosage: If you or anyone else takes too much of GLIDUM MF 2 TABLET, contact your doctor immediately or go to a nearest hospital straight away. Overdosage symptoms of GLIDUM MF 2 TABLET includes risk of low blood sugar levels. Symptoms of lactic acidosis include vomiting, bellyache with muscle cramps, general feeling of not being well with severe tiredness, reduced body temperature, low heartbeat, and difficulty in breathing. SYNOPSIS Drug : Glimepiride, Metformin Pharmacological Category : Sulfonylureas, Biguanides Therapeutic Indication : Type II diabetes mellitus Dosage Forms : Tablet MORE INFORMATION
Frequently Asked Questions
Common questions and answers about GLIDUM MF 2 Tablet 10's.
What is GLIDUM MF 2 TABLET used for?
GLIDUM MF 2 TABLET is used to manage type 2 diabetes mellitus in adults. This combination helps regulate blood sugar levels effectively in individuals whose blood sugar is not adequately controlled by diet, exercise, or a single diabetes medication. It helps reduce the risk of diabetes-related complications such as heart disease, nerve damage, or kidney issues.
How GLIDUM MF 2 TABLET works?
GLIDUM MF 2 TABLET contains a combination of two medicines namely, glimepiride and metformin. Glimepiride stimulates the pancreas to release more insulin, a hormone that lowers blood sugar levels. It also improves the body’s response to insulin. Metformin decreases the amount of sugar produced by the liver and reduces sugar absorption in the intestines. It also enhances the body’s ability to use insulin more effectively, making it a comprehensive treatment for blood sugar control.
What is the best time to take GLIDUM MF 2 TABLET?
It is usually recommended to take GLIDUM MF 2 TABLET with meals to minimize the risk of gastrointestinal side effects such as nausea or upset stomach. Following your doctor’s instructions regarding the timing is essential, as they might tailor the dose to suit your lifestyle and blood sugar patterns.
How many doses of GLIDUM MF 2 TABLET can be taken in a day?
The dosage depends on the individual’s medical condition, blood sugar levels, and response to treatment. Typically, it is taken once or twice daily with meals, but the exact dose should be determined by a doctor. Taking more than the prescribed dose can lead to hypoglycemia (low blood sugar), so it’s crucial to stick to the recommended schedule.
Can GLIDUM MF 2 TABLET be used during pregnancy?
The combination of Glimepiride + Metformin is generally not recommended during pregnancy due to the potential risk of harming the unborn baby. Instead, insulin is preferred for controlling blood sugar levels in pregnant women with diabetes. If you are pregnant or planning to conceive, consult your doctor for a safe treatment plan.
Can GLIDUM MF 2 TABLET control blood sugar levels?
Yes, this medicine is highly effective in controlling blood sugar levels in people with type 2 diabetes especially when diet, lifestyle changes and treatment with single agents does not yield optimum blood sugar control. However, its effectiveness also depends on maintaining a healthy lifestyle, including regular exercise and a balanced diet. Regular monitoring of blood sugar is essential to ensure the medication works optimally.
Who should not use GLIDUM MF 2 TABLET?
GLIDUM MF 2 TABLET is not suitable for individuals with severe kidney or liver disease, type 1 diabetes or diabetic ketoacidosis, known allergies to glimepiride, metformin, or any other ingredients in the medicine, or a history of lactic acidosis. Therefore, always inform your doctor about any pre-existing conditions or medications you are taking to avoid adverse effects.
What are the common side effects of GLIDUM MF 2 TABLET?
The most common side effects of GLIDUM MF 2 TABLET include nausea, vomiting, diarrhea, stomach pain, dizziness, or low blood sugar (hypoglycemia. Consult your doctor if any of these side effects worsens.
Is GLIDUM MF 2 TABLET safe?
Yes, GLIDUM MF 2 TABLET is generally safe when taken as prescribed. However, regular monitoring of kidney and liver function is necessary, as prolonged use can affect these organs. Additionally, following the recommended dose and schedule minimizes the risk of side effects.
Can GLIDUM MF 2 TABLET be taken on an empty stomach or before food?
No, it is best taken with food to reduce the risk of stomach upset and hypoglycemia. Food helps slow down the absorption of glimepiride, preventing a sudden drop in blood sugar levels, which can cause dizziness or weakness.
Is GLIDUM MF 2 TABLET safe for kidney patients?
GLIDUM MF 2 TABLET is not suitable for individuals with severe kidney disease, as it can increase the risk of lactic acidosis, a potentially life-threatening condition. Mild to moderate kidney impairment requires dose adjustment and close monitoring. Always consult your doctor before starting or continuing this medication.
How long will it take for GLIDUM MF 2 TABLET to control blood sugar levels?
GLIDUM MF 2 TABLET begins to lower blood sugar within a few hours of taking a dose. However, achieving optimal blood sugar control may take a few weeks, depending on individual response and adherence to the prescribed regimen, diet, and exercise plan.
Can I stop taking GLIDUM MF 2 TABLET once my blood sugar is controlled?
No, stopping the medication without your doctor’s advice can cause your blood sugar levels to rise again, leading to complications. Diabetes is a chronic condition requiring ongoing management. Your doctor may adjust the dose or switch medications based on your progress, but self-discontinuation is not recommended.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
19 Nov 2024