GLIBEDAC PM 5 Tablet 10's

Diabetes (3426)Rx required

Key Information

Generic Name

Generic Name Glibenclamide 5 mg+Metformin 500 mg+Pioglitazone 15 mg

Manufacturer

Innovative Pharmaceuticals Pvt Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

GLIBEDAC PM 5 TABLET is a combination of Glibenclamide, Pioglitazone and Metformin which belongs to the group of medicines called Antidiabetics. It is used in the management of type 2 diabetes when single drug therapy, diet and exercise alone are not able to control diabetes. Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue and blurred vision. Avoid alcohol consumption while taking GLIBEDAC PM 5 TABLET as it may increase the risk of

Uses

OF GLIBEDAC PM 5 TABLET To manage type 2 diabetes (when single drug therapy, diet and exercise alone are not able to control diabetes)

How It Works

GLIBEDAC PM 5 TABLET lowers blood sugar level, where glibenclamide stimulates the secretion of insulin hormone that regulates blood sugar level. Pioglitazone makes liver and muscle cells more sensitive to insulin to make it easier for sugar in the blood to get into the cells and metformin decreases the glucose production in liver (gluconeogenesis) and increases the insulin sensitivity to absorb blood sugar. All these actions together are helpful in maintaining blood sugar level in type 2 diabetes.

Directions for Use

Always take GLIBEDAC PM 5 TABLET as advised by your physician. Swallow this medicine with a glass of water before meals. Your doctor will decide a suitable dose and duration for you depending upon your age and disease condition.

Side Effects

taking GLIBEDAC PM 5 TABLET are headache, nausea, vomiting, weight gain, diarrhoea and abdominal pain. Consult your doctor if any of the side effect worsens. USES OF GLIBEDAC PM 5 TABLET To manage type 2 diabetes (when single drug therapy, diet and exercise alone are not able to control diabetes) HOW GLIBEDAC PM 5 TABLET WORKSGLIBEDAC PM 5 TABLET lowers blood sugar level, where glibenclamide stimulates the secretion of insulin hormone that regulates blood sugar level. Pioglitazone makes liver and muscle cells more sensitive to insulin to make it easier for sugar in the blood to get into the cells and metformin decreases the glucose production in liver (gluconeogenesis) and increases the insulin sensitivity to absorb blood sugar. All these actions together are helpful in maintaining blood sugar level in type 2 diabetes. DIRECTIONS FOR USEAlways take GLIBEDAC PM 5 TABLET as advised by your physician. Swallow this medicine with a glass of water before meals. Your doctor will decide a suitable dose and duration for you depending upon your age and disease condition. SIDE EFFECTS OF GLIBEDAC PM 5 TABLETCOMMON disturbance in vision anemia (decreased red blood cell count) weight gain hypoglycaemia (decreased blood sugar levels) joint pain headache, dizziness blood in urine erectile dysfunction altered taste sensation nausea, vomiting diarrhoea abdominal pain loss of appetite, heartburn shortness of breath UNCOMMON flatulence head spinning sensation (vertigo) sweating tiredness RARE signs of decreased blood platelets (such as bleeding or bruising) signs of low white blood cells (which makes prone to infections) Stop taking GLIBEDAC PM 5 TABLET and contact your doctor immediately if you experience any of the following side effects: signs of lactic acidosis (such as vomiting, stomach pain with muscle cramps, general feeling of being not well, severe tiredness and difficulty in breathing) abnormal liver function including yellowing of the skin and eyes (jaundice), problems with the bile flow (cholestasis), inflammation of the liver (hepatitis) or liver failure severe hypoglycaemia (signs include loss of consciousness, seizures or coma) signs of bladder cancer (blood in urine, pain when urinating or a sudden urge to urinate) broken bones blurred vision due to swelling (or fluid) at the back of the eye signs of allergic reaction (such as hives and swelling of the face, lips, tongue, or throat that may cause difficulty in breathing or swallowing)

Warnings & Precautions

& PRECAUTIONSPREGNANCYContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in pregnant woman. Consult your doctor before taking it. BREASTFEEDINGContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in breastfeeding woman. Consult your doctor before taking it. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you feel dizzy, weak or increased sweating after taking GLIBEDAC PM 5 TABLET. ALCOHOLContraindicatedDo not consume alcohol while taking GLIBEDAC PM 5 TABLET as it may increase the risk of side effects. KIDNEYContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in patients with kidney failure or kidney dysfunction. Consult your doctor before taking GLIBEDAC PM 5 TABLET. LIVERContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in patients with liver impairment. Consult your doctor before taking GLIBEDAC PM 5 TABLET. ALLERGYContraindicatedDo not take GLIBEDAC PM 5 TABLET if you are allergic to Glibenclamide, Pioglitazone or Metformin. LUNGSContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in patients with respiratory failure. Consult your doctor before taking GLIBEDAC PM 5 TABLET. HEART DISEASEContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in patients with heart failure, recent myocardial infarction (heart attack) or shock. Consult your doctor before taking GLIBEDAC PM 5 TABLET. USE IN PEDIATRICSContraindicatedGLIBEDAC PM 5 TABLET is not recommended for use in children. Consult child’s doctor for advice. USE IN GERIATRICSUse with CautionGLIBEDAC PM 5 TABLET should be used with caution in elderly patients. Consult your doctor before taking GLIBEDAC PM 5 TABLET. OTHERSGLIBEDAC PM 5 TABLET is not recommended for use if you have: diabetic ketoacidosis (serious diabetes complication where the body produces excess blood acids (ketones) or diabetic pre-coma (life-threatening disorder that causes unconsciousness due to high or low blood sugar levels) dehydration severe infection Before taking GLIBEDAC PM 5 TABLET, inform your doctor if you have: hypoglycaemia (low blood sugar) haemolytic anemia (rare blood disorder in which red blood cells are rapidly destroyed) lactic acidosis (build-up of lactic in the bloodstream)

Drug Interactions

SA. Drug-Drug interactions: Before taking GLIBEDAC PM 5 TABLET, inform your doctor if you are taking any of the following medicines: midazolam (used to reduce anxiety) gemfibrozil (used to manage high cholesterol) isoniazid, rifampicin (used to manage tuberculosis) furosemide (used to reduce swelling or oedema) medicines used to manage heart problems (Ex. amiloride, digoxin, procainamide, quinidine, propranolol, epinephrine) medicines used to suppress inflammation (Ex. prednisolone, dexamethasone) medicines used to manage mental health problems (Ex. moclobemide, amitriptyline) thyroid products like thyroxine (used to manage hypothyroidism) oral contraceptives such as ethinyl estradiol, desogestrel (used to manage pregnancy) phenytoin (used to manage fits) medicines used to provide relief from pain (Ex. aspirin, ibuprofen and celecoxib) chloramphenicol, sulfadiazine, cotrimoxazole and vancomycin (used to manage bacterial infections) warfarin (used to manage or manage blood clots) probenecid (used to manage gout) Overdosage: If you or anyone else accidentally takes too much of GLIBEDAC PM 5 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are weakness, rapid heartbeat, increased sweating, dizziness and difficulty in concentration. SYNOPSIS Drug : Glibenclamide, Pioglitazone, Metformin Pharmacological Category : Sulfonylureas, Thiazolidinediones, Biguanides Therapeutic Indication : Type 2 diabetes mellitus Dosage Forms : Tablet MORE INFORMATION Keep GLIBEDAC PM 5 TABLET out of reach of children Store at room temperature

Frequently Asked Questions

Common questions and answers about GLIBEDAC PM 5 Tablet 10's.

Q

What if I forget to take GLIBEDAC PM 5 TABLET?

A

If you forgot to take a dose of GLIBEDAC PM 5 TABLET, take it as soon as you remember. However, if it is time for the next dose of GLIBEDAC PM 5 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of GLIBEDAC PM 5 TABLET to compensate for the missed ones.

Q

What are the side effects of taking GLIBEDAC PM 5 TABLET?

A

The most common side effects of taking GLIBEDAC PM 5 TABLET are abnormal vision, respiratory infection, weight gain, numbness, decreased blood sugar (hypoglycemia), headache, dizziness, joint pain, impotence, back pain, shortness of breath, flatulence, nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and change in taste. Consult your doctor if any of the side effects worsen.

Q

Is GLIBEDAC PM 5 TABLET safe in pregnancy?

A

GLIBEDAC PM 5 TABLET is not recommended for use during pregnancy. Consult your doctor before taking it.

Q

Who should not take GLIBEDAC PM 5 TABLET?

A

GLIBEDAC PM 5 TABLET is not recommended for use if you have severe kidney disease, liver disease, heart failure, a history of heart failure, have recently had a heart attack, have severe problems with your circulation (such as shock), have breathing difficulties, type 1 diabetes mellitus, diabetic ketoacidosis or diabetic coma, bladder cancer, have blood in your urine that your doctor has not checked, or have dehydration due to severe diarrhea or vomiting, or have severe infections. Consult your doctor before taking it.

Q

Will taking a higher dose of GLIBEDAC PM 5 TABLET be more effective?

A

No, taking a higher dose of GLIBEDAC PM 5 TABLET will not be effective; rather, it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Article Information

I(

Written By

ity (HPRA). [Revised in May 2016]. [Accessed on 13th July 2022] https://www.hpra.ie/img/uploaded/swedocuments/2179143.PA0688_040_002.752e1eeb-1045-476a-97ac-9f7549199666.000001Product%20Leaflet%20Approved%205mg.160725.pdf 6. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in August 2020] [Accessed on 13th July 2022] https://www.medicines.org.uk/emc/files/pil.8836.pdf 7. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in June 2020]. [Accessed on 13th July 2022] https://www.medicines.org.uk/emc/files/pil.594.pdf USEFUL DIAGNOSTIC TESTS Glucose tolerance test Random blood sugar Fasting blood sugar Liver function tests   AUTHOR DETAILS Written By Srilekha. R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

28 Jun 2024

Tags

#diabetes (3426)#generic name glibenclamide 5 mg+metformin 500 mg+pioglitazone 15 mg