Gibtulio Met 12.5/500mg Tablet 10'S

Diabetes (3426)Rx required

Key Information

Generic Name

Generic Name Empagliflozin 12.5 mg+Metformin 500 mg

Manufacturer

Lupin Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

GIBTULIO MET 12.5/500MG TABLET is a combination of Empagliflozin and Metformin which belongs to the group of medicines called Antidiabetic agents. GIBTULIO MET 12.5/500MG TABLET is indicated for the management of type II diabetes mellitus in addition to diet and exercise among adults who remain unresponsive to therapy with either metformin alone or in combination with other antidiabetic medicines. GIBTULIO MET 12.5/500MG TABLET can also be used in combination with other medicines (including insulin) to achieve better control of blood sugar level. Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue and blurred vision. Along management with GIBTULIO MET 12.5/500MG TABLET follow regular exercise and diet plan as advised by your doctor to achieve better results. Avoid consumption of alcohol during management with GIBTULIO MET 12.5/500MG TABLET as it could aggravate your existing disease condition. Management with GIBTULIO MET 12.5/500MG TABLET must be discontinued for a short time, if you have any conditions that may be associated with dehydration (such as vomiting, diarrhea, fever, exposure to heat or less fluid intake). During management with GIBTULIO MET 12.5/500MG TABLET, your doctor will check your kidney function at least once a year or more frequently especially if you are elderly. For diabetic patients, it is recommended to check their foot regularly and adhere to any other advice regarding foot care given by your doctor. GIBTULIO MET 12.5/500MG TABLET is generally not recommended for use in pregnant or breastfeeding women, including children and adolescents (aged less than 18 years) due to lack of safety data. The most common

Uses

OF GIBTULIO MET 12.5/500MG TABLET To manage type II diabetes mellitus in addition to diet and exercise among adults who remain unresponsive to therapy with either metformin alone or in combination with other antidiabetic medicines

How It Works

GIBTULIO MET 12.5/500MG TABLET effectively reduces blood glucose levels, where empagliflozin acts by blocking the activity of a protein called sodium glucose co-transporter 2, which is responsible for the tubular reabsorption of glucose into the blood stream and metformin acts by reducing the amount of glucose released into the blood stream by the liver, thus helps in reducing blood glucose levels.

Directions for Use

Always take GIBTULIO MET 12.5/500MG TABLET as directed by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking GIBTULIO MET 12.5/500MG TABLET without informing your doctor.

Side Effects

taking GIBTULIO MET 12.5/500MG TABLET are hypoglycemia (low blood glucose), nausea, vomiting, diarrhea, excessive thirst, change in taste or dizziness. Consult your doctor if any of the side effects worsen. USES OF GIBTULIO MET 12.5/500MG TABLET To manage type II diabetes mellitus in addition to diet and exercise among adults who remain unresponsive to therapy with either metformin alone or in combination with other antidiabetic medicines HOW GIBTULIO MET 12.5/500MG TABLET WORKSGIBTULIO MET 12.5/500MG TABLET effectively reduces blood glucose levels, where empagliflozin acts by blocking the activity of a protein called sodium glucose co-transporter 2, which is responsible for the tubular reabsorption of glucose into the blood stream and metformin acts by reducing the amount of glucose released into the blood stream by the liver, thus helps in reducing blood glucose levels. DIRECTIONS FOR USEAlways take GIBTULIO MET 12.5/500MG TABLET as directed by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking GIBTULIO MET 12.5/500MG TABLET without informing your doctor. SIDE EFFECTS OF GIBTULIO MET 12.5/500MG TABLETCOMMON signs of low blood glucose levels (such as excessive hunger, headache, shaking, sweating, confusion, anxiety, fast heartbeat) urinary tract infection (pain or burning sensation while passing urine, cloudy urine, frequent urination, pain in the pelvis or mid-back pain) dehydration (unusual thirst, fainting or loss of consciousness, lightheadedness or dizziness upon standing) nausea, vomiting, diarrhea, constipation, stomach pain or loss of appetite thrush (genital yeast infection) skin rash, redness or itching with raised bumps or blisters change in taste excessive thirst UNCOMMON hives (raised itchy welts on the skin) painful urination Stop taking GIBTULIO MET 12.5/500MG TABLET and contact your doctor immediately if you experience any of the following side effects: severe allergic reactions (such as swelling of the face, lips, mouth, tongue or throat that may lead to difficulty in breathing or swallowing) symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty in breathing, muscle cramps, general weakness with severe tiredness or reduced body temperature) symptoms of diabetic ketoacidosis (such as nausea, vomiting, rapid weight loss, stomach pain, excessive thirst, fast and deep breathing, unusual sleepiness or tiredness, confusion, a sweet smell in your breath, a sweet or metallic taste in your mouth or a different odor to your urine or sweat) symptoms of fournier´s gangrene (such as pain, tenderness, redness or swelling of genitals or area between the genitals and the anus accompanied with fever or general weakness)

Warnings & Precautions

& PRECAUTIONSPREGNANCYContraindicatedGIBTULIO MET 12.5/500MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. BREASTFEEDINGContraindicatedGIBTULIO MET 12.5/500MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any tools or machines if you experience dizziness after taking GIBTULIO MET 12.5/500MG TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking GIBTULIO MET 12.5/500MG TABLET since it may increase the risk of lactic acidosis. KIDNEYContraindicatedGIBTULIO MET 12.5/500MG TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. LIVERContraindicatedGIBTULIO MET 12.5/500MG TABLET is not recommended for use in patients with liver problems. Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. ALLERGYContraindicatedDo not take GIBTULIO MET 12.5/500MG TABLET if you are allergic to Empagliflozin or Metformin. HEART DISEASEContraindicatedGIBTULIO MET 12.5/500MG TABLET is not recommended for use in patients with heart problems (such as recent heart attack or failure, cardiogenic shock (problems in blood circulation) or abnormal breathing). Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. USE IN PEDIATRICSContraindicatedGIBTULIO MET 12.5/500MG TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice. USE IN GERIATRICSUse with CautionGIBTULIO MET 12.5/500MG TABLET should be used with caution in elderly patients (aged 65 years or above). Your doctor may assess your kidney function more frequently during management with GIBTULIO MET 12.5/500MG TABLET. Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. OTHERSGIBTULIO MET 12.5/500MG TABLET is not recommended for use if you: have uncontrolled diabetes with nausea, vomiting, rapid weight loss, diarrhea, lactic acidosis (lactic acid build up in the bloodstream) or ketoacidosis (ketone bodies accumulate in the blood) have ever had a diabetic pre-coma have severe systemic infections affecting your lungs or kidneys have severe dehydration (either due to vomiting or diarrhea) are alcoholic have type I diabetes have an upcoming major surgery Before taking GIBTULIO MET 12.5/500MG TABLET inform your doctor if you: need to undergo an examination with iodination contrast agents (Ex. X-ray or scan)

Drug Interactions

SA. Drug-Drug interactions: Before taking GIBTULIO MET 12.5/500MG TABLET inform to your doctor, if you are taking any of these medicines: diuretics (medicines used to increase urine output) Ex. furosemide, chlorothiazide, hydrochlorothiazide other medicines used to manage diabetes (Ex. insulin, glipizide, glyburide, glimepiride) cimetidine (used to manage stomach ulcers) verapamil, ranolazine (used to manage chest pain) dolutegravir (used to manage HIV infection) trimethoprim (used to manage bacterial infection) isavuconazole (used to manage fungal infection) crizotinib, olaparib, vandetanib (used to manage certain forms of cancer) bronchodilators (used to manage asthma) Ex. salbutamol, salmeterol, formoterol, ipratropium corticosteroids (used to manage inflammation) Ex. dexamethasone, prednisolone medicines used to manage pain and inflammation (such as ibuprofen and celecoxib) medicines used to manage high blood pressure (Ex. captopril, enalapril, losartan, valsartan) medicines containing alcohol (such as cough syrup) iodinated contrast agents (used during an X-ray or scan) lithium (used to manage mental illness) Overdosage: If you or anyone else accidentally take too much of GIBTULIO MET 12.5/500MG TABLET, contact your doctor immediately or go to a nearest hospital straight away as it could lead to a life-threatening condition called lactic acidosis. Symptoms of lactic acidosis might include nausea, vomiting, stomach pain with muscle cramps, decreased heartbeat, general weakness with severe tiredness, difficulty in breathing or reduced body temperature. SYNOPSIS Drug : Empagliflozin, Metformin Pharmacological Category : Sodium-glucose co-transporter 2 (SGLT2) inhibitors; Biguanides Therapeutic Indication : Type II diabetes mellitus Dosage Forms : Tablet MORE INFORMATION Keep GIBTULIO MET 12.5/500MG TABLET out of reach of children Store at room temperature

Frequently Asked Questions

Common questions and answers about Gibtulio Met 12.5/500mg Tablet 10'S.

Q

Can I consume alcohol while taking GIBTULIO MET 12.5/500MG TABLET?

A

No, avoid consumption of alcohol while taking GIBTULIO MET 12.5/500MG TABLET since it may increase the risk of lactic acidosis and diabetic ketoacidosis. Before taking GIBTULIO MET 12.5/500MG TABLET inform your doctor if you are alcoholic.

Q

Can GIBTULIO MET 12.5/500MG TABLET makes me feel more tired?

A

Yes, GIBTULIO MET 12.5/500MG TABLET can cause severe tiredness, unusual thirst, lightheadedness or dizziness upon standing in some individuals. Consult your doctor immediately if you experience any unusual symptoms after taking GIBTULIO MET 12.5/500MG TABLET.

Q

Is GIBTULIO MET 12.5/500MG TABLET safe to use in elderly patients?

A

GIBTULIO MET 12.5/500MG TABLET should be used with caution in elderly patients (aged 65 years or above), consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET. Your doctor might check your kidney function at least once a year or more frequently to avoid kidney damage.

Q

Can GIBTULIO MET 12.5/500MG TABLET be used in patients with heart disease?

A

GIBTULIO MET 12.5/500MG TABLET is not recommended for use in patients with heart problems such as recent heart attack or failure, cardiogenic shock (problems in blood circulation) or abnormal breathing. Consult your doctor before taking GIBTULIO MET 12.5/500MG TABLET.

Q

What is GIBTULIO MET 12.5/500MG TABLET used for?

A

GIBTULIO MET 12.5/500MG TABLET is used to manage type II diabetes mellitus in addition to diet and exercise among adults who remain unresponsive to therapy with either metformin alone or in combination with other antidiabetic medicines. It is not recommended for use in patients with type-1 diabetes.

Article Information

DW

Written By

DETAILS Written By Dr. R. Dinesh John Rajkumar

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

27 Nov 2023

Tags

#diabetes (3426)#generic name empagliflozin 12.5 mg+metformin 500 mg