Gerzone Injection 1'S
Key Information
Generic Name
Generic Name Cefoperazone 1000 mg+Sulbactam 500 mg
Manufacturer
Zydus Healthcare Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT GERZONE INJECTIONGERZONE INJECTION is a combination of Cefoperazone and Sulbactam, which belongs to the group of medicines called Antibiotics. It is used to manage various bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia (serious bloodstream infection), meningitis (inflammation of brain and spinal cord membranes, typically caused by an infection), and skin and soft tissue infections. It is also used to manage bone and joint infections, gonorrhoea (sexually transmitted bacterial infection), endometritis (inflammation of the uterine lining due to infection), pelvic inflammatory disease (infection of the female reproductive organs), and other infections of the genital tract. Bacterial infections are caused by the multiplication of specific harmful strains of bacteria anywhere in the body. It is characterized by symptoms such as fever, nausea, vomiting, headache, tiredness, and swollen lymph nodes in the neck, armpits, groin, or elsewhere. Before receiving GERZONE INJECTION, inform your doctor if you have impaired kidney function, severe biliary obstruction (blockage of the bile ducts), severe liver disease, or malabsorption conditions, and have a schedule for laboratory tests (such as measuring glucose in the urine). GERZONE INJECTION should be used with caution in pregnant and breastfeeding women only if advised by the doctor. Also, it should be used with caution in children and elderly patients. The most common
Uses
OF GERZONE INJECTIONManages bacterial infections such as: Respiratory tract infections Urinary tract infections (upper and lower) Intra-abdominal infections Septicaemia Meningitis Skin and soft tissue infections Bone and joint infections Pelvic inflammatory disease Endometritis Gonorrhoea Other infections of the genital tract
How It Works
GERZONE INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections.
Directions for Use
GERZONE INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection.
Side Effects
receiving GERZONE INJECTION are diarrhea, nausea, and vomiting. Inform your doctor if any of these side effects bother you. USES OF GERZONE INJECTIONManages bacterial infections such as: Respiratory tract infections Urinary tract infections (upper and lower) Intra-abdominal infections Septicaemia Meningitis Skin and soft tissue infections Bone and joint infections Pelvic inflammatory disease Endometritis Gonorrhoea Other infections of the genital tract HOW GERZONE INJECTION WORKSGERZONE INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections. DIRECTIONS FOR USEGERZONE INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection. SIDE EFFECTS OF GERZONE INJECTIONCOMMON Diarrhea Nausea, vomiting Coagulopathy (impairment in the blood's ability to clot) UNCOMMON Headache Itching Raised red rashes (urticaria) Pain or inflammation of a vein at the site of injection Fever, chills RAREInform your doctor immediately if you experience any of the following side effects after receiving GERZONE INJECTION: Allergic reactions Skin reactions such as toxic epidermal necrolysis, Stevens-Johnson syndrome, and dermatitis exfoliative (signs include blistering and peeling of the skin). Persistent bleeding
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredGERZONE INJECTION should be used during pregnancy only if considered clearly necessary. Consult your doctor before receiving GERZONE INJECTION. BREASTFEEDINGUse with CautionGERZONE INJECTION should be used with caution in breast-feeding women, as a small amount of this medicine is excreted in the breast milk. Consult your doctor before receiving GERZONE INJECTION. DRIVING AND USING MACHINESSafeGERZONE INJECTION does not affect your ability to drive or use machinery. ALCOHOLContraindicatedAvoid consuming alcohol while receiving GERZONE INJECTION because it may cause flushing, sweating, headaches, and an increase in the heartbeat. KIDNEYUse with CautionGERZONE INJECTION should be used with caution in patients with impaired kidney function. Consult your doctor before receiving GERZONE INJECTION. LIVERUse with CautionGERZONE INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor before receiving GERZONE INJECTION. ALLERGYContraindicatedDo not receive GERZONE INJECTION if you are allergic to cefoperazone, sulbactam, beta-lactam antibiotics (such as Penicillins and cephalosporins (Ex. cefuroxime)) or any other ingredients of this medicine. USE IN PEDIATRICSUse with CautionGERZONE INJECTION should be used with caution in children. Your child’s doctor may adjust the dose depending upon the child's body weight. Consult your child’s doctor for advice. USE IN GERIATRICSUse with CautionGERZONE INJECTION should be used with caution in elderly patients. Consult your doctor before receiving it. OTHERSBefore receiving GERZONE INJECTION, inform your doctor if you: Have poor diet and malabsorption conditions Have any scheduled laboratory tests (such as measuring glucose in the urine)
Drug Interactions
SA. Drug-Drug interactions: Before receiving GERZONE INJECTION, inform your doctor if you are taking any of the following medicines: Medicines used to manage bacterial infections, such as aminoglycosides (Ex. gentamicin, tobramycin, amikacin, and streptomycin) Oral anti-coagulants (Ex. warfarin) (used to manage or manage blood clots) Overdosage: GERZONE INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms, such as neurologic effects (such as fits). SYNOPSIS Drug : Cefoperazone, Sulbactam Pharmacological Category : Cephalosporin; Beta-lactamase inhibitors Therapeutic Indication : Various bacterial infections Dosage Forms : Injection MORE INFORMATIONSTORAGE Store below 25°C and protect from light
Frequently Asked Questions
Common questions and answers about Gerzone Injection 1'S.
What is GERZONE INJECTION used for?
GERZONE INJECTION is a combination of Cefoperazone and Sulbactam, which belongs to the group of medicines called antibiotics. It is used to manage several bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia, meningitis, skin and soft tissue infections, bone and joint infections, gonorrhoea, endometritis, pelvic inflammatory disease, and other infections of the genital tract.
How does GERZONE INJECTION work?
GERZONE INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections.
Is GERZONE INJECTION safe for kidneys?
GERZONE INJECTION should be used with caution in patients with impaired kidney function. Consult your doctor before receiving GERZONE INJECTION.
How GERZONE INJECTION is administered?
GERZONE INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection.
Is GERZONE INJECTION safe to use in patients with liver disease?
GERZONE INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor for advice before receiving GERZONE INJECTION.
What are the side effects of GERZONE INJECTION?
The most common side effects of receiving GERZONE INJECTION are diarrhea, nausea, vomiting, and coagulopathy (impairment in the blood's ability to clot). Inform your doctor if any of these side effects bother you.
Is GERZONE INJECTION safe during pregnancy?
GERZONE INJECTION should be used during pregnancy only if considered clearly necessary. Consult your doctor before receiving GERZONE INJECTION.
Can GERZONE INJECTION be used in children?
GERZONE INJECTION should be used with caution in children. Your child’s doctor may adjust the dose depending upon the child's body weight. Consult your child’s doctor for advice.
Who should not use GERZONE INJECTION?
Do not receive GERZONE INJECTION if you are allergic to cefoperazone, sulbactam, beta-lactam antibiotics (such as Penicillins and cephalosporins (Ex. cefuroxime)) or any other ingredients of this medicine.
What precautions must be taken while using GERZONE INJECTION?
Before receiving GERZONE INJECTION, inform your doctor if you have impaired kidney function, severe biliary obstruction (blockage of the bile ducts), severe liver disease, poor diet and malabsorption conditions, or have any scheduled laboratory tests (such as measuring glucose in the urine).
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
26 Jul 2024