GABATRYP Tablet 10's

Neuropathic Pain (649)Rx required

Key Information

Generic Name

Generic Name Amitriptyline 10 mg+Gabapentin 300 mg

Manufacturer

Propel Healthcare

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

GABATRYP TABLET is a combination of Amitriptyline and Gabapentin which belongs to the group of medicines called Tricyclic Antidepressants and Antiepileptics. It is used in the management of neuropathic pain in adults. Neuropathic pain is a long-term weakness, numbness or pain caused by damage to the nerves in hands and legs characterized by a feeling of hot, burning, throbbing, shooting, sharp, tingling, numbness. GABATRYP TABLET is not recommended for use in patients with severe liver disease and heart problems and it should be used with caution in patients having kidney problems or undergoing haemodialysis. Do not stop taking GABATRYP TABLET suddenly, as this may lead to increased risk of seizure. GABATRYP TABLET is not recommended for use in pregnant woman especially during the last few months of the pregnancy. Do not take GABATRYP TABLET if you are breast-feeding as it may pass through breast milk to the baby. Consult your doctor for advice before taking it. GABATRYP TABLET is not recommended for use in children and adolescents below 18 years of age and should be used with caution in elderly patients aged 65 years and above. Consult your doctor for advice before taking GABATRYP TABLET. The most common

Uses

OF GABATRYP TABLET Manage neuropathic pain (long term pain caused by damage to the nerves) in adults

How It Works

GABATRYP TABLET works effectively in reducing the neuropathic pain where Amitriptyline effects are related to its mood-altering activities which acts by increasing the concentration of the neurotransmitters called serotonin and norepinephrine as these substances are found to be low in the anxiety patients and Gabapentin acts by blocking the pain signals travelling through the damaged nerves and the brain and hence manages nerve pain.

Directions for Use

Take GABATRYP TABLET as advised by your physician. Swallow GABATRYP TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking GABATRYP TABLET without consulting your doctor.

Side Effects

taking GABATRYP TABLET are dizziness, drowsiness, muscle pain, nausea, vomiting and stomach pain. Consult your doctor if any of these side effect worsens. USES OF GABATRYP TABLET Manage neuropathic pain (long term pain caused by damage to the nerves) in adults HOW GABATRYP TABLET WORKSGABATRYP TABLET works effectively in reducing the neuropathic pain where Amitriptyline effects are related to its mood-altering activities which acts by increasing the concentration of the neurotransmitters called serotonin and norepinephrine as these substances are found to be low in the anxiety patients and Gabapentin acts by blocking the pain signals travelling through the damaged nerves and the brain and hence manages nerve pain. DIRECTIONS FOR USETake GABATRYP TABLET as advised by your physician. Swallow GABATRYP TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking GABATRYP TABLET without consulting your doctor. SIDE EFFECTS OF GABATRYP TABLETCOMMON sleepiness/drowsiness, dizziness, lack of coordination, tiredness dizziness while standing up (orthostatic hypotension) irregular or fast heartbeat, heart block eating disorder characterized by low body weight, increased appetite anger, nervousness, difficulty with thinking, confusion, mood changes, depression, anxiety jerky movements, loss of memory, tremor, headache, sensitive skin, decreased sensation (numbness), unusual eye movement, increased, decreased or absent reflexes, difficulty with speaking and coordination, difficulty sleeping blurred vision, double vision feeling of spinning (vertigo) high blood pressure difficulty in breathing, sore throat, cough, dry and congested nose vomiting, nausea problems with teeth, inflamed gums stomach pain, diarrhea, indigestion, constipation, flatulence, dry mouth or throat facial swelling, bruises, rash, itching, acne muscles and joint pain, back pain, muscle twitching difficulties with erection (impotence) in male swelling in the legs and arms, weakness, pain, feeling unwell, difficulty with walking increase in weight rhythmic shaking movements of body parts excessive sweating (anxiety) slurred or slow speech agitation (anxiety) sexual disturbances disturbance in attention altered taste sensation dilated pupils UNCOMMON allergic reaction such as hives decreased movements difficulty in swallowing swelling of the face, limbs and trunk excitement, nightmares fits, ringing in ears nettle rash (urticaria) difficulties passing urine increased breast milk production or its outflow without breast feeding increased pressure in the eyeball RARE loss of consciousness decreased appetite delirium (especially in elderly patients), hallucinations swelling of the salivary glands hair loss increased sensitivity to sunlight breast enlargement in men weight loss Stop taking GABATRYP TABLET and contact your doctor immediately if you experience any of the following side effects: swelling of the skin, lips and face rash and redness and/or hair loss signs of acute pancreatitis such as nausea and vomiting, persistent stomach pain breathing problems, swollen glands severe weakness, unusual bruising or bleeding frequent infections, muscle pain hives (nettle rash), facial swelling due to allergies (Quincke’s oedema or angioedema), difficulty in breathing, severe dizziness with very fast heartbeat and sweating blistering of the skin and rapid deterioration of general condition, peeling of skin (including slight bleeding) of eyes, nose, mouth/ lips or genitals (Stevens Johnson-Syndrome, Lyell-Syndrome, Erythema multiforme) and sensitivity to light eye pain, intermittent blurred vision, rainbow vision jaundice (yellowing of the skin or white of the eyes) persistent sore throat and fever suicidal thoughts

Warnings & Precautions

& PRECAUTIONSPREGNANCYGABATRYP TABLET is not recommended for use in pregnant woman unless considered clearly necessary, especially during the last few months of pregnancy as the new-born may have withdrawal symptoms such as tremors (shaking movements), irregular breathing, irritability, increased muscle tension, poor drinking, crying loudly, urinary retention and constipation. Consult your doctor before taking GABATRYP TABLET. BREASTFEEDINGDo not take GABATRYP TABLET if you are breast-feeding as it may pass through breast milk to the baby. Consult your doctor before taking GABATRYP TABLET. DRIVING AND USING MACHINESDo not drive or operate any machines because GABATRYP TABLET may cause dizziness, drowsiness and tiredness. ALCOHOLAvoid consumption of alcohol while taking GABATRYP TABLET as it may cause sleepiness or dizziness. KIDNEYGABATRYP TABLET should be used with caution in patients with kidney problems or those who are undergoing haemodialysis. Consult your doctor before taking GABATRYP TABLET. LIVERGABATRYP TABLET is not recommended for use in patients having severe liver disease. Consult your doctor before taking GABATRYP TABLET. ALLERGYDo not take GABATRYP TABLET if you are allergic to Amitriptyline or Gabapentin. LUNGSGABATRYP TABLET should be used with caution in patients with respiratory disorders. Consult your doctor before taking GABATRYP TABLET. HEART DISEASEGABATRYP TABLET is not recommended for use in patients who had heart attack (myocardial infarction), disturbances in heart rhythm, heart block or coronary artery disease. It should be used with caution in patients with pre-existing heart disease. Consult your doctor before taking GABATRYP TABLET. OTHERSBefore taking GABATRYP TABLET, inform your doctor if you: have acute pancreatitis with signs of persistent stomach pain, nausea and vomiting have nervous system disorders have a problem resulting in low levels of potassium or magnesium or high levels of potassium in the blood have a planned surgery have an overactive thyroid gland Use in pediatrics: GABATRYP TABLET is not recommended for use in children and adolescents below 18 years of age. Consult your child’s doctor for advice before administration of GABATRYP TABLET. Use in geriatrics: GABATRYP TABLET should be taken with caution in elderly patients (aged 65 years or above) especially in patients with impaired kidney function. Consult your doctor before taking GABATRYP TABLET.

Drug Interactions

SA. Drug - Drug interactions: Before taking GABATRYP TABLET, inform your doctor, if you are taking any of the following medicines: antacids such as aluminum hydroxide and magnesium hydroxide (medicines used to reduce heart burn, indigestion) fluoxetine, paroxetine, fluvoxamine, duloxetine, bupropion and monoamine oxidase inhibitors like phenelzine, iproniazid, isocarboxazid, nialamide or tranylcypromine (medicines used to manage depression) terbinafine, itraconazole, fluconazole, ketoconazole, (used to manage fungal infections) erlotinib (medicine used for certain types of cancer) warfarin and phenprocoumon (medicines used as a blood thinning agent) rifampicin (medicine used to manage tuberculosis) St john’s wort (hypericum perforatum) (used to manage mild depression) glyceryl trinitrate, adrenaline, ephedrine, isoprenaline, noradrenaline, atenolol, propranolol (medicines used to manage heart disease) phenylephrine and phenylpropanolamine (medicines used to manage cough and cold) medicines to manage high blood pressure (Ex. diltiazem and verapamil, betanidine, reserpine, methyldopa, guanethidine and clonidine) medicines to manage parkinson’s disease and gastrointestinal disorders (Ex. atropine, hyoscyamine) thioridazine (medicine used to manage schizophrenia) nefopam, tramadol, morphine, buprenorphine (used to manage pain) barbiturates like phenobarbital, pentobarbital (medicines used to manage insomnia) or other sleeping medicines like triazolam, zolpidem cimetidine (used to manage stomach ulcers) methylphenidate (used to manage ADHD-attention-deficit/hyperactivity disorder) ritonavir (medicine used to manage HIV) oral contraceptives valproic acid, phenytoin and carbamazepine (medicines used to manage epilepsy) thyroxine (used to manage underactive thyroid) baclofen (medicine used as muscle relaxant) Overdosage: If you or anyone else accidentally takes too much of GABATRYP TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of GABATRYP TABLET includes loss of consciousness, dizziness, double vision, slurred speech, drowsiness, diarrhoea, dilated pupils, fast or irregular heartbeats, difficulties passing water, dry mouth and tongue, intestinal blockage, low blood pressure, weak pulse, pallor (pale skin), difficulty in breathing, blue discolouration of the skin, decreased heart rate, drowsiness, loss of consciousness, coma, fits, fever, agitation, confusion, hallucinations, uncontrolled movements, various cardiac symptoms such as heart block, heart failure, cardiogenic shock, metabolic acidosis, low levels of blood potassium (hypokalaemia). SYNOPSIS Drug : Amitriptyline, Gabapentin Pharmacological Category : Tricyclic Antidepressants, Antiepileptics Therapeutic Indication : Neuropathic pain Dosage Forms : Tablet MORE INFORMATION keep GABATRYP TABLET out of reach of children Store GABATRYP TABLET at room temperature

Article Information

DW

Written By

DETAILS Written By Dr. R. Dinesh John Rajkumar

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

10 Dec 2022

Tags

#neuropathic pain (649)#generic name amitriptyline 10 mg+gabapentin 300 mg