Folitrax 20mg Injection 1ml

Cancer Oncology (448)Rx required

Key Information

Generic Name

Generic Name Methotrexate 20 mg

Manufacturer

Ipca Laboratories Ltd

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT FOLITRAX 20MG INJECTIONFOLITRAX 20MG INJECTION contains Methotrexate, which belongs to the group of medicines called Antimetabolites. FOLITRAX 20MG INJECTION is used to manage active rheumatoid arthritis in adults. It is also used to manage polyarthritic forms (characterized by the involvement of five or more joints), which are severe, active, and idiopathic in nature and affect young people (Juvenile Idiopathic Arthritis, or JIA). FOLITRAX 20MG INJECTION is also used to manage psoriasis. In addition, FOLITRAX 20MG INJECTION is also used to manage Crohn’s disease and various cancers such as acute lymphocytic lymphoma, Non-Hodgkin’s Lymphoma, breast cancer, cervical cancer, bladder cancer, etc. Rheumatoid arthritis is an autoimmune and inflammatory disease, which means that your immune system attacks healthy cells in your body by mistake, causing inflammation (painful swelling) in the affected parts of the body. Psoriasis is a skin condition characterized by itchy scales that is not responsive to conventional managements such as phototherapy and retinoids. Crohn’s disease is an inflammatory disease affecting the intestine. Before getting FOLITRAX 20MG INJECTION administered, it is recommended to inform the doctor about your medical and family history, including the list of medicines (prescription, non-prescription medicines, and herbal medicines) that are being taken, before receiving FOLITRAX 20MG INJECTION. Also, FOLITRAX 20MG INJECTION is not recommended for children less than the age of 3, pregnant and nursing women, women planning pregnancy, those who drink huge amounts of alcohol, and patients suffering from liver and kidney impairment. Caution must be exercised by patients suffering from lung disorders, blood disorders, and gastric disorders before receiving FOLITRAX 20MG INJECTION. Care must be taken to avoid taking products containing caffeine, such as black tea, coffee, and cold drinks, while receiving FOLITRAX 20MG INJECTION. The common

Uses

OF FOLITRAX 20MG INJECTIONIt is used to manage: active rheumatoid arthritis (adults) severe arthritis occurring due to unknown reasons (idiopathic and juvenile, which is non-responsive to conventional painkillers) psoriasis Crohn’s disease polyarthritic forms cancer (acute lymphocytic lymphoma, meningeal leukemia) (a type of cancer of white blood cells in the ovary, breast, cervix, lungs, bones, and bladder

How It Works

FOLITRAX 20MG INJECTION contains Methotrexate, a disease-modifying antirheumatic drug (DMARDs) which interferes with the growth of those cells in the body that reproduce quickly. As a result, the growth of those cells gets retarded, thus serving as an anti-tumour agent. Also, FOLITRAX 20MG INJECTION decreases the undesired reactions of the body’s own immune-defense mechanism, thereby working as an effective immunosuppressant. In addition, it also exhibits anti-inflammatory effects, thereby reducing pain, swelling, and redness. As a result, FOLITRAX 20MG INJECTION manages the symptoms associated with diseases such as rheumatoid arthritis and psoriasis.

Directions for Use

FOLITRAX 20MG INJECTION will be administered to you into a muscle (intramuscularly) only by a doctor or a nurse. Your doctor will administer the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects

blood cells. Consult a doctor if any of the above side effects worsen after receiving FOLITRAX 20MG INJECTION. USES OF FOLITRAX 20MG INJECTIONIt is used to manage: active rheumatoid arthritis (adults) severe arthritis occurring due to unknown reasons (idiopathic and juvenile, which is non-responsive to conventional painkillers) psoriasis Crohn’s disease polyarthritic forms cancer (acute lymphocytic lymphoma, meningeal leukemia) (a type of cancer of white blood cells in the ovary, breast, cervix, lungs, bones, and bladder HOW FOLITRAX 20MG INJECTION WORKSFOLITRAX 20MG INJECTION contains Methotrexate, a disease-modifying antirheumatic drug (DMARDs) which interferes with the growth of those cells in the body that reproduce quickly. As a result, the growth of those cells gets retarded, thus serving as an anti-tumour agent. Also, FOLITRAX 20MG INJECTION decreases the undesired reactions of the body’s own immune-defense mechanism, thereby working as an effective immunosuppressant. In addition, it also exhibits anti-inflammatory effects, thereby reducing pain, swelling, and redness. As a result, FOLITRAX 20MG INJECTION manages the symptoms associated with diseases such as rheumatoid arthritis and psoriasis. DIRECTIONS FOR USEFOLITRAX 20MG INJECTION will be administered to you into a muscle (intramuscularly) only by a doctor or a nurse. Your doctor will administer the correct dose and duration for you depending on your age, body weight, and disease condition. SIDE EFFECTS OF FOLITRAX 20MG INJECTIONCOMMON loss of appetite nausea vomiting stomach pain inflammation and ulcers in the mouth and throat increase in the level of liver enzymes decreased count of white and red blood cells decreased count of platelets headache tiredness drowsiness inflammation of the lungs along with the production of a dry, non-productive cough and shortness of breath fever diarrhea (frequent loose stools) development of itching, rash, and reddening of the skin decreased resistance to infection UNCOMMON confusion depression fits inflammation of blood vessels liver disorders diabetes sensitivity to light brown skin loss of hair increase in rheumatic nodules viral infection joint or muscle pain porous bones (osteoporosis) painful urination severe allergic reactions development of inflammation and ulcers (vagina) eating disorder resulting in high weight loss (anorexia) pain in the chest cough inability to pass urine (dysuria) nose bleeding development of fatty liver red eyes (conjunctivitis) disturbances in the level of electrolytes RARE inflammation of the sac around the heart along with the accumulation of fluid in the sac around the heart severe vision disturbances mood fluctuations low blood pressure blood clots asthma (difficult breathing along with the production of wheezing sounds) changed colour of nails development of acne (pimples) development of red or purple spots due to vessel bleeding kidney problems defective formation of sperm menstruation disorders nodulosis (small tissue growth at the hands and elbows, on Achilles tendons) loss of libido or impotence chills and fever (without any detectable pathogen) immunosuppression decreased resistance to infection abnormal tissue cell changes metabolic disorders development of breasts in men tinnitus (ringing sensation in the ears) sweating inflammatory conditions of the heart thromboembolic complications plaque-like erosions on the skin inflammation of the pharynx and gingiva stress fracture Stop receiving FOLITRAX 20MG INJECTION and consult your doctor immediately if you experience any of the following: sudden (acute) bleeding from the lungs characterized by spitting and/or coughing blood general weakness of muscles, disturbance in the vision, changes in pattern of thinking, memory, and orientation that lead to confusion and changes in personality (progressive multifocal leukoencephalopathy) general illness along with a dry, irritating cough and shortness of breath, breathlessness during rest, pain in the chest, or fever, indicative of lung problems severe peeling and/or blisters on the skin unusual bleeding and the formation of bruises severe, frequent, loose stools (diarrhea) presence of ulcers in the mouth black or tar-like stools presence of blood in urine and stools yellowing of the skin and eyes increased thirst fits (convulsions) blurred and/or decreased vision redness, swelling of the hands, ankles, feet, lips, mouth, and throat, leading to difficulty swallowing and/or breathing feeling of fainting symptoms of infection such as fever, body ache, and sore throat severe headache along with stiffness in the neck, fever, nausea, and vomiting, indicative of inflamed membranes of the brain (acute aseptic meningitis) severe skin rash such as blistering of skin indicative of Stevens Johnson syndrome or burned skin syndrome (toxic epidermal necrolysis/Lyell’s syndrome)

Warnings & Precautions

& PRECAUTIONSPREGNANCYContraindicatedFOLITRAX 20MG INJECTION is not recommended if you are pregnant and/or are planning to become pregnant since it can be harmful to the foetus (growing baby) and lead to various malformations. Consult your doctor before receiving FOLITRAX 20MG INJECTION. BREASTFEEDINGContraindicatedFOLITRAX 20MG INJECTION is not recommended if you are a nursing mother. Consult your doctor before receiving FOLITRAX 20MG INJECTION. DRIVING AND USING MACHINESContraindicatedFOLITRAX 20MG INJECTION is not recommended if you feel tired and/or dizzy after receiving the medicine. Consult your doctor prior to receiving FOLITRAX 20MG INJECTION. ALCOHOLContraindicatedFOLITRAX 20MG INJECTION is not recommended if you consume large amounts of alcohol. Consult your doctor before receiving FOLITRAX 20MG INJECTION. KIDNEYContraindicatedFOLITRAX 20MG INJECTION is not recommended if you are diagnosed with a severe kidney disorder. Consult your doctor before receiving FOLITRAX 20MG INJECTION. LIVERContraindicatedFOLITRAX 20MG INJECTION is not recommended if you are diagnosed with a severe liver disorder. Consult your doctor before receiving FOLITRAX 20MG INJECTION. ALLERGYContraindicatedFOLITRAX 20MG INJECTION is not recommended if you are allergic to methotrexate and/or any other constituent of FOLITRAX 20MG INJECTION. Consult your doctor before receiving FOLITRAX 20MG INJECTION. LUNGSUse with CautionFOLITRAX 20MG INJECTION is recommended to be received with caution if you have issues with lung function and are diagnosed with ascites and pleural effusion. Consult your doctor before receiving FOLITRAX 20MG INJECTION. USE IN PEDIATRICSContraindicatedFOLITRAX 20MG INJECTION is not recommended for children below the age of 3 years due to a lack of safety data. If needed, your doctor will administer the right dose depending on your child’s age, body weight, and disease condition. Consult the doctor before receiving FOLITRAX 20MG INJECTION. USE IN GERIATRICSUse with CautionFOLITRAX 20MG INJECTION is recommended to be administered with caution and in a lower dosage to elders due to diminished function of the liver and kidneys and reduced folate levels in the blood in old age. Consult the doctor before receiving FOLITRAX 20MG INJECTION. OTHERSFOLITRAX 20MG INJECTION is not recommended for use if you: have blood disorders have an impaired immune system have a severe and/or existing infection (Ex. tuberculosis, HIV) have ulcers in the gastro-intestinal tract are receiving vaccinations containing live vaccines have bone marrow suppression have certain immunodeficiency syndromes have scheduled a surgery (which requires anesthesia) have ulcerative colitis characterized by bleeding from the bowel are malnourished Before receiving FOLITRAX 20MG INJECTION, inform your doctor if you: have diabetes mellitus are overweight have a tooth infection, such as an abscess in a tooth have increased and/or unusual bleeding or bruising suffer folate deficiency of folate are receiving radiotherapy for various conditions, such as X-rays and UV-rays

Drug Interactions

SA. Drug-Drug Interactions: Before receiving FOLITRAX 20MG INJECTION, inform your doctor if you are taking any of the following medicines: other medicines used to manage rheumatoid arthritis and psoriasis (Ex. leflunomide, phenylbutazone, or amidopyrine) medicines used in organ transplantation (Ex. azathioprine) medicines used to manage skin conditions (Ex. retinoids) medicines used to manage fits (Ex. phenytoin) medicines used in cancer medicines used to induce sleep (Ex. barbiturates such as phenobarbitone) medicines used to induce calmness and relieve anxiety (Ex. tranquilizers such as diazepam) medicines used for oral contraception (Ex. estrogen) medicines used to manage gout (Ex. probenecid) medicines used to manage bacterial infections (Ex. amoxicillin) medicines used to manage malaria (Ex. pyrimethamine) medicines used to manage severe heartburn or ulcers (Ex. omeprazole) medicines used to manage asthma (Ex. theophylline) medicines used to suppress hyperactive immune system (Ex. diphenylhydantoin, amidopyrine derivatives) medicines used to manage various infections (Ex. pyrimethamine and cotrimoxazole) medicines used to manage increased cholesterol levels (Ex. Cholestyramine) medicines used to manage heart problems (Ex. Amiodarone) medicines used to manage diabetes (Ex. Metformin) B. Drug-food interactions: It is recommended to avoid the consumption of drinks containing caffeine, such as black tea, coffee, and soft drinks, to manage dehydration. Overdosage: FOLITRAX 20MG INJECTION will be administered only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. Contact your doctor immediately. However, if you experience any unusual symptoms like an easy tendency to bruise or bleed, nausea, vomiting, or feeling unusual weakness, along with the development of mouth sores, black or bloody stools, coughing up blood and vomiting that looks like coffee grounds, or decreased urination. SYNOPSIS Drug : Methotrexate Pharmacological Category : Anti-metabolites Therapeutic Indication : Rheumatoid Arthritis, Psoriasis, Cancer Dosage Forms : Injection, Gel, Capsule, Tablet MORE INFORMATION Keep FOLITRAX 20MG INJECTION out of the reach and sight of children Store FOLITRAX 20MG INJECTION at a temperature below 25°C

Frequently Asked Questions

Common questions and answers about Folitrax 20mg Injection 1ml.

Q

What is FOLITRAX 20MG INJECTION used for?

A

FOLITRAX 20MG INJECTION contains Methotrexate, which belongs to the group of medicines called Antimetabolites. It is used to manage active rheumatoid arthritis in adults. It is also used to manage polyarthritic forms (characterized by the involvement of five or more joints), which are severe, active, and idiopathic in nature and affect young people (Juvenile Idiopathic Arthritis, or JIA). FOLITRAX 20MG INJECTION is also used to manage psoriasis, which is a skin condition characterized by itchy scales that is not responsive to conventional management such as phototherapy and retinoids.

Q

Can I receive FOLITRAX 20MG INJECTION during pregnancy?

A

FOLITRAX 20MG INJECTION is not recommended for use in pregnant women and/or in women who are planning pregnancy because it can be harmful for the foetus (a growing baby in the womb). Consult your doctor before receiving it.

Q

Can I receive FOLITRAX 20MG INJECTION if I am breastfeeding?

A

FOLITRAX 20MG INJECTION is not recommended for nursing mothers due to a lack of safety data. Consult your doctor before receiving it.

Q

Can FOLITRAX 20MG INJECTION be received by children?

A

FOLITRAX 20MG INJECTION is not recommended to be received by children less than 3 years of age. Consult your doctor before receiving FOLITRAX 20MG INJECTION.

Q

Can FOLITRAX 20MG INJECTION be used by the elderly?

A

FOLITRAX 20MG INJECTION is recommended to be administered with caution and in a lower dosage to elders due to diminished function of the liver and kidneys and reduced folate levels in the blood in old age. Consult the doctor before receiving it.

Q

Is there any specific food to avoid while receiving FOLITRAX 20MG INJECTION?

A

It is recommended to avoid the consumption of drinks containing caffeine, such as black tea, coffee, and soft drinks, along with FOLITRAX 20MG INJECTION, to manage dehydration.

Article Information

DW

Written By

DETAILS Written By Dr. N. Sai Swaroop

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

05 Feb 2024

Tags

#cancer oncology (448)#generic name methotrexate 20 mg