FEBUTEC 80 Tablet 10's
Key Information
Generic Name
Generic Name Febuxostat 80 mg
Manufacturer
Cipla Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
FEBUTEC 80 TABLET contains Febuxostat, which belongs to a group of medicines called Antigout agents. It is used in the management of gout (common and complex form of arthritis that occurs when too much uric acid crystallises and deposits in the joints, resulting in sudden, severe attacks of pain, swelling, redness and tenderness in one or more joints, most often in the big toe). It is also used to manage accumulation of high blood levels of uric acid in the blood. Before taking FEBUTEC 80 TABLET inform your doctor if you have any liver, kidney, heart, thyroid problems and undergoing management for Lesch-Nyhan syndrome. FEBUTEC 80 TABLET is not recommended for use by pregnant women, breastfeeding mothers, children, and adolescents. FEBUTEC 80 TABLET should be used with caution by elderly patients. The common
Uses
OF FEBUTEC 80 TABLET Manage gout Prevents accumulation of high uric acid levels in the blood
How It Works
FEBUTEC 80 TABLET works by blocking the action of enzyme called xanthine oxidase, which is involved in the process of converting hypoxanthine into uric acid (purine metabolism pathway). This type of action reduces high uric acid level in gout and blood cancer patients undergoing chemotherapy management.
Directions for Use
Take FEBUTEC 80 TABLET as advised by your physician. Swallow FEBUTEC 80 TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight.
Side Effects
taking FEBUTEC 80 TABLET are abnormal liver test results, diarrhoea, headache, rash, nausea, increase in gout symptoms, localized swelling due to retention of fluids in tissues (oedema). Consult your doctor immediately if any of your symptoms gets worse. USES OF FEBUTEC 80 TABLET Manage gout Prevents accumulation of high uric acid levels in the blood HOW FEBUTEC 80 TABLET WORKSFEBUTEC 80 TABLET works by blocking the action of enzyme called xanthine oxidase, which is involved in the process of converting hypoxanthine into uric acid (purine metabolism pathway). This type of action reduces high uric acid level in gout and blood cancer patients undergoing chemotherapy management. DIRECTIONS FOR USETake FEBUTEC 80 TABLET as advised by your physician. Swallow FEBUTEC 80 TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight. SIDE EFFECTS OF FEBUTEC 80 TABLETCOMMON liver function test results appear abnormal diarrhea headache skin rash nausea exaggerated gout symptoms oedema UNCOMMON decreased appetite signs of diabetes (blood sugar level changes, excessive thirst, increased blood fat levels and weight) loss of sex drive difficulty in sleeping sleepiness dizziness, numbness, tingling, reduced or altered sensation altered taste sensation, decreased sense of smell abnormal ECG, irregular or rapid heartbeats and palpitation hot flushes (e.g., redness of the face or neck), increased blood pressure cough, shortness of breath, chest discomfort or pain, inflammation of nasal passage and/or throat and bronchitis dry mouth, abdominal pain or wind, heartburn, constipation, vomiting, stomach discomfort skin itching, and small red or purple spots on the skin, covered with small confluent bumps, areas of redness and spots on the skin inflammation of joints usually accompanied by pain, swelling and/or stiffness, blood in the urine, abnormal frequent urination, abnormal urine tests (increased level of proteins in the urine) fatigue, chest pain, chest discomfort stones in gallbladder or bile ducts (cholelithiasis) increase thyroid stimulating hormone (TSH) level blood chemistry changes or abnormal amount of blood cells or platelets kidney stones erectile dysfunction RARE nervousness feeling thirsty ringing sensation in the ears blurred vision, change in vision hair loss ulcers in mouth increased sweating weight decrease, increased appetite, or uncontrolled loss of appetite muscle and/or joint stiffness urgent need to urinate changes or decrease in urine amount due to inflamed kidneys inflamed liver, yellowing of the skin or liver damage increased level of creatine phosphokinase in blood sudden cardiac death Stop taking FEBUTEC 80 TABLET and contact your doctor immediately if you experience any of the following side effects: signs of Stevens- Johnson syndrome/ toxic epidermal necrolysis (serious skin rashes characterized by formation of blisters and shedding of the skin and inner surfaces of mouth and genitals, painful ulcers in the mouth and/or genital areas, accompanied by fever, sore throat, fatigue) muscle pain, tenderness, or weakness sings of drug reaction with eosinophilia and systemic symptoms (extensive skin rash in association with enlarged lymph nodes, liver enlargement, raising of the white cells count)
Warnings & Precautions
& PRECAUTIONSPREGNANCYFEBUTEC 80 TABLET is generally not recommended for use by pregnant women. Consult your doctor before taking the medicine. BREASTFEEDINGFEBUTEC 80 TABLET is generally not recommended for use by breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy, sleepy, blurred vision and numbness or tingling sensation after taking FEBUTEC 80 TABLET. KIDNEYFEBUTEC 80 TABLET should be used with caution in patients with having or have had kidney disease. Consult your doctor for advice before taking FEBUTEC 80 TABLET. LIVERFEBUTEC 80 TABLET should be used with caution in patients who have or had liver disease or liver function test abnormalities. Consult your doctor for advice before taking FEBUTEC 80 TABLET. ALLERGYFEBUTEC 80 TABLET is not recommended for use if you are allergic to febuxostat. It should also be used with caution in patients having history of serious allergic reaction to Allopurinol. HEART DISEASEFEBUTEC 80 TABLET should be used with caution in patients having or have had heart failure or heart problems or stroke. Consult your doctor for advice before taking FEBUTEC 80 TABLET. OTHERSBefore taking FEBUTEC 80 TABLET, inform your doctor if you: are being managed for Lesch-Nyhan syndrome have thyroid problems Use in Paediatrics: FEBUTEC 80 TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking FEBUTEC 80 TABLET. Use in Geriatrics: FEBUTEC 80 TABLET should be used with caution in elderly patients. Consult your doctor for advice before taking FEBUTEC 80 TABLET.
Drug Interactions
SA. Drug-Drug Interactions: Before taking FEBUTEC 80 TABLET, inform your doctor if you are taking any of the following medicine: mercaptopurine (used to manage cancer) azathioprine (used to reduce immune response) theophylline (used to manage asthma) Overdosage: If you or anyone else accidentally takes too much of FEBUTEC 80 TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Febuxostat Pharmacological Category : Xanthine oxidase inhibitors Therapeutic Indication : Gout, blood cancer patients undergoing chemotherapy Dosage Forms : Tablet MORE INFORMATION Keep the medicine out of reach from children Store FEBUTEC 80 TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
08 Oct 2022