Falcinil Lfx Tablet 6'S
Key Information
Generic Name
Generic Name Artemether 80 mg+Lumefantrine 480 mg
Manufacturer
Zuventus Healthcare Ltd
Variant
6 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
FALCINIL LFX TABLET is a combination of Artemether and Lumefantrine which belongs to the group of medicines called Antimalarials. It is used in infants, children and adults for the management of acute uncomplicated malaria (mosquito borne disease with symptoms of fever with chills, tiredness, nausea, vomiting, stomach pain) caused by a parasite called plasmodium falciparum. FALCINIL LFX TABLET should be used with caution in patients with severe liver or kidney problems or if the patient feels worse or unwell to eat and drink. FALCINIL LFX TABLET is not recommended for use in patients having severe type of malarial infection affecting the lungs, kidney or brain, heart condition such as changes in the heart rhythm, slow heartbeat or severe heart disease and low levels of electrolytes such as potassium or magnesium in the blood. FALCINIL LFX TABLET is generally not recommended for use during the first trimester of pregnancy and it should be used with caution during the second and third trimester of pregnancy and breast-feeding women only if advised by the doctor. FALCINIL LFX TABLET should be used with caution in children and your child’s doctor may adjust the dose depending upon child’s age and body weight. The most common
Uses
OF FALCINIL LFX TABLET Manage acute uncomplicated malarial infections (caused by plasmodium falciparum) in infants, children and adults
How It Works
FALCINIL LFX TABLET effectively manages malarial infections, where artemether effectively kills the malarial parasites by binding to haem (part of molecules that contains iron which is toxic to malarial parasites) which is produced during the breakdown of haemoglobin. Lumefantrine works by binding to hemin where it manages the formation of a toxic malarial pigment called hemozoin, thereby it manages malarial infection. In addition to this artemether and lumefantrine blocks nucleic acid and protein synthesis in parasite that damages the parasitic cell membrane of plasmodium falciparum which leads to the death of parasite. Thus, it helps in managing the malarial infection.
Directions for Use
Take FALCINIL LFX TABLET exactly as advised by your doctor. For Tablet, Capsule: Swallow FALCINIL LFX TABLET with a glass of water. This medicine should be taken with food or drinks rich in fat such as milk. Crush the medicine into powder if your child is unable to swallow the whole medicine. For Dispersible Tablet: Disperse FALCINIL LFX TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the disease condition.
Side Effects
taking FALCINIL LFX TABLET are headache, dizziness, vomiting, stomach pain, nausea, muscle pain and loss of appetite. Consult your doctor if any of the side effects worsen. USES OF FALCINIL LFX TABLET Manage acute uncomplicated malarial infections (caused by plasmodium falciparum) in infants, children and adults HOW FALCINIL LFX TABLET WORKSFALCINIL LFX TABLET effectively manages malarial infections, where artemether effectively kills the malarial parasites by binding to haem (part of molecules that contains iron which is toxic to malarial parasites) which is produced during the breakdown of haemoglobin. Lumefantrine works by binding to hemin where it manages the formation of a toxic malarial pigment called hemozoin, thereby it manages malarial infection. In addition to this artemether and lumefantrine blocks nucleic acid and protein synthesis in parasite that damages the parasitic cell membrane of plasmodium falciparum which leads to the death of parasite. Thus, it helps in managing the malarial infection. DIRECTIONS FOR USETake FALCINIL LFX TABLET exactly as advised by your doctor. For Tablet, Capsule: Swallow FALCINIL LFX TABLET with a glass of water. This medicine should be taken with food or drinks rich in fat such as milk. Crush the medicine into powder if your child is unable to swallow the whole medicine. For Dispersible Tablet: Disperse FALCINIL LFX TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the disease condition. SIDE EFFECTS OF FALCINIL LFX TABLETCOMMON headache, dizziness nausea, vomiting stomach pain diarrhea muscle or joint pain difficulty to sleep loss of appetite cough fast heartbeat general weakness, tiredness involuntary muscle spasms abnormal walking (in children above 12 years) tingling sensation or numbness of hand and feet rashes or itching in the skin disturbance in heart rhythm (prolonged QTc interval) UNCOMMON sleepiness decreased skin sensitivity inability to coordinate movements RARE allergic reactions Stop taking FALCINIL LFX TABLET and contact your doctor immediately if you experience any of the following side effects: swelling of the face, lips, tongue or throat with difficulty in breathing and swallowing skin condition with large fluid filled blisters (bullous eruption)
Warnings & Precautions
& PRECAUTIONSPREGNANCYFALCINIL LFX TABLET is generally not recommended for use during the first trimester of pregnancy. It should be used with caution during second and third trimester of pregnancy only if considered clearly necessary. Consult your doctor before taking FALCINIL LFX TABLET. BREASTFEEDINGFALCINIL LFX TABLET should be taken with caution in breast feeding women only if considered clearly necessary. Consult your doctor before taking FALCINIL LFX TABLET. DRIVING AND USING MACHINESDo not drive or operate any machines if you experience dizziness, sleepiness or weakness after taking FALCINIL LFX TABLET. KIDNEYFALCINIL LFX TABLET is not recommended for use in patients having severe type of malarial infection affecting the kidneys. It should be taken with caution in patients with severe kidney problems. Consult your doctor before taking FALCINIL LFX TABLET. LIVERFALCINIL LFX TABLET should be taken with caution in patients with severe liver problems. Consult your doctor before taking FALCINIL LFX TABLET. ALLERGYDo not take FALCINIL LFX TABLET if you are allergic to Artemether, Lumefantrine or any other ingredients of this medicine. LUNGSFALCINIL LFX TABLET is not recommended for use in patients having malaria with pulmonary edema or severe type of malarial infection affecting the lungs. Consult your doctor before taking it. HEART DISEASEFALCINIL LFX TABLET is not recommended for use in patients with severe heart disease or with heart diseases such as slow heartbeat, changes in the rhythm or rate of the heartbeat or family history of death due to heart problems or born with heart problems. FALCINIL LFX TABLET should be taken with caution in patients with variations in ECG (prolongation of QTc interval). Consult doctor before taking FALCINIL LFX TABLET. OTHERSFALCINIL LFX TABLET is not recommended for use if you have: severe type of malarial infection that has affected the brain low levels of electrolytes such as potassium or magnesium in blood Before taking FALCINIL LFX TABLET, inform your doctor if you: infected with both the plasmodium falciparum and plasmodium vivax parasites feeling worse or if you feel too unwell to eat and drink Use in pediatrics FALCINIL LFX TABLET should be given with caution in children as the dosages of FALCINIL LFX TABLET vary in children according to their body weight. So, consult a paediatrician before you give this medicine to your child. Use in geriatrics FALCINIL LFX TABLET can be used in elderly patients. However, consult your doctor before taking this medicine.
Drug Interactions
SA. Drug – drug interactions: Before taking FALCINIL LFX TABLET, inform your doctor if you are taking any of the following medicines: medicines used to manage heart rhythm problems (Ex. Flecainide, metoprolol) medicines used to manage depression (Ex. imipramine, amitriptyline, clomipramine, St. John’s wort) medicine used to manage leprosy or tuberculosis (Ex. rifampicin) medicines used to manage bacterial infections (EX. fluroquinolones such as ciprofloxacin, levofloxacin, macrolide antibiotics like azithromycin, erythromycin) medicines used to manage fungal infection (Ex. ketoconazole, fluconazole, itraconazole) medicines used to manage allergy (Ex. terfenadine, astemizole) medicine used to manage stomach disturbance (Ex. cisapride) medicines used to manage fits (Ex. carbamazepine, phenytoin) medicines used to manage malaria (Ex. atovaquone/proguanil, chloroquine) medicines used to manage HIV infection (Ex. indinavir, ritonavir) medicine used to manage pregnancy (Ex. Ethinyl estradiol) B. Drug – Food interactions Drink grapefruit juice with caution while taking FALCINIL LFX TABLET as it may interact with this medicine. Overdosage: If you or anyone else accidentally take too much of FALCINIL LFX TABLET, consult your doctor immediately or visit a nearby hospital. SYNOPSIS Drug : Artemether, Lumefantrine Pharmacological Category : Antimalarials Therapeutic Indication : Manages acute uncomplicated malaria Dosage Forms : Tablet, Dispersible tablet, Injection, Syrup, Oral suspension, Dry Syrup MORE INFORMATION Keep FALCINIL LFX TABLET out of reach of children Store FALCINIL LFX TABLET at room temperature
Article Information
Written By
ity (FDA).[Revised in February 2018] [Accessed on 3rd November 2022] https://fdaghana.gov.gh/img/smpc/Artefan%20(Artemether
Medical Content Writer
Last Updated
12 Nov 2022