Espin TM Tablet 10'S
Key Information
Generic Name
Generic Name S(-)Amlodipine 2.5 mg+Telmisartan 40 mg
Manufacturer
Intas Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ESPIN TM TABLET is a combination of S(-)Amlodipine and Telmisartan which belongs to the group of medicines called Antihypertensive agents. It is used in adults to manage hypertension (high blood pressure) when management with single agents is not effective. Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several vital organs, such as heart, kidney, or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness. By lowering blood pressure, ESPIN TM TABLET can also reduce the risk of heart attack (myocardial infarction) or stroke. It can also be used to manage angina pectoris (chest pain caused due to low oxygen supply). During management with ESPIN TM TABLET your doctor will constantly monitor your kidney functions, blood pressure and blood sugar levels to avoid the risk of unwanted
Uses
OF ESPIN TM TABLET Manage Hypertension (high blood pressure) Manage Angina (chest pain) Prevents the risk of heart attack or stroke
How It Works
ESPIN TM TABLET effectively controls blood pressure in patients with hypertension. It contains two medicines namely, S(-)Amlodipine and telmisartan. Telmisartan blocks the actions of certain hormones (angiotensin-II) in the body that causes narrowing of blood vessels and increase in blood pressure. S(-)Amlodipine is a vasodilator. It relaxes the blood vessels by blocking the entry of certain ions (calcium ions) within them that causes narrowing. This allows blood to flow more smoothly across the blood vessels. Collectively, they reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.
Directions for Use
Take ESPIN TM TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take ESPIN TM TABLET at the same time each day. ESPIN TM TABLET can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take ESPIN TM TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.
Side Effects
taking ESPIN TM TABLET are low blood pressure, dizziness, tiredness, headache, sleepiness, swollen ankles, and flushing. Contact your doctor if any of these side effect worsens. USES OF ESPIN TM TABLET Manage Hypertension (high blood pressure) Manage Angina (chest pain) Prevents the risk of heart attack or stroke HOW ESPIN TM TABLET WORKSESPIN TM TABLET effectively controls blood pressure in patients with hypertension. It contains two medicines namely, S(-)Amlodipine and telmisartan. Telmisartan blocks the actions of certain hormones (angiotensin-II) in the body that causes narrowing of blood vessels and increase in blood pressure. S(-)Amlodipine is a vasodilator. It relaxes the blood vessels by blocking the entry of certain ions (calcium ions) within them that causes narrowing. This allows blood to flow more smoothly across the blood vessels. Collectively, they reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure. DIRECTIONS FOR USETake ESPIN TM TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take ESPIN TM TABLET at the same time each day. ESPIN TM TABLET can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take ESPIN TM TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results. SIDE EFFECTS OF ESPIN TM TABLETCOMMON low blood pressure swelling of ankles and legs (edema) headache, dizziness nausea, vomiting, stomach pain, constipation, diarrhea, indigestion sleepiness abnormal heartbeat (fast or slow) muscle cramps flushing (warmth and redness of face and neck) feeling tired or weak vision problems UNCOMMON urinary tract infections, difficulty in passing urine, urge to urinate sore throat, common cold high blood potassium levels (causing muscle weakness, irregular heartbeat, chest pain) difficulty in falling asleep feeling depressed or anxious, changes in mood vertigo (spinning sensation), shakiness orthostatic hypotension (dizziness while standing up from sitting or lying position) increased sweating back pain, tingling of numbness of body parts changes in taste ringing in the ears dry nose, dry mouth hair loss impotence (inability to obtain an erection), breast enlargement in men changes in body weight RAREStop taking ESPIN TM TABLET and contact your doctor immediately if you experience any of the following side effects such as: signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing) severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane) chest pain, shortness of breath inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body) sepsis (infection of blood characterized by sever signs of illness and fever)
Warnings & Precautions
& PRECAUTIONSPREGNANCYESPIN TM TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking ESPIN TM TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with ESPIN TM TABLET, stop taking it and consult your doctor immediately. BREASTFEEDINGESPIN TM TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking ESPIN TM TABLET. ALCOHOLAvoid consumption of alcohol while taking ESPIN TM TABLET as it might make you feel dizzier and drowsier. KIDNEYESPIN TM TABLET should be used with caution in patients with kidney problems (such as kidney transplant, narrowing of renal arteries). Therefore, consult your doctor before taking it. LIVERESPIN TM TABLET is not recommended for use in patients with severe liver impairment (such as cholestasis, jaundice, biliary obstruction). It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it. ALLERGYDo not take ESPIN TM TABLET if you are allergic to S(-)Amlodipine or Telmisartan. HEART DISEASEESPIN TM TABLET should be used with caution in patients with heart problems (such as irregular heart rhythm, heart failure, recent heart attack, and problems with heart muscle or valves). Therefore, consult your doctor before taking it. OTHERSESPIN TM TABLET is not recommended for use if you: have cardiogenic shock (heart cannot pump blood suddenly) have diabetes related kidney problems Before taking ESPIN TM TABLET, inform your doctor if you: have primary hyperaldosteronism (problems in adrenal gland) have low blood pressure or are severely dehydrated (due to diarrhea, vomiting or excess sweating) have diabetes have hyperkalemia (high blood potassium levels) have unstable angina (a type of chest pain) have narrowing of arteries Use in pediatrics: ESPIN TM TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice. Use in geriatrics: ESPIN TM TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug-Drug interactions: Before taking ESPIN TM TABLET, inform your doctor if you are taking any of the following medicines such as: other medicines used to manage elevated blood pressure (such as aliskiren, captopril, enalapril, lisinopril, verapamil, diltiazem, losartan, valsartan) lithium, St. John’s wort (medicines used to manage depression) potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body) non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, celecoxib, ibuprofen, aspirin heparin (a medicine used to manage or manage blood clots) medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, trimethoprim) medicines to suppress immune system (Ex. cyclosporin, tacrolimus, sirolimus, temsirolimus and everolimus) dantrolene (a medicine used to manage muscle spasm) medicine used to manage HIV infection (Ex. indinavir, ritonavir, saquinavir) medicines used to manage fungal infections (Ex. itraconazole, ketoconazole and fluconazole) digoxin (a medicine used to manage irregular heartbeat) simvastatin (a medicine used to lower blood cholesterol levels) baclofen (a medicine used for relaxing muscles) amifostine (a kidney protectant used along with chemotherapeutic agents) medicines used to manage mental disorders such as depression, psychosis, or anxiety (Ex. pimozide, amisulpride, haloperidol) corticosteroids (used to manage inflammation) Ex. prednisolone B. Drug-Food interactions: Do not eat grapefruit or drink grapefruit juice while taking ESPIN TM TABLET as it may increase the risk of side effects. Overdosage: If you or anyone else accidentally took more ESPIN TM TABLET, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, and dizziness. SYNOPSIS Drug : S(-)Amlodipine, Telmisartan Pharmacological Category : Calcium channel blocker, Angiotensin II Receptor Blocker Therapeutic Indication : Hypertension, Angina, Prevention of Heart Attack or Stroke Dosage Forms : Tablet MORE INFORMATION Keep ESPIN TM TABLET out of reach of children Store ESPIN TM TABLET at room temperature
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
18 Oct 2022