Erlocip 100mg Tablet 30'S
Key Information
Generic Name
Generic Name Erlotinib 100 mg
Manufacturer
Cipla Ltd
Variant
30 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ERLOCIP 100MG TABLET contains Erlotinib which belongs to the group of medicines called Kinase inhibitors. It is used in adults to manage non-small cell lung cancer at an advanced stage, as initial therapy (or as therapy if disease remains largely unchanged after initial chemotherapy, provided your cancer cells have specific EGFR mutations). It is also used if previous chemotherapy has not helped to stop the disease and to manage cancer of the pancreas at a metastatic stage in combination with gemcitabine. Cancer can be defined as body cells beginning to grow out of control. Cells in any part of the body can become cancer cells and can spread to other areas of the body. Your doctor may perform certain blood tests prior to the management. Avoid smoking during the management of ERLOCIP 100MG TABLET, as it decreases the effect of the medicine. ERLOCIP 100MG TABLET is not recommended for use if you have severe liver or kidney disease. Before taking ERLOCIP 100MG TABLET inform your doctor if you have diarrhea, glucuronidation disorder like Gilbert’s syndrome, history of peptic ulcers or diverticular disease, you use contact lenses, or have a history of eye problems (severe dry eyes, inflammation or ulcers of the cornea). ERLOCIP 100MG TABLET is generally not recommended for use in pregnant and breastfeeding women unless con
Uses
OF ERLOCIP 100MG TABLETManage: non-small cell lung cancer at an advanced stage initial cancer stage (or as therapy if disease remains largely unchanged after initial chemotherapy) pancreatic cancer at a metastatic stage in combination with gemcitabine
How It Works
ERLOCIP 100MG TABLET binds to the intracellular portion (tyrosine kinase) of the epidermal growth factor receptor (EGFR) and inhibits its activity. EGFR is expressed on the surface of both normal as well as cancer cells. Inhibition of EGFR and its signaling significantly decreases tumor multiplication and survival, resulting in cell death.
Directions for Use
Take ERLOCIP 100MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not take medicine with food. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects
taking ERLOCIP 100MG TABLET are rash, infection, loss of appetite, decreased weight, or depression. Contact your doctor if any of the symptoms worsen. USES OF ERLOCIP 100MG TABLETManage: non-small cell lung cancer at an advanced stage initial cancer stage (or as therapy if disease remains largely unchanged after initial chemotherapy) pancreatic cancer at a metastatic stage in combination with gemcitabine HOW ERLOCIP 100MG TABLET WORKSERLOCIP 100MG TABLET binds to the intracellular portion (tyrosine kinase) of the epidermal growth factor receptor (EGFR) and inhibits its activity. EGFR is expressed on the surface of both normal as well as cancer cells. Inhibition of EGFR and its signaling significantly decreases tumor multiplication and survival, resulting in cell death. DIRECTIONS FOR USETake ERLOCIP 100MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not take medicine with food. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF ERLOCIP 100MG TABLETCOMMON rash which may occur or worsen in sun-exposed areas infection loss of appetite, decreased weight depression headache change in skin sensation or numbness in the extremities difficulty in breathing, cough nausea mouth irritation stomach pain, indigestion, and flatulence itching, dry skin loss of hair tiredness, fever, rigor bleeding from the nose, stomach, or the intestines inflammatory reactions around the fingernail infection of hair follicles acne cracked skin (skin fissures) reduced kidney function UNCOMMON eyelash and eyebrow changes excess hair in the body and face of a male distribution pattern brittle and loose nails RARE palmar plantar erythrodysaesthesia syndrome (flushed or painful palms or soles) Stop taking ERLOCIP 100MG TABLET and contact your doctor immediately if you experience any of the following side effects: persistent and severe diarrhea and vomiting eye irritation due to conjunctivitis/keratoconjunctivitis or keratitis interstitial lung disease (sudden difficulty breathing associated with cough or fever) gastrointestinal perforations (severe pain in the abdomen) acute or worsening redness and pain in the eye increased water in the eye, blurred vision, and/or sensitivity to light blistering or peeling of skin inflammation of the liver ( feeling of being unwell, with or without jaundice (yellowing of the skin and eyes), dark urine, nausea, vomiting and abdominal pain)
Warnings & Precautions
& PRECAUTIONSPREGNANCYThere is no adequate data on the use of ERLOCIP 100MG TABLET in pregnant women. If you become pregnant during the management immediately inform your doctor who will decide if the management should be continued. Use adequate contraception during management, and for at least 2 weeks after taking the last medicine. Consult your doctor before taking ERLOCIP 100MG TABLET. BREASTFEEDINGERLOCIP 100MG TABLET is not recommended for use in breastfeeding women and for at least 2 weeks after taking the last medicine. Consult your doctor before taking ERLOCIP 100MG TABLET. DRIVING AND USING MACHINESERLOCIP 100MG TABLET is unlikely to affect your ability to drive or use machines. KIDNEYERLOCIP 100MG TABLET is generally not recommended to use in patients with severe kidney disease. Consult your doctor before taking ERLOCIP 100MG TABLET. LIVERERLOCIP 100MG TABLET is generally not recommended to use in patients with severe liver disease. Consult your doctor before taking ERLOCIP 100MG TABLET. ALLERGYDo not take ERLOCIP 100MG TABLET if you are allergic to Erlotinib or any of the other ingredients of the medicines. OTHERSBefore taking ERLOCIP 100MG TABLET, inform your doctor if you have: contact lenses history of eye problems such as severe dry eyes, inflammation or ulcers of the front part of the eye (cornea) diarrhea history of peptic ulceration or diverticular disease glucuronidation disorder like Gilbert’s syndrome Use in pediatrics: ERLOCIP 100MG TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking ERLOCIP 100MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking ERLOCIP 100MG TABLET, inform your doctor if you are taking any of the following medicine: ketoconazole (to manage fungal infections) erythromycin, clarithromycin, and ciprofloxacin (antibacterial agents) protease inhibitors like atazanavir, idinavir (to manage HIV) warfarin (to manage blood clotting) statins (Ex. atorvastatin, rosuvastatin, simvastatin) to lower blood cholesterol phenytoin, carbamazepine (manages epilepsy or fits) omeprazole, ranitidine (reduces stomach acid) rifampicin (manages tuberculosis) St. John’s Wort (manages depression) barbiturates (used to manage seizures) Overdosage: If you or anyone else accidentally takes too much ERLOCIP 100MG TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Erlotinib Pharmacological Category : Kinase inhibitors Therapeutic Indication : Non-small cell lung cancer, initial cancer therapy and pancreatic cancer Dosage Forms : Tablet MORE INFORMATION Keep ERLOCIP 100MG TABLET out of reach of children Store at room temperature
Article Information
Written By
DETAILS Written By Dr. Shruthi M R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
10 Jan 2023