Eptoin Injection 2ml
Key Information
Generic Name
Generic Name Phenytoin 100 mg
Manufacturer
Abbott India Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT EPTOIN INJECTIONEPTOIN INJECTION contains phenytoin which belongs to the group of medicines called Anti-epileptic drugs. It is used to manage certain forms of epilepsy (fits or seizures) like grand mal fits, status epilepticus (seizures continue for hours or days) and to manage fits during or after neurosurgery. Epilepsy can be defined as a chronic brain disorder which occurs when signals and chemicals of the brain cells are not working properly. EPTOIN INJECTION can also be used to rectify some heart rhythm abnormalities. During EPTOIN INJECTION management, your doctor might ask you to take certain blood tests to monitor
Uses
OF EPTOIN INJECTIONEPTOIN INJECTION is used to: manage grand mal fits and status epilepticus prevent fits during or after neurosurgery rectify some heart rhythm abnormalities
How It Works
EPTOIN INJECTION reduces or manages fits by controlling the hyperactivity in the brain that can cause epilepsy or fits.
Directions for Use
EPTOIN INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the right dose and duration for you according to your age, body weight and disease condition. Do not stop receiving EPTOIN INJECTION unless your doctor advises you to stop.
Side Effects
alcohol while receiving EPTOIN INJECTION as it may affect its blood concentration. Ask your doctor before receiving EPTOIN INJECTION during pregnancy. EPTOIN INJECTION should be used in breastfeeding women only if the potential benefit justifies the potential risk to the foetus. EPTOIN INJECTION should be cautiously used in children and elderly patients. The most common side effects of receiving EPTOIN INJECTION are rapid involuntary eye movements, slurred speech, impaired or decreased coordination, sleepiness and mental confusion. Contact your doctor if any of the symptoms deteriorate. USES OF EPTOIN INJECTIONEPTOIN INJECTION is used to: manage grand mal fits and status epilepticus prevent fits during or after neurosurgery rectify some heart rhythm abnormalities HOW EPTOIN INJECTION WORKSEPTOIN INJECTION reduces or manages fits by controlling the hyperactivity in the brain that can cause epilepsy or fits. DIRECTIONS FOR USEEPTOIN INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the right dose and duration for you according to your age, body weight and disease condition. Do not stop receiving EPTOIN INJECTION unless your doctor advises you to stop. SIDE EFFECTS OF EPTOIN INJECTIONCOMMON nystagmus (rapid involuntary eye movements) slurred speech impaired or decreased coordination sleepiness mental confusion RARE serious forms of allergic reactions Drug Reaction with Eosinophilia and Systemic Symptoms (an extensive skin rash) angioedema (swelling beneath the skin) dyskinesias (impaired voluntary movement), including chorea (jerky involuntary movements of the shoulders, hips and face), dystonia (muscular spasm and abnormal posture), shaking and asterixis (inability to maintain sustained posture with subsequent brief jerky involuntary movements) certain types of dermatitis Stop receiving EPTOIN INJECTION and contact your doctor immediately if you experience any of the following side effects: severe allergic reactions (swelling of the eyelids, face, lips, rash or itching especially affecting the whole body, breathing problems, sudden wheeziness) purple glove syndrome (discolouration of the skin, swelling and pain in the area of injection which then radiates down to the arms, hands and fingers) serious skin reactions (Ex. Stevens-Johnson syndrome, toxic epidermal necrolysis accompanied by blistering of mouth and tongue) blood abnormalities (bruising, fever, severe sore throat, paleness, decreased red blood cells, white cells and platelets) hypersensitivity reactions (skin rash, fever, swollen glands, increased white blood cells, swollen organs such as liver, lungs, heart, kidneys and large intestine) inflammatory disease called systemic lupus erythematosus (painful and swollen joints) have confusion or mental illness which could be a sign of a high amount of medicine in the blood chest pains and palpitations swollen lymph nodes thoughts of harming or killing self
Warnings & Precautions
& PRECAUTIONSPREGNANCYEPTOIN INJECTION should be used with caution in pregnant women as it may cause harm to the unborn baby. Women of childbearing capability should use a suitable non-hormonal contraceptive method to avoid getting pregnant while receiving EPTOIN INJECTION. Consult your doctor before receiving it. Inform your doctor if you become pregnant during management with EPTOIN INJECTION. BREASTFEEDINGEPTOIN INJECTION should be used in breastfeeding women only if the potential benefit justifies the potential risk to the foetus. Consult your doctor before receiving it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy or drowsy after receiving EPTOIN INJECTION. ALCOHOLAvoid consumption of alcohol while receiving EPTOIN INJECTION because it may reduce the effectiveness of management or increase the side effects. EPTOIN INJECTION should be used with caution if the patient has consumed a large amount of alcohol recently or if they drink large amounts of alcohol regularly or if they have alcohol dependence. Consult your doctor before receiving it. KIDNEYEPTOIN INJECTION should be used with caution in patients having kidney disease. Consult your doctor before receiving it. LIVEREPTOIN INJECTION is not recommended for use in patients who experienced prior acute liver toxicity due to phenytoin. EPTOIN INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving it. ALLERGYDo not receive EPTOIN INJECTION if you are allergic to Phenytoin or any of the other ingredients of this medicine or similar hydantoins such as ethotoin or methoin. HEART DISEASEEPTOIN INJECTION is not recommended in patients having abnormal heart rhythm and heart block, a slow heartbeat, heart problems that affect your heart rate or Adams-Stokes syndrome (suddenly passing out due to change in your heart rate). EPTOIN INJECTION should be used with caution in patients having low blood pressure, heart failure or heart rhythm problems. Consult your doctor before receiving it. OTHERSBefore receiving EPTOIN INJECTION, inform your doctor if you have: porphyria (an inherited disease affecting the nervous system and skin, characterised by abdominal pain, vomiting or muscle weakness) diabetes (high blood sugar levels) Use in paediatrics: EPTOIN INJECTION can be used for newborns, infants and children but consult your child’s doctor for advice. Use in geriatrics: EPTOIN INJECTION should be used with caution in elderly patients. Consult your doctor before receiving it.
Drug Interactions
SA. Drug - Drug interactions: Before receiving EPTOIN INJECTION, inform your doctor if you are taking any of the following medicines: medicines used for epilepsy or fits (Ex. carbamazepine, lamotrigine, phenobarbital, sodium valproate and valproic acid, topiramate, oxcarbazepine, ethosuximide,vigabatrin) medicines used to manage fungal infections (Ex. amphotericin B, voriconazole, miconazole, fluconazole, itraconazole, ketoconazole, posaconazole) medicines used to manage skin diseases (Ex. methoxsalen) medicines used for tuberculosis and other infections (Ex. chloramphenicol, isoniazid, rifampicin, sulfadiazine, sulfamethizole, sulfamethoxazole-trimethoprim, sulfaphenazole, sulfisoxazole, doxycycline, ciprofloxacin) medicines used for asthma and bronchitis (Ex. theophylline) medicines used for diabetes (Ex. tolbutamide, insulin) medicines used for pain and inflammation (Ex. phenylbutazone, aspirin, prednisolone) medicines used for stomach ulcers and heartburn (Ex. omeprazole, sucralfate, cimetidine, ranitidine, famotidine, antacids) medicines used for sleeplessness, depression and psychiatric disorders (Ex. chlordiazepoxide, clozapine, diazepam, disulfiram, lithium, methadone, fluoxetine, fluvoxamine, sertraline, haloperidol, levodopa, paroxetine, methylphenidate, phenothiazines, quetiapine, trazodone, reserpine, amitriptyline, viloxazine) medicines used to manage cancer (Ex. teniposide, fluorouracil, doxorubicin, methotrexate, capecitabine, bleomycin, carboplatin, cisplatin) medicines used for organ and tissue transplants, to manage rejection (Ex. ciclosporin, tacrolimus) medicines used for heart and circulation problems (Ex. dicoumarol, amiodarone, digitoxin, digoxin, nisoldipine, disopyramide, mexiletine, furosemide, quinidine, reserpine, diltiazem, nifedipine) hormone replacement therapies (Ex. oestrogens) medicines used to manage pregnancy (Ex. estradiol, dienogestrel) medicines used to lower high blood cholesterol and triglycerides (Ex. atorvastatin, fluvastatin, simvastatin) medicines used in the management of HIV infection (Ex delavirdine, efavirenz, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir) medicines used to expel parasitic worms from the body (Ex. albendazole, praziquantel) medicines used to manage thyroid disorders (Ex. thyroxine) medicines used to relax the muscles (Ex. pancuronium, rocuronium, vecuronium) medicine used to manage severe pain (Ex. methadone, halothane) non-prescription medicines (Ex. folic acid, St John’s Wort, vitamin D) medicines used for blood thinning (Ex. warfarin, dicoumarol) Overdosage: EPTOIN INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms like nystagmus (involuntary eye movement), double vision, loss of control of the whole body, dysarthria (speech disorder), muscle spasms, lethargy, nausea and vomiting. SYNOPSIS Drug : Phenytoin Pharmacological Category : Anti-epileptic drugs Therapeutic Indication : Seizures (fits) Dosage Forms : Injection, Tablet, Capsule, Syrup, Suspension MORE INFORMATION Keep EPTOIN INJECTION out of reach of children Store EPTOIN INJECTION below 30°C
Article Information
Written By
DETAILS Written By Dr. Jeenal Rajani
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
11 Oct 2022