Entacom Plus 50mg Tablet 10'S

Parkinsonism (115)Rx required

Key Information

Generic Name

Generic Name Carbidopa 12.5 mg+Entacapone 200 mg+Levodopa 50 mg

Manufacturer

Intas Pharmaceuticals Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

ENTACOM PLUS 50MG TABLET is a combination of Carbidopa, Levodopa and Entacapone, which belongs to the group of medicines called Anti-parkinsonian drugs. It is used in the management of Parkinson’s disease. Parkinson's disease is a disorder affecting the brain, causing unintended or uncontrollable movements, such as shaking, stiffness and difficulty along with balance and coordination. It usually starts gradually and worsens over time. As the disease progresses, people have difficulty walking and talking. While taking ENTACOM PLUS 50MG TABLET for the long term, your doctor may suggest some regular laboratory tests. ENTACOM PLUS 50MG TABLET is not recommended for use in patients with severe liver disease, narrow-angle glaucoma, adrenal gland tumour, history of neuroleptic malignant syndrome and non-traumatic rhabdomyolysis. Before taking ENTACOM PLUS 50MG TABLET, inform your doctor if you have asthma or any other disease of the lungs, kidney, heart and mental health diseases. ENTACOM PLUS 50MG TABLET is generally not recommended for use in pregnant women, breastfeeding, children and adolescents (below 18 years of age). The common

Uses

OF ENTACOM PLUS 50MG TABLET Manage Parkinson’s disease

How It Works

ENTACOM PLUS 50MG TABLET is a combination of Levodopa which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa manages the breakdown of Levodopa by allowing it to enter the brain for increased dopamine levels and Entacapone maintains the level of levodopa in the blood. All these collective actions provide greater relief from the symptoms of Parkinson’s disease.

Directions for Use

Take ENTACOM PLUS 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration for you will be decided by your doctor, depending on your age, body weight and disease condition. Do not stop taking ENTACOM PLUS 50MG TABLET without your doctor’s advice.

Side Effects

ENTACOM PLUS 50MG TABLET are uncontrolled movements, nausea, reddish-brown, discoloured urine, diarrhoea and muscle pain. If any of these become worse, contact your doctor. USES OF ENTACOM PLUS 50MG TABLET Manage Parkinson’s disease HOW ENTACOM PLUS 50MG TABLET WORKSENTACOM PLUS 50MG TABLET is a combination of Levodopa which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa manages the breakdown of Levodopa by allowing it to enter the brain for increased dopamine levels and Entacapone maintains the level of levodopa in the blood. All these collective actions provide greater relief from the symptoms of Parkinson’s disease. DIRECTIONS FOR USETake ENTACOM PLUS 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration for you will be decided by your doctor, depending on your age, body weight and disease condition. Do not stop taking ENTACOM PLUS 50MG TABLET without your doctor’s advice. SIDE EFFECTS OF ENTACOM PLUS 50MG TABLETCOMMON uncontrolled movements nausea and vomiting reddish-brown discoloured urine diarrhoea muscle pain and cramps light-headedness or fainting due to changes in blood pressure dizziness, drowsiness and tiredness abdominal pain and discomfort, heartburn, dry mouth, constipation inability to sleep, abnormal dreams (including nightmares) mental confusion and seeing or feeling imaginary things memory problems, anxiety and depression (possibly suicidal thoughts) chest pain, irregular heart rate or rhythm more frequent falling pallor skin and shortness of breath increased sweating and skin rashes swelling of legs blurred vision weight loss headache, joint pain pelvic pain, increased urge to urinate, irritation while urinating and blood in the urine UNCOMMON tightness or pain in the chest, which spreads to the neck, back or arms black or tarry stool, blood in vomit and abdominal cramps (signs of gut bleeding) changes in the blood cell count which may result in bleeding, abnormal liver function tests convulsions agitation, disorganised behaviour, restlessness discoloured skin, nails, hair and sweat other than urine swallowing difficulties inability to urinate RARE yellowing of skin or eyes, nausea, abdominal pain, fatigue, fever. dark urine, light-coloured stools itching Stop taking ENTACOM PLUS 50MG TABLET and contact your doctor immediately if you experience any of the following side effects: signs of neuroleptic malignant syndrome or rhabdomyolysis (a rare severe reaction to medicines used to manage disorders of the central nervous system causing your muscles to get very rigid or jerk violently, tremors, agitation, confusion, fever, rapid pulse or wide fluctuations in your blood pressure) signs of an allergic reaction (nettle skin rash, itching, rash, swelling of your face, lips, tongue or throat, causing difficulties in breathing or swallowing) strong impulse to gamble excessively despite serious personal or family consequences altered or increased sexual interest and behaviour uncontrollable excessive shopping or spending eating large amounts of food in a short time or eating more food than needed to satisfy your hunger

Warnings & Precautions

& PRECAUTIONSPREGNANCYENTACOM PLUS 50MG TABLET is generally not recommended for use by pregnant women unless considered necessary. Consult your doctor for advice. BREASTFEEDINGENTACOM PLUS 50MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor for advice. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel light-headed, dizzy, drowsy or suddenly you may fall asleep after taking ENTACOM PLUS 50MG TABLET. KIDNEYENTACOM PLUS 50MG TABLET should be taken with caution in patients with kidney diseases. Consult your doctor for advice. LIVERENTACOM PLUS 50MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver problems. Consult your doctor for advice. ALLERGYDo not take ENTACOM PLUS 50MG TABLET if you are allergic to Levodopa, Carbidopa or Entacapone. LUNGSENTACOM PLUS 50MG TABLET should be taken with caution in patients with asthma or any other disease of the lungs. Consult your doctor for advice. HEART DISEASEENTACOM PLUS 50MG TABLET should be taken with caution in patients experienced a heart attack or any other heart disease including cardiac arrhythmias or of the blood vessels. Consult your doctor for advice. OTHERSENTACOM PLUS 50MG TABLET is not recommended for use if you: have narrow-angle glaucoma (an eye disorder) have adrenal gland tumour have ever had neuroleptic malignant syndrome (a rare reaction to medicines used to manage severe mental disorders) have ever had non-traumatic rhabdomyolysis (a rare muscle disorder) Before taking ENTACOM PLUS 50MG TABLET, inform your doctor if you: have hormone-related diseases have stomach ulcers or convulsions have experienced prolonged diarrhoea have any form of severe mental disorder like psychosis have chronic wide-angle glaucoma are going to undergo surgery Use in Pediatrics: ENTACOM PLUS 50MG TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor for advice. Use in Geriatrics: ENTACOM PLUS 50MG TABLET should be used with caution in elderly patients. Consult your doctor for advice.

Drug Interactions

SA. Drug-Drug interactions: Before taking ENTACOM PLUS 50MG TABLET, inform your doctor if you are taking any of the following medicine: medicines used for managing depression (Ex. combinations of selective MAO-A and MAO-B inhibitors or non-selective MAO inhibitors, moclobemide, amitriptyline, desipramine, maprotiline, venlafaxine and paroxetine rimiterole and isoprenaline (medicines used to manage respiratory diseases adrenaline (a medicine used for severe allergic reactions) noradrenaline, dopamine and dobutamine (medicines used to manage heart diseases and low blood pressure) alpha-methyldopa (a medicine used in managing high blood pressure) other medicine used for managing Parkinson’s disease (Ex. apomorphine) medicines used to manage mental disorders, nausea and vomiting (Ex. chlorpromazine, metoclopramide, promethazine, paliperidone and risperidone) phenytoin (a medicine used to manage convulsions) papaverine (a medicine used to relax the muscles) iron supplements B. Drug-Food interaction: ENTACOM PLUS 50MG TABLET may not be well absorbed if it is taken with or shortly after eating protein-rich foods (meat, fish, dairy products, seeds and nuts). Consult your doctor for advice. Overdosage: If you or anyone else accidentally take too much of ENTACOM PLUS 50MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are mental confusion or agitation, your heart rate may be slower or faster than normal and the colour of your skin, tongue, eyes or urine may change. SYNOPSIS Drug : Carbidopa, Levodopa, Entacapone Pharmacological Category : Decarboxylase inhibitors, central nervous system agents, catechol-O-methyl transferase (COMT) inhibitors Therapeutic Indication : Parkinson’s disease Dosage Forms : Tablet MORE INFORMATION Keep ENTACOM PLUS 50MG TABLET out of reach from children Store at room temperature

Frequently Asked Questions

Common questions and answers about Entacom Plus 50mg Tablet 10'S.

Q

Can I stop taking ENTACOM PLUS 50MG TABLET once I feel better?

A

No, you should not stop taking ENTACOM PLUS 50MG TABLET unless your doctor tells you to. In such a case, your doctor may need to adjust your other medicines to give you sufficient control over your symptoms. If you suddenly stop taking ENTACOM PLUS 50MG TABLET, it may result in unwanted side effects.

Q

What types of foods need to be avoided while taking ENTACOM PLUS 50MG TABLET?

A

You need to avoid eating protein-rich foods (meat, fish, dairy products, seeds and nuts) when taken along with or shortly after taking ENTACOM PLUS 50MG TABLET because it may decrease the absorption of the medicine. If you still have any doubts, consult your doctor for advice.

Q

Does ENTACOM PLUS 50MG TABLET have addictive effects?

A

Yes, ENTACOM PLUS 50MG TABLET may develop addiction-like symptoms leading to a craving for large doses. If you or your family notice signs of developing urges or cravings to behave in unusual ways or if you are unable to resist the impulse, consult your doctor immediately for a review of the management.

Q

Can we use ENTACOM PLUS 50MG TABLET for children?

A

No. ENTACOM PLUS 50MG TABLET is generally not recommended for use in children and adolescents below 18 years of age. Therefore, consult your doctor before taking ENTACOM PLUS 50MG TABLET.

Q

Does ENTACOM PLUS 50MG TABLET cause weight loss?

A

Yes, ENTACOM PLUS 50MG TABLET may cause weakness, exhaustion and weight loss within a relatively short period. If this happens to you, please inform your doctor. The doctor might do a general evaluation, including liver function.

Article Information

DW

Written By

DETAILS Written By Dr. Dhivakaran R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

27 Dec 2022

Tags

#parkinsonism (115)#generic name carbidopa 12.5 mg+entacapone 200 mg+levodopa 50 mg