ENSAME 400 Tablet 10's
Key Information
Generic Name
Generic Name 4 Butanedisulfonate 400 mg+Ademetionine-1
Manufacturer
Icarus Health Care Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ENSAME 400 TABLET contains S-Adenosyl-L-Methionine which belongs to the group of medicines called Amino acid derivatives. It is used to manage liver problems such as intrahepatic cholestasis (ICP; block in bile flow), liver cirrhosis, hepatitis and alcoholic liver disease in adults. It can also be used to manage ICP of pregnancy and can reduce the fatigue caused by chronic liver problems. It also helps to reduce joint pain (osteoarthritis), fibromyalgia (severe muscle pain with memory and mood problems), anxiety, depression and other mental illnesses. Before taking ENSAME 400 TABLET inform your doctor if you have any kidney problems. You must also inform your doctor if you have bipolar disorder or a previous history of suicidal thoughts as a precaution. Vitamins such as folic acid and vitamin B12 are essential to enhance the effects of S-Adenosyl-L-Methionine in your body. Therefore, inform your doctor if you have any vitamin deficiencies or anemia as a precaution. You doctor may advise you to take B-vitamin supplements (folic acid and vitamin B12) along with this medicine. During management with ENSAME 400 TABLET your doctor will routinely monitor the levels of ammonia, folic acid and vitamin B12 in your blood as a precaution and adjust the dose accordingly. Do not take ENSAME 400 TABLET without consulting your doctor if you are pregnant or breastfeeding. The most common
Uses
OF ENSAME 400 TABLETIt is used in adults to manage: intrahepatic cholestasis (ICP) in patients with or without liver disease intrahepatic cholestasis during pregnancy liver diseases (liver cirrhosis, hepatitis and alcoholic liver disease) fatigue caused due to chronic liver problems anxiety, depression and other mental illnesses osteoarthritis (joint pain) fibromyalgia (severe muscle pain causing memory and mood changes)
How It Works
ENSAME 400 TABLET protects your liver against various toxins (free radicals) and helps your liver to function normally. It improves the levels of glutathione (an antioxidant) in the liver which helps in managing further liver cell damage. It also increases the levels of certain chemical messengers (such as dopamine, noradrenaline, adrenaline, serotonin, melatonin) in the brain that can stabilize mood and mental health. It can also reduce the production of certain chemicals in the body that causes pain and inflammation.
Directions for Use
Take ENSAME 400 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. It is preferably taken before meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects
taking ENSAME 400 TABLET are nausea, stomach pain and diarrhea. Consult your doctor if they trouble you. USES OF ENSAME 400 TABLETIt is used in adults to manage: intrahepatic cholestasis (ICP) in patients with or without liver disease intrahepatic cholestasis during pregnancy liver diseases (liver cirrhosis, hepatitis and alcoholic liver disease) fatigue caused due to chronic liver problems anxiety, depression and other mental illnesses osteoarthritis (joint pain) fibromyalgia (severe muscle pain causing memory and mood changes) HOW ENSAME 400 TABLET WORKSENSAME 400 TABLET protects your liver against various toxins (free radicals) and helps your liver to function normally. It improves the levels of glutathione (an antioxidant) in the liver which helps in managing further liver cell damage. It also increases the levels of certain chemical messengers (such as dopamine, noradrenaline, adrenaline, serotonin, melatonin) in the brain that can stabilize mood and mental health. It can also reduce the production of certain chemicals in the body that causes pain and inflammation. DIRECTIONS FOR USETake ENSAME 400 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. It is preferably taken before meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF ENSAME 400 TABLETCOMMON Nausea Stomach pain Diarrhea Bloating Stomach discomfort RAREStop taking ENSAME 400 TABLET and consult your doctor immediately if you experience any of the following side effects: signs of serotonin syndrome (such as feeling agitated, hallucinations, confusion, loss of consciousness, fast heartbeat, feeling dizzy, increased sweating, flushing, tremors, stiff muscles or muscle twitching, loss of coordination, nausea, vomiting, diarrhea or seizures) signs of allergic reactions (such as skin rash, swelling of the hands, face, tongue, neck or throat, increased fluid in tissues, fast heart rate, difficulty in breathing) worsening of depression
Warnings & Precautions
& PRECAUTIONSPREGNANCYENSAME 400 TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. BREASTFEEDINGENSAME 400 TABLET is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines if you experience dizziness after taking ENSAME 400 TABLET as a precaution. KIDNEYENSAME 400 TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it. ALLERGYDo not take ENSAME 400 TABLET if you are allergic to S-Adenosyl-L-Methionine. OTHERSENSAME 400 TABLET is not recommended for use if you: have bipolar disease (alternative episodes of happiness and sadness) Before taking ENSAME 400 TABLET, inform your doctor if you: have anemia (low RBC in blood) have vitamin B12 or folic acid deficiency have a previous history of suicidal thoughts Use in pediatrics: The safety and effectiveness of ENSAME 400 TABLET have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it. Use in geriatrics: ENSAME 400 TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug-Drug interactions: Before taking ENSAME 400 TABLET, inform your doctor if you are taking any of the following medicines such as: other medicines used to manage depression (Ex. phenelzine, iproniazid, isocarboxazid, nialamide, tranylcypromine, moclobemide, fluoxetine, paroxetine, clomipramine, amitriptyline, imipramine etc.) levodopa (a medicine used to manage Parkinson’s disease) tryptophan (an amino acid used to induce sleep) Overdosage: If you or anyone else accidentally took more ENSAME 400 TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : S-Adenosyl-L-Methionine Pharmacological Category : Amino acid Derivatives Therapeutic Indication : Liver disease, Depression, Osteoarthritis Dosage Forms : Tablet, Capsule MORE INFORMATION Keep ENSAME 400 TABLET out of sight and reach of children Store ENSAME 400 TABLET below 25°C
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
26 Nov 2022