Endobloc T Kit 1's

s Directions & For Use Side Effects More Information What ENDOBLOC T is used for? ENDOBLOC T is used to treat pulmonary arterial hypertension (PAH) in adults PAH is high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs Talk to Doctor Pregnancy & Breast Feeding Children & Adolescents Driving & Using Machines Talk to your doctor before taking this medicine, if you: are allergic to Ambrisentan, Tadalafil, soya, or any of the other ingredients of this medicine have scarring of the lungs, of unknown cause (idiopathic pulmonary fibrosis) have anaemia (a reduced number of red blood cells) have swelling in the hands, ankles or feet caused by fluid (peripheral oedema) suffer from lung disease where the veins in the lungs are blocked (pulmonary veno-occlusive disease) have heart problems such as angina (chest pain), heart failure, irregular heartbeats or have had a heart attack have low blood pressure or high blood pressure that is not controlled have had a stroke have kidney or liver problems have stomach ulcers have vision problem, including any damage to your optic nerve have ever had hearing problems such as ringing in the ears, dizziness or loss of hearing have a deformed penis shape or Peyronie’s disease have had an erection that lasted more than 4 hours have blood cell problems such as sickle cell anemia, multiple myeloma or leukemia Do not take ENDOBLOC T if you are pregnant or planning to become pregnant Do not breast-feed while you are taking this medicine ENDOBLOC T is not recommended for children and adolescents aged under 18 years as the safety and effectiveness is not established in this age group ENDOBLOC T may cause side effects, such as low blood pressure, dizziness, tiredness, that may affect your ability to drive or use machines Do not drive or use machines if you are feeling unwell Tell your doctor if you are taking, have recently taken or might take any other medicines such as: cyclosporine (a medicine used after transplant or to treat psoriasis) rifampicin (an antibiotic used to treat tuberculosis) other medicines used to treat pulmonary hypertension such as iloprost, epoprostenol, sildenafil nitrates or guanylate cyclase stimulators medicines used to treat hypertension protease inhibitors, used to treat HIV infection, such as ritonavir ketoconazole, itraconazole (medicines used to treat fungal infection) phenobarbital, phenytoin, carbamazepine used to treat fits other medicines for erectile dysfunction (impotence) Always take this medicine exactly as your doctor has told you to Swallow the medicine with a glass of water Do not split, crush or chew the medicine If you take more ENDOBLOC T If you take more ENDOBLOC T, you may be more likely to have side effects, such as headache, flushing, dizziness, nausea (feeling sick), or low blood pressure that could cause light-headedness Contact your doctor or go to nearest hospital immediately If you forget to take ENDOBLOC T If you forget a dose of ENDOBLOC T, just take the medicine as soon as you remember, then carry on as before Do not take two doses at the same time to make up for a forgotten dose If you stop taking ENDOBLOC T Do not stop taking ENDOBLOC T without your doctor's advice Serious Common Uncommon Rare Very Rare Like all medicines, this medicine can cause side effects, although not everybody gets them. allergic reactions marked by rash or itching and swelling (usually of the face, lips, tongue or throat) which may cause difficulty in breathing or swallowing swelling (oedema), especially of the ankles and feet heart failure (this is due to the heart not pumping out enough blood, causing shortness of breath, extreme tiredness and swelling in the ankles and legs) decreased eyesight in one or both eyes sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness erection that lasts more than 4 hours (with or without pain) anaemia (reduced number of red blood cells) marked by tiredness, weakness, shortness of breath and generally feeling unwell hypotension (low blood pressure) flushing (redness of the skin) vomiting rash chest pain/discomfort blurry or other changes to vision fainting running nose constipation ringing in the ears (tinnitus) liver injury sudden hearing loss NA NA Additional Information Storage NA Store at room temperature (15-25ºC) Keep this medicine out of the reach of children Do not use this medicine after the expiry date