Duvanta NP 20mg Tablet 10'S

Neuropathic Pain (649)Rx required

Key Information

Generic Name

Generic Name Duloxetine 20 mg+Methylcobalamin 500 mcg

Manufacturer

Intas Pharmaceuticals Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

DUVANTA NP 20MG TABLET is a combination of Duloxetine and Methylcobalamin which belongs to the group of medicines called Serotonin and Norepinephrine Reuptake Inhibitors (SNRI) and Vitamins. It is indicated for the management of neuropathic pain. DUVANTA NP 20MG TABLET is not recommended for use in patients with liver or severe kidney disease. Contact your doctor before taking DUVANTA NP 20MG TABLET should be used with caution in patients with kidney disease. [GBNKKEYWORD] is generally not recommended for use in pregnancy unless necessary. DUVANTA NP 20MG TABLET should not be used by breastfeeding women because it may pass through the breast milk.DUVANTA NP 20MG TABLET is generally not advised for use in children and adolescents under the age of 18 unless necessary. DUVANTA NP 20MG TABLET should be used with caution in patients over the age of 65. Specific serious

Uses

OF DUVANTA NP 20MG TABLET Manage neuropathic pain

How It Works

DUVANTA NP 20MG TABLET helps manage neuropathic pain, whereas duloxetine increases serotonin and noradrenaline levels in the brain. These messengers inhibit the pain signals reaching the brain and methylcobalamin, which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells, Together, relieves neuropathic pain.

Directions for Use

Take this medicine as advised by your physician. Swallow this medicine as a whole with a glass of water and do not crush or chew the medicine.

Side Effects

suicidal ideation or behaviour (suicidality) after taking DUVANTA NP 20MG TABLET. This medicine's most common side effects are headache, feeling sleepy, nausea, dry mouth, etc. Contact your physician if any of the symptoms worsen. USES OF DUVANTA NP 20MG TABLET Manage neuropathic pain HOW DUVANTA NP 20MG TABLET WORKSDUVANTA NP 20MG TABLET helps manage neuropathic pain, whereas duloxetine increases serotonin and noradrenaline levels in the brain. These messengers inhibit the pain signals reaching the brain and methylcobalamin, which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells, Together, relieves neuropathic pain. DIRECTIONS FOR USETake this medicine as advised by your physician. Swallow this medicine as a whole with a glass of water and do not crush or chew the medicine. SIDE EFFECTS OF DUVANTA NP 20MG TABLETCOMMON headache, feeling sleepy nausea, dry mouth constipation, diarrhoea, stomach pain, vomiting, heartburn or indigestion, flatulence lack of appetite trouble sleeping, feeling agitated decreased sexual drive failure to experience orgasm anxiety unusual dreams dizziness, sluggish, tremor, numbness, pricking or tingling of the skin blurring of eyes tinnitus feeling pressure on the heart increased blood pressure, flushing increased yawning increased sweating, (itchy) rash muscle pain or spasm painful urination, frequent urination problems getting an erection changes in ejaculation falls fatigue weight loss UNCOMMON throat inflammation causing a hoarse voice suicidal thoughts, difficulty sleeping, grinding or clenching the teeth, feeling disorientated, lack of motivation sudden involuntary jerks or muscle twitches, the sensation of restlessness or an inability to sit or stand still, feeling nervous, difficulty in concentration, changes in sense of taste, difficulty in controlling movement ex. lack of coordination or involuntary muscle movements, restless legs syndrome and decreased sleep large pupils, problems with eyesight dizziness or spinning sensation (vertigo), ear pain heart palpitations fainting, dizziness, light-headedness or fainting on standing up, cold fingers and toes throat tightness, nose bleeds vomiting blood or black tarry stools (faeces), gastroenteritis, burping, difficulty in swallowing night sweats, hives, cold sweats, sensitivity to sunlight and bruises easily muscle tightness or twitching difficulty in urination abnormal vaginal bleeding abnormal periods such as heavy, painful, irregular or prolonged periods or light or missed periods, pain in the testicles or scrotum pain in the chest coldness, thirsty shivers, feeling hot abnormal gait weight gain increases in liver enzymes increase in potassium increase in creatine phosphokinase elevated sugar levels increased cholesterol in the blood RARE decreased thyroid function causing tiredness or weight gain low sodium levels (hyponatremia), dehydration syndrome of inappropriate secretion of antidiuretic hormone (SIADH) serotonin syndrome (feelings of great happiness, drowsiness, clumsiness, restlessness, feeling of being drunk, fever, sweating or rigid muscles) fits increased pressure in the eye (glaucoma) coughing, wheezing and shortness of breath, accompanied by a high fever mouth inflammation passing red-coloured stools bad breath, inflammation of the large intestine causing diarrhoea contraction of the jaw muscle change in urine smell symptoms of menopause abnormal breast milk production in men or women excessive vaginal bleeding after birth (postpartum haemorrhage) acne-like and blister rashes Stop taking DUVANTA NP 20MG TABLET and contact your physician immediately if you experience any of the following side effects: allergic reaction such as itchy rash, swelling of the face, lips, tongue or throat causing difficulty in breathing symptoms of Stevens-Johnson syndrome such as serious illness with blisters on the skin, mouth, eyes and genitals symptoms of liver disease such as yellowish discolouration of the skin or whites of the eyes (jaundice), abdominal pain vomiting blood or black tarry stools mania (over-activity), hallucinations, aggression and anger suicidal behaviour or thoughts about suicide or dying new or worsening depression new or worsening anxiety feeling very agitated or restless panic attacks insomnia new or worse irritability aggressiveness, being angry or violent acting on dangerous impulses other unusual changes in behaviour or mood

Warnings & Precautions

& PRECAUTIONSPREGNANCY[GBNKKEYWORD] is generally not recommended for use in pregnancy unless considered necessary. Contact your doctor before taking it. BREASTFEEDINGDUVANTA NP 20MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy or sleepy after taking DUVANTA NP 20MG TABLET. ALCOHOLAvoid consumption of alcohol while taking DUVANTA NP 20MG TABLET as it may lead to unwanted effects. KIDNEYDUVANTA NP 20MG TABLET is not recommended for use in patients with severe kidney disease. Contact your doctor before taking it. LIVERDUVANTA NP 20MG TABLET is not recommended for use in patients with liver disease. Contact your doctor before taking it. ALLERGYDo not take DUVANTA NP 20MG TABLET if you are allergic to Duloxetine, Methylcobalamin or sucrose, lactose, some sugars or other ingredients of this medicine. HEART DISEASEDUVANTA NP 20MG TABLET should be used with caution in patients with heart diseases. Contact your doctor before taking it. OTHERSDUVANTA NP 20MG TABLET is not recommended for use if you have: uncontrolled blood pressure Before taking DUVANTA NP 20MG TABLET, inform your doctor if you have: seizures mania major depressive disorder bipolar disorder depression or anxiety glaucoma Leber’s disease history of bleeding disorders low sodium levels low potassium levels urinary incontinence or retention orthostatic hypotension and syncope concomitant illness decreased gastric emptying diabetes pernicious anaemia iron or folic acid deficiency Use in Paediatrics: DUVANTA NP 20MG TABLET is generally not recommended for use in children and adolescents under 18 years of age unless necessary. Contact your doctor before taking it. Use in Geriatrics: DUVANTA NP 20MG TABLET should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking it.

Drug Interactions

SA. Drug-Drug interactions: Inform your physician if you are using: medicines used for depression like moclobemide, fluvoxamine, nortriptyline, amitriptyline, imipramine, desipramine, clomipramine, paroxetine, fluoxetine, venlafaxine benzodiazepines (medicines used for seizures, insomnia) Ex. diazepam tramadol, pethidine (medicines used for severe pain) antipsychotics like olanzapine and risperidone (medicines used to manage psychoses) phenobarbital (medicines used to manage seizures) antihistamines like chlorpheniramine (used for allergies) linezolid (medicines used to manage bacterial infections) St John's Wort (medicines used for depression) sumatriptan (medicines used for migraine) tryptophan (nutrient supplement) theophylline (medicines used to manage asthma) tolterodine (a medicine used for overactive bladder) flecainide, propafenone and metoprolol (medicines used to manage heart diseases) oral contraceptives (used for managing pregnancy) steroids (medicines used to manage pain and inflammation) Ex. prednisone anticoagulants Ex. warfarin (medicines used to manage blood clots) antiplatelet agents like dipyridamole (medicines used to manage blood cell clumping) aluminium- and magnesium-containing antacids (medicines used to manage heartburn or indigestion) cimetidine, famotidine (medicines used for stomach ulcers) ciprofloxacin or enoxacin (medicines used for bacterial infections) diuretics (medicines used to manage high blood pressure) Ex. Chlorothiazide neomycin, chloramphenicol (medicines used to manage bacterial infections) colchicine (medicines used to manage gout) metformin (medicines used to manage diabetes mellitus) omeprazole, lansoprazole (medicines used to manage stomach ulcers, indigestion) cholestyramine (medicines used to decrease high cholesterol levels) potassium chloride (medicines used to manage potassium correction) methyldopa (medicines used for hypertension) antimetabolites like fluorouracil (medicines used to manage cancer) Overdosage: If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are somnolence, coma, serotonin syndrome (feelings of great happiness, drowsiness, clumsiness, restlessness, feeling of being drunk, fever, sweating or rigid muscles), seizures, syncope, tachycardia, hypotension, hypertension and vomiting. SYNOPSIS Drug : Duloxetine, Methylcobalamin Pharmacological Category : Serotonin and Norepinephrine Reuptake Inhibitor and Vitamins Therapeutic Indication : Neuropathic pain Dosage Forms : Tablet MORE INFORMATION Keep out of reach from children Store DUVANTA NP 20MG TABLET below 30°C

Frequently Asked Questions

Common questions and answers about Duvanta NP 20mg Tablet 10'S.

Q

How does DUVANTA NP 20MG TABLET function?

A

DUVANTA NP 20MG TABLET helps manage neuropathic pain, where duloxetine works by increasing the levels of serotonin and noradrenaline in the brain. These messengers inhibit the pain signals reaching the brain and methylcobalamin, which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells, Together, they relieve neuropathic pain.

Q

Does DUVANTA NP 20MG TABLET cause suicidal thoughts?

A

Yes. DUVANTA NP 20MG TABLET causes suicidal thoughts. Stop taking DUVANTA NP 20MG TABLET and contact your doctor if you experience any unusual symptoms, like suicidal ideation or behaviour.

Q

Does DUVANTA NP 20MG TABLET cause weight gain?

A

Yes. DUVANTA NP 20MG TABLET may cause weight gain with long-term use. Contact your doctor before taking it.

Q

Does DUVANTA NP 20MG TABLET cause sleepiness?

A

Yes. DUVANTA NP 20MG TABLET may cause sleepiness. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling sleepy. Do not consume alcohol, as it can aggravate your sleepiness. Contact your doctor if the symptom does not improve.

Q

What are the side effects of taking DUVANTA NP 20MG TABLET?

A

The most common side effects of this medicine are headache, feeling sleepy, nausea, dry mouth, etc. Contact your physician if any of the symptoms worsen.

Article Information

I(

Written By

ity (HPRA). [Revised in February 2021] [Accessed on 14th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/7e72e981-379d-4e2b-989b-7e3ff3db9b91.pdf 7.  Eli Lilly and Company Limited. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed on 14th June 2022] https://www.medicines.org.uk/emc/files/pil.3880.pdf 8. Recipharm Limited. Electronic Medicines Compendium (EMC). [Revised in April 2019] [Accessed on 14th June 2022] https://www.medicines.org.uk/emc/files/pil.5716.pdf 9. Duloxetine. Torrent Pharmaceuticals Ltd. [Revised in July 2019] [Accessed on 14th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2895.pdf AUTHOR DETAILS Written By Dr. Dhivakaran R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

24 Dec 2022

Tags

#neuropathic pain (649)#generic name duloxetine 20 mg+methylcobalamin 500 mcg