DURITE PLUS 10 Tablet 10's
Key Information
Generic Name
Generic Name Spironolactone 50 mg+Torsemide 10 mg
Manufacturer
Leeford Healthcare Ltd (Generics)
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
DURITE PLUS 10 TABLET is a fixed-dose combination of Spironolactone and Torsemide which belongs to the group of medicines called Diuretics. It is used to reduce fluid accumulation (oedema) in the body that is caused due to severe liver, kidney or heart problems. It can also be used to manage hyperaldosteronism (excessive secretion of aldosterone in the body) and resistant hypertension (high blood pressure that is not controlled by other medicines). Before taking DURITE PLUS 10 TABLET inform your doctor if you have any liver, kidney or heart problems. Avoid consumption of alcohol while taking DURITE PLUS 10 TABLET as it may make you feel dizzy or faint even while changing posture. Avoid consuming potassium rich diet or potassium supplements while taking DURITE PLUS 10 TABLET, as it may further increase the levels of potassium in your body. DURITE PLUS 10 TABLET is not recommended for use in pregnant or breastfeeding women due to increased risk of
Uses
OF DURITE PLUS 10 TABLETIt is used to manage: oedema caused due to severe liver, kidney or heart problems hyperaldosteronism (excessive secretion of aldosterone in the body) resistant hypertension (high blood pressure that is not controlled by other medicines)
How It Works
DURITE PLUS 10 TABLET contains two medicines namely spironolactone and torsemide. Both spironolactone and torsemide acts by removing the excess water and electrolytes (sodium and chloride) from the body in the form of urine which helps in reducing blood pressure. Additionally, spironolactone can manage the loss of potassium via urine and can block the release of certain chemicals in the kidneys (aldosterone) that causes endocrine problems.
Directions for Use
Take DURITE PLUS 10 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking DURITE PLUS 10 TABLET unless your doctor tells you to stop.
Side Effects
electrolytes in your body and may make you feel dizzy or tired very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and may increase or decrease the dose of this medicine accordingly. The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, increased urination and impotence. Consult your doctor if any of the side effect bothers you. USES OF DURITE PLUS 10 TABLETIt is used to manage: oedema caused due to severe liver, kidney or heart problems hyperaldosteronism (excessive secretion of aldosterone in the body) resistant hypertension (high blood pressure that is not controlled by other medicines) HOW DURITE PLUS 10 TABLET WORKSDURITE PLUS 10 TABLET contains two medicines namely spironolactone and torsemide. Both spironolactone and torsemide acts by removing the excess water and electrolytes (sodium and chloride) from the body in the form of urine which helps in reducing blood pressure. Additionally, spironolactone can manage the loss of potassium via urine and can block the release of certain chemicals in the kidneys (aldosterone) that causes endocrine problems. DIRECTIONS FOR USETake DURITE PLUS 10 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking DURITE PLUS 10 TABLET unless your doctor tells you to stop. SIDE EFFECTS OF DURITE PLUS 10 TABLETCOMMON headache, dizziness nausea, vomiting general weakness increased urination excessive thirst impotence indigestion RAREStop taking DURITE PLUS 10 TABLET and contact your doctor immediately if you experience any of the following side effects: irregular heartbeat, chest pain bleeding from the gut or diarrhoea hyperglycaemia (increased blood glucose levels causing excessive urination and thirst, fatigue, headache) hyperuricemia (increased uric acid levels in blood causing joint pain, redness, swelling and of joints) hypokalaemia (low blood potassium levels causing constipation, tiredness, muscle weakness, tingling and numbness) hypotension (low blood pressure causing fainting, tiredness, blurred vision, nausea) hypovolemia (loss of body fluids causing headache, dizziness, low blood pressure, weakness, drowsiness, confusion, loss of appetite and cramps) blood clot formation in the body skin rash rectal bleeding feeling faint
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedDURITE PLUS 10 TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it. BREASTFEEDINGContraindicatedDURITE PLUS 10 TABLET is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESUse with CautionDo not drive or handle any heavy tools or machines if you experience dizziness, drowsiness, or blurred vision after taking DURITE PLUS 10 TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking DURITE PLUS 10 TABLET as it might make you feel dizzy or faint even when you change posture. KIDNEYContraindicatedDURITE PLUS 10 TABLET is not recommended for use in patients with moderate to severe kidney diseases (such as difficulty in passing urine or acute renal failure). Therefore, consult your doctor before taking it. LIVERConsult your doctorDURITE PLUS 10 TABLET is not recommended for use in patients liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it. ALLERGYContraindicatedDo not take DURITE PLUS 10 TABLET if you are allergic to Torsemide, Spironolactone or sulfonylureas (Ex. glimepiride, glipizide). HEART DISEASEContraindicatedDURITE PLUS 10 TABLET is not recommended for use in patients with heart diseases (such as low blood pressure or abnormal heart rate). Therefore, consult your doctor before taking it. OTHERSDURITE PLUS 10 TABLET is not recommended for use if you: have high levels of potassium in your blood (hyperkalaemia) have Addison’s disease (deficiency of cortisol and aldosterone) Use in paediatrics: There is no proper information regarding the use of DURITE PLUS 10 TABLET in children and adolescents (below 18 years). Therefore, consult your doctor before taking it. Use in geriatrics: DURITE PLUS 10 TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking DURITE PLUS 10 TABLET, inform your doctor if you are taking any of the following medicines such as: cholestyramine (a medicine used to control blood cholesterol levels) medicines that exert effects on heart function during emergency conditions (Ex. adrenaline, noradrenaline) probenecid (a medicine used to manage gout) lithium (a medicine used to manage mental illness) medicines used to reduce anxiety and to induce sleep (Ex. phenobarbital) corticosteroids (used to manage inflammation) Ex. methylprednisolone adrenocorticotropic hormone (used to manage cortisol deficiency) medicines used to relax muscles (Ex. tubocurarine) medicines used for pain relief (Ex. indomethacin, aspirin, morphine, fentanyl, codeine) cardiac glycosides (used to manage cardiac failure) Ex. digoxin carbenoxolone (a medicine used to manage ulcers) medicines used to manage bacterial infections Ex. trimethoprim, sulfamethoxazole, ceftriaxone, cefazolin, gentamycin, streptomycin cotrimoxazole (a medicine used to manage fungal infections) cisplatin (used to manage cancer) other potassium-sparing diuretics (used to manage fluid accumulation) Ex. eplerenone heparin and low molecular weight heparin (used to manage blood clots) potassium supplements (used to manage potassium deficiency) Ex. potassium chloride medicines used to manage high blood pressure such as ACE inhibitors, angiotensin II blockers or beta-blockers (Ex. enalapril, telmisartan, valsartan, propranolol) medicines used to manage diabetes (Ex. metformin, glimepiride) B. Drug-Food interactions Avoid foods rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes such as potassium chloride. Overdosage: If you or anyone else accidentally took more DURITE PLUS 10 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include dehydration, low blood pressure, decreased body fluids and electrolytes levels, low blood sodium levels, abnormal blood potassium levels, increased RBC count, drowsiness, mental confusion, erythematous rash, nausea, vomiting, dizziness, diarrhoea, or liver problems. SYNOPSIS Drug : Spironolactone, torsemide Pharmacological Category : Potassium sparing diuretics, Loop diuretics Therapeutic Indication : Oedema, hypertension, Hyperaldosteronism Dosage Forms : Tablet MORE INFORMATION Keep DURITE PLUS 10 TABLET out of reach of children Store DURITE PLUS 10 TABLET at room temperature
Frequently Asked Questions
Common questions and answers about DURITE PLUS 10 Tablet 10's.
What is the use of DURITE PLUS 10 TABLET?
DURITE PLUS 10 TABLET is used to reduce fluid accumulation (oedema) in the body that is caused due to severe liver, kidney or heart problems. It can also be used to manage hyperaldosteronism (excessive secretion of aldosterone in the body) and resistant hypertension (high blood pressure that is not controlled by other medicines).
Can I take DURITE PLUS 10 TABLET daily?
Take DURITE PLUS 10 TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests you the number of doses that needs to be taken per day.
What are the possible side effects of DURITE PLUS 10 TABLET?
The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, and increased urination. It may also cause impotence in men. Consult your doctor if any of the side effect bothers you. Also inform your doctor immediately if you experience irregular heartbeat, joint pain, muscle pain, extreme dizziness or fainting or rectal bleeding after taking DURITE PLUS 10 TABLET.
What is the best time to take DURITE PLUS 10 TABLET?
It is advisable to take DURITE PLUS 10 TABLET in the morning preferably after meals. This may avoid frequent urination at the night. However, consult your doctor regarding the time of administration of DURITE PLUS 10 TABLET.
How long does it take for DURITE PLUS 10 TABLET to show the results?
It may take a few weeks for DURITE PLUS 10 TABLET to show the results, and so take DURITE PLUS 10 TABLET regularly as advised by your physician to see the optimum results.
Can DURITE PLUS 10 TABLET cause dizziness?
Yes, DURITE PLUS 10 TABLET may cause dizziness due to the loss of fluids from the body. To avoid this, keep yourself hydrated by drinking plenty of fluids. Avoid driving or operating any tools or machines if you feel dizzy. Consult your doctor if you experience extreme dizziness.
Can I consume alcohol while taking DURITE PLUS 10 TABLET?
Avoid consumption of alcohol while taking DURITE PLUS 10 TABLET as it might make you feel dizzy or faint even when you change posture.
Do I have any food restrictions while taking DURITE PLUS 10 TABLET?
Avoid food rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes containing potassium while taking DURITE PLUS 10 TABLET. It is because DURITE PLUS 10 TABLET can reabsorb potassium in the kidneys, and so additionally consumption of potassium rich foods or supplements may further increase the levels of potassium in the blood.
Do we need any laboratory investigations while taking DURITE PLUS 10 TABLET?
Yes. DURITE PLUS 10 TABLET may alter the electrolyte balance in your body, and make you feel tired or dehydrated very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and increase or decrease the dose of this medicine accordingly.
Can DURITE PLUS 10 TABLET reduce my weight?
DURITE PLUS 10 TABLET does not have any impact on reducing your weight. But, due to removal of excess water from the body, you may experience a slight reduction in body weight.
Can I take DURITE PLUS 10 TABLET to reduce my postpartum belly?
No. DURITE PLUS 10 TABLET is not indicated for use in postpartum women. Do not take DURITE PLUS 10 TABLET unless your doctor has prescribed it. It is not advisable to breastfeed while taking DURITE PLUS 10 TABLET. Consult your doctor before taking DURITE PLUS 10 TABLET.
Can DURITE PLUS 10 TABLET cause cancer?
No. Research does not suggest any risk of cancer while taking [GBNEYWORD]. If you are doubtful consult your doctor for advice.
Can I take DURITE PLUS 10 TABLET on my own?
No. DURITE PLUS 10 TABLET is a prescription medicine. It should be used only when prescribed by a physician. Do not take DURITE PLUS 10 TABLET on your own without consulting your doctor.
Can DURITE PLUS 10 TABLET affect sense of hearing?
Yes, some rare cases of hearing loss have been reported with the use of DURITE PLUS 10 TABLET. This condition is often reversible after discontinuing the therapy. However, consult your doctor immediately if you experience any disturbances in the sense of hearing.
Can the use of DURITE PLUS 10 TABLET cause frequent urination?
Yes. DURITE PLUS 10 TABLET may cause frequent urination. It tends to excrete the accumulated fluid from the body in the form of urine. As a result, you may experience an increase in tendency to urinate. If this bothers you, contact your doctor.
Can the use of [GNKEYWORD] make me more tired?
Yes. DURITE PLUS 10 TABLET may make you feel tired easily because it removes the excess fluids from the body. This reduces your energy levels and make you feel very tired. To avoid this, keep yourself hydrated by drinking plenty of fluids. If you experience extreme tiredness that hinders your daily activities, consult your doctor for advice.
Article Information
Written By
DETAILSWritten By Srilekha. R, B.Pharm
Medical Content Writer
Last Updated
04 Feb 2023