Durataz 4.5gm Injection 1's

Bacterial Infections (2507)Rx required

Key Information

Generic Name

Generic Name Piperacillin 4 gm+Tazobactam 500 mg

Manufacturer

Aristo Pharmaceuticals Pvt Ltd

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT DURATAZ 4.5GM INJECTIONDURATAZ 4.5GM INJECTION is a combination of Piperacillin and Tazobactam which belongs to the group of medicines called Antibiotics. It is used to manage several bacterial infections such as lower respiratory tract infections such as pneumonia, acute bacterial exacerbation causing breathing difficulties, urinary tract infections, pyelonephritis, skin infections, abdominal, biliary tract infections and female pelvic infections such as postpartum endometritis or pelvic inflammatory disease, bacteraemia, and bacterial meningitis in infants and children. It is also used along with other antibacterial agents in the management of neutropenic caused by bacterial infection. Pneumonia is an infection which ca

Uses

inflammation in the air sac producing cough with phlegm and shortness of breath. Pyelonephritis is a urinary tract infection affecting the urinary bladder later gets spreads to the kidneys. Bacteraemia is an infectious condition indicating presence of bacteria in the blood stream. Bacterial meningitis is an infection caused by bacteria in the region surrounding the brain. Neutropenic is low levels of neutrophils (a type of white blood cells) in our body. Kindly inform your doctor or your health-care professional before any laboratory tests as DURATAZ 4.5GM INJECTION will interact with medical investigations. Inform your doctor if you are allergic to any antibiotics or other medicines. DURATAZ 4.5GM INJECTION should not be used in patients allergic to penicillin antibiotics, cephalosporin, and other beta-lactam antibiotics. DURATAZ 4.5GM INJECTION should be used with caution in patients with pre-existing diarrhoea, low potassium levels, kidney, and liver diseases. Avoid concomitant use of other aminoglyco

How It Works

DURATAZ 4.5GM INJECTION works by destroying the bacterial growth responsible for causing infections. Piperacillin works by interrupting the cell wall formation by binding with the enzymes responsible for cell wall synthesis. This binding causes defects in the cell wall leading to cell death causing death of the organism. Tazobactam is responsible for the irreversible termination of enzymes (beta- lactamases) that protect the organism from antibiotics and produces less anti-bacterial actions when given alone so it’s always used in combination with other antibiotics. Thus, both the substances works by managing cell growth and function inhibiting bacterial growth.

Directions for Use

DURATAZ 4.5GM INJECTION will be administered into the vein (intravenously) by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects

DURATAZ 4.5GM INJECTION are diarrhoea, yeast infection, headache, sleeplessness, stomach pain, vomiting, nausea, constipation, skin rash, itching, fever, and injection site reaction. USES OF DURATAZ 4.5GM INJECTIONIt is used to manage the following infections: intra-abdominal infection such as appendicitis and peritonitis skin and skin structure infection such as cutaneous abscesses, cellulitis, diabetic foot female pelvic infections such as postpartum endometritis or pelvic inflammatory disease lower respiratory tract infection such as community-acquired pneumonia, and ventilator-associated pneumonia bacterial septicaemia HOW DURATAZ 4.5GM INJECTION WORKSDURATAZ 4.5GM INJECTION works by destroying the bacterial growth responsible for causing infections. Piperacillin works by interrupting the cell wall formation by binding with the enzymes responsible for cell wall synthesis. This binding causes defects in the cell wall leading to cell death causing death of the organism. Tazobactam is responsible for the irreversible termination of enzymes (beta- lactamases) that protect the organism from antibiotics and produces less anti-bacterial actions when given alone so it’s always used in combination with other antibiotics. Thus, both the substances works by managing cell growth and function inhibiting bacterial growth. DIRECTIONS FOR USEDURATAZ 4.5GM INJECTION will be administered into the vein (intravenously) by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF DURATAZ 4.5GM INJECTIONCOMMON diarrhoea yeast infection headache sleeplessness stomach pain, vomiting, nausea, constipation skin rash, itching fever, injection site reaction UNCOMMON low blood pressure inflammation of the veins skin redness, skin lesions joint and muscle pain chills hypokalaemia, breathing difficulty abnormal lab investigations RARE lack of white blood cells (agranulocytosis), bleeding nose serious infection of colon inflammation of inner lining of mouth peeling of skin Contact your immediately if you experience any of the following side effects after receiving DURATAZ 4.5GM INJECTION serious skin rashes appear as reddish target-like spots or circular patches often with blisters,) ulcers in mouth, throat, nose, extremities, genitals red and swollen eyes (Stevens-Johnson syndrome, dermatitis bullous, dermatitis exfoliative, toxic epidermal necrolysis) a potentially fatal allergic condition (drug reaction with eosinophilia and systemic symptoms) involving skin and other organs such as the kidney and liver skin condition (acute generalised exanthemata’s pustulosis) symptoms include numerous tiny fluids filled blisters with swollen and reddened skin swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or trouble breathing (angioedema) yellowing of the eyes or skin (jaundice) convulsions decrease in blood cells severe diarrhoea with fever

Warnings & Precautions

& PRECAUTIONSPREGNANCYUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in pregnant women. Consult your doctor before receiving the medicine. BREASTFEEDINGUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in breast-feeding women. Consult your doctor before receiving the medicine. DRIVING AND USING MACHINESUse with CautionDo not drive or handle heavy machines if you experience dizziness, drowsiness, tired, or if you have blurred vision while receiving DURATAZ 4.5GM INJECTION. ALCOHOLContraindicatedConsumption of alcohol is not recommended during management with DURATAZ 4.5GM INJECTION. KIDNEYUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in patients with kidney diseases and patients on haemodialysis. Consult your doctor before receiving the medicine. LIVERUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in patients with liver diseases and patients with abnormal liver tests. Consult your doctor before receiving the medicine. ALLERGYContraindicatedDo not receive DURATAZ 4.5GM INJECTION if you are allergic to Piperacillin or Tazobactam or to any other ingredients of this medicine. LUNGSUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in patients with community-acquired pneumonia and ventilator-associated pneumonia. Consult your doctor before receiving the medicine. USE IN PEDIATRICSUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in children above 2 months of age. Your doctor will administer the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before receiving the medicine. USE IN GERIATRICSUse with CautionDURATAZ 4.5GM INJECTION should be used with caution in elder patients (above 65 years of age). Consult your doctor before receiving the medicine. OTHERSBefore receiving this medicine inform your doctor if you: are suffering from diarrhoea have low levels of potassium

Drug Interactions

SA. Drug-Drug interactions: Before receiving DURATAZ 4.5GM INJECTION, inform your doctor if you are taking any of the following medicine: other antibiotics used to manage bacterial infections (Ex. gentamycin, streptomycin, neomycin, amikacin, vancomycin) medicine used to manage gout (Ex. Probenecid) medicine used as muscle relaxants during surgery (Ex. vecuronium) medicines used to manage blood clots (Ex. heparin, warfarin, aspirin) methotrexate (used to manage cancer, arthritis, or psoriasis) medicines reducing potassium levels (Ex. furosemide) Overdosage: It is unlikely to receive overdose since it will be administered by the doctor or nurse. If you experience any unusual side effects, consult your doctor immediately. Symptoms of overdose may occur such as nausea, vomiting, diarrhoea, neuromuscular disorders and convulsions. SYNOPSIS Drug : Piperacillin, Tazobactam Pharmacological Category : Beta-lactam antibiotics, Beta-lactamase inhibitors Therapeutic Indication : Bacterial infections Dosage Forms : Injection MORE INFORMATION Keep DURATAZ 4.5GM INJECTION out of reach of children Store at room temperature

Frequently Asked Questions

Common questions and answers about Durataz 4.5gm Injection 1's.

Q

Will DURATAZ 4.5GM INJECTION manage different bacterial infections?

A

Yes, DURATAZ 4.5GM INJECTION is used in cases of serious infections of chest, urinary system and blood along with others.

Q

Can DURATAZ 4.5GM INJECTION be used in children?

A

Yes, it is safe to use DURATAZ 4.5GM INJECTION in children above 2 months of age, dose adjustments are necessary while used in children. Your doctor will administer the correct dose for your child depending on your child’s age, body weight and disease condition.

Q

How will DURATAZ 4.5GM INJECTION manage my infection?

A

DURATAZ 4.5GM INJECTION works by destroying the bacterial growth responsible for causing infections. Piperacillin works by interrupting the cell wall formation by binding with the enzymes responsible for cell wall synthesis. This binding causes defects in the cell wall leading to cell death causing death of the organism. Tazobactam is responsible for the irreversible termination of enzymes (beta- lactamases) that protect the organism from antibiotics and produces less anti-bacterial actions when given alone so it’s always used in combination with other antibiotics. Thus, both the substances works by managing cell growth and function inhibiting bacterial growth.

Q

How long will DURATAZ 4.5GM INJECTION take to manage bacterial infections?

A

DURATAZ 4.5GM INJECTION will start working once it is injected in the blood stream. It will work faster compared with oral antibiotics as it is injected directly into the blood stream. However full course of antibiotic should be given to obtain its efficacy. Your doctor will decide the dose adjustments and termination of the medicine depending upon your health condition.

Article Information

DW

Written By

DETAILS Written By Dr. Janet.C

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

28 Feb 2023

Tags

#bacterial infections (2507)#generic name piperacillin 4 gm+tazobactam 500 mg