DOMSTAL NP 250 Tablet 10's
Key Information
Generic Name
Generic Name Domperidone 10 mg+Naproxen 250 mg
Manufacturer
Torrent Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
DOMSTAL NP 250 TABLET is a combination of Domperidone and Naproxen, which belong to the groups of medicines called antiemetics and NSAIDs (non-steroidal anti-inflammatory drugs), respectively. It is used to manage the symptoms of migraine, menstrual migraine, and chronic daily headaches associated with nausea and vomiting. A migraine is a recurring headache that often involves one
Uses
severe pain that is pulsating or throbbing and is accompanied by nausea, weakness, and sensitivity to sound and light. DOMSTAL NP 250 TABLET is not recommended in patients with severe liver, kidney, or heart problems, stomach ulcers, bleeding in the stomach or intestine, intestinal tears, or pituitary gland tumours. DOMSTAL NP 250 TABLET should be taken with caution in patients with lung disease, diabetes, high cholesterol, systemic lupus erythematosus, a blood clotting disorder, a history of gastrointestinal diseases, and a habit of drinking or smoking. DOMSTAL NP 250 TABLET is not recommended for use during pregnancy, while breastfeeding, or in children less than 5 years old. It should be used with caution in elderly patients (those over the age of 60). The common
How It Works
DOMSTAL NP 250 TABLET effectively manages migraine, which is commonly associated with nausea and vomiting, by blocking the centres in the brain and stomach that regulate nausea and vomiting. It also increases the contractions and movements in the stomach. DOMSTAL NP 250 TABLET stops the pain pathways and reduces the release of substances (prostaglandins) that cause inflammation, thus decreasing pain and inflammation.
Directions for Use
Take DOMSTAL NP 250 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of DOMSTAL NP 250 TABLET for you depending on your age, body weight and disease condition.
Side Effects
DOMSTAL NP 250 TABLETCOMMON dry mouth UNCOMMON decreased sexual drive in men feeling anxious, drowsy and weak headache diarrhoea itchy skin pain or tenderness in breasts RAREStop taking DOMSTAL NP 250 TABLET and talk to your doctor if you experience any of the following side effects: swelling of the hands, feet, ankles, face, lips or throat which may lead to difficulty in swallowing or breathing an itchy, lumpy rash (hives) or nettle rash (urticaria) any uncontrolled movements which include unusual movements of the tongue, irregular eye movements, and abnormal posture such as a twisted neck, muscle stiffness, and trembling very fast or unusual heartbeat a fit or seizure
Warnings & Precautions
& PRECAUTIONSPREGNANCYDOMSTAL NP 250 TABLET is not recommended for use in pregnant women during the first 6 months of pregnancy. DOMSTAL NP 250 TABLET must not be used during the last 3 months of pregnancy. Consult your doctor before taking it. BREASTFEEDINGDOMSTAL NP 250 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel drowsy, dizzy, tired or have blurred vision after taking DOMSTAL NP 250 TABLET. KIDNEYDOMSTAL NP 250 TABLET is not recommended in patients with severe kidney disease. Consult your doctor before taking DOMSTAL NP 250 TABLET. LIVERDOMSTAL NP 250 TABLET is not recommended in patients with severe liver disease. Consult your doctor before taking it. ALLERGYDo not take DOMSTAL NP 250 TABLET if you are allergic to Domperidone or Naproxen. LUNGSDOMSTAL NP 250 TABLET should be used with caution in patients with lung diseases such as asthma, other breathing problems or nasal polyps. Consult your doctor before taking it. HEART DISEASEDOMSTAL NP 250 TABLET not recommended in patients with severe heart disease such as heart failure, prolonged QT corrected interval. It should be used with caution in patients having a stroke or high blood pressure. Consult your doctor before taking DOMSTAL NP 250 TABLET. OTHERSDOMSTAL NP 250 TABLET is not recommended for use if you: have stomach or duodenal ulcers have bleeding in the stomach or intestines have a blockage or tear in the intestine have a tumour of the pituitary gland Before taking DOMSTAL NP 250 TABLET tell your doctor if you: have a history of disorders of the stomach or bowel (ulcerative colitis, Crohn’s disease) have diabetes have a habit of smoking have systemic lupus erythematosus or other connective tissue disorder have a blood clotting disorder Use in paediatrics: DOMSTAL NP 250 TABLET is not recommended for use in children under 5 years of age. Consult your doctor before taking DOMSTAL NP 250 TABLET. Use in geriatrics: DOMSTAL NP 250 TABLET should be used with caution in elderly patients (above 60 years of age). Consult your doctor for advice.
Drug Interactions
SA. Drug–Drug Interactions: Inform your physician if you are taking any of the following drugs before taking DOMSTAL NP 250 TABLET: medicines used to manage heart problems, high blood pressure (Ex. amiodarone, dronedarone, quinidine, disopyramide, captopril, ramipril, losartan, candesartan, dofetilide, sotalol, diltiazem, verapamil) medicines used in the management of psychoses (Ex. haloperidol, pimozide, sertindole), depression (Ex. citalopram, escitalopram), mental illness (Ex. lithium), epilepsy (Ex. phenytoin) medicines used to manage gastrointestinal disorders (Ex. cisapride, dolasetron, prucalopride), antacids (Ex. aluminium hydroxide gel) medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, ciprofloxacin, telithromycin, moxifloxacin, pentamidine) medicines used in the management of cancer (Ex. toremifene, methotrexate, vandetanib, vincamine) Overdosage: If you or anyone else accidentally takes too much DOMSTAL NP 250 TABLET, consult your doctor immediately or visit the nearby hospital. Overdoes of DOMSTAL NP 250 TABLET can cause headaches, nausea, vomiting, sleepiness, confusion, heartburn, fainting, diarrhoea, disorientation, stomach or intestine bleeding, unconsciousness, drowsiness, dizziness, ringing or buzzing sensation in the ears, fits and excitation, unusual eye movements, unusual tongue movements, or abnormal posture (such as a twisted neck). SYNOPSIS Drug : Domperidone, Naproxen Pharmacological Category : NSAIDs, Antiemetics Therapeutic Indication : Migraine, Menstrual migraine and Chronic daily headache Dosage Forms : Tablet MORE INFORMATION Keep DOMSTAL NP 250 TABLET out of reach from children Store below 25°C
Article Information
Written By
DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
26 Nov 2022