Domi UP Spray 15ml
Key Information
Generic Name
Generic Name Ondansetron 2 mg
Manufacturer
Lincoln Pharmaceuticals Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTIONDOMI UP contains Ondansetron which belongs to a group of medicines called anti-emetics, which help to stop feeling or being sick. It is indicated to prevent and manage nausea and vomiting induced by cytotoxic therapy and radiotherapy and post-operative nausea and vomiting. This medicine works by blocking the action of serotonin levels in the brain which ca
Uses
nausea and vomiting during chemotherapy or any other surgery. Cytotoxic chemotherapy triggers the release of serotonin from the enterochromaffin cells of the small intestine. The released serotonins stimulate the vagal afferents through the 5-HT3 receptors and initiate the vomiting reflex. Ondansetron is a selective 5-HT3 receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer management (chemotherapy) or after surgery. Always take DOMI UP exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. Your doctor will decide the right dose depends on your child’s age and body weight. The common
How It Works
DOMI UP is a selective 5-HT3-receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer management (chemotherapy) or after surgery.
Directions for Use
Always take DOMI UP exactly as your doctor has told you. Do not mix medicine with anything (even water) before swallowing it. Shake well before use. It can be taken with or without food.
Side Effects
DOMI UP Cancer chemotherapy-induced nausea and vomiting Postoperative nausea and/or vomiting HOW DOMI UP WORKSDOMI UP is a selective 5-HT3-receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer management (chemotherapy) or after surgery. DIRECTIONS FOR USEAlways take DOMI UP exactly as your doctor has told you. Do not mix medicine with anything (even water) before swallowing it. Shake well before use. It can be taken with or without food. SIDE EFFECTS OF DOMI UPSERIOUS sudden wheezing and chest pain or tightness swelling of the eyelids, lips, mouth, tongue or throat difficulty breathing skin rash fits (seizures) chest pain temporary loss of vision COMMON headache sensation of flushing and warmth constipation RARE dizziness or light headedness blurred vision disturbance in heart rhythm
Warnings & Precautions
& PRECAUTIONSPREGNANCYDOMI UP is not recommended in the first trimester of pregnancy unless necessary. Consult your doctor for advice. BREASTFEEDINGDOMI UP is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor. DRIVING AND USING MACHINESDo not drive or operate any machines while taking this medicine as it may cause dizziness or faintness. LIVERDOMI UP should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice. ALLERGYDo not take if you are allergic (hypersensitive) to Ondansetron. HEART DISEASEDOMI UP should be used with caution in patients suffering from uneven heart beat or any other active heart diseases. Consult your doctor for advice. OTHERSInform your doctor if you have or had, blockage in your gut or suffer from severe constipation surgery to the adenoids or tonsils problems with the levels of salts in blood like potassium and magnesium
Drug Interactions
SInform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following, apomorphine (used to manage Parkinson’s Disease) phenytoin, carbamazepine (used to manage epilepsy) rifampicin, erythromycin (an antibiotic) tramadol (used to manage pain) medicines used to manage heart problems such as abnormal heart beats (anti-arrhythmics) and high blood pressure (betablockers) anthracyclines, trastuzumab (used to manage cancer) ketoconazole (used to manage fungal infection) SYNOPSIS Drug : Ondansetron Pharmacological Category : Selective 5-HT3 Receptor Antagonist Therapeutic Indication : Cancer chemotherapy-induced nausea and vomiting, Postoperative nausea and/or vomiting Dosage Forms : Tablet, Injection, Syrup MORE INFORMATIONStore below 20-25°C and keep out of reach of children.