Dermotrex Gel 30gm
Key Information
Generic Name
Generic Name Methotrexate 1 %
Manufacturer
East West Pharma
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT DERMOTREX GELDERMOTREX GEL contains Methotrexate which belongs to the group of medicines called Antimetabolites. It is used to manage psoriasis. DERMOTREX GEL is also used to manage active rheumatoid arthritis in adults, which is a complex auto-immune disorder resulting in the inflammation of the bones leading to swelling and pain. This medicine may also be used for vitiligo. Psoriasis is a skin condition characterized by itchy scales that is not responsive to conventional managements such as phototherapy and retinoids. Vitiligo is a skin condition characterized by a loss of pigmentation, resulting in the appearance of discoloured patches on the skin. Before using DERMOTREX GEL, it is recommended to inform the doctor about your medical and family history, including the list of medicines (prescription, non-prescription medicines, and herbal medicines) that are being used or taken. DERMOTREX GEL is not recommended to be used by children less than 3 years of age, pregnant women, nursing women, or women planning to get pregnant. Consult your doctor before using the medicine.
Uses
OF DERMOTREX GELIt is used to manage: psoriasis active rheumatoid arthritis in adults (a complex auto-immune disorder resulting in the inflammation of the bones leading to swelling and pain)
How It Works
DERMOTREX GEL contains methotrexate, which belongs to disease-modifying antirheumatic drugs (DMARDs). DERMOTREX GEL decreases the undesired reactions of the body’s own immune-defense mechanism, thereby working as an effective immunosuppressant. It also exhibits anti-inflammatory effects, thereby reducing pain, swelling, and redness. As a result, DERMOTREX GEL manages the symptoms associated with rheumatoid arthritis and psoriasis.
Directions for Use
Always apply DERMOTREX GEL as directed by your physician. It is for external use only. Your doctor will decide your dose and duration of application according to your age and disease condition.
Side Effects
medical pharmacology. Seventh edition. 2013. Page-210, 857. 2. Eskicirak, B., Zemheri, E. and Cerkezoglu, A., 2006. The treatment of psoriasis vulgaris: 1% topical methotrexate gel. International journal of dermatology. [Published in August 2006] [Accessed on 3rd February 2024] https://pubmed.ncbi.nlm.nih.gov/16911386/ 3. Abdelmaksoud, A., Dave, D.D., Lotti, T. and Vestita, M., 2019. Topical methotrexate 1% gel for treatment of vitiligo: A case report and review of the literature. Dermatologic Therapy. [Published on 1st September 2019] [Accessed on 3rd February 2024] https://www.semanticscholar.org/paper/Topical-methotrexate-1-gel-for-treatment-of-A-case-Abdelmaksoud-Dave/0e38f07bfca67bdba9d7cbfe927122d0f136e134 4. DAS, S., Sharadha, M., Venkatesh, M.P., SAHOO, S., TRIPATHY, J. and Gowda, D.V., 2021. Formulation and evaluation of topical nanoemulgel of methotrexate for rheumatoid arthritis. International Journal of Applied Pharmaceutics. [Revised on 22nd June 2021] [Accessed on 3rd February 2024] https://innovareacademics.in/journals/index.php/ijap/article/view/41026/25364 5. Liver Tox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Methotrexate. [Updated on 19th February 2020] [Accessed on 3rd February 2024] https://www.ncbi.nlm.nih.gov/books/NBK548219/#:~:text=Methotrexate%20can%20lead%20to%20serious,regimens%20and%20in%20higher%20doses. 6. Drugs.com Methotrexate Pregnancy and Breastfeeding
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedDERMOTREX GEL is not recommended for use if you are pregnant or are planning to become pregnant since it can be harmful to the fetus (growing baby) and lead to various malformations. Consult your doctor before applying DERMOTREX GEL. BREASTFEEDINGContraindicatedDERMOTREX GEL is not recommended for use if you are a nursing mother. Consult your doctor before applying DERMOTREX GEL. LIVERUse with CautionIt should be used with caution if you are diagnosed with a liver disorder while using DERMOTREX GEL. Consult your doctor before using DERMOTREX GEL. ALLERGYContraindicatedDERMOTREX GEL is not recommended if you are allergic to methotrexate and/or any other ingredients of this DERMOTREX GEL. Consult your doctor before applying DERMOTREX GEL. USE IN PEDIATRICSContraindicatedIt is recommended not to be used by children under the age of 3 years. Consult your doctor before giving DERMOTREX GEL to your child.
Drug Interactions
SA. Drug-Drug Interactions: Inform your doctor if you are using or taking any prescription, non-prescription medicines, ayurvedic, or herbal supplements. Overdosage: If you use too much of this medicine, consult your doctor immediately and visit any nearby hospital. SYNOPSIS Drug : Methotrexate Pharmacological Category : Anti-metabolites Therapeutic Indication : Rheumatoid Arthritis, Psoriasis Dosage Forms : Injection, Gel, Capsule, Tablet MORE INFORMATION Keep DERMOTREX GEL out of the reach and sight of children Store DERMOTREX GEL at room temperature
Frequently Asked Questions
Common questions and answers about Dermotrex Gel 30gm.
What is DERMOTREX GEL used for?
DERMOTREX GEL is used to manage psoriasis. It is a skin condition characterized by itchy scales that is not responsive to conventional managements such as phototherapy and retinoids. It is also used to manage active rheumatoid arthritis in adults, which is a complex auto-immune disorder resulting in the inflammation of the bones, leading to swelling and pain.
Can I use DERMOTREX GEL in pregnancy?
DERMOTREX GEL is not recommended for use in pregnant women and/or in women who are planning pregnancy because it can be harmful for the fetus (growing baby in the womb). Consult your doctor before using it.
Can I use DERMOTREX GEL if I am breastfeeding a baby?
DERMOTREX GEL is not recommended for use during breastfeeding due to a lack of safety data. Consult your doctor before applying it.
Can DERMOTREX GEL be used by children?
DERMOTREX GEL is not recommended for children less than 3 years of age. For children above the age of 3, it is recommended to closely monitor for side effects. It is recommended to consult a doctor before giving DERMOTREX GEL to your child.
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
05 Feb 2024