Daruvir 800mg Tablet 30'S
Key Information
Generic Name
Generic Name Darunavir 800 mg
Manufacturer
Cipla Ltd
Variant
30 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
DARUVIR 800MG TABLET contains Darunavir, which belongs to the group of medicines called Protease Inhibitors. It is used to manage Human Immunodeficiency Virus (HIV) infection. HIV (Human Immunodeficiency Virus) is a virus that impairs the immune system of the human body, and its symptoms may include weight loss, fever or night sweats, fatigue, recurrent infections, etc. DARUVIR 800MG TABLET is not recommended for use in patients allergic to darunavir, cobicistat, ritonavir, and/or sulphonamides and patients suffering from severe liver problems. Before taking DARUVIR 800MG TABLET, inform your doctor if you have diabetes, haemophilia, and/or kidney problems (such as impaired kidney function). DARUVIR 800MG TABLET should be used with caution during pregnancy, only if recommended by your doctor. Women infected with HIV are advised not to breastfeed their children to avoid the spread of infection to the baby.
Uses
OF DARUVIR 800MG TABLET Manage Human Immunodeficiency Virus (HIV) infection
How It Works
DARUVIR 800MG TABLET works by interfering with protease (an enzyme required by HIV-infected cells to make new viruses) which inhibits the production of the new viruses in the body. As a result, it helps to manage the Human Immunodeficiency Virus (HIV) and provides relief from its associated symptoms in affected individuals.
Directions for Use
Take DARUVIR 800MG TABLET as advised by your physician. Do not crush or chew the medicine. Swallow the medicine with a glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects
taking DARUVIR 800MG TABLET are diarrhoea, vomiting, nausea, abdominal pain/distension, indigestion, flatulence, and/or headache. Consult your doctor if any of your symptoms get worse or persist. USES OF DARUVIR 800MG TABLET Manage Human Immunodeficiency Virus (HIV) infection HOW DARUVIR 800MG TABLET WORKSDARUVIR 800MG TABLET works by interfering with protease (an enzyme required by HIV-infected cells to make new viruses) which inhibits the production of the new viruses in the body. As a result, it helps to manage the Human Immunodeficiency Virus (HIV) and provides relief from its associated symptoms in affected individuals. DIRECTIONS FOR USETake DARUVIR 800MG TABLET as advised by your physician. Do not crush or chew the medicine. Swallow the medicine with a glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF DARUVIR 800MG TABLETCOMMON diarrhoea vomiting nausea abdominal pain/distension indigestion flatulence headache tiredness dizziness drowsiness numbness pain or tingling sensation in hands or feet loss of strength difficulty falling asleep UNCOMMON chest pain changes in electrocardiogram rapid heart beating abnormal/decreased skin sensibility pricking sensation attention disturbance loss of memory problems with body balance breathing difficulty cough nosebleed throat irritation mouth/stomach inflammation heartburn retching (urge to vomit) dry mouth abdomen discomfort constipation belching kidney failure kidney stones difficulty in urination excessive/frequent passage of urine urticaria (red itchy welts) severe swelling of the skin and/or other tissues (mostly lips or the eyes) eczema excessive sweating night sweats hair loss acne scaly skin colouration of nails muscle pain muscle cramps/weakness pain in extremities osteoporosis (a condition marked by weak bones) high blood pressure flushing red/dry eyes fever swelling of lower limbs malaise irritability pain symptom of herpes simplex infection such as cold sores around the lips, mouth or tongue, tingling/itching/burning sensation, pain while urination erectile dysfunction enlargement of the breasts sleeping problems sleepiness depression anxiety abnormal dreams decreased sexual drive RARE heart attack slow heartbeat palpitations visual disturbance chills abnormal feelings confusions/disorientation altered mood restlessness fainting seizures/epileptic fits loss or change of taste mouth sores blood vomiting inflammation of dry lips, lips and coated tongue running nose dry skin skin lesions muscle/joints stiffness joint pains with/without inflammation Stop taking DARUVIR 800MG TABLET and contact your doctor immediately if you: have signs of DRESS (Drug reaction with eosinophilia and systemic symptoms) such as severe rash associated with the swelling of the face/lymph glands, fever, tiredness, and/or effects on liver/kidney/lung have signs of severe skin reactions (toxic epidermal necrolysis and Stevens-Johnson syndrome) such as cough, decreased appetite, runny nose, fever, and/or weakness signs of severe liver problems such as yellowing of skin/whites of your eyes, dark (tea-coloured) urine, pale-coloured stools, nausea, vomiting, loss of appetite, pain, aching, and/or sensitivity on your right side below your ribs develop skin rash and itching (when used in combination with raltegravir) develop severe diabetes have signs of pancreatitis (inflammation of the pancreas), which includes stomach pain have symptoms of infection, such as fever and enlarged lymph nodes have signs of autoimmune disorders such as muscle weakness, racing heartbeat, weakness beginning in the hands and feet and moving up towards the trunk of the body, tremors, and/or hyperactivity
Warnings & Precautions
& PRECAUTIONSPREGNANCYDARUVIR 800MG TABLET should be used with caution during pregnancy only if recommended by your doctor. Consult your doctor before taking DARUVIR 800MG TABLET. BREASTFEEDINGDARUVIR 800MG TABLET is not recommended for use by breastfeeding women as it may pass through the breast milk and may result in causing unknown effects on the breastfed baby. However, women infected with HIV are advised not to breastfeed to manage the spread of infection to the baby. Consult your doctor before taking DARUVIR 800MG TABLET. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy after taking DARUVIR 800MG TABLET. ALCOHOLAvoid consumption of alcohol while taking DARUVIR 800MG TABLET since it may increase the risk of developing osteonecrosis (death of bone tissue due to lack of blood supply). KIDNEYDARUVIR 800MG TABLET should be used with caution in patients with impaired kidney function. Consult your doctor before taking the DARUVIR 800MG TABLET. LIVERDARUVIR 800MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with liver problems such as hepatitis B or hepatitis C infection. ALLERGYDo not take DARUVIR 800MG TABLET if you are allergic to darunavir, cobicistat, ritonavir, sulphonamides, and/or any of the other ingredients in this medicine. Consult your doctor before taking DARUVIR 800MG TABLET. OTHERSBefore taking DARUVIR 800MG TABLET, inform your doctor if you have diabetes had a history of opportunistic infection have hemophilia Use in Pediatrics: DARUVIR 800MG TABLET is not recommended for use in children (aged less than 3 years or weighing less than 40 kg). Consult your doctor before taking DARUVIR 800MG TABLET. Use in Geriatrics: DARUVIR 800MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking DARUVIR 800MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking DARUVIR 800MG TABLET, inform your doctor if you are taking any of the following medicines: avanafil (used to manage erectile dysfunction) astemizole, terfenadine (medicines used to manage allergy symptoms) triazolam, midazolam (medicines used to manage insomnia and anxiety) protease inhibitors (medicines used to slow the progression of HIV) Ex. saquinavir, indinavir cisapride (used to manage stomach conditions) colchicine (used to manage gout/familial mediterranean fever) lurasidone, pimozide, quetiapine, sertindole, perphenazine, thioridazine, risperidone (medicines used to manage psychiatric conditions) medicines used to manage migraine headaches such as ergot alkaloids (Ex. dihydroergotamine, ergometrine, methylergonovine) amiodarone, bepridil, ivabradine, quinidine, dronedarone, ranolazine (medicines used to manage certain heart disorders) lovastatin, simvastatin, lomitapide (medicines used to lower cholesterol levels) rifampicin (to manage tuberculosis) lopinavir, ritonavir, efavirenz, saquinavir, cobicistat, raltegravir, maraviroc (medicines used to manage HIV infection) elbasvir, grazoprevir (used to manage hepatitis C infection) alfuzosin (to manage enlarged prostate) sildenafil (to manage high blood pressure in the pulmonary circulation) dabigatran, ticagrelor (to help stop the clumping of platelets in the management of patients with a history of a heart attack) naloxegol (to manage opioid-induced constipation) dapoxetine (to manage premature ejaculation) domperidone (to manage nausea and vomiting) st. john’s wort (herbal medicine used to manage depression) antiviral medicines used to manage AIDS such as non-nucleoside reverse transcriptase inhibitors (Ex. delavirdine, efavirenz), nucleoside reverse transcriptase inhibitors (Ex. lamivudine, emtricitabine), ccr5 antagonists (Ex. maraviroc, vicriviroc), fusion inhibitors (Ex. fuzeon, enfuvirtide) phenytoin, phenobarbital (used to manage seizures) dexamethasone (used to manage inflammation) rifapentine, rifabutin (used to manage tuberculosis) amlodipine, diltiazem, disopyramide, mexiletine, nifedipine, nicardipine, carvedilol, felodipine, flecainide, lidocaine, metoprolol, propafenone, timolol, verapamil (medicines used to manage heart disease) apixaban, rivaroxaban, warfarin, clopidogrel, edoxaban (medicines used to reduce clotting of the blood) medicines used as a hormonal replacement therapy and oestrogen-based hormonal contraceptives (Ex. drospirenone, ethinyl estradiol) pravastatin, rosuvastatin, atorvastatin (medicines used to lower cholesterol levels) clarithromycin (a medicine used to manage bacterial infections) tacrolimus, sirolimus, ciclosporin, everolimus (medicines used to dampen down the immune system) corticosteroids (medicines used to manage inflammation) Ex. betamethasone, fluticasone, mometasone, prednisone, triamcinolone, budesonide buprenorphine, naloxone (medicines used to manage opiate dependence) salmeterol (medicine to manage asthma) lumefantrine, artemether (medicines used to manage malaria) irinotecan, nilotinib, vinblastine, dasatinib, everolimus, vincristine (used to manage cancer) sildenafil, tadalafil, vardenafil (medicines used to manage erectile dysfunction or manage a heart and lung disorder such as pulmonary arterial hypertension) pibrentasvir/glecaprevir (medicines used to manage hepatitis C infection) oxycodone, tramadol, fentanyl (medicines used to manage pain) solifenacin, and fesoterodine (medicines used to manage urologic disorders) alfentanil (a medicine used as a short-acting painkiller during surgical procedures) digoxin (used to manage heart disorders) clarithromycin, rifabutin (medicines used to manage bacterial infections) itraconazole, fluconazole, posaconazole, isavuconazole, clotrimazole (medicines used to manage fungal infections) amitriptyline, paroxetine, desipramine, imipramine, nortriptyline, sertraline, trazodone (medicines used to manage depression and anxiety) methadone (to manage opiate dependence) clonazepam, carbamazepine (medicines used to manage seizures or to manage nerve pain) colchicine (to manage gout or familial Mediterranean fever) bosentan (to manage high blood pressure) estazolam, flurazepam, midazolam, buspirone, clorazepate, diazepam, when used as an injection, zolpidem (sedative agents) metformin (used to manage type 2 diabetes) Over dosage: If you or anyone else accidentally receive too much of DARUVIR 800MG TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Darunavir Pharmacological Category : Protease inhibitor Therapeutic Indication : HIV Infection Dosage Forms : Tablet MORE INFORMATION Keep DARUVIR 800MG TABLET out of reach from children Store the medicine at room temperature
Article Information
Written By
DETAILSWritten By Dr. Dhivakaran R, BDS
Medical Content Writer
Last Updated
30 Sep 2022