DAPARYL VM 500 Tablet 10's
Key Information
Generic Name
Generic Name Dapagliflozin 10 mg+Metformin 500 mg+Vildagliptin 100 mg
Manufacturer
Intas Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
DAPARYL VM 500 TABLET is a combination of Dapagliflozin, metformin, and vildagliptin, which belongs to a group of medicines called Antidiabetic agents. It is used as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus (T2DM). Along with management, follow a regular exercise and diet plan as advised by the doctor to achieve better results. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Metformin works to control blood sugar by helping insulin, naturally produced by your body, decrease the amount of sugar your liver makes and also decrease the amount of sugar your intestines absorb. Vildagliptin is a potent and selective dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycemic control. Vildagliptin inhibition of DPP-4 results in increased fasting and postprandial endogenous levels of the incretin hormones GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide). DAPARYL VM 500 TABLET is not recommended if you have type 1 diabetes, diabetic ketoacidosis, acute or chronic metabolic acidosis, a history of lactic acidosis, or severe dehydration. Before taking it, inform your doctor if you are scheduled for surgery, x-ray or scanning procedures, or vitamin B12 or folic acid deficiency. DAPARYL VM 500 TABLET is not recommended for pregnant and breastfeeding women. The safety and effectiveness of DAPARYL VM 500 TABLET in children and adolescents have not been established. When taking DAPARYL VM 500 TABLET, alcohol consumption is not recommended. The most common
Uses
OF DAPARYL VM 500 TABLET It is used as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus (T2DM).
How It Works
DAPARYL VM 500 TABLET is a combination of dapagliflozin, metformin, and vildagliptin, which helps to lower blood glucose levels. Dapagliflozin works by inhibiting the reabsorption of glucose in the kidneys, causing excess glucose to be excreted through urine. By lowering blood glucose levels, dapagliflozin helps to improve glycemic control in patients with type 2 diabetes. Metformin works to control blood sugar by helping insulin, naturally produced by your body, decrease the amount of sugar your liver makes and also decrease the amount of sugar your intestines absorb. Vildagliptin is a potent and selective dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycemic control. Vildagliptin inhibition of DPP-4 results in increased fasting and postprandial endogenous levels of the incretin hormones GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide).
Directions for Use
Take DAPARYL VM 500 TABLET as advised by your physician. Swallow DAPARYL VM 500 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. Do not stop taking DAPARYL VM 500 TABLET without informing your doctor.
Side Effects
taking DAPARYL VM 500 TABLET are low sugar levels, painful urination, repetitive urination, inflammation of the penis (in men), and allergic reactions. Contact your doctor if any of the above side effects worsen or persist for a longer duration. USES OF DAPARYL VM 500 TABLET It is used as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus (T2DM). HOW DAPARYL VM 500 TABLET WORKSDAPARYL VM 500 TABLET is a combination of dapagliflozin, metformin, and vildagliptin, which helps to lower blood glucose levels. Dapagliflozin works by inhibiting the reabsorption of glucose in the kidneys, causing excess glucose to be excreted through urine. By lowering blood glucose levels, dapagliflozin helps to improve glycemic control in patients with type 2 diabetes. Metformin works to control blood sugar by helping insulin, naturally produced by your body, decrease the amount of sugar your liver makes and also decrease the amount of sugar your intestines absorb. Vildagliptin is a potent and selective dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycemic control. Vildagliptin inhibition of DPP-4 results in increased fasting and postprandial endogenous levels of the incretin hormones GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide). DIRECTIONS FOR USETake DAPARYL VM 500 TABLET as advised by your physician. Swallow DAPARYL VM 500 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. Do not stop taking DAPARYL VM 500 TABLET without informing your doctor. SIDE EFFECTS OF DAPARYL VM 500 TABLETCOMMON Low sugar levels Painful urination Repetitive urination Inflammation of the penis (in men) Allergic reaction Stop taking DAPARYL VM 500 TABLET and consult your doctor immediately if you experience: Fever and/or chills, burning sensation when passing water (urinating), pain in your back or side (urinary tract infection) Swelling of the face, tongue, or throat, difficulties swallowing, hives, and breathing problems (angioedema)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedDAPARYL VM 500 TABLET is not recommended for use by pregnant women. Consult your doctor before taking the medicine. BREASTFEEDINGContraindicatedDAPARYL VM 500 TABLET is not recommended for breastfeeding women as it may pass through breast milk. Consult your doctor before taking DAPARYL VM 500 TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or use any tools or machines if you feel dizzy after taking DAPARYL VM 500 TABLET. ALCOHOLContraindicatedConsumption of alcohol is not recommended while taking DAPARYL VM 500 TABLET. KIDNEYConsult your doctorDAPARYL VM 500 TABLET is not recommended for patients with kidney disease or impairment. It should be used with caution in patients with a history of kidney disease. Consult your doctor before taking DAPARYL VM 500 TABLET. LIVERConsult your doctorDAPARYL VM 500 TABLET is not recommended for patients with severe liver dysfunction. It should be used with caution in patients with liver disease. Consult your doctor before taking DAPARYL VM 500 TABLET. ALLERGYContraindicatedDo not take DAPARYL VM 500 TABLET if you are allergic (hypersensitive) to Dapagliflozin, Metformin, Vildagliptin, or any other ingredients of this medicine. HEART DISEASEConsult your doctorDAPARYL VM 500 TABLET is not recommended for use if you have cardiovascular problems or cardiorespiratory insufficiency. It should be used with caution if you have had a heart attack or stroke. Consult your doctor before taking DAPARYL VM 500 TABLET. USE IN PEDIATRICSConsult your doctorThe safety and effectiveness of DAPARYL VM 500 TABLET in children and adolescents have not been established. Consult your doctor before taking the medicine. USE IN GERIATRICSUse with CautionDAPARYL VM 500 TABLET should be used with caution in elderly patients over 65 years of age. Consult your doctor before taking the medicine. OTHERSDAPARYL VM 500 TABLET is not recommended for use if you have: Type 1 diabetes Diabetic ketoacidosis Acute or chronic metabolic acidosis A history of lactic acidosis Severe dehydration Before taking DAPARYL VM 500 TABLET, inform your doctor if you: Are scheduled for surgery, x-rays, or scanning procedures Have a vitamin B12 or folic acid deficiency
Drug Interactions
SA. Drug-Drug interactions: Before taking DAPARYL VM 500 TABLET, inform your doctor if you are taking any of the following medicines: Other diabetic medications (Ex. glyburide, insulin, and rosiglitazone) Water pills (diuretics) (Ex. furosemide) Birth control pills (Ex. ethinyl estradiol) Sympathomimetics (Ex. xylometazoline) Thyroid medicines (Ex, levothyroxine) Corticosteroids (Ex. prednisone) Anti-epileptic (Ex. phenytoin) Anti-lipemic (Ex. nicotinic acid) Anti-tubercular (Ex. isoniazid) Cardiovascular agents (Ex. nifedipine, digoxin, procainamide, quinidine, amiloride, and triamterene) Antimalarial (Ex. quinine) Anti-ulcers (Ex. cimetidine, ranitidine) Opioid analgesics (Ex. morphine) Antibiotics (Ex. trimethoprim, vancomycin) Blood thinners (Ex. warfarin) Overdosage: If you or anyone else takes too much of DAPARYL VM 500 TABLET, contact your doctor immediately or go to the nearest hospital right away. Symptoms of an overdose are muscle pain, mild and transient paraesthesia, fever, edema, and hypoglycemia. SYNOPSIS Drug : Dapagliflozin, Metformin, and Vildagliptin Pharmacological Category : Sodium-glucose cotransporter 2 (SGLT2), Biguanides, and Dipeptide peptidase-4 (DPP-4) inhibitors Therapeutic Indication : Type 2 Diabetes mellitus Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep DAPARYL VM 500 TABLET out of reach of children Store at a temperature below 25°C
Frequently Asked Questions
Common questions and answers about DAPARYL VM 500 Tablet 10's.
What is DAPARYL VM 500 TABLET used for?
It is used as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus (T2DM). Along with management, follow a regular exercise and diet plan as advised by the doctor to achieve better results.
Can I stop taking DAPARYL VM 500 TABLET without consulting your doctor?
No. Do not stop taking DAPARYL VM 500 TABLET without consulting your doctor because it may lead to unwanted side effects.
Can I consume alcohol while taking DAPARYL VM 500 TABLET?
Consumption of alcohol is not recommended while taking DAPARYL VM 500 TABLET. Consult your doctor for advice before taking the medicine.
Will taking a higher dose of DAPARYL VM 500 TABLET be more effective?
No, taking a higher dose of DAPARYL VM 500 TABLET will not be effective. Always take the dose as advised by your physician.
How should I take DAPARYL VM 500 TABLET?
Take DAPARYL VM 500 TABLET as advised by your physician. Swallow DAPARYL VM 500 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. Do not stop taking DAPARYL VM 500 TABLET without informing your doctor.
What are the common side effects of DAPARYL VM 500 TABLET?
The most common side effects of taking DAPARYL VM 500 TABLET are low sugar levels, painful urination, repetitive urination, inflammation of the penis (in men), and allergic reactions. Contact your doctor if any of the above side effects worsen or persist for a longer duration.
Can DAPARYL VM 500 TABLET be used in pregnant women?
DAPARYL VM 500 TABLET is not recommended for pregnant women. Consult your doctor before taking the medicine.
Can DAPARYL VM 500 TABLET be used for children?
The safety and effectiveness of DAPARYL VM 500 TABLET in children and adolescents have not been established. Consult your doctor before taking the medicine.
Who should not take DAPARYL VM 500 TABLET?
DAPARYL VM 500 TABLET is not recommended for use if you have Type 1 diabetes, diabetic ketoacidosis, acute or chronic metabolic acidosis, a history of lactic acidosis, severe dehydration, kidney disease or impairment, severe liver dysfunction, cardiovascular problems or cardiorespiratory insufficiency, or if you are allergic to dapagliflozin, metformin, or Vildagliptin. Consult your doctor before taking it.
What precautions must be taken while using DAPARYL VM 500 TABLET?
Before taking DAPARYL VM 500 TABLET, inform your doctor if you have vitamin B12 or folic acid deficiency, kidney disease, liver disease, heart attack or stroke, or if you are scheduled for surgery, x-ray, or scanning procedures.
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
15 Jul 2024