D Nil 5mg Tablet 10'S
Key Information
Generic Name
Generic Name Glibenclamide 5 mg Also Known As: Glyburide
Manufacturer
East West Pharma
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
D NIL 5MG TABLET contains Glibenclamide which belongs to the group of medicines called Antidiabetic agents. It is used to manage type 2 diabetes mellitus, when diet and physical exercise alone have not been able to control the blood sugar levels. Type 2 diabetes is a disease in which blood sugar levels are too high and the body either doesn't produce enough insulin, or it resists insulin. Symptoms include increased thirst, hunger, urination, feeling tired, blurred vision, numbness or tingling in the feet or hands, sores that do not heal, weight loss. Along with this management, your doctor might ask you to make certain lifestyle changes such as eating a healthy diet, not skipping meals & regular exercise. Prior to the management, your doctor may want you to take several blood tests to understand your existing condition. Avoid consumption of alcohol during management with D NIL 5MG TABLET, as it may worsen the
Uses
OF D NIL 5MG TABLET Manage type 2 diabetes mellitus
How It Works
D NIL 5MG TABLET lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This will only help lower blood sugar in bodies which produce insulin naturally.
Directions for Use
Take D NIL 5MG TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking D NIL 5MG TABLET are low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth and skin. USES OF D NIL 5MG TABLET Manage type 2 diabetes mellitus HOW D NIL 5MG TABLET WORKSD NIL 5MG TABLET lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This will only help lower blood sugar in bodies which produce insulin naturally. DIRECTIONS FOR USETake D NIL 5MG TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF D NIL 5MG TABLETCOMMON dizziness sweating palpitations hunger pangs dry mouth and skin RARE lower blood sugar than normal (hypoglycemia) decrease in the number of platelets (which increases risk of bleeding or bruising), white blood cells (which makes infections more likely), red blood cells (can pale the skin and cause weakness, breathlessness) Stop taking D NIL 5MG TABLET and contact your doctor immediately if you experience any of the following side effects: allergic (hypersensitivity) reactions (swelling of the lips, face, throat or tongue, skin rash, itching, hives and increased sensitivity to the sun, inflammation of blood vessels, serious reactions like difficulty breathing, fall in blood pressure and sometimes shock) abnormal liver function including yellowing of the skin and eyes (jaundice) problems with the bile flow (cholestasis), inflammation of the liver (hepatitis) or liver failure severe hypoglycemia including loss of consciousness or seizures
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedD NIL 5MG TABLET is not recommended for use in pregnancy. Consult your doctor before taking it. BREASTFEEDINGContraindicatedD NIL 5MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it. DRIVING AND USING MACHINESUse with CautionAvoid driving and using machines while taking D NIL 5MG TABLET as it may reduce your ability to concentrate or react if your blood sugar is lowered (hypoglycemia). ALCOHOLConsult your doctorAvoid drinking alcohol while taking D NIL 5MG TABLET as it may increase or decrease the blood sugar levels lowering the action of D NIL 5MG TABLET. KIDNEYConsult your doctorD NIL 5MG TABLET is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with severe kidney disorder. Consult your doctor before taking. LIVERConsult your doctorD NIL 5MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with severe liver disorder. Consult your doctor before taking. ALLERGYContraindicatedDo not take D NIL 5MG TABLET if you are allergic to Glibenclamide. HEART DISEASEConsult your doctorD NIL 5MG TABLET is not recommended for use in patients with coronary artery disease. D NIL 5MG TABLET should be used with caution in patients with other heart diseases. Consult your doctor before taking it. USE IN PEDIATRICSContraindicatedD NIL 5MG TABLET is not recommended for use in children and adolescents below 18 years of age. Consult your doctor before taking it. USE IN GERIATRICSUse with CautionD NIL 5MG TABLET should be used with caution in elderly patients above 65 years of age as they are sensitive to hypoglycemic action. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Consult your doctor before taking D NIL 5MG TABLET OTHERSD NIL 5MG TABLET is not recommended for use if you: have insulin dependent diabetes (type 1 diabetes mellitus) have diabetic ketoacidosis (a complication of diabetes with fatigue, nausea, frequent urination and muscular stiffness) are in a diabetic coma have serious problems with adrenal glands or pituitary glands have porphyria (abdominal pain, mental confusion, anxiety, fits, muscle pain etc.) Before taking D NIL 5MG TABLET, inform your doctor if you: are recovering from an injury, operation, infections with fever or stress are weak. You are more likely to suffer from hypoglycemia (low blood-sugar levels) have lactose deficiency (you are unable to digest milk or milk product) have G6PD- deficiency (enzyme which protects red blood cells) suffer from hormone induced disorders (of the thyroid glands, of the pituitary gland or adrenal cortex)
Drug Interactions
SA. Drug-Drug interactions: Before taking D NIL 5MG TABLET, inform your doctor if you are taking any of the following medicines: to manage pain and inflammation (Ex. phenylbutazone, glucocorticoids, azopropazone, oxyphenbutazone, aspirin) for diabetes mellitus (Ex. insulin or metformin) to support muscle build up (anabolics) to manage blood clotting (warfarin) to reduce weight (fenfluramine) to manage depression (Ex. fluoxetine, MAO inhibitors) to manage gout (allopurinol, probenecid, sulfinpyrazone) to manage cancer (Ex. cyclophosphamide, ifosfamide, trofosfamide) to manage bacterial, fungal infections (tetracyclines, chloramphenicol, fluconazole, miconazole, quinolones, clarithromycin) to manage hay fever (tritoqualine) to increase circulation (pentoxifylline) to manage urinary infections (such as sulfonamides) containing female sex hormones (estrogens, progestogens) to manage high blood pressure (bosentan, thiazide diuretics, betablockers, clonidine, guanethidine, diazoxide, glucagon, reserpine, ACE inhibitors), antiarrhythmic agents used to control abnormal heartbeat(disopyramide) to stimulate the thyroid gland (levothyroxine) to manage severe mental disorders (Ex. chlorpromazine, phenothiazine derivatives) adrenaline and sympathomimetics to manage high cholesterol levels (Ex. nicotinic acid, fibrates) to manage constipation (laxatives) to manage fits (phenytoin) for nervousness, sleep problems (barbiturates) to manage infections, tuberculosis (rifampicin) for increased pressure in the eye (azetazolamide) medicines used for stomach ulcers Overdosage: If you or anyone else accidentally take too much of D NIL 5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are characterized by faintness, feeling sick, cold sweats and palpitations. SYNOPSIS Drug : Glibenclamide Pharmacological Category : Sulfonylureas Therapeutic Indication : Type 2 diabetes mellitus Dosage Forms : Tablet MORE INFORMATION Keep D NIL 5MG TABLET out of reach of children Store at 25°C
Frequently Asked Questions
Common questions and answers about D Nil 5mg Tablet 10'S.
How should D NIL 5MG TABLET be used in elderly patients?
D NIL 5MG TABLET should be used with extra caution in elderly patients above 65 years of age, because they are at high risk of getting low blood sugar (hypoglycemic event).
Can D NIL 5MG TABLET cause hair loss?
No, hair loss is not seen with the use of D NIL 5MG TABLET. However, diabetes can lead to hair loss. Consult your doctor if you have too much hair loss as it could be due to other underlying conditions or a sign of diabetes getting worsened.
Can I stop taking D NIL 5MG TABLET?
No, D NIL 5MG TABLET should not be skipped as it can make your diabetes condition worse. If you miss the dose by mistake, take it when you remember immediately.
Can D NIL 5MG TABLET cause weight gain?
Yes, D NIL 5MG TABLET can cause weight gain. Closely monitor your diet and exercise regularly. Avoid skipping your meals as it can cause very low blood sugar levels and you may end up taking more sugar.
Article Information
Written By
ity (HPRA). [Revised in May 2016] [Accessed on 18th May 2022] https://www.hpra.ie/img/uploaded/swedocuments/2179143.PA0688_040_002.752e1eeb-1045-476a-97ac-9f7549199666.000001Product%20Leaflet%20Approved%205mg.160725.pdf 6. Teva Pharmaceuticals USA, Inc. Glyburide. [Revised on July 2021] [Accessed on 18th May 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=50d16f1d-c814-4411-8749-62561321ecce 7. Glibenclamide.MedlinePlus. [Revised on May 2021] [Accessed On 18th May 2022] https://medlineplus.gov/diabetestype2.html 8. Glyburide.MedlinePlus.[Revised in October 2018] [Accessed on 18th May 2022] https://medlineplus.gov/druginfo/meds/a684058.html USEFUL DIAGNOSTIC TESTS Blood tests (glycated hemoglobin test, random blood sugar test, fasting blood sugar test) Oral glucose tolerance test AUTHOR DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
28 Oct 2023