CYCLOPYURIN 25 Capsule 10's

Auto Immune Disease (210)Rx required

Key Information

Generic Name

Generic Name Cyclosporin 25 mg Also Known As: Ciclosporin

Manufacturer

PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED (Generics)

Variant

10 Capsule(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT CYCLOPYURIN 25 CAPSULECYCLOPYURIN 25 CAPSULE contains Cyclosporine which belongs to the group of medicines called Immunosuppressants. It is used to manage graft rejection in patients undergoing transplantation of any organ, bone marrow or stem cells. It can also be used to manage various auto-immune disease conditions such as psoriasis, atopic dermatitis (or eczema), rheumatoid arthritis (joint inflammation), nephrotic syndrome (a kidney disease) or eye inflammation (such as endogenous uveitis, including Behçet's uveitis). It is mostly used in combination with other immune suppressants (such as azathioprine) to achieve maximum benefits. Take CYCLOPYURIN 25 CAPSULE regularly as instructed by your doctor. While undergoing therapy with CYCLOPYURIN 25 CAPSULE your doctor will periodically monitor your blood pressure, blood cholesterol levels, liver and kidney functions to avoid the risk of

Uses

OF CYCLOPYURIN 25 CAPSULE Prevents graft rejection following organ transplantation Manage auto-immune skin diseases such as psoriasis or atopic dermatitis Manage rheumatoid arthritis (joint inflammation) Manage nephrotic syndrome (a kidney disease) Manage eye inflammation (such as endogenous uveitis, including Behçet's uveitis)

How It Works

CYCLOPYURIN 25 CAPSULE is an immunosuppressive agent. It works by blocking the release of certain chemicals in the body (such as T-cells, interleukins and cytokines) that triggers the immune response. This action suppresses your body’s immune functions and enables your body to accept the newly transplanted organ. It also stops the abnormal immune response in the body and manages your body from attacking its own cells.

Directions for Use

Take CYCLOPYURIN 25 CAPSULE as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking CYCLOPYURIN 25 CAPSULE without consulting your doctor.

Side Effects

infections (such as fever or sore throat). You must also inform your doctor if you have hepatitis C infection, fits, low blood magnesium levels, gout, alcohol dependence or if you are about to receive any vaccinations as a precaution. CYCLOPYURIN 25 CAPSULE is not recommended for use in patients with severe uncontrollable infections, any types of cancer or severe high blood pressure. Do not take CYCLOPYURIN 25 CAPSULE without consulting your doctor if you are pregnant or breastfeeding. Avoid consuming grapefruit or drinking grapefruit juice while taking CYCLOPYURIN 25 CAPSULE as it may increase the risk of side effects. The most common side effects of taking CYCLOPYURIN 25 CAPSULE are increase in blood sugar levels, increase in blood cholesterol levels, increased blood potassium levels, high blood pressure, headache, loss of appetite, acne, hot flushes, tiredness, excessive facial hair and low blood magnesium levels in blood. Consult your doctor if any of these side effects worsen. USES OF CYCLOPYURIN 25 CAPSULE Prevents graft rejection following organ transplantation Manage auto-immune skin diseases such as psoriasis or atopic dermatitis Manage rheumatoid arthritis (joint inflammation) Manage nephrotic syndrome (a kidney disease) Manage eye inflammation (such as endogenous uveitis, including Behçet's uveitis) HOW CYCLOPYURIN 25 CAPSULE WORKSCYCLOPYURIN 25 CAPSULE is an immunosuppressive agent. It works by blocking the release of certain chemicals in the body (such as T-cells, interleukins and cytokines) that triggers the immune response. This action suppresses your body’s immune functions and enables your body to accept the newly transplanted organ. It also stops the abnormal immune response in the body and manages your body from attacking its own cells. DIRECTIONS FOR USETake CYCLOPYURIN 25 CAPSULE as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking CYCLOPYURIN 25 CAPSULE without consulting your doctor. SIDE EFFECTS OF CYCLOPYURIN 25 CAPSULECOMMON high blood pressure headache, shakiness nausea, vomiting, loss of appetite, stomach pain, diarrhoea acne, hot flushes, fever, tiredness excessive facial hair high blood cholesterol levels high blood sugar levels tingling sensation in the body muscle spasm, swollen gums high blood levels of uric acid or potassium low levels of magnesium in blood UNCOMMON lack of sleep oedema, weight gain RARE inflammation of the pancreas, severe upper stomach pain menstrual irregularities, breast enlargement in men Stop taking CYCLOPYURIN 25 CAPSULE and contact your doctor immediately if you experience any of the following side effects: signs of infections (such as fever or sore throat) signs of brain infection called progressive multifocal leukoencephalopathy (such as vision changes, loss of coordination, being clumsy, memory loss, problems in speaking or understanding, muscle weakness) brain problems (causing seizures, confusion, disorientation, lack of response, behavioural changes, agitation, sleeplessness, vision changes, paralysis, stiff neck, loss of coordination with or without unusual speech or eye movements) swelling at the back of the eye with blurred vision signs of liver problems (such as yellow skin and eyes, nausea, loss of appetite and dark urine) low urine output, kidney problems low level of red blood cells or platelets (causing pale skin, tiredness, breathlessness, having dark urine, bruising or bleeding with no obvious reasons, confusion, disorientation, being less alert and having kidney problems)

Warnings & Precautions

& PRECAUTIONSPREGNANCYCYCLOPYURIN 25 CAPSULE is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. BREASTFEEDINGCYCLOPYURIN 25 CAPSULE may pass through the breast milk. Therefore, it is not recommended for use in breastfeeding woman. However, consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines if your ability is affected by CYCLOPYURIN 25 CAPSULE. ALCOHOLAvoid consumption of alcohol while taking CYCLOPYURIN 25 CAPSULE as it might worsen your condition. KIDNEYCYCLOPYURIN 25 CAPSULE is not recommended for use in patients with other kidney problems (except for nephrotic syndrome). Therefore, consult your doctor before taking it. LIVERCYCLOPYURIN 25 CAPSULE should be used with caution in patients with liver problems (including Hepatitis C infection). Therefore, consult your doctor before taking it. ALLERGYTalk to your doctor before taking CYCLOPYURIN 25 CAPSULE if you are allergic to cyclosporine. OTHERSCYCLOPYURIN 25 CAPSULE is not recommended for use if you: have severe infections in the body which is unable to control have any type of cancer have uncontrollably high blood pressure Before taking CYCLOPYURIN 25 CAPSULE inform your doctor if you: have any signs of infection, such as fever or sore throat have low levels of magnesium in the body have high blood potassium levels have gout (joint pain caused due to fluid accumulation) are about to receive any vaccination have or ever had alcohol-related problems have epilepsy Use in paediatrics: CYCLOPYURIN 25 CAPSULE should only be used to manage nephrotic syndrome in children. It is generally not recommended for managing graft rejection or for managing other auto-immune disease condition apart from nephrotic syndrome in children. Therefore, consult your doctor before taking it. Use in geriatrics: CYCLOPYURIN 25 CAPSULE should be used with caution in elderly patients. Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.

Drug Interactions

SA. Drug - Drug interactions: Before taking CYCLOPYURIN 25 CAPSULE, inform your doctor if you are taking any of the following medicines such as: St. John’s Wort (an herbal medicine used to manage depression) dabigatran etexilate (a medicine used to manage blood clots after surgery) bosentan or aliskiren (medicines used to manage high blood pressure) vaccines medicines that can increase blood potassium levels in the body (such as potassium supplements or potassium-sparing diuretics (Ex. amiloride, triamterene or spironolactone)) methotrexate (a medicine used to manage cancer and severe rheumatoid arthritis) medicines used to manage bacterial infections (Ex. erythromycin, azithromycin, gentamycin, tobramycin, ciprofloxacin) medicines used to manage fungal infections (Ex. voriconazole, itraconazole, terbinafine, amphotericin B) medicines used for heart problems or high blood pressure (Ex. diltiazem, nicardipine, verapamil, digoxin, amiodarone) metoclopramide (a medicine used to stop nausea and vomiting) danazol (a medicine used to manage overgrowth in the uterus) oral contraceptives (birth control pills) Ex. ethinylestradiol medicines used to manage gout (Ex. colchicine, allopurinol) medicines used to manage gallstones (Ex. ursodiol) medicines used to manage leukaemia and other cancers (Ex. imatinib, melphalan, etoposide, doxorubicin) barbiturates (used to reduce anxiety and to induce sleep) Ex. phenobarbital medicines used to manage epilepsy (Ex. carbamazepine, phenytoin, cannabidiol) octreotide (a medicine used to manage hormonal disorder, (acromegaly) and tumours) orlistat (a medicine that helps in weight loss) ticlopidine (a medicine used to manage blood clots due to platelet aggregation) other medicines used to supress immune system (Ex. everolimus, sirolimus, tacrolimus) medicine used to reduce pain and inflammation Ex. diclofenac medicines used to lower cholesterol levels (Ex. fenofibrate, atorvastatin, Fluvastatin) medicines used to manage tuberculosis (Ex. isoniazid, rifampicin) medicines used to manage HIV infections (Ex. acyclovir, ritonavir, nelfinavir, saquinavir, efavirenz, etravirine, nevirapine) medicines used to manage hepatitis C infection (Ex. telaprevir, boceprevir, the combination ombitasvir/paritaprevir/ritonavir with or without dasabuvir, elbasvir/grazoprevir and glecaprevir/pibrentasvir) medicines used to manage gastric problems (Ex. omeprazole, cimetidine, magnesium hydroxide, aluminum hydroxide) trimethoprim or cotrimoxazole (used to manage bacterial infections) corticosteroids (used to manage allergic or autoimmune diseases) Ex. prednisolone, methylprednisolone medicines used to manage diabetes (Ex. repaglinide) B. Drug – food interactions Avoid consuming grapes or grapefruit juice while taking CYCLOPYURIN 25 CAPSULE as it may increase the risk of side effects. Overdosage: If you or anyone else accidentally took more CYCLOPYURIN 25 CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include vomiting, drowsiness, headache, fast heartbeat and kidney damage. SYNOPSIS Drug : Cyclosporine Pharmacological Category : Calcineurin inhibitors Therapeutic Indication : Graft rejection, Autoimmune diseases Dosage Forms : Tablet, Capsule, Injection, Infusion, Oral Solution, Oral Suspension, Eye Drops, Ophthalmic Emulsion MORE INFORMATION Keep CYCLOPYURIN 25 CAPSULE out of reach of children Store CYCLOPYURIN 25 CAPSULE at room temperature

Article Information

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Written By

DETAILS Written By Srilekha. R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

22 Nov 2022

Tags

#auto immune disease (210)#generic name cyclosporin 25 mg also known as: ciclosporin