CTD AZ 40/12.5mg Tablet 10'S
Key Information
Generic Name
Generic Name Azilsartan 40 mg+Chlorthalidone 12.5 mg
Manufacturer
Ipca Laboratories Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTIONCTD AZ 40/12.5MG is a fixed-dose combination of Azilsartan and Chlorthalidone which belongs to the group of medicines called Antihypertensive agents. It is used in adults to manage hypertension. Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several organs, like heart, kidney, or brain. Azilsartan is an angiotensin II receptor blocker. It acts by relaxing the blood vessels supplying the vital organs. Chlorthalidone is a thiazide-diuretic. It acts by increasing the removal of water and certain electrolytes (sodium and chloride) from the body in the form of urine which eventually reduces blood volume. Collectively, they improve blood flow through the blood vessels and reduces the elevated blood pressure. While undergoing therapy with CTD AZ 40/12.5MG your doctor will regularly monitor your blood pressure, kidney function, blood sugar, cholesterol or uric acid levels and electrolyte profile (sodium, potassium, and magnesium levels) to avoid the risk of unwanted
Uses
OF CTD AZ 40/12.5MG Manages hypertension in adults
How It Works
CTD AZ 40/12.5MG effectively controls blood pressure. It contains azilsartan and chlorthalidone. Azilsartan blocks the actions of a peptide hormone called angiotensin-II that increases blood pressure. This makes the blood vessels to relax and improves blood flow within them. Chlorthalidone increases the excretion of water and electrolytes (sodium and chloride) from the body in the form of urine. This reduces blood volume which makes the blood to be pumped easier by the heart with less pressure. Collectively they reduces blood pressure.
Directions for Use
Take CTD AZ 40/12.5MG as directed by the physician. Swallow CTD AZ 40/12.5MG with a glass of water. Do not crush or chew the medicine. CTD AZ 40/12.5MG can be taken with or without meals. Your doctor will decide the correct dose and for how long CTD AZ 40/12.5MG must be taken depending upon your age, body weight and disease condition. Do not stop taking CTD AZ 40/12.5MG without consulting your doctor.
Side Effects
CTD AZ 40/12.5MG are low blood potassium levels, tiredness, or muscle spasms. Consult your doctor if any of these side effect worsens. USES OF CTD AZ 40/12.5MG Manages hypertension in adults HOW CTD AZ 40/12.5MG WORKSCTD AZ 40/12.5MG effectively controls blood pressure. It contains azilsartan and chlorthalidone. Azilsartan blocks the actions of a peptide hormone called angiotensin-II that increases blood pressure. This makes the blood vessels to relax and improves blood flow within them. Chlorthalidone increases the excretion of water and electrolytes (sodium and chloride) from the body in the form of urine. This reduces blood volume which makes the blood to be pumped easier by the heart with less pressure. Collectively they reduces blood pressure. DIRECTIONS FOR USETake CTD AZ 40/12.5MG as directed by the physician. Swallow CTD AZ 40/12.5MG with a glass of water. Do not crush or chew the medicine. CTD AZ 40/12.5MG can be taken with or without meals. Your doctor will decide the correct dose and for how long CTD AZ 40/12.5MG must be taken depending upon your age, body weight and disease condition. Do not stop taking CTD AZ 40/12.5MG without consulting your doctor. SIDE EFFECTS OF CTD AZ 40/12.5MGCOMMON feeling dizzy or faint with or without changing position diarrhea, nausea, loss of appetite, stomach upset feeling tired muscle spasms swelling of the hands, ankles, or feet skin rash, itching impotence in men worsening of blood cholesterol hypokalaemia (decrease in serum potassium levels) increase in creatinine and uric acid levels UNCOMMON fainting sense of tingling and numbness vomiting gout (pain and swelling in the joints) anaemia (low RBC count) worsening of diabetes migraine (severe headache on one side) RARE abnormal heartbeat yellowing of the skin or eyes caused by liver problems increased photosensitivity (sensitivity to sunlight) problems in breathing due to fluid build-up in the lungs stomach pain, constipation Stop taking CTD AZ 40/12.5MG and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing or swallowing) decrease in vision
Warnings & Precautions
& PRECAUTIONSPREGNANCYCTD AZ 40/12.5MG is strictly not recommended for use in pregnant women as it may cause serious harm to the unborn baby. Therefore, consult your doctor before taking it. Women taking CTD AZ 40/12.5MG must inform their doctor immediately if they become pregnant while undergoing therapy with CTD AZ 40/12.5MG. BREASTFEEDINGCTD AZ 40/12.5MG is not recommended for use in breast feeding women. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any tools or machines if you feel dizzy after taking CTD AZ 40/12.5MG. ALCOHOLAvoid consumption of alcohol while undergoing therapy CTD AZ 40/12.5MG as it may make you feel dizzy or drowsy. KIDNEYCTD AZ 40/12.5MG is not recommended for use in patients with severe kidney diseases or problems in passing urine. It should be used with caution in patients with other kidney problems (such as dialysis or any recent kidney transplant). Therefore, consult your doctor before taking it. LIVERCTD AZ 40/12.5MG is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it. ALLERGYDo not take CTD AZ 40/12.5MG if you are allergic to Azilsartan or Chlorthalidone. HEART DISEASECTD AZ 40/12.5MG should be used with caution in patients with heart problems (such as heart attack or failure, low blood pressure, narrowing or heart valves or increase in thickness of heart muscles). Therefore, consult your doctor before taking it. OTHERSCTD AZ 40/12.5MG is not recommended for use if you: have low levels of sodium in the blood that cannot be corrected despite management have high blood calcium levels have gout or high levels of uric acid in the blood have diabetes Before taking CTD AZ 40/12.5MG, inform your doctor if you: have ever had a stroke have muscle pains, cramps, or weakness are severely dehydrated or have conditions such as nausea, vomiting or diarrhoea that may make you dehydrate very easily have dry mouth, thirst, or feeling tired have primary hyperaldosteronism (problems in adrenal gland) Use in pediatrics: CTD AZ 40/12.5MG should not be used in children and adolescents (below 18 years) due to lack of safety data. Therefore, consult your doctor before taking it. Use in geriatrics: CTD AZ 40/12.5MG should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug-Drug Interaction: Before taking CTD AZ 40/12.5MG, inform your doctor if you are taking any of the following medicines such as: other medicines that can control blood pressure (such as captopril, enalapril, lisinopril, ramipril, valsartan, telmisartan, irbesartan or aliskiren) lithium (a medicine used to manage mental illnesses) non-steroidal anti-inflammatory drugs (used for pain relief) such as ibuprofen, diclofenac, celecoxib, or aspirin medicines used to increase potassium levels in the blood such as potassium supplements, or potassium-sparing medicines (such as spironolactone, aldosterone) medicines that can reduce blood potassium levels such as amphotericin, carbenoxolone, prednisone, or ACTH heparin (a medicine used for blood thinning) medicines used to manage diabetes (such as metformin, glimepiride) medicines used to manage gout (Ex. allopurinol, probenecid) medicines used to manage asthma (Ex. salbutamol, budesonide, formoterol) digitalis (a medicine used to correct abnormal heart rhythm) anticholinergics (used to reduce muscle spasms and to increase heart functions) such as atropine amantadine (a medicine used to manage viral infections or Parkinson´s disease) cholestyramine (a medicine used to reduce blood cholesterol levels) ciclosporin (a medicine used to suppress immune functions or to prevent graft rejection) medicines used to manage cancer (Ex. cyclophosphamide or methotrexate) Vitamin D and calcium supplements Overdosage: If you or anyone else accidentally took more CTD AZ 40/12.5MG, consult your doctor immediately. Symptoms of overdosage might include feeling dizzy or faint. SYNOPSIS Drug : Azilsartan, Chlorthalidone Pharmacological Category : Angiotensin Receptor Blockers, Thiazide Diuretics Therapeutic Indication : Hypertension Dosage Forms : Tablet MORE INFORMATION Keep CTD AZ 40/12.5MG out of reach to children Store CTD AZ 40/12.5MG at room temperature
Article Information
Written By
ity (HPRA). [Revised in December 2021] [Accessed on 23rd June 2022] https://www.hpra.ie/img/uploaded/swedocuments/cf80a3a8-cab0-4606-85da-ef6eb00fe5ee.pdf 5. Takeda Pharmaceuticals America, Inc. U.S. Food & Drug Administration. [Revised in December 2011] [Accessed on 23rd June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202331lbl.pdf USEFUL DIAGNOSTIC TESTS Kidney Function Tests
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