Cordarone Injection 3ml
Key Information
Generic Name
Generic Name Amiodarone 50 mg
Manufacturer
Sanofi India Limited
Country of Origin
India
Detailed Information
Introduction
s cannot be given. Your doctor might want you to keep out of direct sunlight while receiving CORDARONE INJECTION and for a few months after you have finished receiving it. Avoid consumption of alcohol and grapefruit juice during management with CORDARONE INJECTION. CORDARONE INJECTION is not recommended for use if you have severe breathing and blood circulation problems, slower than usual heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart block. It is also not recommended if you have other problems with your heartbeat without a pacemaker fitted, are going to have a heart transplantation, have ever had thyroid problems or low blood pressure. Before receiving CORDARONE INJECTION, inform your doctor if you have heart failure or weak heart (cardiomyopathy), liver, kidney, thyroid, lung problems or asthma, require oxygen management, are to undergo a general anesthetic, or have eyesight problems (optic neuritis). Also inform your doctor if you are about to have any surgery, blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever (Stevens-Johnson syndrome), layers of the skin skin peeling off to leave large areas of raw exposed skin over the body (Toxic Epidermal Necrolysis). CORDARONE INJECTION is not recommended for pregnant or breastfeeding women. CORDARONE INJECTION is contraindicated in premature babies or neonates and should be used with caution in infants and children up to 3 years old. Safety data has not been established in children and adolescents above 3 years of age. CORDARONE INJECTION should be used with caution in elderly patients above 60 years of age. The most common
Uses
OF CORDARONE INJECTIONIt is usually used in hospitals when tablets cannot be given and a quick response is needed to manage: sudden fast or uneven heartbeats (atrial flutter or atrial fibrillation) when other medicines either have not worked or cannot be used Wolff-Parkinson-White Syndrome
How It Works
CORDARONE INJECTION works by blocking certain electrical signals and reducing the excitability of cardiac tissues which manages the initiation and conduction of any new impulses in the heart that cause irregular heartbeats, thus making your heartbeat return to normal.
Directions for Use
CORDARONE INJECTION must be given by a doctor or nurse into the vein as an intravenous injection or infusion. Your doctor will decide the correct dose and duration of CORDARONE INJECTION for you depending upon your age, body weight and disease condition.
Side Effects
receiving CORDARONE INJECTION are blurred eyesight, rashes, muscle weakness, difficulty sleeping, nightmares. Consult your doctor if any of the symptoms worsen. USES OF CORDARONE INJECTIONIt is usually used in hospitals when tablets cannot be given and a quick response is needed to manage: sudden fast or uneven heartbeats (atrial flutter or atrial fibrillation) when other medicines either have not worked or cannot be used Wolff-Parkinson-White Syndrome HOW CORDARONE INJECTION WORKSCORDARONE INJECTION works by blocking certain electrical signals and reducing the excitability of cardiac tissues which manages the initiation and conduction of any new impulses in the heart that cause irregular heartbeats, thus making your heartbeat return to normal. DIRECTIONS FOR USECORDARONE INJECTION must be given by a doctor or nurse into the vein as an intravenous injection or infusion. Your doctor will decide the correct dose and duration of CORDARONE INJECTION for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF CORDARONE INJECTIONCOMMON blurred eyesight or seeing a colorful halo in dazzling light tanning more easily in the sun red rash with itching slightly slower heartbeat, reduced blood pressure (dizziness, light-headedness, fainting) reactions at injection site (swelling, pain, redness, infection, blue or gray marks on parts of your skin exposed to sunlight, especially the face) hyperthyroidism (feeling extremely restless or agitated, weight loss, too much sweating and unbearable heat) hypothyroidism (feeling extremely tired or weak, weight gain, unbearable cold, constipation and muscle pain) shivering when you move your arms or legs, weak muscles nightmares, sleep problems reduced sex drive UNCOMMON numbness, weakness, tingling or burning feelings in any part of your body RARE hypersensitivity reactions (due to an excipient- benzyl alcohol) Stop receiving CORDARONE INJECTION and consult your doctor immediately if you experience any of the following side effects: allergic reaction (rash, difficulty swallowing or breathing, swollen eyelids, face, lips, throat or tongue) very slow or no heartbeats (dizziness, tiredness, breathlessness) more uneven or unstable heartbeats (can lead to heart attack) liver problems or damage (yellowing of the skin or eyes, tiredness, nausea, loss of appetite, stomach pain or fever) lung inflammation (breathlessness or tightness in the chest, coughing which will not go away, wheezing or weight loss) torsade de pointes (life-threatening irregular heartbeat) Stevens-Johnson syndrome (blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, and flu-like symptoms) toxic epidermal necrolysis (severe blistering rash in which layers of the skin may peel off, feeling generally unwell, chills and muscle pain) bullous dermatitis (fluid filled blisters on the skin) problem with your brain (headache (usually worse in the morning or happens after coughing or straining), nausea, fits, confusion)) flu like symptoms and a rash on the face followed by an extended rash with a high temperature, enlarged lymph nodes (DRESS)
Warnings & Precautions
& PRECAUTIONSPREGNANCYCORDARONE INJECTION is not recommended for use in pregnant women or women planning to have a baby, except in life-threatening circumstances. Consult your doctor before receiving it. BREASTFEEDINGCORDARONE INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving it. DRIVING AND USING MACHINESCORDARONE INJECTION may affect your ability to drive or use machines. Consult your doctor before receiving it. ALCOHOLLimit the consumption of alcohol during management with CORDARONE INJECTION. Consult your doctor before receiving it. KIDNEYCORDARONE INJECTION should be received with caution in patients with kidney problems. Consult your doctor before receiving CORDARONE INJECTION. LIVERCORDARONE INJECTION should be received with caution in patients with liver problems. Consult your doctor before receiving it. ALLERGYDo not receive CORDARONE INJECTION if you are allergic to Amiodarone or any of the other ingredients of this medicine. Consult your doctor before receiving it. LUNGSCORDARONE INJECTION is not recommended for use if you have severe breathing problems. CORDARONE INJECTION should be received with caution in patients with asthma, or any other lung diseases. Consult your doctor before receiving it. HEART DISEASECORDARONE INJECTION should not be given in patients with slower than usual heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart block, other problems with your heartbeat without a pacemaker fitted, are going to have a heart transplantation or have low blood pressure. CORDARONE INJECTION should be used cautiously in patients with heart failure or weak heart (cardiomyopathy) or low blood pressure. Consult your doctor before receiving CORDARONE INJECTION. OTHERSCORDARONE INJECTION is not recommended for use if you: have or have earlier had any thyroid problems have blood circulation problems Before receiving CORDARONE INJECTION, inform your doctor if you: have any issues with your eyesight (optic neuritis) are about to have any surgery have Stevens-Johnson syndrome (blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever) have toxic epidermal necrolysis (severe blistering rash in which layers of the skin may peel off, feeling generally unwell, fever, chills and muscle pain) require oxygen management or are to undergo a general anesthetic have thyroid problems Use in pediatrics: CORDARONE INJECTION is contraindicated in premature babies or neonates and should be used with caution in infants and children up to 3 years old. Safety data has not been established in children and adolescents above 3 years of age. Use in geriatrics: CORDARONE INJECTION should be used with caution in elderly patients aged above 60 years. Consult your doctor before receiving CORDARONE INJECTION.
Drug Interactions
SA. Drug - Drug interactions: Before receiving CORDARONE INJECTION, inform your doctor if you are taking any of the following medicine: other medicines used to manage uneven heartbeats (Ex. sotalol, quinidine, procainamide, disopyramide, flecainide, bretylium or amiodarone tablets) medicines used to improve blood supply to the brain (Ex. vincamine). medicines used to manage other mental illnesses like depression (Ex. sultopride, sulpiride, pimozide, lithium, doxepin, maprotiline, amitriptyline, clomipramine, dosulepin, imipramine, lofepramine, nortriptyline or trimipramine) medicines used to manage infections (Ex. intra-venous erythromycin, co-trimoxazole, moxifloxacin, pentamidine, clarithromycin, ciprofloxacin, ofloxacin, levofloxacin or injections of pentamide) medicines used to manage schizophrenia (Ex. chlorpromazine, fluphenazine, thioridazine, haloperidol, sertindole or amisulpride) medicines used to manage hay fever, rashes or other allergies (Ex. terfenadine, astemizole or mizolastine) medicines used to manage malaria (Ex. quinine, mefloquine, chloroquine or halofantrine) medicines used to manage hepatitis C (Ex. sofosbuvir, daclatasvir, simeprevir or ledispasvir) medicine used to manage heart problems (such as high blood pressure, chest pain or high cholesterol) (Ex. propranolol, flecainide, diltiazem, verapamil, furosemide, simvastatin, atorvastatin or digitalis) medicines used to manage digestive problems like constipation (Ex. cisapride, droperidol, bisacodyl or senna) medicines used to manage fungal infection (Ex. amphotericin IV) medicines used to manage inflammation (Ex. hydrocortisone, betamethasone or prednisolone) medicines which may change the levels of potassium or magnesium in your blood Ex. diuretics (water tablets), steroid tablets medicines for high cholesterol called statins (e.g. simvastatin or atorvastatin). medicines used to manage fits (Ex. phenytoin) medicines used during surgery (Ex. lidocaine, midazolam, triazolam or high dose oxygen) medicines used to test some hormone problems (Ex. tetracosactide) medicines used to manage rejection of transplants (Ex. ciclosporin, tacrolimus and sirolimus) medicines used to manage erection problems (Ex. sildenafil, tadalafil or vardenafil) medicines used to manage pain or migraines (Ex. fentanyl or ergotamine) medicines used to stop your blood from clotting (Ex. warfarin, dabigatran) medicine used in some blood tests or in management of Crohn’s disease (Ex. tetracosactrin) B. Drug - Food interaction: Avoid drinking grapefruit juice while receiving CORDARONE INJECTION as it may increase the risk of side effects. Overdosage: CORDARONE INJECTION will be given to you only by a doctor or nurse in a hospital and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms like feeling dizzy, faint, sick, tired, confused or abnormally slow or fast heartbeats, contact your doctor immediately. SYNOPSIS Drug : Amiodarone Pharmacological Category : Antiarrhythmic Therapeutic Indication : Arrhythmias, Wolff-Parkinson-White Syndrome Dosage Forms : Tablet, Injection MORE INFORMATION Keep CORDARONE INJECTION out of reach of children Do not store above 25°C
Article Information
Written By
DETAILS Written By Dr. Shruthi M R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
12 Jan 2023