Combiflam Tablet 20'S
Key Information
Generic Name
Generic Name Ibuprofen 400 mg+Paracetamol 325 mg
Manufacturer
Sanofi India Limited
Variant
20 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
COMBIFLAM TABLET is a combination of Ibuprofen and Paracetamol, which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs (NSAIDs) and Analgesics respectively. It is used to manage minor aches and pains such as headaches, toothaches, muscular aches, backaches, pain due to inflammation and for reduction of fever due to any of the above conditions in adults and children aged 12 years and above. Analgesics help to reduce fever. Before taking this medicine, inform your doctor if you are allergic (hypersensitive) to ibuprofen, paracetamol, or any other NSAIDs such as aspirin. Also tell the doctor if you have, liver, kidney, or heart problems. Pregnant and breastfeeding women should consult their doctors before taking the medicine. The most common
Uses
OF COMBIFLAM TABLET It is used to manage minor aches and pains such as headaches, toothaches, muscular aches, backaches and pain due to inflammation and for reduction of fever due to any of the above conditions
How It Works
COMBIFLAM TABLET collectively works as non-steroidal anti-inflammatory (NSAIDs) and analgesic agent which works by inhibiting the effect of a chemical messenger called prostaglandins that are responsible for producing pain and inflammation. This blocks the Cox-enzyme (a natural substance produced in our body) thereby, restricting its action, which reduces the inflammation and pain at the site.
Directions for Use
Take COMBIFLAM TABLET as advised by your physician. It can be taken with or without food. For Tablet, Capsule: Swallow COMBIFLAM TABLET with a glass of water. Do not crush or chew the medicine. For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
Side Effects
the above side effects worsen or persist for a longer duration. USES OF COMBIFLAM TABLET It is used to manage minor aches and pains such as headaches, toothaches, muscular aches, backaches and pain due to inflammation and for reduction of fever due to any of the above conditions HOW COMBIFLAM TABLET WORKSCOMBIFLAM TABLET collectively works as non-steroidal anti-inflammatory (NSAIDs) and analgesic agent which works by inhibiting the effect of a chemical messenger called prostaglandins that are responsible for producing pain and inflammation. This blocks the Cox-enzyme (a natural substance produced in our body) thereby, restricting its action, which reduces the inflammation and pain at the site. DIRECTIONS FOR USETake COMBIFLAM TABLET as advised by your physician. It can be taken with or without food. For Tablet, Capsule: Swallow COMBIFLAM TABLET with a glass of water. Do not crush or chew the medicine. For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. SIDE EFFECTS OF COMBIFLAM TABLETCOMMON dizziness drowsiness indigestion heartburn changes in kidney function higher levels of liver enzymes excessive sweating stomach pain nausea, vomiting diarrhoea UNCOMMON headache constipation skin rash swelling of the face itching reduction in blood cells increase in platelets numbness RAREStop taking this medicine and contact your doctor immediately if you experience any of the following side effects: signs of intestinal bleeding, symptoms include vomiting blood or looks like coffee granules, blood in the stools or black tarry stools signs of inflammation of the brain lining, symptoms include stiff neck, prolonged fever, feeling disoriented asthma, wheezing, shortness of breath sudden pain or tightness in the chest signs of a severe allergic reaction, symptoms include, swelling of the face, lips, tongue, throat, making breathing and swallowing difficult severe skin blistering or skin peeling, skin becomes sensitive to light yellowing of the skin and eyes swelling of other parts of the body signs of kidney problems, symptoms include an increase or decrease in urination, swollen legs, water retention
Warnings & Precautions
& PRECAUTIONSPREGNANCYCOMBIFLAM TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine. BREASTFEEDINGCOMBIFLAM TABLET is not recommended for breastfeeding mothers. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESCOMBIFLAM TABLET should be taken with caution while driving or using machinery, as the medicine could cause dizziness, avoid driving or using heavy machinery in such conditions. ALCOHOLConsumption of alcohol should be avoided during management with COMBIFLAM TABLET. KIDNEYCOMBIFLAM TABLET should be used with caution for patients suffering with kidney problems. Consult your doctor before taking this medicine. LIVERCOMBIFLAM TABLET is not recommended in patients having liver damage. Consult your doctor before taking the medicine. ALLERGYDo not take COMBIFLAM TABLET, if you are allergic (hypersensitive) to Ibuprofen or Paracetamol or any other ingredients of this medicine. LUNGSCOMBIFLAM TABLET is not recommended in patients with a history of bronchial asthma. Consult your doctor before taking the medicine. HEART DISEASECOMBIFLAM TABLET is not recommended in patients with a history of heart attack, bypass surgery, block in arteries, or ischemia arteries. Consult your doctor before taking the medicine. OTHERSBefore taking COMBIFLAM TABLET tell your doctor if you: have systemic lupus erythematosus (SLE) (condition of the immune system affecting connective tissue resulting in joint pain, skin changes and disorder of other organs) have a blood clotting disorder have a gastrointestinal disorder, ulceration, bleeding in the stomach or duodenum Use in pediatrics: COMBIFLAM TABLET is not recommended for children and adolescents under 12 years of age. Consult your doctor before taking the medicine. Use in geriatrics: COMBIFLAM TABLET should be used with caution in elderly patients. Consult your doctor before taking the medicine.
Drug Interactions
SA. Drug-Drug interactions: Before taking COMBIFLAM TABLET, inform your doctor if you are taking any of the following medicine: other NSAIDs (Ex. naproxen, diclofenac) anti-hypertensives to reduce hypertension (Ex. atenolol, propranolol) diuretics promotes diuresis (Ex. hydrochlorothiazide, furosemide) cardiac glycosides to manage heart failure (Ex. digoxin, digitoxin) lithium to manage depression or anxiety methotrexate to manage cancer ciclosporin to manage rheumatoid arthritis mifepristone is used for abortion corticosteroids manage inflammation and allergy (Ex. prednisone, dexamethasone) anti-coagulants manage blood clots (Ex. warfarin) quinolone antibiotics are used to manage bacterial infections (Ex. ciprofloxacin, levofloxacin) anti-platelet agents and selective serotonin reuptake inhibitors to manage depression (Ex. citalopram, fluoxetine) immunosuppressant (Ex. tacrolimus) zidovudine to manage human immunodeficiency (HIV infection) cholestyramine to manage high cholesterol levels metoclopramide and domperidone to manage nausea and vomiting chloramphenicol to manage serious bacterial infections promethazine used to manage stomach ulcers Overdosage: If you or anyone else accidentally took too much of COMBIFLAM TABLET, consult your doctor immediately. Symptoms includes nausea, upset stomach, vomiting and gastric irritation, feel light-headed, dizzy, or drowsy, excitability, convulsions, blood in urine. SYNOPSIS Drug : Ibuprofen and Paracetamol Pharmacological Category : Anti-inflammatory and Analgesics Therapeutic Indication : Manages pain and Fever Dosage Forms : Tablet, Syrup MORE INFORMATION Keep out of reach of children Store at room temperature
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
25 Nov 2022