CELEBREX 100mg Capsule 10's

Pain relief (1348)Rx required

Key Information

Generic Name

Generic Name Celecoxib 100 mg

Manufacturer

Pfizer Ltd

Variant

10 Capsule(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT CELEBREX 100MG CAPSULECELEBREX 100MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs.CELEBREX 100MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps). CELEBREX 100MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above). CELEBREX 100MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease). The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency). Before taking CELEBREX 100MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood). CELEBREX 100MG CAPSULE is not recommended for use in pregnant and breast-feeding women. CELEBREX 100MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor. The most common

Uses

OF CELEBREX 100MG CAPSULE Manage osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, primary dysmenorrhea and familial adenomatous polyposis in adults Manage juvenile rheumatoid arthritis in children (aged 2 years and above)

How It Works

CELEBREX 100MG CAPSULE works by blocking the release of COX-2 enzyme (responsible for pain and inflammation) which provides relief from the pain and inflammation due to arthritis and primary dysmenorrhea in affected individuals.

Directions for Use

Capsule: Take CELEBREX 100MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Mouth Dissolving Tablet: Place CELEBREX 100MG CAPSULE in

Side Effects

taking CELEBREX 100MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen. USES OF CELEBREX 100MG CAPSULE Manage osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, primary dysmenorrhea and familial adenomatous polyposis in adults Manage juvenile rheumatoid arthritis in children (aged 2 years and above) HOW CELEBREX 100MG CAPSULE WORKSCELEBREX 100MG CAPSULE works by blocking the release of COX-2 enzyme (responsible for pain and inflammation) which provides relief from the pain and inflammation due to arthritis and primary dysmenorrhea in affected individuals. DIRECTIONS FOR USECapsule: Take CELEBREX 100MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Mouth Dissolving Tablet: Place CELEBREX 100MG CAPSULE inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF CELEBREX 100MG CAPSULECOMMON high blood pressure (including worsening of existing high blood pressure) fluid buildup with swollen ankles, legs and/or hands urinary infections shortness of breath sinus inflammation/infection blocked/painful sinuses blocked/runny nose, sore throat, cough cold upper respiratory infection or flu like symptoms such as runny nose, sore throat and cough dizziness, headache difficulty sleeping stomach-ache, indigestion, nausea, vomiting, diarrhea, wind rash, itching muscle stiffness difficulty swallowing painful joints worsening of existing allergies accidental injury UNCOMMON stroke heart failure pounding heartbeat fast heart rate anemia drowsiness, anxiety, depression, tiredness, tingling sensations signs of hyperkalemia (high potassium level in blood) such as nausea, fatigue, muscle weakness impaired/blurred vision ringing in the ears mouth pain and sores difficulty hearing constipation, burping, signs of stomach inflammation such as indigestion, stomach-ache or vomiting worsening of inflammation of the stomach/intestine leg cramps raised itchy rash eye inflammation difficulty breathing skin discoloration generalized chest pain not related to heart face swelling diverticulitis (inflammation/infection of one/more small pouches of digestive tract) inflammation of esophagus (tube connecting the mouth to stomach) gastroenteritis (inflammation and infection of digestive system) gastroesophageal reflux (digestive disease that irritates food pipe lining) piles hiatal hernia dark stools tenesmus (feeling to pass stools) heart disorder signs of hypersensitivity/allergic reaction such as difficulty swallowing/breathing, wheezing, fear/anxiety tiredness fever hot flushes peripheral pain (disorder of peripheral nerves) leg cramps, hypertonia (muscle overactivity) spinning sensation deafness joint pain muscle pain inflamed joint inflammation/irritation of joint nose bleeding thrombocythemia (blood disorder) eating disorder depression increase in appetite nervousness bronchitis (inflammation of bronchial tube that carry air to lungs) wheezing RARE ulcers (bleeding) in the stomach, gullet or intestines signs of intestine rupture such as can cause stomach ache, fever, nausea, vomiting, intestinal blockage dark or black stools inflammation of the pancreas (that can lead to stomach pain) inflammation of the gullet (esophagus) signs of hyponatremia (low sodium level in blood) such as nausea and vomiting, headache, confusion signs of reduced number of white blood cells such as repeated fevers and infections, bladder infections, mouth sores signs of reduced number of platelets such as easy or excessive bruising, superficial bleeding, prolonged bleeding from cuts difficulty coordinating muscular movements feeling confused abnormal taste increased sensitivity to light loss of hair hallucinations bleeding in the eye acute reaction which may cause lung inflammation flushing signs of blood clot in lung such as sudden breathlessness, sharp pains when you breathe or collapse inflammation of the intestine or colon, signs of bleeding of the stomach or intestine such as bloody stools or vomiting signs liver inflammation (hepatitis) such as nausea, diarrhea, jaundice (yellow discolouration of the skin or eyes), dark urine, pale stools, bleeding easily, itching or chills acute kidney failure menstrual disturbances swelling of the lips, mouth, tongue or throat or difficulty swallowing Stop taking CELEBREX 100MG CAPSULE and contact your doctor immediately if you experience any of the signs of a severe allergic events such as: signs of an allergic or hypersensitivity reaction such as skin rash, swelling of the face, wheezing or difficulty breathing heart problems such as pain in the chest signs of severe stomach pain/any signs of bleeding in the stomach or intestines such as passing black/bloodstained stools or vomiting blood skin reaction such as rash, blistering or peeling of the skin signs of liver failure/hepatoxicity such as nausea, diarrhea, jaundice (yellow discolouration of the skin or eyes), tiredness signs of exfoliative dermatitis with symptoms such as severe inflammation of the entire skin surface signs of stevens-johnson syndrome with symptoms such as serious disorder of the skin and mucous membranes signs of toxic epidermal necrolysis with symptoms such as blistering and peeling of the skin signs of erythema multiforme with symptoms such as skin reaction that can be triggered by an infection signs of drug reaction with systemic symptoms and eosinophilia signs of acute generalized exanthematous pustulosis with symptoms of red skin studded with pinhead-sized bumps with white pus

Warnings & Precautions

& PRECAUTIONSPREGNANCYCELEBREX 100MG CAPSULE is not recommended for use during pregnancy and in women planning for pregnancy. Consult your doctor before taking the medicine. BREASTFEEDINGCELEBREX 100MG CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESDo not take drive or operate machines if you feel dizzy or drowsy after taking CELEBREX 100MG CAPSULE. ALCOHOLAvoid consumption of alcohol while taking CELEBREX 100MG CAPSULE since it might increase the risk of getting a stomach ulcer/intestinal bleeding. KIDNEYCELEBREX 100MG CAPSULE is not recommended in patients with kidney disease such as severe renal insufficiency. It should be used with caution in patients with kidney disease. Consult your doctor before taking the medicine. LIVERCELEBREX 100MG CAPSULE is not recommended for use in patients with liver disease such as severe hepatic impairment. It should be used with caution in patients with elevated liver enzymes, hepatotoxicity, moderate hepatic impairment. Consult your doctor before taking. ALLERGYDo not take CELEBREX 100MG CAPSULE if you are allergic to Celecoxib, sulfonamides, aspirin, other NSAIDs and/or any of the other ingredients of this medicine. LUNGSCELEBREX 100MG CAPSULE is not recommended for use in patients with asthma. Consult your doctor before taking the medicine. HEART DISEASECELEBREX 100MG CAPSULE is not recommended for use in patients with heart problems such as heart failure, ischemic heart disease, recent heart attack, heart block, perioperative period in the setting of coronary artery bypass graft surgery. It should be used with caution in patients with cardiovascular (CV) thrombotic events, myocardial infarction, stroke and congestive heart failure. Consult your doctor before taking. OTHERSCELEBREX 100MG CAPSULE is not recommended for use if you: have/had an ulcer in stomach/intestines have/had suffered from bleeding in stomach/intestines suffer from an inflammatory disease of the intestines such as ulcerative colitis/Crohn’s disease had problems with your blood circulation such as peripheral arterial disease had surgery on the arteries of your legs have urticaria (red itchy skin) Before taking CELEBREX 100MG CAPSULE, inform your doctor if you: new onset or worsening of hypertension have diabetes have raised blood pressure have increased cholesterol are taking antiplatelet therapies have signs of fluid retention such as swollen ankles and feet are dehydrated due to sickness or diarrhea are a smoker have serious allergic reaction or a serious skin reaction to any medicines feel ill due to an infection or think you have an infection have hyperkalemia (increased potassium level in blood) signs of anaphylaxis (life threatening allergic reaction) such as lightheadedness, faint, breathing difficulties, wheezing disseminated intravascular coagulation (serious blood disorder) are suffering from skin reactions such as exfoliative dermatitis, stevens-johnson syndrome and toxic epidermal necrolysis have lactose intolerance Use in Pediatrics: CELEBREX 100MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) only to manage juvenile rheumatoid arthritis. It is not recommended to manage other conditions in children except juvenile rheumatoid arthritis. Consult your doctor before taking the medicine. Use in Geriatrics: CELEBREX 100MG CAPSULE should be used with caution in elderly patients (aged above 65-years.) Consult your doctor before taking the medicine.

Drug Interactions

SA. Drug - Drug interactions: Before taking CELEBREX 100MG CAPSULE, inform your doctor if you are taking, dextromethorphan (used to manage coughs) fluconazole, rifampicin, ketoconazole (used to manage fungal infections) warfarin (used to manage blood clots) lithium (used to manage depressive disorders) antidepressants (medicines used to manage depression) such as SSRI (Ex. fluoxetine, paroxetine), SNRI (Ex. duloxetine) barbiturates (used to manage epilepsy/seizures, sleep disorders) Ex. phenobarbital medicines used to manage irregular heartbeat (Ex. digoxin, flecainide, amiodarone) neuroleptics (used to manage some mental disorders) Ex. chlorpromazine methotrexate (used to manage rheumatoid arthritis, psoriasis and leukemia) carbamazepine (used to manage epilepsy, pain or depression) ciclosporin and tacrolimus (used for immune system suppression) sulfonamides (used to manage bacterial infections) Ex. sulfadiazine NSAIDS (used to reduce pain, fever or inflammation) Ex. aspirin, ibuprofen, diclofenac glyburide, tolbutamide (medicines used to manage type 2 diabetes) phenytoin (medicine used to manage seizures) corticosteroids (used to provide relief from inflammation) Ex. prednisolone pemetrexed (used to manage metastatic non squamous small lung cancer) medicines used to manage hypertension and other disorders such as ACE inhibitors (Ex. benazepril), angiotensin II antagonists (Ex. azilsartan), beta blockers (Ex. acebutolol), diuretics (Ex. chlorothiazide) Overdosage: If you or anyone else accidentally take too much of CELEBREX 100MG CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include lethargy, drowsiness, nausea, vomiting, epigastric pain (pain/discomfort in upper abdominal region), gastrointestinal bleeding, high blood pressure, acute renal failure, respiratory depression and coma. SYNOPSIS Drug : Celecoxib Pharmacological Category : COX-2 Inhibitor Therapeutic Indication : Osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, in patients 2 years and older, ankylosing spondylitis, acute pain, primary dysmenorrhea, familial adenomatous polyposis Dosage Forms : Capsule, Mouth Dissolving Tablet MORE INFORMATION Keep CELEBREX 100MG CAPSULE out of reach of children Store the medicine below 30°C

Article Information

DW

Written By

DETAILS Written By Dr. K .AZEEM HUSSAIN

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

09 Dec 2022

Tags

#pain relief (1348)#generic name celecoxib 100 mg