Cefrine Plus 1.5gm Injection 1's
Key Information
Generic Name
Generic Name Ceftriaxone 1 gm+Sulbactam 500 mg
Manufacturer
Macleods Pharmaceuticals Pvt Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT CEFRINE PLUS 1.5GM INJECTIONCEFRINE PLUS 1.5GM INJECTION is a combination of Ceftriaxone and Sulbactam, which belongs to the group of medicines called Antibiotics. It is used in the management of infections of the brain (meningitis), lungs, middle ear, abdomen, and abdominal wall (peritonitis), urinary tract and kidneys, bones and joints, skin or soft tissues, blood, and heart. CEFRINE PLUS 1.5GM INJECTION can also be used to manage specific sexually transmitted infections (gonorrhoea and syphilis), patients with low white blood cell counts (neutropenia) who have fever due to bacterial infection, Lyme disease (caused by tick bites), and infections during surgery. CEFRINE PLUS 1.5GM INJECTION is not recommended for use in premature babies and new-born babies having jaundice. Before receiving CEFRINE PLUS 1.5GM INJECTION, inform your doctor if you have liver or kidney diseases, colitis, hemolytic anemia, gallstones or kidney stones, upcoming surgeries, or pancreatitis. CEFRINE PLUS 1.5GM INJECTION should be used with caution in pregnancy and breast feeding. Contact your doctor before receiving. CEFRINE PLUS 1.5GM INJECTION is not recommended for use in premature babies. Contact your child’s doctor. CEFRINE PLUS 1.5GM INJECTION should be used with caution in elderly patients (aged above 65 years or above). Contact your doctor before receiving. The most common
Uses
OF CEFRINE PLUS 1.5GM INJECTIONManage bacterial infections involving: Brain (meningitis) Lungs Middle ear Abdomen and abdominal wall (peritonitis) Urinary tract and kidneys Bones and joints Skin or soft tissues Blood Heart Sexually transmitted infections (gonorrhoea and syphilis) Low white blood cell counts (neutropenia) Lyme disease (caused by tick bites) Infections during surgery
How It Works
CEFRINE PLUS 1.5GM INJECTION helps to manage infections, where Ceftriaxone is a cephalosporin antibiotic that works by inhibiting the synthesis of bacterial cell walls, leading to destruction of the bacteria, and Sulbactam is a beta-lactamase inhibitor that works by binding and inhibiting beta-lactamase (an enzyme that destroys antibiotic activity) produced by bacterial cells and thereby manages the reduction in antibacterial activity.
Directions for Use
CEFRINE PLUS 1.5GM INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or infusion or into a muscle as an intramuscular injection. Your doctor will decide the correct dose and duration of CEFRINE PLUS 1.5GM INJECTION for you depending upon your age, body weight, and severity of the disease condition.
Side Effects
receiving CEFRINE PLUS 1.5GM INJECTION are diarrhea, rash, itching, pain at the site of injection, and inflammation of a vein caused by blood clots. Contact your doctor if any of the symptoms worsen. USES OF CEFRINE PLUS 1.5GM INJECTIONManage bacterial infections involving: Brain (meningitis) Lungs Middle ear Abdomen and abdominal wall (peritonitis) Urinary tract and kidneys Bones and joints Skin or soft tissues Blood Heart Sexually transmitted infections (gonorrhoea and syphilis) Low white blood cell counts (neutropenia) Lyme disease (caused by tick bites) Infections during surgery HOW CEFRINE PLUS 1.5GM INJECTION WORKSCEFRINE PLUS 1.5GM INJECTION helps to manage infections, where Ceftriaxone is a cephalosporin antibiotic that works by inhibiting the synthesis of bacterial cell walls, leading to destruction of the bacteria, and Sulbactam is a beta-lactamase inhibitor that works by binding and inhibiting beta-lactamase (an enzyme that destroys antibiotic activity) produced by bacterial cells and thereby manages the reduction in antibacterial activity. DIRECTIONS FOR USECEFRINE PLUS 1.5GM INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or infusion or into a muscle as an intramuscular injection. Your doctor will decide the correct dose and duration of CEFRINE PLUS 1.5GM INJECTION for you depending upon your age, body weight, and severity of the disease condition. SIDE EFFECTS OF CEFRINE PLUS 1.5GM INJECTIONCOMMON Pain, tenderness, warmth, and tightness at the injection site Rash Low count of the blood cells Diarrhoea Changes in liver function tests characterized by abdominal pain, yellowing of skin or eyes, dark urine, pale stools UNCOMMON Inflammation of the vein Itching Fever, chills Genital fungal infections Nausea, vomiting Changes in taste Headache Dizziness RAREStop receiving CEFRINE PLUS 1.5GM INJECTION and contact your doctor immediately if you experience any of the following side effects: Allergic reactions such as rash, red skin, blistering of lips, eyes, and mouth, skin peeling, high fever, flu-like symptoms, increased levels of liver enzymes, and an increase in eosinophils and enlarged lymph nodes Sudden swelling of the throat or face causing difficulty in breathing or swallowing; sudden swelling of the hands, feet, and ankles
Warnings & Precautions
& PRECAUTIONSPREGNANCYUse with CautionCEFRINE PLUS 1.5GM INJECTION should be used with caution in pregnant women. Consult your doctor before receiving CEFRINE PLUS 1.5GM INJECTION. BREASTFEEDINGUse with CautionCEFRINE PLUS 1.5GM INJECTION should be used with caution in breastfeeding women. Consult your doctor before receiving. DRIVING AND USING MACHINESContraindicatedDo not drive or operate any machines if you feel dizziness after receiving CEFRINE PLUS 1.5GM INJECTION. KIDNEYUse with CautionCEFRINE PLUS 1.5GM INJECTION should be used with caution in patients with kidney disease such as kidney stones. Consult your doctor before receiving CEFRINE PLUS 1.5GM INJECTION. LIVERUse with CautionCEFRINE PLUS 1.5GM INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving. ALLERGYContraindicatedDo not receive CEFRINE PLUS 1.5GM INJECTION if you are allergic to ceftriaxone, sulbactam, penicillin, or similar antibiotics like carbapenems, monobactams, lidocaine, or any of the other ingredients of this medicine. USE IN PEDIATRICSContraindicatedCEFRINE PLUS 1.5GM INJECTION is not recommended for use in premature babies and new-born babies with jaundice. Ask for the advice of your child’s doctor. USE IN GERIATRICSUse with CautionCEFRINE PLUS 1.5GM INJECTION should be used with caution in elderly patients (aged 65 years or above). Your doctor might consider lowering your doses depending upon your health condition. Contact your doctor before receiving CEFRINE PLUS 1.5GM INJECTION. OTHERSTell your physician before receiving CEFRINE PLUS 1.5GM INJECTION if you have or had: Gut problems like colitis (inflammation of the bowel) Pancreatitis Haemolytic anaemia Low sodium diet Upcoming surgeries Gall bladder stones Blood tests (coombs test) or urine test (for glucose)
Drug Interactions
SA. Drug-Drug Interactions: Before receiving CEFRINE PLUS 1.5GM INJECTION, inform your doctor if you are taking any of the following medicines: Medicine used to manage blood cancer (Ex. amacrine) Medicines used to manage certain infections (Ex. vancomycin, chloramphenicol, tobramycin, gentamycin) Medicine used to manage fungal infections (Ex. fluconazole) Medicines used to manage pregnancy, oral contraceptives (Ex. ethinyl estradiol, levonorgestrel) Medicines used to manage blood clots (Ex. dabigatran, rivaroxaban) Medicines used to manage gout (Ex. probenecid) Calcium-containing diluents (such as Ringers’ solution and Hartman’s solution) Overdosage: CEFRINE PLUS 1.5GM INJECTION will be administered only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if there are any unusual symptoms. SYNOPSIS Drug : Ceftriaxone and Sulbactam Pharmacological Category : Cephalosporin Antibiotics and Beta-lactamase inhibitors Therapeutic Indication : Manages Bacterial infections Dosage Forms : Injection MORE INFORMATIONSTORAGE Keep CEFRINE PLUS 1.5GM INJECTION out of reach of children Store CEFRINE PLUS 1.5GM INJECTION below 30°C
Frequently Asked Questions
Common questions and answers about Cefrine Plus 1.5gm Injection 1's.
How CEFRINE PLUS 1.5GM INJECTION is given?
CEFRINE PLUS 1.5GM INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or infusion or into a muscle as an intramuscular injection. Your doctor will decide the correct dose and duration of CEFRINE PLUS 1.5GM INJECTION for you depending upon your age, body weight, and severity of the disease condition.
Can CEFRINE PLUS 1.5GM INJECTION cause diarrhea?
Yes. CEFRINE PLUS 1.5GM INJECTION cause diarrhea. Drink lots of fluids, such as water or fruit juices, to keep you hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if the symptom does not improve.
Can I stop receiving CEFRINE PLUS 1.5GM INJECTION on my own?
Do not stop receiving CEFRINE PLUS 1.5GM INJECTION unless your doctor tells you to. Stopping early may not prove the medicine to be properly effective. If you have any further questions on the use of CEFRINE PLUS 1.5GM INJECTION, ask your doctor.
Who should avoid receiving CEFRINE PLUS 1.5GM INJECTION?
CEFRINE PLUS 1.5GM INJECTION is not recommended for premature babies and new-borns with jaundice, or if you are allergic to ceftriaxone, sulbactam, penicillin, or similar antibiotics like carbapenems, monobactams, lidocaine, or any of the other ingredients of this medicine. Contact your doctor before receiving CEFRINE PLUS 1.5GM INJECTION.
Does CEFRINE PLUS 1.5GM INJECTION cause kidney stones? Yes. CEFRINE PLUS 1.5GM INJECTION might cause kidney stones. Also, CEFRINE PLUS 1.5GM INJECTION should be used with caution in patients with kidney stones. Consult your doctor before receiving.
Q: Does CEFRINE PLUS 1.5GM INJECTION cause kidney stones? Yes. CEFRINE PLUS 1.5GM INJECTION might cause kidney stones. Also, CEFRINE PLUS 1.5GM INJECTION should be used with caution in patients with kidney stones. Consult your doctor before receiving.
What is CEFRINE PLUS 1.5GM INJECTION used for?
CEFRINE PLUS 1.5GM INJECTION is used in the management of infections of the brain (meningitis), lungs, middle ear, abdomen and abdominal wall (peritonitis), urinary tract and kidneys, bones and joints, skin or soft tissues, blood, and heart. It can also be used to manage specific sexually transmitted infections (gonorrhoea and syphilis), patients with low white blood cell counts (neutropenia) who have fever due to bacterial infection, Lyme disease (caused by tick bites), and infections during surgery.
Is CEFRINE PLUS 1.5GM INJECTION safe during pregnancy?
CEFRINE PLUS 1.5GM INJECTION should be used with caution in pregnant women. Consult your doctor before receiving CEFRINE PLUS 1.5GM INJECTION.
Can CEFRINE PLUS 1.5GM INJECTION be used in children?
CEFRINE PLUS 1.5GM INJECTION is not recommended for use in premature babies and new-born babies with jaundice. Ask for the advice of your child’s doctor.
What are the side effects of using CEFRINE PLUS 1.5GM INJECTION?
The most common side effects of receiving CEFRINE PLUS 1.5GM INJECTION are diarrhea, rash, itching, pain at the site of injection, and inflammation of a vein caused by blood clots. Contact your doctor if any of the symptoms worsen.
What precautions must be taken while using CEFRINE PLUS 1.5GM INJECTION?
Before receiving CEFRINE PLUS 1.5GM INJECTION, inform your doctor if you have or had kidney disease such as kidney stones, liver disease, gut problems like colitis (inflammation of the bowel), pancreatitis, hemolytic anemia, low sodium diet, upcoming surgeries, gall bladder stones, or are scheduled for blood tests (coombs test) or urine tests (for glucose).
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
26 Jul 2024