Cefokem XP 1gm Injection 1's
Key Information
Generic Name
Generic Name Cefoperazone 1 gm+Sulbactam 500 mg
Manufacturer
Alkem Laboratories Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT CEFOKEM XP 1GM INJECTIONCEFOKEM XP 1GM INJECTION is a combination of Cefoperazone and Sulbactam, which belongs to the group of medicines called Antibiotics. It is used to manage various bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia (serious bloodstream infection), meningitis (inflammation of brain and spinal cord membranes, typically caused by an infection), and skin and soft tissue infections. It is also used to manage bone and joint infections, gonorrhoea (sexually transmitted bacterial infection), endometritis (inflammation of the uterine lining due to infection), pelvic inflammatory disease (infection of the female reproductive organs), and other infections of the genital tract. Bacterial infections are caused by the multiplication of specific harmful strains of bacteria anywhere in the body. It is characterized by symptoms such as fever, nausea, vomiting, headache, tiredness, and swollen lymph nodes in the neck, armpits, groin, or elsewhere. Before receiving CEFOKEM XP 1GM INJECTION, inform your doctor if you have impaired kidney function, severe biliary obstruction (blockage of the bile ducts), severe liver disease, or malabsorption conditions, and have a schedule for laboratory tests (such as measuring glucose in the urine). CEFOKEM XP 1GM INJECTION should be used with caution in pregnant and breastfeeding women only if advised by the doctor. Also, it should be used with caution in children and elderly patients. The most common
Uses
OF CEFOKEM XP 1GM INJECTIONManages bacterial infections such as: Respiratory tract infections Urinary tract infections (upper and lower) Intra-abdominal infections Septicaemia Meningitis Skin and soft tissue infections Bone and joint infections Pelvic inflammatory disease Endometritis Gonorrhoea Other infections of the genital tract
How It Works
CEFOKEM XP 1GM INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections.
Directions for Use
CEFOKEM XP 1GM INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection.
Side Effects
receiving CEFOKEM XP 1GM INJECTION are diarrhea, nausea, and vomiting. Inform your doctor if any of these side effects bother you. USES OF CEFOKEM XP 1GM INJECTIONManages bacterial infections such as: Respiratory tract infections Urinary tract infections (upper and lower) Intra-abdominal infections Septicaemia Meningitis Skin and soft tissue infections Bone and joint infections Pelvic inflammatory disease Endometritis Gonorrhoea Other infections of the genital tract HOW CEFOKEM XP 1GM INJECTION WORKSCEFOKEM XP 1GM INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections. DIRECTIONS FOR USECEFOKEM XP 1GM INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection. SIDE EFFECTS OF CEFOKEM XP 1GM INJECTIONCOMMON Diarrhea Nausea, vomiting Coagulopathy (impairment in the blood's ability to clot) UNCOMMON Headache Itching Raised red rashes (urticaria) Pain or inflammation of a vein at the site of injection Fever, chills RAREInform your doctor immediately if you experience any of the following side effects after receiving CEFOKEM XP 1GM INJECTION: Allergic reactions Skin reactions such as toxic epidermal necrolysis, Stevens-Johnson syndrome, and dermatitis exfoliative (signs include blistering and peeling of the skin). Persistent bleeding
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredCEFOKEM XP 1GM INJECTION should be used during pregnancy only if considered clearly necessary. Consult your doctor before receiving CEFOKEM XP 1GM INJECTION. BREASTFEEDINGUse with CautionCEFOKEM XP 1GM INJECTION should be used with caution in breast-feeding women, as a small amount of this medicine is excreted in the breast milk. Consult your doctor before receiving CEFOKEM XP 1GM INJECTION. DRIVING AND USING MACHINESSafeCEFOKEM XP 1GM INJECTION does not affect your ability to drive or use machinery. ALCOHOLContraindicatedAvoid consuming alcohol while receiving CEFOKEM XP 1GM INJECTION because it may cause flushing, sweating, headaches, and an increase in the heartbeat. KIDNEYUse with CautionCEFOKEM XP 1GM INJECTION should be used with caution in patients with impaired kidney function. Consult your doctor before receiving CEFOKEM XP 1GM INJECTION. LIVERUse with CautionCEFOKEM XP 1GM INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor before receiving CEFOKEM XP 1GM INJECTION. ALLERGYContraindicatedDo not receive CEFOKEM XP 1GM INJECTION if you are allergic to cefoperazone, sulbactam, beta-lactam antibiotics (such as Penicillins and cephalosporins (Ex. cefuroxime)) or any other ingredients of this medicine. USE IN PEDIATRICSUse with CautionCEFOKEM XP 1GM INJECTION should be used with caution in children. Your child’s doctor may adjust the dose depending upon the child's body weight. Consult your child’s doctor for advice. USE IN GERIATRICSUse with CautionCEFOKEM XP 1GM INJECTION should be used with caution in elderly patients. Consult your doctor before receiving it. OTHERSBefore receiving CEFOKEM XP 1GM INJECTION, inform your doctor if you: Have poor diet and malabsorption conditions Have any scheduled laboratory tests (such as measuring glucose in the urine)
Drug Interactions
SA. Drug-Drug interactions: Before receiving CEFOKEM XP 1GM INJECTION, inform your doctor if you are taking any of the following medicines: Medicines used to manage bacterial infections, such as aminoglycosides (Ex. gentamicin, tobramycin, amikacin, and streptomycin) Oral anti-coagulants (Ex. warfarin) (used to manage or manage blood clots) Overdosage: CEFOKEM XP 1GM INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms, such as neurologic effects (such as fits). SYNOPSIS Drug : Cefoperazone, Sulbactam Pharmacological Category : Cephalosporin; Beta-lactamase inhibitors Therapeutic Indication : Various bacterial infections Dosage Forms : Injection MORE INFORMATIONSTORAGE Store below 25°C and protect from light
Frequently Asked Questions
Common questions and answers about Cefokem XP 1gm Injection 1's.
What is CEFOKEM XP 1GM INJECTION used for?
CEFOKEM XP 1GM INJECTION is a combination of Cefoperazone and Sulbactam, which belongs to the group of medicines called antibiotics. It is used to manage several bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia, meningitis, skin and soft tissue infections, bone and joint infections, gonorrhoea, endometritis, pelvic inflammatory disease, and other infections of the genital tract.
How does CEFOKEM XP 1GM INJECTION work?
CEFOKEM XP 1GM INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections.
Is CEFOKEM XP 1GM INJECTION safe for kidneys?
CEFOKEM XP 1GM INJECTION should be used with caution in patients with impaired kidney function. Consult your doctor before receiving CEFOKEM XP 1GM INJECTION.
How CEFOKEM XP 1GM INJECTION is administered?
CEFOKEM XP 1GM INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection.
Is CEFOKEM XP 1GM INJECTION safe to use in patients with liver disease?
CEFOKEM XP 1GM INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor for advice before receiving CEFOKEM XP 1GM INJECTION.
What are the side effects of CEFOKEM XP 1GM INJECTION?
The most common side effects of receiving CEFOKEM XP 1GM INJECTION are diarrhea, nausea, vomiting, and coagulopathy (impairment in the blood's ability to clot). Inform your doctor if any of these side effects bother you.
Is CEFOKEM XP 1GM INJECTION safe during pregnancy?
CEFOKEM XP 1GM INJECTION should be used during pregnancy only if considered clearly necessary. Consult your doctor before receiving CEFOKEM XP 1GM INJECTION.
Can CEFOKEM XP 1GM INJECTION be used in children?
CEFOKEM XP 1GM INJECTION should be used with caution in children. Your child’s doctor may adjust the dose depending upon the child's body weight. Consult your child’s doctor for advice.
Who should not use CEFOKEM XP 1GM INJECTION?
Do not receive CEFOKEM XP 1GM INJECTION if you are allergic to cefoperazone, sulbactam, beta-lactam antibiotics (such as Penicillins and cephalosporins (Ex. cefuroxime)) or any other ingredients of this medicine.
What precautions must be taken while using CEFOKEM XP 1GM INJECTION?
Before receiving CEFOKEM XP 1GM INJECTION, inform your doctor if you have impaired kidney function, severe biliary obstruction (blockage of the bile ducts), severe liver disease, poor diet and malabsorption conditions, or have any scheduled laboratory tests (such as measuring glucose in the urine).
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
26 Jul 2024