CAPESTATIC 500 Tablet 10's
Key Information
Generic Name
Generic Name Capecitabine 500 mg
Manufacturer
PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED (Generics)
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
CAPESTATIC 500 TABLET contains capecitabine, which belongs to the group of medicines called antineoplastic agents. It is used in the management of abnormal growth of cells present in the colon, rectal, gastric, and breast regions. It may be used either alone or in combination with other medicines. CAPESTATIC 500 TABLET is not recommended for use if you have severe liver or kidney disease. CAPESTATIC 500 TABLET should be used with caution in patients with liver disease, kidney disease, heart problems, brain disease or nerve damage, diabetes, or a history of eye problems. Consult your doctor before taking this medicine. CAPESTATIC 500 TABLET is not recommended for use by pregnant or breastfeeding women. Consult your doctor before taking this medicine. CAPESTATIC 500 TABLET is not recommended for use by children and adolescents. Consult your doctor before taking this medicine. The most common
Uses
OF CAPESTATIC 500 TABLET It inhibits the abnormal growth of cells present in the colon, rectal, gastric, and breast regions.
How It Works
CAPESTATIC 500 TABLET is an antimetabolite that works by stopping the abnormal growth of cells. Thus, it helps manage the conditions associated with it.
Directions for Use
Take CAPESTATIC 500 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Take the medicine within 30 minutes after the end of a meal. Your doctor will decide the correct dose and duration of CAPESTATIC 500 TABLET for you depending upon your age, body surface area, and disease condition. Do not stop taking CAPESTATIC 500 TABLET unless your doctor has told you to.
Side Effects
taking CAPESTATIC 500 TABLET are abdominal pain, rash, dry or itchy skin, tiredness, and loss of appetite. Consult your doctor if any of these symptoms worsen. USES OF CAPESTATIC 500 TABLET It inhibits the abnormal growth of cells present in the colon, rectal, gastric, and breast regions. HOW CAPESTATIC 500 TABLET WORKSCAPESTATIC 500 TABLET is an antimetabolite that works by stopping the abnormal growth of cells. Thus, it helps manage the conditions associated with it. DIRECTIONS FOR USETake CAPESTATIC 500 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Take the medicine within 30 minutes after the end of a meal. Your doctor will decide the correct dose and duration of CAPESTATIC 500 TABLET for you depending upon your age, body surface area, and disease condition. Do not stop taking CAPESTATIC 500 TABLET unless your doctor has told you to. SIDE EFFECTS OF CAPESTATIC 500 TABLETCOMMON Abdominal pain Rash, dry, or itchy skin Tiredness Loss of appetite Dehydration and weight loss Sleeplessness (insomnia), depression Headache, sleepiness, and dizziness Tingling sensations or numbness in the skin Changes in taste Increased tears, irritation in the eye, and redness of the eyes (conjunctivitis) Inflammation of the veins (thrombophlebitis) Shortness of breath, bleeding from the nose, cough, or runny nose Cold sores or other herpes infections Infections of the lungs or respiratory system (pneumonia or bronchitis) Bleeding from the gut, constipation, pain in the upper abdomen, indigestion, excess wind Dry mouth Skin problems (rash, reddening, dry skin, itching, skin discoloration, skin loss) Inflammation, nail disorder, hair loss (alopecia) Painful joints or limbs (hands and legs), chest, or back Fever, swelling in the limbs, feeling ill Nerve pain Ringing or buzzing in the ears (tinnitus), loss of hearing Hiccups, change in voice Pain or altered or abnormal sensation in the mouth; pain in the jaw; sweating; night sweats Muscle spasm Difficulty in urinating, blood, or protein in the urine Bruising or reaction at the injection site UNCOMMON Blood infection, urinary tract infection, infection of the skin, infections in the nose and throat, fungal infections (including those of the mouth), influenza, gastroenteritis, tooth abscess Lumps under the skin (lipoma) Allergy Diabetes Malnutrition Confusional state, panic attacks, and a depressed mood Decreased libido Difficulty speaking Impaired memory Loss of movement coordination, balance problems Fainting Nerve damage and altered sensation Blurred or double vision Vertigo, pain in the ear Irregular and fast heartbeat (arrhythmias), chest pain, and heart attack Blood clots in the deep veins High or low blood pressure Hot flushes Cold limbs (hands or feet) Purple spots on the skin Respiratory problems such as blood clots in the veins in the lung (pulmonary embolism), collapsed lungs, coughing up blood, asthma, and shortness of breath on exertion Gastrointestinal problems (bowel obstruction, collection of fluid in the abdomen, inflammation of the small or large intestine, the stomach, or the oesophagus, pain in the lower abdomen, abdominal discomfort, heartburn, blood in the stool) Jaundice (yellowing of the skin and eyes) Ulcer and blister on skin, skin reaction with sunlight, reddening of palms, swelling or pain of the face Joint swelling or stiffness of joints, bone pain, weakness, or stiffness of muscles Fluid collection in the kidneys, an increase in the frequency of urination during the night, and incontinence (loss of bladder control) Unusual bleeding from the vagina Swelling (oedema) Chills and rigors RARE Narrowing or blockage of the tear duct (lacrimal duct stenosis) Liver failure, inflammation leading to dysfunction or obstruction in bile secretion (cholestatic hepatitis) Specific changes in the electrocardiogram (QT prolongation) Certain types of arrhythmias (including ventricular fibrillation, torsade de pointes, and bradycardia) Eye inflammation causing eye pain and possibly eyesight problems Inflammation of the skin causing red, scaly patches due to an immune system illness Stop taking CAPESTATIC 500 TABLET and contact your doctor immediately if you experience any of the following side effects: Diarrhoea Nausea and vomiting Stomatitis (redness, pain, swelling, or sores in the mouth or throat) Hand-and-foot skin reaction (pain, swelling, redness, or tingling of hands and/or feet) Fever Infection Chest pain Steven Johnson syndrome (painful red or purplish rash that spreads and blisters or other lesions begin to appear in the mouth and lips), especially if you had before light sensitivity, infections of the respiratory system (Ex. bronchitis), and/or fever Angioedema (swelling of the lips, face, throat, or tongue causing difficulty swallowing or breathing, itchiness, and rashes)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedCAPESTATIC 500 TABLET is not recommended for use by pregnant women. Women of childbearing potential should use effective contraception during management with CAPESTATIC 500 TABLET and for 6 months after the last dose. If you are a male patient and your female partner could become pregnant, you should use effective contraception during management with CAPESTATIC 500 TABLET and for 3 months after the last dose. Consult your doctor before taking CAPESTATIC 500 TABLET. BREASTFEEDINGContraindicatedCAPESTATIC 500 TABLET is not recommended for use in breastfeeding women, and do not breastfeed for 2 weeks after the last dose of CAPESTATIC 500 TABLET. Consult your doctor before taking it. DRIVING AND USING MACHINESContraindicatedDo not drive or operate any machines if you feel dizzy, nauseous, or tired after taking CAPESTATIC 500 TABLET. KIDNEYConsult your doctorCAPESTATIC 500 TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking it. CAPESTATIC 500 TABLET should be used with caution in patients with kidney disease. Consult your doctor before taking CAPESTATIC 500 TABLET. LIVERConsult your doctorCAPESTATIC 500 TABLET is not recommended for use in patients with severe liver disease. Consult your doctor before taking it. CAPESTATIC 500 TABLET should be used with caution in patients with liver disease. Consult your doctor before taking it. ALLERGYContraindicatedDo not take CAPESTATIC 500 TABLET if you are allergic to Capecitabine or any of the other ingredients in this medicine. HEART DISEASEUse with CautionCAPESTATIC 500 TABLET should be used with caution in patients with heart problems (Ex. an irregular heartbeat or chest pain radiating to the jaw and back brought on by physical effort and due to problems with the blood flow to the heart). Consult your doctor before taking CAPESTATIC 500 TABLET. USE IN PEDIATRICSContraindicatedCAPESTATIC 500 TABLET is not recommended for use in children and adolescents. Consult your doctor before taking CAPESTATIC 500 TABLET. OTHERSCAPESTATIC 500 TABLET is not recommended for use if you: Previously had severe reactions to fluoropyrimidine therapy (a group of anticancer medicines such as fluorouracil) Have severely low levels of white cells or platelets in the blood (leukopenia, neutropenia, or thrombocytopenia) Have complete DPD deficiency (do not have any activity of the enzyme dihydropyrimidine dehydrogenase (DPD) Are being managed now or have been managed in the last 4 weeks for herpes zoster (chickenpox or shingles) with brivudine Before taking CAPESTATIC 500 TABLET, inform your doctor if you: Have a partial deficiency in the activity of the enzyme dihydropyrimidine dehydrogenase (DPD) Have a family member who has a partial or complete deficiency of the enzyme dihydropyrimidine dehydrogenase (DPD) Have a brain disease (Ex. cancer that has spread to the brain) or nerve damage (neuropathy) Have a calcium imbalance or other electrolyte imbalances Have diabetes Cannot keep food or water in your body because of severe nausea and vomiting Have a history of eye problems Have diarrhea Are dehydrated Have a severe skin reaction Have intolerance to lactose or other sugars
Drug Interactions
SA. Drug-Drug Interactions: Medicine used in the management of shingles and chickenpox (Ex. brivudine) Medicines used in the management of gout (Ex. allopurinol) Blood-thinning medicines Ex. coumarin, warfarin (medicines used to manage blood clots) Medicines used in the management of seizures or tremors (Ex. phenytoin) Interferon alpha (used in the management of hepatitis B, C, lymphoma, and other cancers) Radiotherapy and certain medicines used to manage cancer (Ex. folinic acid, oxaliplatin, bevacizumab, cisplatin, irinotecan, and fluorouracil) Medicines used to manage folic acid deficiency (Ex. levomefolic acid) Overdosage: If you or anyone else accidentally takes too much of CAPESTATIC 500 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, diarrhea, inflammation or ulceration of the gut or mouth, pain or bleeding from the intestine or stomach, or bone marrow depression (reduction in certain kinds of blood cells). SYNOPSIS Drug : Capecitabine Pharmacological Category : Nucleoside metabolic inhibitor Therapeutic Indication : Inhibits the abnormal growth of cells present in the colon, rectal, gastric, and breast regions Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep CAPESTATIC 500 TABLET out of reach of children Store below 30°C
Frequently Asked Questions
Common questions and answers about CAPESTATIC 500 Tablet 10's.
What should I inform my doctor before starting with CAPESTATIC 500 TABLET?
Before starting the management with CAPESTATIC 500 TABLET, you should inform your doctor if you have kidney, liver, or heart disease, diarrhea, dehydration, nausea and vomiting, brain disease (Ex. cancer that has spread to the brain or nerve damage (neuropathy), diabetes, a history of eye problems, or severe skin reactions.
What if I forget to take a dose of CAPESTATIC 500 TABLET?
If you have missed a dose, take it as soon as you remember it. Do not take a double dose to compensate for the missed dose of CAPESTATIC 500 TABLET. Continue taking the medicine as per your schedule. Talk to your doctor.
Is CAPESTATIC 500 TABLET a form of chemotherapy?
Yes. CAPESTATIC 500 TABLET is an oral chemotherapy medicine that is used in the management of abnormal growth of cells present in the colon, rectal, gastric, and breast regions. Your doctor will decide the correct management plan for you.
How long do I have to take CAPESTATIC 500 TABLET?
Your doctor will decide the correct dose of CAPESTATIC 500 TABLET and number of cycles for you depending upon your body weight, age, and disease condition. CAPESTATIC 500 TABLET are usually taken for 14 days, followed by a 7-day rest period. This 21-day period is one management cycle. In some cases, you will advise taking CAPESTATIC 500 TABLET every day while using it in combination with other medicines.
Can I stop taking CAPESTATIC 500 TABLET if I feel better?
No. You should not stop taking CAPESTATIC 500 TABLET or change the dose until and unless your doctor asks you to. You will be at high risk of getting back the symptoms and dangerous tumour growth. Talk to your doctor.
Can CAPESTATIC 500 TABLET cause eye problems?
Prior to starting management with CAPESTATIC 500 TABLET, you should inform your doctor if you have a history of eye problems. While you are managing with CAPESTATIC 500 TABLET, you may need monitoring of your eyes. Talk to your doctor before taking CAPESTATIC 500 TABLET.
Does CAPESTATIC 500 TABLET shrink tumours?
No, CAPESTATIC 500 TABLET does not shrink tumours. CAPESTATIC 500 TABLET contains capecitabine, which works by stopping or reducing the abnormal growth of cells, which is called cytostatic activity. Only after being absorbed by the body is it changed into an active anti-neoplastic medicine (more in tumour tissue than in normal tissue). Therefore, it stops tumour growth and spreading without causing them to shrink.
Does CAPESTATIC 500 TABLET cause hair loss?
Yes, the most common side effect of CAPESTATIC 500 TABLET is hair loss. Before your management, prepare in advance for changes in your hair. Talk to your doctor about what to expect. Use head coverings such as a wig or scarf. Try to add iron- and protein-rich foods like green leafy vegetables and beans to snacks and meals.
Can I take double doses together to manage my condition soon?
No, do not take more CAPESTATIC 500 TABLET than the normal recommended dose as it may cause overdosage of CAPESTATIC 500 TABLET, leading to harmful side effects such as diarrhea, inflammation of the gut or mouth, pain or bleeding in the stomach or bone marrow, depression (reduction in blood cells), nausea, and vomiting.
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
10 Jul 2024