BRIMAZE T Ophthalmic Solution 10ml
Key Information
Generic Name
Generic Name Brimonidine 0.2 %+Timolol 0.5 %
Manufacturer
Aice Healh Care Pvt Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT BRIMAZE T OPHTHALMIC SOLUTIONBRIMAZE T OPHTHALMIC SOLUTION is a combination of Brimonidine and Timolol which belongs to the group of medicines called an Alpha-adrenergic receptor agonist and Beta-adrenergic receptor inhibitors respectively. BRIMAZE T OPHTHALMIC SOLUTION is used to reduce the elevated intraocular pressure (pressure in
Uses
OF BRIMAZE T OPHTHALMIC SOLUTION Controls glaucoma or intraocular pressure
How It Works
BRIMAZE T OPHTHALMIC SOLUTION helps to lower eye pressure due to glaucoma and intraocular hypertension, where Brimonidine works by allowing better fluid drainage from the eye resulting in reduced pressure in the eye and Timolol works by decreasing the amount of fluid formed in the eye which results in reduced intraocular pressure in the eye thereby managing glaucoma and ocular hypertension.
Directions for Use
Use BRIMAZE T OPHTHALMIC SOLUTION as advised by your physician. It is for ophthalmic use only. Wash your hands before application, tilt your head back slightly and gently pull down the lower eyelid until there is a small pocket. Turn the bottle up
Side Effects
are BRIMAZE T OPHTHALMIC SOLUTION are eye redness, eye burning, stinging or pain in eyes, small breaks on the eye surface, inflammation in the eyelids and itching in eyes. Consult your doctor if any of the side effects worsen. USES OF BRIMAZE T OPHTHALMIC SOLUTION Controls glaucoma or intraocular pressure HOW BRIMAZE T OPHTHALMIC SOLUTION WORKSBRIMAZE T OPHTHALMIC SOLUTION helps to lower eye pressure due to glaucoma and intraocular hypertension, where Brimonidine works by allowing better fluid drainage from the eye resulting in reduced pressure in the eye and Timolol works by decreasing the amount of fluid formed in the eye which results in reduced intraocular pressure in the eye thereby managing glaucoma and ocular hypertension. DIRECTIONS FOR USEUse BRIMAZE T OPHTHALMIC SOLUTION as advised by your physician. It is for ophthalmic use only. Wash your hands before application, tilt your head back slightly and gently pull down the lower eyelid until there is a small pocket. Turn the bottle upside down and squeeze it to release one drop into each eye that needs management. Release the lower lid and close your eye. Keep the eye closed and press your finger against the corner of your eye for two minutes. If you miss a drop, try again. Your doctor will decide the correct dose and duration of BRIMAZE T OPHTHALMIC SOLUTION for you depending upon your age and severity of the condition. SIDE EFFECTS OF BRIMAZE T OPHTHALMIC SOLUTIONCOMMON eye redness or burning stinging or pain in the eye small breaks on the eye surface with or without inflammation swelling, redness or inflammation in the eyelids irritation in the eyes feeling of foreign body in the eye itching of the eye or/and eyelid follicles or white spots on the outer layer covering the surface of the eye disturbance in the vision eye discharge, tearing, dry or sticky eyes allergic conjunctivitis (eye inflammation due to allergy) conjunctival hyperaemia (dilation of blood vessels inside the eye) corneal erosion (eye disorder marked with temporary blindness) headache, general weakness UNCOMMON difficulty in seeing clearly swelling or inflammation of the see-through layer which covers the surface of the eye tired eyes sensitivity to light eyelid pain whitening of the see-through layer which covers the surface of the eyes swelling or areas of inflammation under the surface of the eye floaters in front of the eyes light-headedness, fainting itchy, runny or blocked nose, sneezing dry nose RAREStop using BRIMAZE T OPHTHALMIC SOLUTION and contact your doctor immediately if you experience any of the following side effects: serious allergic reaction with symptoms that include feeling dizzy or faint, rash, itchy skin and swelling of the face, lips, tongue or throat that may cause difficulty breathing or swallowing chest pain or irregular heart rate increased or decreased heart rate or low blood pressure
Warnings & Precautions
& PRECAUTIONSPREGNANCY[GNBKEYWORD] is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before using BRIMAZE T OPHTHALMIC SOLUTION. BREASTFEEDINGBRIMAZE T OPHTHALMIC SOLUTION is not recommended for use in breastfeeding mothers since it may pass into the milk. Consult your doctor before using BRIMAZE T OPHTHALMIC SOLUTION. DRIVING AND USING MACHINESDo not drive or operate machines while using BRIMAZE T OPHTHALMIC SOLUTION as it may cause drowsiness, tiredness or blurred vision. Consult your doctor before using BRIMAZE T OPHTHALMIC SOLUTION. ALCOHOLAvoid or limit consumption of alcohol while using BRIMAZE T OPHTHALMIC SOLUTION. KIDNEYBRIMAZE T OPHTHALMIC SOLUTION should be used with caution in patients with kidney problems. Consult your doctor for advice before using BRIMAZE T OPHTHALMIC SOLUTION. LIVERBRIMAZE T OPHTHALMIC SOLUTION should be used with caution in patient with liver problems. Consult your doctor before using it. ALLERGYBRIMAZE T OPHTHALMIC SOLUTION is not recommended for use if you are allergic to brimonidine, timolol or any other ingredients of this medicine. LUNGSBRIMAZE T OPHTHALMIC SOLUTION is not recommended for use if you have/had respiratory problems such as bronchial asthma, severe chronic obstructive bronchitis (severe lung disease causing noisy breathing, difficulty in breathing or long- standing cough) and other severe chronic obstructive pulmonary disease (group of lung diseases causing difficulty in breathing). Consult your doctor before using BRIMAZE T OPHTHALMIC SOLUTION. HEART DISEASEBRIMAZE T OPHTHALMIC SOLUTION is not recommended for use in patients with sinus bradycardia (a type of slow heartbeat), 2nd or 3rd degree heart block (delay in electrical conduction that triggers heart pumping), cardiac failure, cardiogenic shock (condition arising when heart is unable to pump enough blood to heart or brain) or heartbeat disorders. It should be used with caution in patients with heart disease such as coronary heart disease (causing chest pain or tightness, breathlessness or choking). Consult your before using BRIMAZE T OPHTHALMIC SOLUTION. OTHERSBefore using BRIMAZE T OPHTHALMIC SOLUTION, inform your doctor if you: have low blood pressure have breathing problems have poor blood circulation disease such as Raynaud’s disease or syndrome (condition marked by constriction of small blood vessels supplying blood to skin in response to cold) have diabetes have hyperthyroidism (raised levels of thyroid hormones) have tumour of adrenal glands are scheduled for eye surgery to lower pressure in eye are scheduled for any major surgery under general anaesthesia have signs of cerebral insufficiency (low blood flow to brain) such as stroke have depression have orthostatic hypotension (lowering of blood pressure on changing the posture) have thromboangitis obliterans (condition occurring due to inflammation of small blood vessels leading to blockage of blood vessels due to clot formation) have myasthenia gravis (condition causing weakness and fatigue of muscles) history of atopy (condition that makes you more vulnerable to allergies) and anaphylaxis (an allergic reaction causing shortness of breath, noisy breathing or collapse) Use in Paediatrics: BRIMAZE T OPHTHALMIC SOLUTION is not recommended for use in children and adolescents (aged below 17 years). Consult your child’s doctor for advice. Use in Geriatrics: BRIMAZE T OPHTHALMIC SOLUTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before using BRIMAZE T OPHTHALMIC SOLUTION.
Drug Interactions
SA. Drug-Drug Interactions: Before using BRIMAZE T OPHTHALMIC SOLUTION, inform your doctor if you are taking any of the following medicines: antihypertensives (medicines used to lower blood pressure) such as calcium antagonists (Ex. amlodipine, diltiazem), catecholamine-depleting drugs (Ex. reserpine) quinidine and cardiac glycosides (medicines used to manage heart failure or arrythmia) Ex. digitalis beta-blockers (medicines used to manage heart diseases) Ex. atenolol CNS depressants (medicines used to lower the brain activity and manage sleeplessness, anxiety or seizures) such as sedatives (Ex. amobarbital, morphine) and anaesthetics (Ex. propofol) phenelzine, tricyclic antidepressants such as amitriptyline and selective serotonin reuptake inhibitor Ex. fluoxetine, paroxetine (used to manage depression) medicines used to manage pain Ex. aspirin medicines used to manage diabetes Ex. metformin another eye drop used to lower high pressure in the eye (glaucoma) Ex. latanoprost medicines to manage severe allergic reactions Ex. chlorpheniramine, cetirizine medicines that affect the muscles in your blood vessels Ex. tadalafil medicines that affect some of the hormones in your body Ex. adrenaline and dopamine medicines used to manage heartburn or stomach ulcers Ex. omeprazole, pantoprazole Overdosage: If you or anyone else accidentally use too much of BRIMAZE T OPHTHALMIC SOLUTION, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of BRIMAZE T OPHTHALMIC SOLUTION are dizziness, headache, bradycardia (slowing of heartbeats), bronchospasm (tightening of airway muscles causing coughing and noisy breathing), cardiac arrest (sudden loss of heart function) or low blood pressure. SYNOPSIS Drug : Brimonidine, Timolol Pharmacological Category : Alpha-adrenergic receptor agonist, Beta-adrenergic receptor inhibitors Therapeutic Indication : Glaucoma, Ocular hypertension Dosage Forms : Eye drops MORE INFORMATION Keep BRIMAZE T OPHTHALMIC SOLUTION out of reach of children Store BRIMAZE T OPHTHALMIC SOLUTION at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
23 Dec 2022