BRILLO 180 Tablet 10's
Key Information
Generic Name
Generic Name Bempedoic Acid 180 mg
Manufacturer
Sun Pharmaceutical Industries Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
BRILLO 180 TABLET contains Bempedoic Acid which belongs to the group of medicines called Lipid lowering agents. It is used alone or together with cholesterol-lowering medicine (statins) to manage primary hypercholesterolaemia (condition in which blood cholesterol level rises above the normal limits) or mixed dyslipidaemia in adults when statins become intolerable to manage the condition in affected individuals. Mixed dyslipidaemia is a condition that occurs due to elevations in low-density lipoprotein (LDL) (known as bad cholesterol) and triglyceride levels accompanied with low levels of high-density lipoprotein (HDL) (known as good cholesterol) which is generally characterized by the symptoms such as tightness/pain in chest, dizziness, and awareness of heartbeat (palpitation). BRILLO 180 TABLET is not recommended for use if you are allergic to bempedoic acid. It should be used with caution in patients with severe liver or kidney problems, and in patients with a history of gout (condition caused due to raised blood uric acid levels). It is not recommended for use in pregnant and breastfeeding women, also, not recommended for use in children and adolescents (aged below 18 years) and it should be used with caution in elderly patients (aged 75 years and above). Consult your doctor before taking BRILLO 180 TABLET. Before taking BRILLO 180 TABLET, your doctor might advise you to take liver function test to assess your liver function. The most common
Uses
OF BRILLO 180 TABLETUsed alone or together with cholesterol-lowering medicine (statins) to manage: primary hypercholesterolaemia mixed dyslipidaemia
How It Works
BRILLO 180 TABLET works by inhibiting ATP citrate lyase (enzyme responsible for synthesis of cholesterol especially low-density lipoprotein (LDL) / bad cholesterol) which leads to enhanced LDL uptake and clearance in the liver resulting in lowered total blood cholesterol levels.
Directions for Use
Take BRILLO 180 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
BRILLO 180 TABLET are anaemia (lower number of red blood cells) and pain in shoulders, legs, or arms. Consult your doctor if any of the symptom worsens. USES OF BRILLO 180 TABLETUsed alone or together with cholesterol-lowering medicine (statins) to manage: primary hypercholesterolaemia mixed dyslipidaemia HOW BRILLO 180 TABLET WORKSBRILLO 180 TABLET works by inhibiting ATP citrate lyase (enzyme responsible for synthesis of cholesterol especially low-density lipoprotein (LDL) / bad cholesterol) which leads to enhanced LDL uptake and clearance in the liver resulting in lowered total blood cholesterol levels. DIRECTIONS FOR USETake BRILLO 180 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF BRILLO 180 TABLETCOMMON anaemia (reduced red blood cell count) gout (severe joint pain) due to increased blood uric acid levels pain in shoulders, legs, or arms UNCOMMON signs of high creatinine levels such as nausea, vomiting, or weakness signs of high urea nitrogen level in blood such as urge to urinate more or less often than normal, itching, weakness, and swelling (typically in legs, feet, or ankles) signs of decreased glomerular filtration rate (a measure of how properly your kidneys are working) such as urinating more/less, itching, weakness, swelling (in legs, feet, or ankles), muscle cramps, nausea, and vomiting
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedBRILLO 180 TABLET is not recommended for use during pregnancy and in women planning for pregnancy. Consult your doctor before taking BRILLO 180 TABLET. BREASTFEEDINGContraindicatedBRILLO 180 TABLET is not recommended for use in breastfeeding women. Consult your doctor taking BRILLO 180 TABLET. DRIVING AND USING MACHINESUse with CautionBRILLO 180 TABLET has no or negligible effect on your ability to drive and use machines. Consult your doctor before taking BRILLO 180 TABLET. KIDNEYUse with CautionBRILLO 180 TABLET should be used with caution in patients with severe kidney problems. Consult your doctor before taking BRILLO 180 TABLET. LIVERUse with CautionBRILLO 180 TABLET should be used with caution in patients with severe liver problems. Consult your doctor before taking BRILLO 180 TABLET. ALLERGYContraindicatedBRILLO 180 TABLET is not recommended for use if you are allergic to bempedoic acid, or any other ingredients of this medicine. USE IN PEDIATRICSContraindicatedBRILLO 180 TABLET is not recommended for use in children and adolescents (below 18 years of age). Consult your doctor before taking BRILLO 180 TABLET. USE IN GERIATRICSUse with CautionBRILLO 180 TABLET should be used with caution in elderly patients (above 75 years of age). Consult your doctor before taking BRILLO 180 TABLET. OTHERSBefore taking BRILLO 180 TABLET, inform your doctor if you: ever had a history of gout (condition caused due to raised blood uric acid levels)
Drug Interactions
SA. Drug-Drug Interactions: Before taking BRILLO 180 TABLET, inform your doctor, if you are taking any of the following medicines: other medicines used to lower blood cholesterol levels Ex. atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin medicines used to manage pulmonary artery hypertension Ex. bosentan medicines used to manage high blood pressure and heart failure Ex. fimasartan medicines used to manage hepatitis C Ex. asunaprevir, glecaprevir, grazoprevir, voxilaprevir Overdosage: If you or anyone else accidentally takes too much of BRILLO 180 TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Bempedoic Acid Pharmacological Category : Lipid lowering agents Therapeutic Indication : Primary hypercholesterolaemia or Mixed dyslipidaemia Dosage Forms : Tablet MORE INFORMATION Keep the medicine out of reach of children Store BRILLO 180 TABLET at room temperature
Frequently Asked Questions
Common questions and answers about BRILLO 180 Tablet 10's.
What is BRILLO 180 TABLET used for?
BRILLO 180 TABLET is used alone or together with cholesterol-lowering medicine (statins) to manage primary hypercholesterolaemia (condition that occurs due to high cholesterol levels in blood) or mixed dyslipidaemia (condition marked by elevations of bad cholesterol and triglyceride levels with low levels of good cholesterol in the blood) in adults when statins become intolerable to manage the condition in affected individuals.
What common side effects are seen with BRILLO 180 TABLET?
The most common side effects associated with the use of BRILLO 180 TABLET are anaemia (lower number of red blood cells), gout (increased blood uric acid levels), and pain in shoulders, legs, and/or arms. Consult your doctor if any of the symptom worsens.
Who should avoid taking BRILLO 180 TABLET?
BRILLO 180 TABLET is not recommended for use if you are allergic to bempedoic acid. It is also not recommended for use in pregnant and breastfeeding women. Also, not indicated for use in children and adolescents (below 18 years of age). Consult your doctor before taking the medicine.
How BRILLO 180 TABLET works?
BRILLO 180 TABLET works by inhibiting ATP citrate lyase (enzyme responsible for synthesis of cholesterol especially low-density lipoprotein (LDL) / bad cholesterol) which leads to enhanced LDL uptake and clearance in the liver resulting in lowered total blood cholesterol levels.
What if I forget to take a dose of BRILLO 180 TABLET?
You should take BRILLO 180 TABLET immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Is BRILLO 180 TABLET safe to use in children or elderly patients?
BRILLO 180 TABLET is not recommended for use in children and adolescents (below 18 years of age) and it should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking BRILLO 180 TABLET.
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
24 Feb 2023