BISOLET A Tablet 10's

s and serious side effects. The most common side effects of BISOLET A TABLET are headache, dizziness, stomach pain, tiredness, and nausea. Consult your doctor for advice if your symptoms get worse over time. USES OF BISOLET A TABLET Manage mild to moderate hypertension (high blood pressure) HOW BISOLET A TABLET WORKSBISOLET A TABLET helps to reduce high blood pressure, where amlodipine works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle, resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles, and bisoprolol is a beta-blocker that works by reducing the force of contraction of the heart muscles by blocking the effects of certain hormones called adrenaline and making the heart beat more easily, thus lowering the blood pressure. DIRECTIONS FOR USEAlways take BISOLET A TABLET as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole, and do not crush or chew the medicine. Do not stop taking BISOLET A TABLET without informing your doctor. SIDE EFFECTS OF BISOLET A TABLETCOMMON ankle swelling, oedema (fluid retention) headache dizziness, sleepiness coldness or numbness sensation in hands or feet palpitations (fast heartbeat), flushing stomach pain nausea, vomiting diarrhea, constipation altered bowel habits, indigestion weakness, tiredness muscle cramps visual disturbances, double vision low blood pressure UNCOMMON enlarged breast in men (gynecomastia) or discomfort in men irritability, sleep problems depression, mood changes, anxiety pain, numbness, tingling or prickling sensation in arms, legs, or feet dry mouth excess sweating uncontrolled shaking, loss of pain sensation orthostatic hypotension (dizziness while standing up from sitting or lying position) fainting altered taste sensation rhinitis (runny nose due to inflammation of the nose lining) urinary urgency at night-time, frequent urination, difficulty in passing urine ringing or buzzing sensation in ears chest pain, increased heart rate breathing difficulty, cough, inflammation of the mucosa swollen gums back, muscle or joint pain muscle weakness impotence (inability to achieve erection) increase or decrease in weight hair loss skin rash, itching, discoloration of the skin RARE confusion hearing problems dry eyes (reduced tear flow) nightmares, hallucinations Stop taking BISOLET A TABLET and contact your doctor immediately if you experience any of the following side effects: severe skin reactions such as stevens-johnson syndrome, toxic epidermal necrolysis (skin rash, itching, blistering, and reddening of skin all over the body, peeling and swelling of the skin, swelling of mucous membrane) signs of an inflamed pancreas (severe pain in abdomen and back, feeling unwell) slow or abnormal heartbeat, heart attack severe allergic reactions (such as swelling of the eyelids, face, neck, lips, mouth, tongue, throat, or airways, chest pain and sudden wheezing which can lead to difficulty in breathing or swallowing) dizziness, weakness or breathing difficulties HOW TO MANAGE SIDE EFFECTSHeadache: Apply a hot or cold-water bag to your head. Try taking a rest in a quiet and dark room. Drink tea or coffee. Consult your doctor if your symptoms worsen. Stomach pain: Take some time to rest and relax. Eat and drink slowly, or try to have smaller, more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor. Diarrhoea: Drink plenty of fluids, such as water, fruit juices, or electrolytes (ORS), to avoid dehydration in your body. Consult your doctor if your symptom does not improve. Constipation: Consume fiber-rich foods such as fresh fruits and vegetables and whole grain cereals, as well as plenty of fluids. Exercise more regularly and stay active. Consult your doctor if your symptoms worsen. Nausea and vomiting: Try to take this medicine with, or just after, a meal or snack, stick to simple meals and do not eat oil-rich or spicy food. Consult your doctor if your symptom does not improve. WARNING & PRECAUTIONSPREGNANCYBISOLET A TABLET is not recommended for use in pregnancy as it may cause serious harm to the pregnancy and unborn child by increasing the risk of miscarriage, premature birth, low blood sugar levels, and a decreased heart rate in the newborn baby. Consult your doctor for advice before taking BISOLET A TABLET. BREASTFEEDINGBISOLET A TABLET is not recommended for use by breastfeeding women. Consult your doctor for advice before taking BISOLET A TABLET. DRIVING AND USING MACHINESDo not drive or operate any machines if you experience tiredness, dizziness, or drowsiness, as it may impair your ability to drive or work. Consult your doctor for advice before taking BISOLET A TABLET. ALCOHOLConsumption of alcohol is not recommended during management with BISOLET A TABLET as it may increase the risk of tiredness, dizziness, and drowsiness. KIDNEYBISOLET A TABLET should be used with caution in patients with severe kidney disease and in patients who are undergoing dialysis. Consult your doctor for advice before taking BISOLET A TABLET. LIVERBISOLET A TABLET should be used with caution in patients with liver impairment. Consult your doctor for advice before taking BISOLET A TABLET. ALLERGYDo not take BISOLET A TABLET if you are allergic to Amlodipine and Bisoprolol or if you are allergic to other drugs of the same class (calcium-channel blockers such as nifedipine, felodipine, nimodipine). LUNGSBISOLET A TABLET is not recommended for use in patients with asthma or chronic lung disease. Consult your doctor for advice before taking BISOLET A TABLET. HEART DISEASEBISOLET A TABLET is not recommended for use in patients with cardiogenic shock (where the heart cannot pump sufficient blood around the body), aortic stenosis (narrowing of the aortic heart valve), chest pain at resting position, slow or irregular heart rate, very low blood pressure, heart failure or heart attack. Consult your doctor for advice before taking BISOLET A TABLET. OTHERSBISOLET A TABLET is not recommended for you, if you have: unmanageed phaeochromocytoma metabolic acidosis (excess acid in the blood) poor blood circulation problems (such as Raynaud’s syndrome causing the tingling sensation in fingers and toes or pale discoloration of the skin) Before taking BISOLET A TABLET, inform your doctor if you have: diabetes psoriasis (a skin condition) strict fasting from solid foods thyroid problem ongoing desensitization therapy (for management of allergic reactions such as hay fever) upcoming surgery or procedures peripheral artery disease (poor blood circulation to legs or rarely in arms due to fat deposition in arteries) Use in pediatrics: BISOLET A TABLET is not recommended for use in children and adolescents under 18 years of age. Consult your doctor for advice before taking BISOLET A TABLET. Use in geriatrics: BISOLET A TABLET should be used with caution in elderly patients especially when the dose is increased. Consult your doctor for advice before taking BISOLET A TABLET. INTERACTIONSA. Drug-Drug interactions: Before taking BISOLET A TABLET inform your doctor, if you are taking any of these medicines: ketoconazole, itraconazole (used to manage fungal infections) amiodarone, clonidine, digoxin, quinidine, moxonidine, methyldopa, lidocaine, verapamil, diltiazem (used to manage low blood pressure or heart problems) erythromycin, clarithromycin, rifampicin, telithromycin (used to manage bacterial infections) imipramine, amitriptyline, moclobemide, nefazodone (used to manage depression) ritonavir, nelfinavir, indinavir (used to manage HIV) phenobarbital, phenytoin, carbamazepine (used to manage seizures) st. john’s wort (herbal preparation used to manage depression) dexamethasone (used to manage rheumatoid arthritis) dantrolene infusion (used to manage severe body temperature abnormalities) simvastatin, (used to manage high cholesterol) cyclosporine, tacrolimus (used to alter the immune system response) sildenafil (used to manage impotence) levomepromazine (used to manage mental illness) aspirin, diclofenac, indomethacin, ibuprofen, naproxen (used to manage pain) mefloquine (used to manage malaria) adrenaline, dobutamine, noradrenaline (used to manage shock) salbutamol, theophylline (used to manage asthma) oxymetazoline, naphazoline (used to manage blocked nose) travoprost, bimatoprost, bisoprolol (used to manage glaucoma) dihydroergotamine, rizatriptan (used to manage headaches or migraine) insulin or oral diabetic agents such as metformin, vildagliptin (used to manage diabetes) B. Drug-Food interactions: Do not eat grapefruit or drink grapefruit juice while taking BISOLET A TABLET as it increases the level of this medicine in the blood, resulting in unpredictable blood pressure-lowering effects. Consult your doctor before taking BISOLET A TABLET. Overdosage: Consult your doctor right away if you or anyone else takes too much BISOLET A TABLET. Overdosage may cause side effects such as extreme dizziness, light-headedness, tiredness, fainting or weakness, breathing difficulty, wheezing, an increase in the frequency of urination, cold or sweaty skin due to a severe drop in blood pressure, low sugar levels in the blood, and a slow heart rate. SYNOPSIS Drug : Amlodipine, Bisoprolol Pharmacological Category : Calcium-channel blockers, Beta-blockers Therapeutic Indication : Hypertension Dosage Forms : Tablet MORE INFORMATION Keep BISOLET A TABLET out of reach from children Store at room temperature