Aztolet 10mg Tablet 10'S
Key Information
Generic Name
Generic Name Atorvastatin 10 mg+Clopidogrel 75 mg
Manufacturer
Sun Pharmaceutical Industries Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
AZTOLET 10MG TABLET is used to reduce elevated cholesterol and triglyceride levels in patients when a low-fat diet and lifestyle changes alone have failed. It is a combination of Atorvastatin and Clopidogrel which belongs to the group of medicines called HMG-CoA reductase inhibitors and Antiplatelet medicines respectively. It can also be used to reduce the risk of heart problems such as myocardial infarction, angina (chest pain), heart failure including stroke or revascularization procedures in adult patients with or without a clinically evident chronic heart disease. Along with management with AZTOLET 10MG TABLET, patient should follow an appropriate lipid-lowering diet as advised by their doctor to enhance recovery. Before using the medicine, inform your doctor if you have any liver or kidney disease. Patients with active liver disease should discontinue the use of AZTOLET 10MG TABLET as it may cause serious
Uses
OF AZTOLET 10MG TABLETIt is used to reduce: elevated cholesterol and triglyceride levels in patients when a low-fat diet and lifestyle changes alone have failed the risk of heart problems such as myocardial infarction (MI), angina, heart failure including stroke or revascularization procedures in adult patients with or without clinically evident of chronic heart disease
How It Works
AZTOLET 10MG TABLET reduces elevated cholesterol and risk of heart disease, where Atorvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol and Clopidogrel acts by inhibiting platelet aggregation, which is believed to be an important factor resulting in heart problems.
Directions for Use
Take AZTOLET 10MG TABLET as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition
Side Effects
grapefruit juice or alcohol while taking AZTOLET 10MG TABLET as it may lead to unwanted
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedAZTOLET 10MG TABLET is not recommended for use in pregnant women. BREASTFEEDINGContraindicatedAZTOLET 10MG TABLET is not recommended for use in breast-feeding women. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if your ability is affected after taking AZTOLET 10MG TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking AZTOLET 10MG TABLET. KIDNEYUse with CautionAZTOLET 10MG TABLET should be used with caution in patients with kidney disease. LIVERContraindicatedAZTOLET 10MG TABLET is not recommended for use in patients with active liver disease, including unexplained persistent elevations in hepatic transaminase levels. ALLERGYContraindicatedDo not take AZTOLET 10MG TABLET if you are allergic to Atorvastatin or Clopidogrel. LUNGSUse with CautionAZTOLET 10MG TABLET should be used with caution in patients with severe respiratory failure. USE IN PEDIATRICSContraindicatedAZTOLET 10MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety and effectiveness. USE IN GERIATRICSUse with CautionAZTOLET 10MG TABLET should be used with caution in elderly patients (65 years of age or above). During prolonged management with the medicine, your doctor will monitor you regularly. OTHERSAZTOLET 10MG TABLET is not recommended for use if you have: bleeding disorders Before taking AZTOLET 10MG TABLET, inform your physician if you have: hypothyroidism, diabetes repeated or unexplained muscle aches or pains personal history or family history of muscle problems previous muscular problems during management with other lipid-lowering medicines blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body) recent serious injury recent surgery (including dental surgery) any planned surgeries
Drug Interactions
s. The most common side effects are muscle pain, joint pain, diarrhoea, nausea, headache or stomach pain. Consult your doctor if any of the side effects worsen. USES OF AZTOLET 10MG TABLETIt is used to reduce: elevated cholesterol and triglyceride levels in patients when a low-fat diet and lifestyle changes alone have failed the risk of heart problems such as myocardial infarction (MI), angina, heart failure including stroke or revascularization procedures in adult patients with or without clinically evident of chronic heart disease HOW AZTOLET 10MG TABLET WORKSAZTOLET 10MG TABLET reduces elevated cholesterol and risk of heart disease, where Atorvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol and Clopidogrel acts by inhibiting platelet aggregation, which is believed to be an important factor resulting in heart problems. DIRECTIONS FOR USE Take AZTOLET 10MG TABLET as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition SIDE EFFECTS OF AZTOLET 10MG TABLETCommon side effects of AZTOLET 10MG TABLET: diarrhoea stomach pain indigestion or heartburn constipation, flatulence, indigestion joint pain, muscle and back pain Stop taking AZTOLET 10MG TABLET and contact your doctor immediately if you experience any of the following side effects: unexpected or unusual bleeding or bruising, hematoma signs of liver problems such as yellowing of the skin and/or the eyes (jaundice), whether associated with bleeding which appears under the skin as red pinpoint dots signs of infection or extreme tiredness (due to decrease of some blood cells) WARNING & PRECAUTIONSPREGNANCYContraindicatedAZTOLET 10MG TABLET is not recommended for use in pregnant women. BREASTFEEDINGContraindicatedAZTOLET 10MG TABLET is not recommended for use in breast-feeding women. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if your ability is affected after taking AZTOLET 10MG TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking AZTOLET 10MG TABLET. KIDNEYUse with CautionAZTOLET 10MG TABLET should be used with caution in patients with kidney disease. LIVERContraindicatedAZTOLET 10MG TABLET is not recommended for use in patients with active liver disease, including unexplained persistent elevations in hepatic transaminase levels. ALLERGYContraindicatedDo not take AZTOLET 10MG TABLET if you are allergic to Atorvastatin or Clopidogrel. LUNGSUse with CautionAZTOLET 10MG TABLET should be used with caution in patients with severe respiratory failure. USE IN PEDIATRICSContraindicatedAZTOLET 10MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety and effectiveness. USE IN GERIATRICSUse with CautionAZTOLET 10MG TABLET should be used with caution in elderly patients (65 years of age or above). During prolonged management with the medicine, your doctor will monitor you regularly. OTHERSAZTOLET 10MG TABLET is not recommended for use if you have: bleeding disorders Before taking AZTOLET 10MG TABLET, inform your physician if you have: hypothyroidism, diabetes repeated or unexplained muscle aches or pains personal history or family history of muscle problems previous muscular problems during management with other lipid-lowering medicines blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body) recent serious injury recent surgery (including dental surgery) any planned surgeries INTERACTIONSA. Drug-Drug interactions: Before taking AZTOLET 10MG TABLET inform your doctor, if you are taking any of these medicines: Anti-lipidemic agents (Ex. cholestyramine, colestipol, gemfibrozil, ezetimibe) Thienopyridine (Ex. ticlopidine) Anti-depressants (Ex. fluoxetine, fluvoxamine, citalopram, sertraline, venlafaxine, duloxetine, desvenlafaxine) Vitamins (Ex. niacin) Immunosuppressants (Ex. cyclosporin) Antibiotics (Ex. telithromycin, clarithromycin, fusidic acid) HIV protease inhibitors (ritonavir or lopinavir) Anti-fungal (Ex. itraconazole) proton pump inhibitors (Ex. omeprazole and esomeprazole) Ant-diabetic agents (Ex. repaglinide) Antimicrotubule agents (Ex. Paclitaxel) Anti-TB agents (Ex. rifampin) Cardiac glycosides (Ex. digoxin) Oral contraceptives (Ex. norethindrone, ethinyl estradiol) Anti-gout agents (Ex. colchicine) non-steroidal anti-inflammatory agents (Ex. aspirin) Anti-coagulants (Ex. heparin and warfarin) St. john’s wort B. Drug-Food interaction: While taking AZTOLET 10MG TABLET, avoid taking large quantities (not more than one or two small glasses) of grapefruit juice as it can alter the effects of this medicine resulting in undesired therapeutic outcomes. Overdosage: If you or anyone else accidentally takes too much of AZTOLET 10MG TABLET, contact your doctor immediately or go to a hospital straight away because of increased risk of bleeding. SYNOPSIS Drug : Atorvastatin, Clopidogrel Pharmacological Category : HMG-CoA reductase inhibitors, Anti-platelet medication Therapeutic Indication : Controls blood cholesterol levels, Reduces the risk of heart diseases Dosage Forms : Tablet, Capsule MORE INFORMATION
Frequently Asked Questions
Common questions and answers about Aztolet 10mg Tablet 10'S.
What is AZTOLET 10MG TABLET used for?
AZTOLET 10MG TABLET, a combination of atorvastatin and clopidogrel, is used to reduce the risk of heart attacks, strokes, and other cardiovascular events. Atorvastatin lowers "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL). Clopidogrel prevents platelets from clumping together, reducing the risk of blood clots. Together, they protect against complications related to high cholesterol and blood clots.
How AZTOLET 10MG TABLET works for heart attack?
AZTOLET 10MG TABLET reduces the risk of heart attacks by targeting two main factors: high cholesterol and blood clots. Atorvastatin inhibits an enzyme in the liver responsible for cholesterol production, reducing plaque buildup in blood vessels. Clopidogrel prevents platelets from sticking together, maintaining smooth blood flow and minimizing clot formation. These actions ensure that blood vessels remain open, reducing strain on the heart.
What high cholesterol levels can lead to?
High cholesterol can lead to the formation of fatty deposits (plaques) in blood vessels, narrowing them and restricting blood flow. This condition, known as atherosclerosis, increases the risk of heart attacks, strokes, and peripheral artery disease. Untreated high cholesterol can also lead to hypertension and other complications like kidney disease or chest pain (angina).
Can AZTOLET 10MG TABLET be used in obese individuals?
Yes, AZTOLET 10MG TABLET is often prescribed for obese individuals who are at higher risk of cardiovascular diseases due to elevated cholesterol levels and a greater likelihood of blood clots. However, it should be combined with lifestyle changes like a healthy diet, regular exercise, and weight management for optimal results. Make sure to take this medicine under medical supervision only if you are obese and having blood tests indication high cholesterol or triglyceride levels.
Can AZTOLET 10MG TABLET reduces body weight?
No, AZTOLET 10MG TABLET is not designed for weight loss. While atorvastatin helps manage cholesterol levels, and clopidogrel reduces clotting risk, neither directly affects body weight. Weight loss in patients taking this medication often results from lifestyle modifications, such as a healthy diet and increased physical activity.
Can AZTOLET 10MG TABLET be used during pregnancy?
No, AZTOLET 10MG TABLET is not recommended during pregnancy. Atorvastatin may harm the developing fetus, and clopidogrel should only be used if absolutely necessary, as its safety during pregnancy is not well established. If you are pregnant or planning to conceive, consult your doctor for alternative treatments.
What diet and lifestyle changes should be adopted for high cholesterol?
To manage high cholesterol, adopt a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins like fish and chicken. Limit saturated fats, trans fats, and added sugars. Regular physical activity, maintaining a healthy weight, avoiding smoking, and limiting alcohol intake are also essential. These habits enhance the effectiveness of AZTOLET 10MG TABLET.
What foods should be avoided if you are having high cholesterol?
Avoid foods high in saturated and trans fats, such as fried foods, full-fat dairy products, processed meats, and baked goods made with hydrogenated oils. Minimize consumption of red meat, butter, and fast foods. Instead, choose heart-healthy fats from nuts, seeds, avocados, and olive oil.
Are there any medicines that should be avoided while taking AZTOLET 10MG TABLET?
Yes, some medications can interact with AZTOLET 10MG TABLET, including, blood thinners like warfarin (increased bleeding risk), certain antibiotics or antifungals (e.g., clarithromycin, ketoconazole), immunosuppressants (e.g., cyclosporine), anti-seizure medications (e.g., phenytoin). Always inform your doctor about all the medicines and supplements you are taking.
What precautions must be followed while taking AZTOLET 10MG TABLET?
Avoid alcohol, as it can increase the risk of liver damage. Take the medication exactly as prescribed. Monitor your cholesterol and liver function tests regularly. Report any unusual bruising, bleeding, or muscle pain to your doctor. Avoid grapefruit or its juice, as it may interfere with atorvastatin's metabolism.
Is AZTOLET 10MG TABLET safe?
AZTOLET 10MG TABLET is generally safe when taken as prescribed. However, like all medicines, it may cause side effects in some individuals. Regular follow-ups and monitoring are crucial to ensure safety and effectiveness. Speak to your doctor if you have concerns or pre-existing conditions.
How long should AZTOLET 10MG TABLET be used?
The duration of AZTOLET 10MG TABLET therapy depends on your condition and response to therapy. In many cases, it is used as a long-term medication to prevent recurring cardiovascular events. Regular check-ups will help your doctor decide the appropriate duration for you.
Can I stop using AZTOLET 10MG TABLET once after I feel better?
No, do not stop taking AZTOLET 10MG TABLET without consulting your doctor. Discontinuing the medication can increase your risk of a heart attack, stroke, or other complications. Always follow your doctor’s instructions regarding dose adjustments or discontinuation.
What are the common side effects of using AZTOLET 10MG TABLET?
Common side effects of AZTOLET 10MG TABLET include headache, dizziness, nausea, muscle pain, and upset stomach. Rarely, it can cause severe side effects like liver damage, severe bleeding, or allergic reactions. Inform your doctor if you experience any unusual symptoms.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
19 Nov 2024