AXPERO 1 Tablet 14's
Key Information
Generic Name
Generic Name Axitinib 1 mg
Manufacturer
Intas Pharmaceuticals Ltd
Variant
14 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
AXPERO 1 TABLET contains Axitinib which belongs to the group of medicines called Kinase inhibitors. It manages advanced kidney tumour in adults, when another medicine (called sunitinib or a cytokine) is no longer stopping disease from progressing. AXPERO 1 TABLET works by reducing the blood supply to the cancer cells and slows down the growth of cancer. Avoid consumption of grapefruit during treatment with AXPERO 1 TABLET. Before taking AXPERO 1 TABLET, inform your doctor if you have high blood pressure, have had a recent problem with blood clots in your veins and arteries including stroke, heart attack, embolism, or thrombosis, thyroid gland problems, bleeding problems, aneurysm, liver problem or have an operation or an unhealed wound. AXPERO 1 TABLET is generally not recommended for use in pregnant or breastfeeding women and in children (aged below 18 years) unless advised by the doctor. The most common
Uses
OF AXPERO 1 TABLET It manages advanced kidney cancer in adults
How It Works
AXPERO 1 TABLET targets and inhibits specific enzymes (kinases) involved in the formation of new blood vessels (angiogenesis) that cancer cells need to grow. By blocking these enzymes, it helps to starve the cancer of nutrients and slows its progression.
Directions for Use
Take AXPERO 1 TABLETas advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking AXPERO 1 TABLETare diarrhoea, nausea or vomiting, stomach ache, indigestion, soreness of the mouth, tongue or throat, and constipation. Consult your doctor if any of the side effects worsen. USES OF AXPERO 1 TABLET It manages advanced kidney cancer in adults HOW AXPERO 1 TABLET WORKSAXPERO 1 TABLET targets and inhibits specific enzymes (kinases) involved in the formation of new blood vessels (angiogenesis) that cancer cells need to grow. By blocking these enzymes, it helps to starve the cancer of nutrients and slows its progression. DIRECTIONS FOR USETake AXPERO 1 TABLETas advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF AXPERO 1 TABLETCOMMON High blood pressure Diarrhoea, nausea or vomiting, stomachache, indigestion, soreness of the mouth, tongue or throat, constipation Shortness of breath, cough, hoarseness Lack of energy, feeling weak or tired Redness and swelling of the palms of the hands or soles of the feet (hand-foot syndrome), skin rash, dryness of the skin Joint pain, pain in hands or feet Loss of appetite Weight loss Headache, taste disturbance or loss of taste Dehydration Kidney problems Flatulence (wind), haemorrhoids, bleeding from gums, bleeding from the rectum, a burning or stinging sensation in the mouth Muscle pain Nose bleeding Skin itching, redness of the skin, hair loss Ringing/sound in the ears (tinnitus) Swelling of the abdomen, legs, or ankles, protruding neck veins, excessive tiredness, shortness of breath (signs of heart failure events) Fistula Dizziness Inflammation of the gall bladder Stop taking AXPERO 1 TABLETand contact your doctor immediately if you experience any of the following side effects: Heart failure events (excessive tiredness, swelling of the abdomen, legs, or ankles, shortness of breath, or protruding neck veins) Blood clots in your veins and arteries (types of blood vessels), including stroke, heart attack, embolism, or thrombosis (symptoms such as chest pain or pressure; pain in your arms, back, neck or jaw; shortness of breath; numbness or weakness on one side of your body; trouble talking; headache; vision changes or dizziness.) Bleeding (symptoms of black tarry stools, coughing up of blood or bloody sputum, or change in your mental status) Hole in the stomach or intestine or formation of fistula Severe increase in blood pressure (hypertensive crisis), severe headache, or severe chest pain. Reversible swelling of the (symptoms such as headache, confusion, seizures (fits), or changes in vision with or without high blood pressure)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedAXPERO 1 TABLET is not recommended for use in pregnant women or if you are planning to have a baby as it can harm the unborn child. Use a reliable method of contraception and up to 1 week after the last dose of AXPERO 1 TABLET, to prevent pregnancy. BREASTFEEDINGContraindicatedAXPERO 1 TABLET is not recommended for use in breastfeeding. If you are breast-feeding, your doctor should discuss with you whether to discontinue breast-feeding or discontinue AXPERO 1 TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or use machines while taking AXPERO 1 TABLETas you may feel tired or dizziness. LIVERUse with CautionAXPERO 1 TABLET should be used with caution in patients with liver problems. Consult your doctor before taking it. ALLERGYContraindicatedDo not take AXPERO 1 TABLET if you are allergic to Axitinib. HEART DISEASEUse with CautionAXPERO 1 TABLET should be used with caution in patients with heart problems (stroke, heart attack, embolism, or thrombosis) and high blood pressure. Consult your doctor before taking AXPERO 1 TABLET. USE IN PEDIATRICSContraindicatedAXPERO 1 TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your child’s doctor for advice. OTHERSBefore taking AXPERO 1 TABLET, inform your doctor if you: have had a recent problem with blood clots have thyroid gland problems have bleeding problems have aneurysm have an operation or an unhealed wound Are lactose intolerant
Drug Interactions
SA. Drug-Drug interactions: Before taking AXPERO 1 TABLET, inform your doctor if you are taking any of the following medicines: Antifungals (Ex. ketoconazole or itraconazole) Antibacterials (Ex. clarithromycin, erythromycin or telithromycin) Anti-HIV agents (Ex. atazanavir, indinavir, nelfinavir, ritonavir or saquinavir) Antidepressants (Ex. Nefazodone, St. John’s wort) Antituberculosis (Ex. rifampicin, rifabutin or rifapentine) Steroids (Ex. Dexamethasone) Anti-epileptics (Ex. phenytoin, carbamazepine or phenobarbital) Antiasthma (Ex. Theophylline) B. Drug-Food interactions: Do not take AXPERO 1 TABLET with grapefruit or grapefruit juice, as it may increase the chance of side effects. Overdosage: If you or anyone else accidentally take too much of AXPERO 1 TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Axitinib Pharmacological Category : Kinase inhibitors Therapeutic Indication : Advance kidney tumour Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep AXPERO 1 TABLETout of reach of children Store at room temperature
Frequently Asked Questions
Common questions and answers about AXPERO 1 Tablet 14's.
What is AXPERO 1 TABLET?
AXPERO 1 TABLET is a targeted therapy drug used primarily to manage advanced renal cell carcinoma (RCC), a type of kidney cancer. It works by inhibiting the growth of blood vessels that supply cancers, thereby slowing down the growth and spread of cancer cells.
How does AXPERO 1 TABLET work?
AXPERO 1 TABLET is a tyrosine kinase inhibitor (TKI). It targets and inhibits specific enzymes (kinases) involved in the formation of new blood vessels (angiogenesis) that cancer cells need to grow. By blocking these enzymes, it helps to starve the cancer cells for nutrients and slows its progression.
How is AXPERO 1 TABLET administered?
AXPERO 1 TABLET is usually taken orally in the form of tablets. The dosage and schedule will be determined by your healthcare provider based on your specific condition and response to treatment. It is typically taken twice daily.
What are the common side effects of AXPERO 1 TABLET?
The most common side effects of taking AXPERO 1 TABLETare diarrhoea, nausea or vomiting, stomach ache, indigestion, soreness of the mouth, tongue or throat, and constipation. Consult your doctor if any of the side effects worsen.
What are the serious side effects?
Serious side effects may include severe high blood pressure, heart problems, liver problems. bleeding issues and gastrointestinal perforation.
How should AXPERO 1 TABLET be taken?
Take AXPERO 1 TABLETas advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double up on doses to make up for a missed one. Contact your healthcare provider for specific instructions.
Are there any interactions with other medications?
AXPERO 1 TABLET can interact with other medications, including certain antibiotics, antifungals, and medications used for high blood pressure. Inform your healthcare provider about all the medications, supplements, and herbs you are taking.
Who should not take AXPERO 1 TABLET?
AXPERO 1 TABLET should not be taken by individuals who are allergic to it or any of its ingredients. Additionally, it may not be suitable for people with certain health conditions, so discuss your medical history with your healthcare provider.
What should I do in case of an emergency?
Seek immediate medical help if you experience severe side effects or symptoms such as chest pain, severe headache, vision changes, or signs of bleeding, seek immediate medical attention.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
14 Sep 2024