Atrest 25mg Tablet 10'S
Key Information
Generic Name
Generic Name Tetrabenazine 25 mg
Manufacturer
Centaur Pharmaceuticals Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ATREST 25MG TABLET contains Tetrabenazine which belongs to the group of medicines called Vesicular monoamine transporter 2 inhibitors. ATREST 25MG TABLET is used to manage diseases that cause hyperkinetic motor disorders (such as jerky, irregular, uncontrollable movements) associated with Huntington's chorea (an inherited neurodegenerative disease) in affected individuals. ATREST 25MG TABLET is not recommended for use in patients allergic to Tetrabenazine. It is also not recommended for use in patients suffering from Parkinson-like symptoms, depression, active suicidal thoughts, pheochromocytoma (tumor of the adrenal gland), and/or kidney disorders. Before taking ATREST 25MG TABLET, inform your doctor if you are intolerant to certain sugars (such as lactose), and/or have heart problems (such as long QT syndrome, heart rhythm disorders), liver problems (such as mild, moderate/severe hepatic disorders). ATREST 25MG TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. It is not recommended for use in breastfeeding women. The medicine is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor. The most common
Uses
OF ATREST 25MG TABLET Manage diseases that cause hyperkinetic motor disorders (such as jerky, irregular, uncontrollable movements) associated with Huntington's chorea (an inherited neurodegenerative disease) in affected individuals
How It Works
ATREST 25MG TABLET works by inhibiting the absorption of certain chemicals (dopamine, serotonin) in brain which results in improved movements thus managing hyperkinetic motor disorders associated with Huntington's chorea in affected individuals.
Directions for Use
Take ATREST 25MG TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking ATREST 25MG TABLET are confusion, anxiety, sleeplessness, low blood pressure, nausea, vomiting, diarrhea, and/or constipation. Consult your doctor if any these symptoms worsen. USES OF ATREST 25MG TABLET Manage diseases that cause hyperkinetic motor disorders (such as jerky, irregular, uncontrollable movements) associated with Huntington's chorea (an inherited neurodegenerative disease) in affected individuals HOW ATREST 25MG TABLET WORKSATREST 25MG TABLET works by inhibiting the absorption of certain chemicals (dopamine, serotonin) in brain which results in improved movements thus managing hyperkinetic motor disorders associated with Huntington's chorea in affected individuals. DIRECTIONS FOR USETake ATREST 25MG TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF ATREST 25MG TABLETCOMMON drowsiness (with higher dosages) Parkinson-like symptoms (such as uncontrollable movements of the head, legs, hands, arms) confusion, anxiety sleeplessness low blood pressure dysphagia (difficulty in swallowing) nausea, vomiting, diarrhea, constipation sweating UNCOMMON mental changes (such as confusion, hallucinations) stiffness in your muscles fever RARE signs of Neuroleptic malignant syndrome (life threatening reaction to antipsychotic drug) such as mental changes (confusion, hallucinations), stiffness in muscles, and/or temperature Stop taking ATREST 25MG TABLET and contact your doctor immediately if you experience any of the following side effects: feeling sad/depressed suicidal thoughts have/plan to hurt yourself intentionally
Warnings & Precautions
& PRECAUTIONSPREGNANCYATREST 25MG TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine. BREASTFEEDINGATREST 25MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESDo not drive/operate machines if you feel drowsy after taking ATREST 25MG TABLET. ALCOHOLAvoid consumption of alcohol while taking ATREST 25MG TABLET since the medicine may make you feel abnormally sleepy. KIDNEYATREST 25MG TABLET is not recommended for use in patients with kidney disorders. Consult your doctor before taking ATREST 25MG TABLET. LIVERATREST 25MG TABLET should be used with caution in patients with liver problems such as mild, moderate, and/or severe hepatic disorders. Consult your doctor before taking ATREST 25MG TABLET. ALLERGYDo not take ATREST 25MG TABLET if you are allergic to Tetrabenazine, and/or any other ingredients of this medicine. HEART DISEASEATREST 25MG TABLET should be used with caution in patients with heart problems such as long QT syndrome, and/or problems associated with heart rhythm. Consult your doctor before taking ATREST 25MG TABLET. OTHERSATREST 25MG TABLET is not recommended for use if you: suffer from Parkinson-like symptoms are diagnosed with depression which has not been managed or difficult to manage have active suicidal thoughts have pheochromocytoma (tumor of the adrenal gland) have prolactin-dependent tumors such as pituitary/ breast cancer Before taking ATREST 25MG TABLET, inform your doctor if you: are a slow/intermediate metabolizer of an enzyme called CYP2D6 (enzyme responsible for metabolism of medicines) are intolerant to certain sugars such as lactose Use in Pediatrics: ATREST 25MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking ATREST 25MG TABLET. Use in Geriatrics: ATREST 25MG TABLET should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking ATREST 25MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking ATREST 25MG TABLET, inform your doctor if you are taking any of the following medicine: reserpine (used to control high blood pressure and manage psychosis) antidepressants (used to manage depression) such as MAO inhibitors (Ex. phenelzine, selegiline) levodopa (used to manage Parkinson’s disease) opioids (used to control pain) Ex. oxycodone, hydrocodone antihypertensive drugs (used to manage high blood pressure) Ex. telmisartan, chlorthalidone beta blockers (used to manage heart problems) Ex. acebutolol, atenolol medicines used to manage psychotic disorders such as hypnotics (Ex. ambien, belsomra), neuroleptics (Ex. butaperazine) CYP2D6 inhibitors (medicines used to reduce the metabolism of certain medicines) Ex. fluoxetine, paroxetine, terbinafine, moclobemide, quinidine medicines that prolong the QTc interval in the ECG (Ex. haloperidol, droperidol) certain antibiotics (used to manage bacterial infections) Ex. gatifloxacin, moxifloxacin medicines used to manage heart rhythm conditions (Ex. quinidine, procainamide, amiodarone, sotalol) Overdosage: If you or anyone else accidentally take too much of ATREST 25MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are uncontrollable muscle spasms (affecting eyes, head, neck and body), uncontrolled rolling of eyes, excessive blinking of eye, nausea, vomiting, diarrhea, sweating, dizziness, feeling cold, confusion, hallucinations, drowsiness, redness/inflammation, and/or tremor. SYNOPSIS Drug : Tetrabenazine Pharmacological Category : Vesicular monoamine transporter 2 inhibitor Therapeutic Indication : Hyperkinetic motor disorders associated with Huntington's chorea Dosage Forms : Tablet MORE INFORMATION Keep ATREST 25MG TABLET out of reach of children Store ATREST 25MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
20 Dec 2022